Publications by authors named "Laszlo Virág"

100Publications

Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes.

Front Pharmacol 2020 22;11:1116. Epub 2020 Jul 22.

Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.3389/fphar.2020.01116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391956PMC
July 2020

Different effect of amiodarone and dofetilide on the dispersion of repolarization between well coupled ventricular and Purkinje fibers.

Can J Physiol Pharmacol 2020 Jul 21. Epub 2020 Jul 21.

University of Szeged, Department of Pharmacology and Pharmacotherapy , Dom ter 12 , Szeged, Hungary , 6720.

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http://dx.doi.org/10.1139/cjpp-2020-0234DOI Listing
July 2020

How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington's Disease? A Comprehensive Review.

Int J Mol Sci 2020 Jun 16;21(12). Epub 2020 Jun 16.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.

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http://dx.doi.org/10.3390/ijms21124282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349273PMC
June 2020

Late sodium current in human, canine and guinea pig ventricular myocardium.

J Mol Cell Cardiol 2020 02 17;139:14-23. Epub 2020 Jan 17.

Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Dental Physiology and Pharmacology, Faculty of Dentistry, University of Debrecen, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.12.015DOI Listing
February 2020

Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis.

Exp Dermatol 2020 01 6;29(1):79-85. Epub 2019 Dec 6.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1111/exd.14061DOI Listing
January 2020

Implication of frequency-dependent protocols in antiarrhythmic and proarrhythmic drug testing.

Prog Biophys Mol Biol 2020 Nov 11;157:76-83. Epub 2019 Nov 11.

Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary; Department of Pharmacology and Pharmacotherapy, Interdisciplinary Excellence Centre, University of Szeged, Szeged, Hungary; MTA-SZTE Research Group for Cardiovascular Pharmacology, Szeged, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2019.11.001DOI Listing
November 2020

Self-defense of macrophages against oxidative injury: Fighting for their own survival.

Redox Biol 2019 09 28;26:101261. Epub 2019 Jun 28.

Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM). Arturo Duperier 4, 28029, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), ISCIII, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614175PMC
September 2019

Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos.

Redox Biol 2019 09 9;26:101239. Epub 2019 Jun 9.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582207PMC
September 2019

PARP1-LSD1 functional interplay controls transcription of SOD2 that protects human pro-inflammatory macrophages from death under an oxidative condition.

Free Radic Biol Med 2019 02 6;131:218-224. Epub 2018 Dec 6.

Department of General Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.12.004DOI Listing
February 2019

Administration of the benzodiazepine midazolam increases tau phosphorylation in the mouse brain.

Neurobiol Aging 2019 03 8;75:11-24. Epub 2018 Nov 8.

Département de Psychiatrie et Neurosciences, Faculté de Médecine, Université Laval, Québec City, Québec, Canada; CRCHU, CHUL, Neurosciences, Québec City, Québec, Canada.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349516PMC
March 2019

LPS protects macrophages from AIF-independent parthanatos by downregulation of PARP1 expression, induction of SOD2 expression, and a metabolic shift to aerobic glycolysis.

Free Radic Biol Med 2019 02 28;131:184-196. Epub 2018 Nov 28.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary; Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/143, 90-236 Łódź, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08915849183156
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http://dx.doi.org/10.1016/j.freeradbiomed.2018.11.034DOI Listing
February 2019

PARP1 promoter links cell cycle progression with adaptation to oxidative environment.

Redox Biol 2018 09 2;18:1-5. Epub 2018 Jun 2.

Department of General Biophysics, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2018.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991907PMC
September 2018

Redox control of cancer cell destruction.

Redox Biol 2018 06 3;16:59-74. Epub 2018 Feb 3.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842284PMC
June 2018

Diverse effect of BMP-2 homodimer on mesenchymal progenitors of different origin.

Hum Cell 2018 Apr 13;31(2):139-148. Epub 2018 Feb 13.

Faculty of Dentistry, University of Debrecen, Nagyerdei krt. 98, Debrecen, 4012, Hungary.

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http://dx.doi.org/10.1007/s13577-018-0202-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852203PMC
April 2018

PARP1 facilitates EP300 recruitment to the promoters of the subset of RBL2-dependent genes.

Biochim Biophys Acta Gene Regul Mech 2017 Dec 4. Epub 2017 Dec 4.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary.

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http://dx.doi.org/10.1016/j.bbagrm.2017.12.001DOI Listing
December 2017

Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair.

Redox Biol 2018 05 29;15:316-326. Epub 2017 Dec 29.

Department of General Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317173089
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http://dx.doi.org/10.1016/j.redox.2017.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975074PMC
May 2018

Comparison of the effects of I, I, and I block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae.

Can J Physiol Pharmacol 2018 Jan 11;96(1):18-25. Epub 2017 Sep 11.

a Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1139/cjpp-2017-0342DOI Listing
January 2018

Different electrophysiological effects of the levo- and dextro-rotatory isomers of mexiletine in isolated rabbit cardiac muscle.

Can J Physiol Pharmacol 2017 Jul 22;95(7):830-836. Epub 2017 Feb 22.

a Department of Pharmacology & Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1139/cjpp-2016-0599DOI Listing
July 2017

Diabetes-induced oxidative stress in the vitreous humor.

Redox Biol 2016 10 8;9:100-103. Epub 2016 Jul 8.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961280PMC
October 2016

The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism.

Mutat Res 2016 08 5;790:31-40. Epub 2016 Jul 5.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.mrfmmm.2016.07.001DOI Listing
August 2016

Rabbit models as tools for preclinical cardiac electrophysiological safety testing: Importance of repolarization reserve.

Prog Biophys Mol Biol 2016 07 18;121(2):157-68. Epub 2016 May 18.

Department of Pharmacology & Pharmacotherapy, University of Szeged, Dóm tér 12., 6720 Szeged, Hungary; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Dóm tér 12., 6720 Szeged, Hungary.

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http://dx.doi.org/10.1016/j.pbiomolbio.2016.05.002DOI Listing
July 2016

Mitochondrial poly(ADP-ribose) polymerase: The Wizard of Oz at work.

Free Radic Biol Med 2016 11 8;100:257-270. Epub 2016 Mar 8.

Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA; Shriners Hospital for Children, Galveston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016203PMC
November 2016

High Throughput Screening Identifies a Novel Compound Protecting Cardiomyocytes from Doxorubicin-Induced Damage.

Oxid Med Cell Longev 2015 7;2015:178513. Epub 2015 Jun 7.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen 4032, Hungary ; MTA-DE Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Debrecen 4032, Hungary.

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http://dx.doi.org/10.1155/2015/178513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475553PMC
April 2016

Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.

Neurobiol Aging 2015 Aug 9;36(8):2414-28. Epub 2015 May 9.

Département de Psychiatrie et Neurosciences, Faculté de Médecine, Université Laval, Québec, Québec, Canada; Neurosciences, CHUL, CRCHU, Québec, Québec, Canada.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465078PMC
August 2015

Poly(ADP-ribose) in the bone: from oxidative stress signal to structural element.

Free Radic Biol Med 2015 May 4;82:179-86. Epub 2015 Feb 4.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2015.01.027DOI Listing
May 2015

Effects of Chelidonium majus extracts and major alkaloids on hERG potassium channels and on dog cardiac action potential - a safety approach.

Fitoterapia 2015 Jan 4;100:156-65. Epub 2014 Dec 4.

Department of Pharmacognosy, University of Szeged, Faculty of Pharmacy, Eötvös u. 6, H-6720 Szeged, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2014.11.023DOI Listing
January 2015

Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress.

Redox Biol 2014 21;2:978-82. Epub 2014 Aug 21.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Nagyerdei Krt. 98., H-4032 Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2014.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215470PMC
January 2018

Protein phosphatase-1 is involved in the maintenance of normal homeostasis and in UVA irradiation-induced pathological alterations in HaCaT cells and in mouse skin.

Biochim Biophys Acta 2015 Jan 8;1852(1):22-33. Epub 2014 Nov 8.

Department of Medical Chemistry, University of Debrecen, Debrecen H-4032, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.11.005DOI Listing
January 2015

The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway.

Free Radic Biol Med 2014 Nov 29;76:69-79. Epub 2014 Jul 29.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.07.027DOI Listing
November 2014

Activation of poly(ADP-ribose) polymerase-1 delays wound healing by regulating keratinocyte migration and production of inflammatory mediators.

Mol Med 2014 Aug 26;20:363-71. Epub 2014 Aug 26.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary.

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http://dx.doi.org/10.2119/molmed.2014.00130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153841PMC
August 2014

Deletion of PARP-2 induces hepatic cholesterol accumulation and decrease in HDL levels.

Biochim Biophys Acta 2014 Apr 21;1842(4):594-602. Epub 2013 Dec 21.

MTA-DE Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, 4032 Debrecen, Hungary; Department of Medical Chemistry, University of Debrecen, 4032 Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2013.12.006DOI Listing
April 2014

Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages.

J Leukoc Biol 2013 Dec 6;94(6):1309-15. Epub 2013 Aug 6.

1.Rutgers New Jersey Medical School, 185 South Orange Ave., University Heights, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1189/jlb.0113043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828607PMC
December 2013

Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1.

PLoS One 2013 24;8(7):e70333. Epub 2013 Jul 24.

Department of Pulmonary Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070333PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722143PMC
February 2014

L-364,373 (R-L3) enantiomers have opposite modulating effects on IKs in mammalian ventricular myocytes.

Can J Physiol Pharmacol 2013 Aug 8;91(8):586-92. Epub 2013 Jan 8.

Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, H-6701 Szeged, Hungary.

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http://dx.doi.org/10.1139/cjpp-2012-0407DOI Listing
August 2013

50Years of poly(ADP-ribosyl)ation.

Authors:
László Virág

Mol Aspects Med 2013 Dec 28;34(6):1043-5. Epub 2013 May 28.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary; MTA DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2013.05.002DOI Listing
December 2013

Role of poly(ADP-ribosyl)ation in a 'two-hit' model of hypoxia and oxidative stress in human A549 epithelial cells in vitro.

Int J Mol Med 2013 Aug 29;32(2):339-46. Epub 2013 May 29.

Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX 77555-1102, USA.

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http://dx.doi.org/10.3892/ijmm.2013.1397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776717PMC
August 2013

Cytoprotective dibenzoylmethane derivatives protect cells from oxidative stress-induced necrotic cell death.

Pharmacol Res 2013 Jun 21;72:25-34. Epub 2013 Mar 21.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1016/j.phrs.2013.03.002DOI Listing
June 2013

Poly(ADP-ribose) signaling in cell death.

Mol Aspects Med 2013 Dec 15;34(6):1153-67. Epub 2013 Feb 15.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary; MTA DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2013.01.007DOI Listing
December 2013

Poly(ADP-ribose): PARadigms and PARadoxes.

Mol Aspects Med 2013 Dec 2;34(6):1046-65. Epub 2013 Jan 2.

Department of Biology, University of Konstanz, Konstanz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2012.12.010DOI Listing
December 2013

3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism.

Biochim Biophys Acta 2013 Mar 12;1833(3):743-51. Epub 2012 Dec 12.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1016/j.bbamcr.2012.12.003DOI Listing
March 2013

Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone.

Am J Physiol Lung Cell Mol Physiol 2013 Feb 30;304(3):L191-7. Epub 2012 Nov 30.

Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, 622 W. 168 St., P&S Box 46, New York, NY 10032, USA.

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http://dx.doi.org/10.1152/ajplung.00274.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567364PMC
February 2013

Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes.

FEBS Lett 2012 Nov 26;586(21):3771-7. Epub 2012 Sep 26.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen H-4032, Hungary.

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http://dx.doi.org/10.1016/j.febslet.2012.09.026DOI Listing
November 2012

Poly(ADP-ribosyl)ation is a survival mechanism in cigarette smoke-induced and hydrogen peroxide-mediated cell death.

Free Radic Biol Med 2012 Nov 27;53(9):1680-8. Epub 2012 Aug 27.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.08.579DOI Listing
November 2012

Hydrogen peroxide-induced poly(ADP-ribosyl)ation regulates osteogenic differentiation-associated cell death.

Free Radic Biol Med 2012 Oct 20;53(8):1552-64. Epub 2012 Aug 20.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, H-4032 Debrecen, Hungary.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.08.567DOI Listing
October 2012

Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein.

Cell Mol Life Sci 2012 Dec 13;69(24):4079-92. Epub 2012 May 13.

Medical and Health Science Center, MHSC, Department of Medical Chemistry, University of Debrecen, Nagyerdei krt. 98., Pf. 7, 4032 Debrecen, Hungary.

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http://dx.doi.org/10.1007/s00018-012-1003-8DOI Listing
December 2012

Poly(ADP-ribose) in the skin and in melanomas.

Histol Histopathol 2012 05;27(5):651-9

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.14670/HH-27.651DOI Listing
May 2012

Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process.

J Immunol 2012 Jan 23;188(1):445-53. Epub 2011 Nov 23.

Department of Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA.

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http://dx.doi.org/10.4049/jimmunol.1101224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384725PMC
January 2012

Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction.

Cardiovasc Res 2011 Dec 15;92(3):430-8. Epub 2011 Sep 15.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, Nagyerdei krt 98. Pf. 7, H-4032 Debrecen, Hungary.

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http://dx.doi.org/10.1093/cvr/cvr246DOI Listing
December 2011

Ecto-5'-nucleotidase (CD73) decreases mortality and organ injury in sepsis.

J Immunol 2011 Oct 14;187(8):4256-67. Epub 2011 Sep 14.

Department of Surgery, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103, USA.

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http://dx.doi.org/10.4049/jimmunol.1003379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387540PMC
October 2011

Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation.

PLoS Comput Biol 2011 May 26;7(5):e1002061. Epub 2011 May 26.

Cardiac Bioelectricity and Arrhythmia Center, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1002061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102752PMC
May 2011

Propofol directly increases tau phosphorylation.

PLoS One 2011 Jan 31;6(1):e16648. Epub 2011 Jan 31.

Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016648PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031597PMC
January 2011

Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress.

J Invest Dermatol 2010 Nov 8;130(11):2629-37. Epub 2010 Jul 8.

Department of Medical Chemistry, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary.

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http://dx.doi.org/10.1038/jid.2010.190DOI Listing
November 2010

The differential effects of equipotent doses of isoflurane and desflurane on hippocampal acetylcholine levels in young and aged rats.

Neurosci Lett 2010 Mar 25;471(3):166-70. Epub 2010 Jan 25.

Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, 622 West 168th Street PH 5, New York, NY 10032, United States.

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http://dx.doi.org/10.1016/j.neulet.2010.01.034DOI Listing
March 2010

Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells.

FASEB J 2009 Oct 1;23(10):3553-63. Epub 2009 Jul 1.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, H-4032 Debrecen, Hungary.

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http://dx.doi.org/10.1096/fj.09-133264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747681PMC
October 2009

Reverse rate dependency is an intrinsic property of canine cardiac preparations.

Cardiovasc Res 2009 Nov 25;84(2):237-44. Epub 2009 Jun 25.

Department of Physiology, University of Debrecen, Nagyerdei krt 98, PO Box: 22, H-4012 Debrecen, Hungary.

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http://dx.doi.org/10.1093/cvr/cvp213DOI Listing
November 2009

Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.

Anesthesiology 2009 Apr;110(4):748-58

Department of Anesthesiology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608685PMC
http://dx.doi.org/10.1097/aln.0b013e31819c44e1DOI Listing
April 2009

5,7,8-Trimethyl-benzopyran and 5,7,8-trimethyl-1,4-benzoxazine aminoamide derivatives as novel antiarrhythmics against ischemia-reperfusion injury.

J Med Chem 2009 Apr;52(8):2328-40

Institute of Organic and Pharmaceutical Chemistry, National Hellenic Research Foundation, 48 Vas. Constantinou Avenue, 116 35 Athens, Greece.

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http://dx.doi.org/10.1021/jm801228hDOI Listing
April 2009

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia.

FASEB J 2009 Aug 11;23(8):2595-604. Epub 2009 Mar 11.

Axe Neurosciences, Centre Hospitalier de l'Université Laval, Université Laval, Québec, Québec, Canada.

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http://dx.doi.org/10.1096/fj.08-122424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717763PMC
August 2009

Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly(ADP-ribose) polymerase-1.

FEBS Lett 2008 May 24;582(12):1672-8. Epub 2008 Apr 24.

Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, H-4012 Debrecen, Nagyerdei krt. 98, Hungary.

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http://dx.doi.org/10.1016/j.febslet.2008.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713039PMC
May 2008