Laszlo Tora

Laszlo Tora

UNVERIFIED PROFILE

Are you Laszlo Tora?   Register this Author

Register author
Laszlo Tora

Laszlo Tora

Publications by authors named "Laszlo Tora"

Are you Laszlo Tora?   Register this Author

100Publications

1562Reads

45Profile Views

Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress.

Cancers (Basel) 2019 Mar 13;11(3). Epub 2019 Mar 13.

Biotechnologie et Signalisation Cellulaire, UMR 7242, CNRS/Université de Strasbourg, Boulevard S. Brant, 67412 Illlkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11030355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468890PMC
March 2019

Global role for coactivator complexes in RNA polymerase II transcription.

Transcription 2019 02 9;10(1):29-36. Epub 2018 Oct 9.

a Institut de Génétique et de Biologie Moléculaire et Cellulaire , Illkirch , France.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/21541264.2018.1
Publisher Site
http://dx.doi.org/10.1080/21541264.2018.1521214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351120PMC
February 2019

Visualization of Endogenous Transcription Factors in Single Cells Using an Antibody Electroporation-Based Imaging Approach.

Methods Mol Biol 2019 ;2038:209-221

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9674-2_14DOI Listing
January 2019

Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.

Nat Struct Mol Biol 2018 12 3;25(12):1119-1127. Epub 2018 Dec 3.

Bristol Synthetic Biology Centre BrisSynBio, Biomedical Sciences, School of Biochemistry, University of Bristol, Bristol, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41594-018-0156-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292499PMC
December 2018

Transcript Buffering: A Balancing Act between mRNA Synthesis and mRNA Degradation.

Mol Cell 2018 10;72(1):10-17

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UMR7104, INSERM U1258 and Université de Strasbourg, 67404 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10972765183068
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2018.08.023DOI Listing
October 2018

Sharing the SAGA.

Trends Biochem Sci 2017 11 27;42(11):850-861. Epub 2017 Sep 27.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, 67404 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibs.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660625PMC
November 2017

The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.

Development 2017 10 11;144(20):3808-3818. Epub 2017 Sep 11.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch 67400, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.146902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650055PMC
October 2017

Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID.

Mol Cell 2017 Oct 14;68(1):118-129.e5. Epub 2017 Sep 14.

Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679267PMC
October 2017

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Mol Cell 2017 Oct 14;68(1):130-143.e5. Epub 2017 Sep 14.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, 67404 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10972765173061
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2017.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632562PMC
October 2017

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.

Nat Commun 2017 10 20;8(1):1088. Epub 2017 Oct 20.

Department of Epigenetics and Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-017-01173-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651844PMC
October 2017

Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription.

EMBO J 2017 09 19;36(18):2710-2725. Epub 2017 Jul 19.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201696035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599802PMC
September 2017

KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number.

Mol Cell Oncol 2017 16;4(2):e1270391. Epub 2016 Dec 16.

Development and Stem Cell Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/23723556.2016.1270391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383365PMC
December 2016

Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells.

Exp Cell Res 2016 Mar 9;342(2):145-58. Epub 2016 Mar 9.

Ecole Supérieure de Biotechnologie de Strasbourg, UMR 7242, CNRS/Université de Strasbourg, boulevard Sébastien Brant, 67412 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2016.03.003DOI Listing
March 2016

TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.

Elife 2016 Feb 25;5. Epub 2016 Feb 25.

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.12534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775216PMC
February 2016

Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells.

Epigenetics Chromatin 2015 6;8:45. Epub 2015 Nov 6.

Cellular Signalling and Nuclear Dynamics Programme, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U964, Université de Strasbourg (UdS), BP 10142, 1 Rue Laurent Fries, CU de Strasbourg, 67404 Illkirch Cedex, France.

View Article

Download full-text PDF

Source
http://www.epigeneticsandchromatin.com/content/8/1/45
Publisher Site
http://dx.doi.org/10.1186/s13072-015-0039-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636812PMC
November 2015

TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.

Mol Cell Biol 2015 Jun 13;35(12):2103-18. Epub 2015 Apr 13.

Cellular Signaling and Nuclear Dynamics Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), UMR 7104 CNRS, INSERM U964, Université de Strasbourg, Illkirch, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01370-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438247PMC
June 2015

Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.

Nat Commun 2015 Jan 14;6:6011. Epub 2015 Jan 14.

1] European Molecular Biology Laboratory, Grenoble Outstation, 6 rue Jules Horowitz, 38042 Grenoble, France [2] Unit for Virus Host-Cell Interactions, University Grenoble Alpes-EMBL-CNRS, 6 rue Jules Horowitz, 38042 Grenoble, France [3] School of Biochemistry, Bristol University, Bristol BS8 1TD, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ncomms7011
Publisher Site
http://dx.doi.org/10.1038/ncomms7011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309443PMC
January 2015

Interpreting and visualizing ChIP-seq data with the seqMINER software.

Methods Mol Biol 2014 ;1150:141-52

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), UMR 7104 CNRS, UdS, INSERM U964, BP 10142, F-67404 ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-0512-6_8DOI Listing
November 2014

The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription.

Genes Dev 2014 Sep;28(18):1999-2012

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; UMR7104, Centre National de la Recherche Scientifique, 67404 Illkirch, France; U964, Institut National de la Santé et de la Recherche Médicale, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, Cedex, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.250225.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173158PMC
September 2014

UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells.

PLoS Genet 2014 Jul 24;10(7):e1004483. Epub 2014 Jul 24.

Cellular signaling and nuclear dynamics program, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pgen.1004483
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1004483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109906PMC
July 2014

Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation.

Elife 2014 Jun 4;3. Epub 2014 Jun 4.

Cellular signaling and nuclear dynamics program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - Inserm U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.02104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059888PMC
June 2014

Histone H2B ubiquitination: signaling not scrapping.

Drug Discov Today Technol 2014 Jun;12:e19-27

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, France. Electronic

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ddtec.2012.09.002DOI Listing
June 2014

Chromatin and DNA sequences in defining promoters for transcription initiation.

Biochim Biophys Acta 2014 Mar 22;1839(3):118-28. Epub 2013 Nov 22.

Cellular Signaling and Nuclear Dynamics Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), UMR 7104 CNRS, UdS, INSERM U964, BP 10142, F-67404 Illkirch Cedex, CU de Strasbourg, France; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2013.11.003DOI Listing
March 2014

How to stop: the mysterious links among RNA polymerase II occupancy 3' of genes, mRNA 3' processing and termination.

Transcription 2013 Jan-Feb;4(1):7-12. Epub 2012 Nov 6.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/trns.22300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644043PMC
July 2013

The human TREX-2 complex is stably associated with the nuclear pore basket.

J Cell Sci 2013 Jun 16;126(Pt 12):2656-67. Epub 2013 Apr 16.

Cellular Signaling and Nuclear Dynamics Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U964, Université de Strasbourg, BP 10142 - 67404 ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.118000DOI Listing
June 2013

Transcription-replication encounters, consequences and genomic instability.

Nat Struct Mol Biol 2013 Apr;20(4):412-8

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.2543DOI Listing
April 2013

The architecture of human general transcription factor TFIID core complex.

Nature 2013 Jan 6;493(7434):699-702. Epub 2013 Jan 6.

European Molecular Biology Laboratory Grenoble Outstation, Unit of Virus Host Cell Interactions UVHCI, UJF-CNRS-EMBL Unité Mixte International UMI 3265, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France.

View Article

Download full-text PDF

Source
http://www.4dcellfate.eu/sites/default/files/article-files/n
Web Search
http://www.nature.com/doifinder/10.1038/nature11791
Publisher Site
http://dx.doi.org/10.1038/nature11791DOI Listing
January 2013

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.

PLoS One 2012 11;7(6):e38769. Epub 2012 Jun 11.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038769PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372504PMC
November 2012

TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.

J Biol Chem 2012 Aug 13;287(33):27580-92. Epub 2012 Jun 13.

Département de Biologie Intégrative, Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UDS), CNRS, INSERM, 1 rue Laurent Fries, B.P. 10142, 67404 Illkirch Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M112.379206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431708PMC
August 2012

H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells.

BMC Genomics 2012 Aug 24;13:424. Epub 2012 Aug 24.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, BP 10142-67404 ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
Publisher Site
http://dx.doi.org/10.1186/1471-2164-13-424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473242PMC
August 2012

A fraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex.

Biochim Biophys Acta 2011 Dec 12;1814(12):1812-24. Epub 2011 Oct 12.

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S157096391100264
Publisher Site
http://dx.doi.org/10.1016/j.bbapap.2011.09.008DOI Listing
December 2011

Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes.

Mol Cell 2011 Dec;44(6):966-77

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, BP 10142-67404 ILLKIRCH Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2011.10.013DOI Listing
December 2011

SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers.

Mol Cell 2011 Nov;44(3):410-423

Program of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U964, Université de Strasbourg, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S109727651100789
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2011.08.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641564PMC
November 2011

The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements.

Mol Cell Biol 2011 Sep 11;31(18):3734-44. Epub 2011 Jul 11.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.05231-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165722PMC
September 2011

TBP2 is a general transcription factor specialized for female germ cells.

J Biol 2009 30;8(11):97. Epub 2009 Nov 30.

Department of Medical and Molecular Genetics, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/jbiol196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804282PMC
March 2011

seqMINER: an integrated ChIP-seq data interpretation platform.

Nucleic Acids Res 2011 Mar 21;39(6):e35. Epub 2010 Dec 21.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 596, Université de Strasbourg, BP 10142-67404 ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkq1287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064796PMC
March 2011

Developmental regulation of transcription initiation: more than just changing the actors.

Curr Opin Genet Dev 2010 Oct 2;20(5):533-40. Epub 2010 Jul 2.

Department of Medical and Molecular Genetics, Division of Reproductive and Child Health, Institute of Biomedical Research, University of Birmingham, B15 2TT Edgbaston, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2010.06.004DOI Listing
October 2010

Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases.

Epigenetics Chromatin 2010 Oct 20;3(1):18. Epub 2010 Oct 20.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, 1 Rue Laurent Fries, 67404 Illkirch Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8935-3-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972259PMC
October 2010

Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3.

Nat Cell Biol 2010 Sep 1;12(9):853-62. Epub 2010 Aug 1.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre national de la recherche scientifique/Institut National de la Santé et de la Recherche Médicale U964, Université de Strasbourg, F-67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701880PMC
September 2010

Chromatin interaction of TATA-binding protein is dynamically regulated in human cells.

J Cell Sci 2010 Aug 13;123(Pt 15):2663-71. Epub 2010 Jul 13.

Department of Physiological Chemistry and Netherlands Proteomic Center, University Medical Centre Utrecht, Universiteitsweg 100, 3584 CG Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.064097DOI Listing
August 2010

The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties.

EMBO Rep 2010 Aug 16;11(8):612-8. Epub 2010 Jul 16.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/embor.2010.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920448PMC
August 2010

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

EMBO Rep 2010 Jul 28;11(7):541-7. Epub 2010 May 28.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Parc d'Innovation, 1 rue Laurent Fries, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, BP 10142, Illkirch Cedex 67404, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/embor.2010.75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897115PMC
July 2010

The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.

EMBO J 2010 Jul 18;29(14):2381-94. Epub 2010 Jun 18.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U964, Université de Strasbourg, Illkirch Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2010.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910275PMC
July 2010

The TATA box regulates TATA-binding protein (TBP) dynamics in vivo.

Trends Biochem Sci 2010 Jun 21;35(6):309-14. Epub 2010 Feb 21.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibs.2010.01.007DOI Listing
June 2010

TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties.

Mol Cancer Res 2010 Apr 30;8(4):554-68. Epub 2010 Mar 30.

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-09-0159DOI Listing
April 2010

The spectacular landscape of chromatin and ncRNAs under the Tico sunlight.

EMBO Rep 2010 Mar 12;11(3):147-9. Epub 2010 Feb 12.

University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/embor.2010.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838700PMC
March 2010

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes.

Cell Mol Life Sci 2010 Feb 21;67(4):611-28. Epub 2009 Nov 21.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00018-009-0199-8
Publisher Site
http://dx.doi.org/10.1007/s00018-009-0199-8DOI Listing
February 2010

TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.

BMC Mol Biol 2010 Jan 22;11:10. Epub 2010 Jan 22.

RNA Group, Département de Microbiologie et d'Infectiologie, Faculté de Médecine et Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2199-11-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827470PMC
January 2010

The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes.

Nucleic Acids Res 2009 Nov 8;37(20):6665-80. Epub 2009 Sep 8.

Chromatin Research Group of HAS, Department of Biochemistry and Molecular Biology, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkp722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777428PMC
November 2009

Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A.X during mouse preimplantation development in the absence of DNA damage.

Int J Dev Biol 2009 ;53(7):1003-11

Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM U, Universite de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1387/ijdb.082707czDOI Listing
October 2009

TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte.

Genes Dev 2009 Sep;23(18):2210-23

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), UMR 7104 CNRS, UdS, INSERM U964, BP 10142, F-67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.535209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751983PMC
September 2009

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

Mol Cell 2009 Aug;35(3):352-64

Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2009.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749492PMC
August 2009

Human U1 snRNA forms a new chromatin-associated snRNP with TAF15.

EMBO Rep 2009 May 13;10(5):494-500. Epub 2009 Mar 13.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Department of Functional Genomics, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, 1 Rue Laurent Fries, BP 10142, 67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/embor.2009.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680868PMC
May 2009

Keys to open chromatin for transcription activation: FACT and Asf1.

Mol Cell 2009 May;34(4):397-9

Functional Genomics Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, ILLKIRCH, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2009.05.004DOI Listing
May 2009

PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function.

Exp Cell Res 2009 Apr 24;315(7):1273-86. Epub 2008 Dec 24.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 596, Université Louis Pasteur de Strasbourg, Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S001448270800518
Publisher Site
http://dx.doi.org/10.1016/j.yexcr.2008.12.008DOI Listing
April 2009

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

Mol Cell Biol 2009 Mar 29;29(6):1649-60. Epub 2008 Dec 29.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104 CNRS, ULP, INSERM U.964, Parc d'Innovation, Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01076-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648226PMC
March 2009

GPAT: retrieval of genomic annotation from large genomic position datasets.

BMC Bioinformatics 2008 Dec 15;9:533. Epub 2008 Dec 15.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 596, Université Louis Pasteur de Strasbourg, BP 10142-67404 ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-9-533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654044PMC
December 2008

Zinc-finger UBPs: regulators of deubiquitylation.

Trends Biochem Sci 2008 Aug 4;33(8):369-75. Epub 2008 Jul 4.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 596, Université Louis Pasteur de Strasbourg, ILLKIRCH Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibs.2008.05.005DOI Listing
August 2008

TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function.

BMC Mol Biol 2008 Jun 12;9:57. Epub 2008 Jun 12.

Department of Biochemistry and Molecular Biology, University of Szeged, Szeged, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2199-9-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441632PMC
June 2008

TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.

Mol Cancer Res 2008 Jun;6(6):1071-83

Laboratory of Signal Mediated Gene Expression, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vasileos Konstantinou Avenue, Athens 11635, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-07-0375DOI Listing
June 2008

SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC.

EMBO J 2007 Dec 22;26(24):4956-65. Epub 2007 Nov 22.

Department of Regulation of Gene Expression, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.emboj.7601901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140098PMC
December 2007

TBP homologues in embryo transcription: who does what?

EMBO Rep 2007 Nov;8(11):1016-8

Maria Elena Torres-Padilla & Làszlò Tora are at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS/INSERM/ULP, BP 10142, F-67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.embor.7401093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247374PMC
November 2007

Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development.

Reproduction 2007 Jul;134(1):51-62

Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, CNRS, INSERM, ULP, BP 10142, CU de Strasbourg, 67404 Illkirch Cedex, France.

View Article

Download full-text PDF

Source
https://rep.bioscientifica.com/view/journals/rep/134/1/13400
Publisher Site
http://dx.doi.org/10.1530/REP-06-0337DOI Listing
July 2007

New problems in RNA polymerase II transcription initiation: matching the diversity of core promoters with a variety of promoter recognition factors.

J Biol Chem 2007 May 29;282(20):14685-9. Epub 2007 Mar 29.

Institute of Toxicology and Genetics, Forschungszentrum, Karlsruhe, D-76021 Germany.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.R700012200
Publisher Site
http://dx.doi.org/10.1074/jbc.R700012200DOI Listing
May 2007

Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.

PLoS One 2007 Mar 21;2(3):e316. Epub 2007 Mar 21.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U 596, Université Louis Pasteur de Strasbourg, Illkirch, Strasbourg, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000316PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820849PMC
March 2007

The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells.

Cell 2006 Dec;127(7):1375-88

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Campus, Du Cane Road, London W12 ONN, UK.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S009286740601527
Publisher Site
http://dx.doi.org/10.1016/j.cell.2006.10.045DOI Listing
December 2006

Transcriptional alterations and chromatin remodeling in polyglutamine diseases.

Trends Genet 2006 Oct 5;22(10):562-70. Epub 2006 Sep 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01689525060025
Publisher Site
http://dx.doi.org/10.1016/j.tig.2006.07.010DOI Listing
October 2006

Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes.

Biochem Soc Symp 2006 (73):155-63

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, CNRS/IN SER M/ULP, BP 10142, 67404 Illkirch Cedex, France.

View Article

Download full-text PDF

Source
May 2006

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

PLoS Biol 2006 Mar 28;4(3):e67. Epub 2006 Feb 28.

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.0040067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382020PMC
March 2006

An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification.

J Biol Chem 2006 Jan 31;281(1):20-6. Epub 2005 Oct 31.

Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-0032, Japan.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M510157200
Publisher Site
http://dx.doi.org/10.1074/jbc.M510157200DOI Listing
January 2006

Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation.

Proc Natl Acad Sci U S A 2005 Dec 5;102(50):18087-92. Epub 2005 Dec 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de Recherche Scientifique, Unité Mixte de Recherche 7104, Université Louis Pasteur de Strasbourg, BP 10142, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0509063102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1306797PMC
December 2005

The role of enhancers as centres for general transcription factor recruitment.

Trends Biochem Sci 2005 Nov 29;30(11):593-9. Epub 2005 Aug 29.

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Campus, Du Cane Road, London W12 ONN, UK.

View Article

Download full-text PDF

Source
http://www.cell.com/trends/biochemical-sciences/pdf/S0968-00
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S096800040500243
Publisher Site
http://dx.doi.org/10.1016/j.tibs.2005.08.006DOI Listing
November 2005

TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis.

Dev Biol 2005 Sep;285(1):28-37

Department of Physiological Genetics of Nuclear Signaling, UMR 7104, B.P. 10142-67404, ILLKIRCH, C.U. de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2005.05.043DOI Listing
September 2005

TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

Mol Cell Biol 2005 Jun;25(11):4638-49

Department of Transcription, Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.25.11.4638-4649.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140618PMC
June 2005

The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners.

Mol Cell Biol 2005 May;25(10):4092-104

Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, Department of Transcriptional and Post-Transcriptional Control of Gene Regulation, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

View Article

Download full-text PDF

Source
http://mcb.asm.org/cgi/doi/10.1128/MCB.25.10.4092-4104.2005
Publisher Site
http://dx.doi.org/10.1128/MCB.25.10.4092-4104.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087738PMC
May 2005