Laszlo Vutskits

Laszlo Vutskits

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Laszlo Vutskits

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Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.

EMBO Rep 2020 Feb 17:e48880. Epub 2020 Feb 17.

Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.15252/embr.201948880DOI Listing
February 2020

Reporting Laboratory and Animal Research in ANESTHESIOLOGY: The Importance of Sex as a Biologic Variable.

Anesthesiology 2019 Nov;131(5):949-952

From the Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University Hospitals of Geneva, Geneva, Switzerland (L.V.) the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California (J.D.C.) the Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (E.D.K.).

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http://Insights.ovid.com/crossref?an=00000542-900000000-9646
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http://dx.doi.org/10.1097/ALN.0000000000002945DOI Listing
November 2019

Perspectives on Dexmedetomidine Use for Neurosurgical Patients.

J Neurosurg Anesthesiol 2019 Oct;31(4):366-377

Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1097/ANA.0000000000000554DOI Listing
October 2019

GAS, PANDA, and MASK: No Evidence of Clinical Anesthetic Neurotoxicity!

Anesthesiology 2019 10;131(4):762-764

From the Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University Hospitals of Geneva, Geneva, Switzerland (L.V.) Harvard Medical School, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham & Women's Hospital, Boston, Massachusetts (D.J.C.).

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http://Insights.ovid.com/crossref?an=00000542-201910000-0000
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http://dx.doi.org/10.1097/ALN.0000000000002863DOI Listing
October 2019

Increased Reactivity of the Mesolimbic Reward System after Ketamine Injection in Patients with Treatment-resistant Major Depressive Disorder.

Anesthesiology 2019 Jun;130(6):923-935

From the Department of Neuroscience, Faculty of Medicine (V.S., J.H., D.W., A.D., S.S., L.V.) Geneva Neuroscience Center (V.S., J.H., D.W., A.D., S.S., L.V.) Swiss Center for Affective Sciences (V.S., J.H., D.W., S.S.), University of Geneva, Geneva, Switzerland Department of Mental Health and Psychiatry, Service of Psychiatric Specialties (S.V., G.M., V.B., A.D., J.-M.A., M.K.) Department of Anesthesiology, Pharmacology, and Intensive Care (L.V.), University Hospitals of Geneva, Geneva, Switzerland Faculty of Medicine, University of Namur, Namur, Belgium (M.D.).

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http://dx.doi.org/10.1097/ALN.0000000000002667DOI Listing
June 2019

European Society of Anaesthesiology Task Force on Nitrous Oxide: a narrative review of its role in clinical practice.

Br J Anaesth 2019 May 22;122(5):587-604. Epub 2019 Feb 22.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals Geneva, Genève, Switzerland.

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http://dx.doi.org/10.1016/j.bja.2019.01.023DOI Listing
May 2019

Perspectives on Dexmedetomidine Use for Neurosurgical Patients.

J Neurosurg Anesthesiol 2019 Oct;31(4):366-377

Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1097/ANA.0000000000000554DOI Listing
October 2019

Anesthesia and the developing brain: A way forward for laboratory and clinical research.

Paediatr Anaesth 2018 09 16;28(9):758-763. Epub 2018 Aug 16.

Department of Anesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/pan.13455DOI Listing
September 2018

Targeting Microglia: A New Avenue for Anesthesia Neuroprotection after Brain Injury?

Anesthesiology 2018 08;129(2):232-234

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Switzerland (L.V.) Department of Anesthesia and Perioperative Care, University of California, San Francisco, California (J.W.S.).

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http://dx.doi.org/10.1097/ALN.0000000000002272DOI Listing
August 2018

Development of inhibitory synaptic inputs on layer 2/3 pyramidal neurons in the rat medial prefrontal cortex.

Brain Struct Funct 2018 May 10;223(4):1999-2012. Epub 2018 Jan 10.

Department of Basic Neuroscience, University of Geneva Medical School, Geneva, Switzerland.

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http://dx.doi.org/10.1007/s00429-017-1602-0DOI Listing
May 2018

SmartTots: Quo Vadis?

Authors:
Laszlo Vutskits

Anesth Analg 2018 04;126(4):1124-1126

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland.

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http://Insights.ovid.com/crossref?an=00000539-201804000-0000
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http://dx.doi.org/10.1213/ANE.0000000000002891DOI Listing
April 2018

Pediatric perioperative outcomes group: Defining core outcomes for pediatric anesthesia and perioperative medicine.

Paediatr Anaesth 2018 04;28(4):314-315

Developmental Neurosciences Program, UCL Great Ormond Street Institute of Child Health, Department of Anaesthesia and Pain Medicine, Great Ormond Street Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1111/pan.13354DOI Listing
April 2018

When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children.

Front Pharmacol 2018 5;9:148. Epub 2018 Mar 5.

Division of Clinical Pharmacology and Toxicology, Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, University of GenevaGeneva, Switzerland.

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http://journal.frontiersin.org/article/10.3389/fphar.2018.00
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http://dx.doi.org/10.3389/fphar.2018.00148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844975PMC
March 2018

An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia.

Anesthesiology 2018 01;128(1):85-96

From the Department of Anesthesiology (V.A.O., Y.J.) and Division of Biostatistics and Epidemiology (L.D.), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Anaesthesia, Children's Hospital at Westmead, Sydney, New South Wales, Australia (J.S.); Discipline of Child and Adolescent Health, University of Sydney, Sydney, New South Wales, Australia (J.S.); Anaesthesia and Pain Management Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia (V.M., B.S., A.D.); Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (C.G.W., F.X.M., C.D.K.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, China (G.Y.); Department of Anesthesiology, Second Affiliated Hospital and Yuying Children's Hospital of Whenzhou Medical University, Wenzhou, Zhejiang, China (H.L.); Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia (B.S., A.D.); Department of Anesthesiology, Pharmacology, and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland (L.V.); Department of Anesthesiology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands (J.C.d.G.); School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia (B.S.v.U.-S.); and Department of Anaesthesia and Pain Management, Princess Margaret Hospital for Children, Perth, Western Australia, Australia (B.S.v.U.-S.).

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http://dx.doi.org/10.1097/ALN.0000000000001920DOI Listing
January 2018

General Anesthetics to Treat Major Depressive Disorder: Clinical Relevance and Underlying Mechanisms.

Authors:
Laszlo Vutskits

Anesth Analg 2018 01;126(1):208-216

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1213/ANE.0000000000002594DOI Listing
January 2018

Perioperative Hypotension in Infants: Insights From the GAS Study.

Anesth Analg 2017 09;125(3):719-720

From the *Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland; and †Department of Anaesthesia, the Children's Hospital at Westmead, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1213/ANE.0000000000001959DOI Listing
September 2017

Can We Really Suggest that Anesthesia Might Cause Attention-deficit/Hyperactivity Disorder?

Anesthesiology 2017 08;127(2):209-211

From the Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia (D.E.); Melbourne Children's Trials Centre (A.J.D.), Murdoch Childrens Research Institute (D.E.), Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia (D.E.); Department of Anesthesiology, Pharmacology, and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland (L.V.); Department of Basic Neuroscience, University of Geneva Medical School, Geneva, Switzerland (L.V.); and Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia (A.J.D.).

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http://dx.doi.org/10.1097/ALN.0000000000001736DOI Listing
August 2017

Update on developmental anesthesia neurotoxicity.

Curr Opin Anaesthesiol 2017 Jun;30(3):337-342

aDepartment of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva bDepartment of Basic Neurosciences, University of Geneva Medical School, Geneva, Switzerland cDepartment of Anaesthesia, Royal Children's Hospital dMelbourne Children's Trials Centre, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/ACO.0000000000000461DOI Listing
June 2017

K-Cl Cotransporter 2-mediated Cl- Extrusion Determines Developmental Stage-dependent Impact of Propofol Anesthesia on Dendritic Spines.

Anesthesiology 2017 05;126(5):855-867

From the Department of Biosciences and Neuroscience Center (HiLIFE), University of Helsinki, Helsinki, Finland (M.P., M.M., P.B., K.K.); Division of Biological and Environmental Sciences and Technology, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia (H.F.); Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland (A.B., T.B., C.-M.L., L.V.); Department of Fundamental Neurosciences, University of Geneva Medical School, Geneva, Switzerland (A.B., T.B., K.D., L.V.); and Institute of Experimental Medicine of the Hungarian Academy of Sciences, Budapest, Hungary (K.D.). Current position: Institute of Physiology I, Westfälische Wilhelms-University Münster, Münster, Germany (P.B.).

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http://dx.doi.org/10.1097/ALN.0000000000001587DOI Listing
May 2017

The new FDA drug safety communication on the use of general anesthetics in young children: what should we make of it?

Paediatr Anaesth 2017 04;27(4):336-337

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/pan.13122DOI Listing
April 2017

Lasting impact of general anaesthesia on the brain: mechanisms and relevance.

Nat Rev Neurosci 2016 10;17(11):705-717

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Room 4310, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/nrn.2016.128DOI Listing
October 2016

Reply to Hooijmans, Carlijn; Wever, Kimberley; Ritskes-Hoitinga, Merel; Scheffer, Gert Jan, regarding their comment 'The usefulness of systematic reviews of animal studies; shooting the messenger'.

Paediatr Anaesth 2016 08;26(8):853-4

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/pan.12958DOI Listing
August 2016

More Than Anyone Else: Preemies Need Good Analgesia.

Authors:
Laszlo Vutskits

Anesthesiology 2016 Apr;124(4):758-60

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1097/ALN.0000000000001018DOI Listing
April 2016

Anesthesia-related neurotoxicity and the developing brain:--do not overreact. A commentary.

Acta Anaesthesiol Belg 2015 ;66(3):63-5

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February 2016

Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats.

Toxicol Sci 2016 Jan 30;149(1):121-33. Epub 2015 Sep 30.

*Center for Brain Repair and Rehabilitation, University of Gothenburg, Gothenburg, SE-40530, Sweden; *Center for Brain Repair and Rehabilitation, University of Gothenburg, Gothenburg, SE-40530, Sweden;

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http://dx.doi.org/10.1093/toxsci/kfv219DOI Listing
January 2016

What lessons for clinical practice can be learned from systematic reviews of animal studies? The case of anesthetic neurotoxicity.

Paediatr Anaesth 2016 Jan;26(1):4-5

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/pan.12826DOI Listing
January 2016

Early exposure to volatile anesthetics impairs long-term associative learning and recognition memory.

PLoS One 2014 28;9(8):e105340. Epub 2014 Aug 28.

Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, Unites States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105340PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148240PMC
October 2015

Developmental stage-dependent impact of midazolam on calbindin, calretinin and parvalbumin expression in the immature rat medial prefrontal cortex during the brain growth spurt.

Int J Dev Neurosci 2015 Oct 18;45:19-28. Epub 2015 Apr 18.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Switzerland; Department of Fundamental Neurosciences, University of Geneva Medical School, Geneva, Switzerland; Geneva Neuroscience Center, University of Geneva, Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijdevneu.2015.04.002DOI Listing
October 2015

Systemic physiology and neuroapoptotic profiles in young and adult rats exposed to surgery: A randomized controlled study comprising four different anaesthetic techniques.

Int J Dev Neurosci 2015 Oct 24;45:11-8. Epub 2015 Apr 24.

Department of Plastic Surgery, Odense University Hospital, Sdr. Boulevard 29, Odense 5000, Denmark; Institute of Clinical Research, University of Southern Denmark, Winsløvparken 19, Odense 5000 Denmark.

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http://dx.doi.org/10.1016/j.ijdevneu.2015.04.351DOI Listing
October 2015

Imaging the progression of anesthetic-induced neurotoxicity: a leap toward translational relevance.

Anesthesiology 2015 Sep;123(3):497-8

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland (L.V.); and Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts (S.G.S.).

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ALN.0000000000000763DOI Listing
September 2015

Staying away from the edge - cerebral oximetry guiding blood pressure management.

Paediatr Anaesth 2015 Jul;25(7):654-5

Department of Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1111/pan.12698DOI Listing
July 2015

Safe Anesthesia For Every Tot - The SAFETOTS initiative.

Curr Opin Anaesthesiol 2015 Jun;28(3):302-7

aFaculty of Medicine, University of Zurich bDepartment of Anaesthesia, University Children's Hospital Zurich, Zurich, Switzerland cDepartment of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva dDepartment of Anaesthesia & Intensive Care, Paediatric Section, Odense University Hospital eClinical Institute - Anaesthesiology, University of Southern Denmark, Odense, Denmark fSchool of Medicine and Dentistry, University of Aberdeen, Royal Aberdeen Children's Hospital, Scotland, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ACO.0000000000000186DOI Listing
June 2015

Impact of propofol anaesthesia on cytokine expression profiles in the developing rat brain: a randomised placebo-controlled experimental in-vivo study.

Eur J Anaesthesiol 2015 May;32(5):336-45

From the Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva (PK, J-CC, LV), Department of Fundamental Neuroscience (PK, LV), Geneva Neuroscience Center, University of Geneva Medical School (LV), Division of Cardiology, Foundation for Medical Researches, Department of Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland (SL, FM, FM, J-CC), Department of Internal Medicine, University of Genoa School of Medicine, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy (FM), Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, Geneva, Switzerland (FM).

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http://pdfs.journals.lww.com/ejanaesthesiology/2015/05000/Im
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http://dx.doi.org/10.1097/EJA.0000000000000128DOI Listing
May 2015

Anesthesia and the developing brain: a way forward for clinical research.

Paediatr Anaesth 2015 May 27;25(5):447-52. Epub 2015 Mar 27.

Anaesthesia and Pain Management Research Group, Murdoch Childrens Research Institute, Melbourne, Vic., Australia; Department of Anaesthesia and Pain Management, The Royal Children's Hospital, Melbourne, Vic., Australia; Department of Paediatrics, University of Melbourne, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/pan.12652DOI Listing
May 2015

General anesthetics in brain injury: friends or foes?

Authors:
Laszlo Vutskits

Curr Pharm Des 2014 ;20(26):4203-10

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, 4, rue Gabrielle-Perret-Gentil, 1211 Geneva 4, Switzerland.

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March 2015

Pushing the standards forward: in-depth monitoring of physiological parameters in anesthetized neonatal mice.

Anesth Analg 2014 Nov;119(5):1029-31

From the *Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Geneva, Switzerland; and †Department of Anesthesiology, University of California San Diego School of Medicine, San Diego, California.

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http://dx.doi.org/10.1213/ANE.0000000000000440DOI Listing
November 2014

Cerebral blood flow in the neonate.

Authors:
Laszlo Vutskits

Paediatr Anaesth 2014 Jan 15;24(1):22-9. Epub 2013 Nov 15.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland; Department of Fundamental Neuroscience, Geneva University Medical School, Geneva, Switzerland.

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http://dx.doi.org/10.1111/pan.12307DOI Listing
January 2014

Bronchial rupture after sled trauma in a 13-year-old boy.

Ann Thorac Surg 2014 Jan;97(1):345

Geneva's University Hospital, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.athoracsur.2013.04.087DOI Listing
January 2014

Propofol anesthesia impairs the maturation and survival of adult-born hippocampal neurons.

Anesthesiology 2013 Mar;118(3):602-10

Department of Fundamental Neurosciences, University of Lausanne, Switzerland.

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http://dx.doi.org/10.1097/ALN.0b013e3182815948DOI Listing
March 2013

An ion transport-independent role for the cation-chloride cotransporter KCC2 in dendritic spinogenesis in vivo.

Cereb Cortex 2013 Feb 17;23(2):378-88. Epub 2012 Feb 17.

Center for Psychiatric Neurosciences, Department of Psychiatry, Lausanne University Hospital, 1008 Prilly-Lausanne, Switzerland.

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http://dx.doi.org/10.1093/cercor/bhs027DOI Listing
February 2013

Effects of morphine on the differentiation and survival of developing pyramidal neurons during the brain growth spurt.

Toxicol Sci 2012 Nov 27;130(1):168-79. Epub 2012 Jul 27.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, 1211 Geneva, Switzerland.

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https://academic.oup.com/toxsci/article/1667766/Effects
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http://dx.doi.org/10.1093/toxsci/kfs234DOI Listing
November 2012

General anesthesia: a gateway to modulate synapse formation and neural plasticity?

Authors:
Laszlo Vutskits

Anesth Analg 2012 Nov 2;115(5):1174-82. Epub 2012 Aug 2.

Department of Anesthesiology, Pharmacology, and Intensive Care, University Hospital of Geneva, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1213/ANE.0b013e31826a1178DOI Listing
November 2012

Alpha2-adrenergic receptor activation regulates cortical interneuron migration.

Eur J Neurosci 2012 Oct 17;36(7):2879-87. Epub 2012 Jul 17.

Department of Mental Health and Psychiatry, University of Geneva Medical School, Geneva, Switzerland.

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http://dx.doi.org/10.1111/j.1460-9568.2012.08231.xDOI Listing
October 2012

Anesthetics and the developing brain: time for a change in practice? A pro/con debate.

Paediatr Anaesth 2012 Oct;22(10):973-80

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/pan.12015DOI Listing
October 2012

Use of therapeutic surfactant lavage in a preterm infant with massive pulmonary hemorrhage.

Clin Pract 2012 May 6;2(3):e74. Epub 2012 Aug 6.

Pediatric and Neonatal Intensive Care Unit, Department of Pediatrics;

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http://dx.doi.org/10.4081/cp.2012.e74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981312PMC
May 2012

Anesthetic-related neurotoxicity and the developing brain: shall we change practice?

Authors:
Laszlo Vutskits

Paediatr Drugs 2012 Feb;14(1):13-21

Pediatric Anesthesia Unit, Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.2165/11592840-000000000-00000DOI Listing
February 2012

Early postnatal migration and development of layer II pyramidal neurons in the rodent cingulate/retrosplenial cortex.

Cereb Cortex 2012 Jan 30;22(1):144-57. Epub 2011 May 30.

Department of Neurosciences, University of Geneva Medical School, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1093/cercor/bhr097DOI Listing
January 2012

Developmental Stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex.

Anesthesiology 2011 Aug;115(2):282-93

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1097/ALN.0b013e318221fbbdDOI Listing
August 2011

Bilateral whisker trimming during early postnatal life impairs dendritic spine development in the mouse somatosensory barrel cortex.

J Comp Neurol 2010 May;518(10):1711-23

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1002/cne.22297DOI Listing
May 2010

The role of PSA-NCAM in adult neurogenesis.

Adv Exp Med Biol 2010 ;663:127-36

Developmental Biology Institute of Marseilles-Luminy (IBDML), Case 907, Parc Scientifique de Luminy, 13288 Marseille Cedex 9, France.

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http://dx.doi.org/10.1007/978-1-4419-1170-4_8DOI Listing
March 2010

Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis.

Anesthesiology 2010 Mar;112(3):546-56

Department of Anesthesiology, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1097/ALN.0b013e3181cd7942DOI Listing
March 2010

Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data.

Pediatr Res 2010 Feb;67(2):117-27

Neonatal Intensive Care Unit, Centre Hospitalier Intercommunal de Créteil, Créteil 94000, France.

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http://dx.doi.org/10.1203/PDR.0b013e3181c8eef3DOI Listing
February 2010

A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage.

Intensive Care Med 2010 Jan 17;36(1):107-15. Epub 2009 Sep 17.

Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, DBSB/CMU, Rue Michel Servet, 1, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1007/s00134-009-1641-yDOI Listing
January 2010

[Does anesthesia affect cerebral development].

Presse Med 2009 Nov 24;38(11):1591-6. Epub 2009 Sep 24.

Unité d'anesthésie pédiatrique, Département d'anesthésiologie, pharmacologie et soins intensifs, Hôpitaux Universitaires de Genève, 1205 Genève, Suisse.

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http://dx.doi.org/10.1016/j.lpm.2009.07.013DOI Listing
November 2009

Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial.

Neurochem Res 2008 Jul 13;33(7):1325-31. Epub 2008 Feb 13.

Division of Anesthesiology, University Hospitals of Geneva, 24, rue Micheli-du-Crest, CH-1211, Geneva 14, Switzerland.

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http://link.springer.com/10.1007/s11064-007-9586-4
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http://dx.doi.org/10.1007/s11064-007-9586-4DOI Listing
July 2008

Adverse effects of methylene blue on the central nervous system.

Anesthesiology 2008 Apr;108(4):684-92

Division of Anesthesiology, University Hospitals of Geneva, and Department of Neuroscience, Faculty of Medicine, Geneva University, Geneva, Switzerland.

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http://dx.doi.org/10.1097/ALN.0b013e3181684be4DOI Listing
April 2008

Polysialic acid-neural cell adhesion molecule in brain plasticity: from synapses to integration of new neurons.

Brain Res Rev 2007 Nov 4;56(1):101-18. Epub 2007 Jul 4.

Department of Neuroscience, University of Geneva Medical School, 1, Rue Michel Servet, CH-1211, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.brainresrev.2007.05.014DOI Listing
November 2007

Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture.

Toxicology 2007 May 12;234(3):216-26. Epub 2007 Mar 12.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.

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http://dx.doi.org/10.1016/j.tox.2007.03.004DOI Listing
May 2007

PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival.

Development 2007 Mar 14;134(6):1181-90. Epub 2007 Feb 14.

Department of Neuroscience, University of Geneva Medical School, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1242/dev.02808DOI Listing
March 2007

Effects of ketamine on the developing central nervous system.

Ideggyogy Sz 2007 Mar;60(3-4):109-12

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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March 2007

A role for atm in E-cadherin-mediated contact inhibition in epithelial cells.

Breast Cancer Res Treat 2006 Sep 16;99(2):143-53. Epub 2006 Mar 16.

Division of Oncology, Geneva Medical School, Geneva 4, Switzerland.

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http://dx.doi.org/10.1007/s10549-006-9195-yDOI Listing
September 2006

Effect of ketamine on dendritic arbor development and survival of immature GABAergic neurons in vitro.

Toxicol Sci 2006 Jun 31;91(2):540-9. Epub 2006 Mar 31.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, 1211 Geneva 14, Switzerland.

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http://dx.doi.org/10.1093/toxsci/kfj180DOI Listing
June 2006

The polysialylated neural cell adhesion molecule promotes neurogenesis in vitro.

Neurochem Res 2006 Feb 30;31(2):215-25. Epub 2006 Mar 30.

Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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February 2006

Anesthesia management in a young child with aromatic l-amino acid decarboxylase deficiency.

Paediatr Anaesth 2006 Jan;16(1):82-4

Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/j.1460-9592.2005.01605.xDOI Listing
January 2006

Clinically relevant concentrations of propofol but not midazolam alter in vitro dendritic development of isolated gamma-aminobutyric acid-positive interneurons.

Anesthesiology 2005 May;102(5):970-6

Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital of Geneva, Switzerland.

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http://dx.doi.org/10.1097/00000542-200505000-00016DOI Listing
May 2005

VEGF is a chemoattractant for FGF-2-stimulated neural progenitors.

J Cell Biol 2003 Dec;163(6):1375-84

Department of Morphology, University Medical Center, University of Geneva Medical School, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200308040
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173724PMC
December 2003

Acute differential modulation of synaptic transmission and cell survival during exposure to pulsed and continuous radiofrequency energy.

J Pain 2003 May;4(4):197-202

Interventional Pain Program, Department of Anesthesiology, Geneva University Hospital, Geneva, Switzerland.

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http://dx.doi.org/10.1016/s1526-5900(03)00554-6DOI Listing
May 2003

Neuronal-induced and glutamate-dependent activation of glial glutamate transporter function.

J Neurochem 2002 Aug;82(4):987-97

Department of Physiology, University of Geneva Medical School (CMU), Geneva, Switzerland.

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http://dx.doi.org/10.1046/j.1471-4159.2002.01075.xDOI Listing
August 2002

Topographic microsurgical anatomy of the paraclinoid carotid artery.

Neurosurg Rev 2002 Jun;25(3):177-83

Department of Neurosurgery, Johannes Gutenberg University, Mainz, Germany.

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http://link.springer.com/content/pdf/10.1007/s10143-001-0192
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June 2002