Lars-Oliver Klotz

Lars-Oliver Klotz

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Lars-Oliver Klotz

Lars-Oliver Klotz

Publications by authors named "Lars-Oliver Klotz"

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Sugar-derived AGEs accelerate pharyngeal pumping rate and increase the lifespan of .

Free Radic Res 2019 13;53(sup1):1056-1067. Epub 2019 Sep 13.

Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1080/10715762.2019.1661403DOI Listing
April 2020

Differential capability of metabolic substrates to promote hepatocellular lipid accumulation.

Eur J Nutr 2019 Dec 27;58(8):3023-3034. Epub 2018 Oct 27.

Institute of Nutritional Sciences, Nutrigenomics, Friedrich-Schiller-Universität Jena, Jena, Germany.

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http://link.springer.com/10.1007/s00394-018-1847-2
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http://dx.doi.org/10.1007/s00394-018-1847-2DOI Listing
December 2019

The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.

Autophagy 2019 Dec 3:1-17. Epub 2019 Dec 3.

Institute of Physiological Chemistry, Martin-Luther University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1080/15548627.2019.1695399DOI Listing
December 2019

Label-free molecular mapping and assessment of glycogen in C. elegans.

Analyst 2019 Mar;144(7):2367-2374

Institute of Nutritional Sciences, Nutrigenomics, Friedrich-Schiller-University Jena, Jena, Germany.

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http://dx.doi.org/10.1039/c8an02351dDOI Listing
March 2019

Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate.

Redox Biol 2019 01 14;20:19-27. Epub 2018 Sep 14.

Institute of Nutritional Sciences, Nutrigenomics, Friedrich-Schiller-Universität Jena, D-07743 Jena, Germany; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317183074
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http://dx.doi.org/10.1016/j.redox.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156746PMC
January 2019

Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes.

Redox Biol 2019 01 10;20:489-495. Epub 2018 Nov 10.

Institute of Biochemistry and Molecular Biology I, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.redox.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249406PMC
January 2019

Insulin suppresses the production of fibroblast growth factor 23 (FGF23).

Proc Natl Acad Sci U S A 2018 05 14;115(22):5804-5809. Epub 2018 May 14.

Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany;

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http://dx.doi.org/10.1073/pnas.1800160115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984514PMC
May 2018

Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPAR.

Oxid Med Cell Longev 2017 6;2017:4397340. Epub 2017 Jul 6.

Institute of Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.

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http://dx.doi.org/10.1155/2017/4397340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518529PMC
April 2018

FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity.

Free Radic Biol Med 2018 04 2;118:98-107. Epub 2018 Mar 2.

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, D-07743 Jena, Germany; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.02.034DOI Listing
April 2018

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Authors:
Javier Egea Isabel Fabregat Yves M Frapart Pietro Ghezzi Agnes Görlach Thomas Kietzmann Kateryna Kubaichuk Ulla G Knaus Manuela G Lopez Gloria Olaso-Gonzalez Andreas Petry Rainer Schulz Jose Vina Paul Winyard Kahina Abbas Opeyemi S Ademowo Catarina B Afonso Ioanna Andreadou Haike Antelmann Fernando Antunes Mutay Aslan Markus M Bachschmid Rui M Barbosa Vsevolod Belousov Carsten Berndt David Bernlohr Esther Bertrán Alberto Bindoli Serge P Bottari Paula M Brito Guia Carrara Ana I Casas Afroditi Chatzi Niki Chondrogianni Marcus Conrad Marcus S Cooke João G Costa Antonio Cuadrado Pham My-Chan Dang Barbara De Smet Bilge Debelec-Butuner Irundika H K Dias Joe Dan Dunn Amanda J Edson Mariam El Assar Jamel El-Benna Péter Ferdinandy Ana S Fernandes Kari E Fladmark Ulrich Förstermann Rashid Giniatullin Zoltán Giricz Anikó Görbe Helen Griffiths Vaclav Hampl Alina Hanf Jan Herget Pablo Hernansanz-Agustín Melanie Hillion Jingjing Huang Serap Ilikay Pidder Jansen-Dürr Vincent Jaquet Jaap A Joles Balaraman Kalyanaraman Danylo Kaminskyy Mahsa Karbaschi Marina Kleanthous Lars-Oliver Klotz Bato Korac Kemal Sami Korkmaz Rafal Koziel Damir Kračun Karl-Heinz Krause Vladimír Křen Thomas Krieg João Laranjinha Antigone Lazou Huige Li Antonio Martínez-Ruiz Reiko Matsui Gethin J McBean Stuart P Meredith Joris Messens Verónica Miguel Yuliya Mikhed Irina Milisav Lidija Milković Antonio Miranda-Vizuete Miloš Mojović María Monsalve Pierre-Alexis Mouthuy John Mulvey Thomas Münzel Vladimir Muzykantov Isabel T N Nguyen Matthias Oelze Nuno G Oliveira Carlos M Palmeira Nikoletta Papaevgeniou Aleksandra Pavićević Brandán Pedre Fabienne Peyrot Marios Phylactides Gratiela G Pircalabioru Andrew R Pitt Henrik E Poulsen Ignacio Prieto Maria Pia Rigobello Natalia Robledinos-Antón Leocadio Rodríguez-Mañas Anabela P Rolo Francis Rousset Tatjana Ruskovska Nuno Saraiva Shlomo Sasson Katrin Schröder Khrystyna Semen Tamara Seredenina Anastasia Shakirzyanova Geoffrey L Smith Thierry Soldati Bebiana C Sousa Corinne M Spickett Ana Stancic Marie José Stasia Holger Steinbrenner Višnja Stepanić Sebastian Steven Kostas Tokatlidis Erkan Tuncay Belma Turan Fulvio Ursini Jan Vacek Olga Vajnerova Kateřina Valentová Frank Van Breusegem Lokman Varisli Elizabeth A Veal A Suha Yalçın Olha Yelisyeyeva Neven Žarković Martina Zatloukalová Jacek Zielonka Rhian M Touyz Andreas Papapetropoulos Tilman Grune Santiago Lamas Harald H H W Schmidt Fabio Di Lisa Andreas Daiber

Redox Biol 2017 10 18;13:94-162. Epub 2017 May 18.

Molecular Cardiology, Center for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany; DZHK (German Centre for Cardiovascular Research), partner site Rhine-Main, Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458069PMC
October 2017

Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors.

Redox Biol 2017 10 3;13:646-654. Epub 2017 Aug 3.

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, D-07743 Jena, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S22132317173044
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http://dx.doi.org/10.1016/j.redox.2017.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558470PMC
October 2017

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin.

Biochim Biophys Acta Gen Subj 2017 May 27;1861(5 Pt A):1057-1064. Epub 2017 Feb 27.

Institute of Nutrition, Department of Nutrigenomics, Friedrich Schiller University, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.02.027DOI Listing
May 2017

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance.

Redox Biol 2017 04 6;11:502-515. Epub 2016 Dec 6.

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, D-07743 Jena, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317163020
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http://dx.doi.org/10.1016/j.redox.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228094PMC
April 2017

Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health.

Crit Rev Toxicol 2015 7;45(9):765-98. Epub 2015 Sep 7.

b Department of Nutrigenomics , Institute of Nutrition, Friedrich Schiller University Jena , Jena , Germany.

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http://dx.doi.org/10.3109/10408444.2015.1074159DOI Listing
September 2016

Selenoproteins: Antioxidant selenoenzymes and beyond.

Arch Biochem Biophys 2016 Apr;595:113-9

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, Jena, Germany.

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http://dx.doi.org/10.1016/j.abb.2015.06.024DOI Listing
April 2016

Peroxynitrite: From interception to signaling.

Arch Biochem Biophys 2016 Apr;595:153-60

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2015.06.022DOI Listing
April 2016

Redox regulation of FoxO transcription factors.

Redox Biol 2015 Dec 3;6:51-72. Epub 2015 Jul 3.

Instituto de Investigaciones Biomédicas "Alberto Sols" (CSIC-UAM), Arturo Duperier, 4, 28029 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511623PMC
December 2015

Stress and biological aging: A double-edged sword.

Z Gerontol Geriatr 2015 Aug 24;48(6):505-10. Epub 2015 Jul 24.

Heart Centre of the University Hospital Halle (Saale), Martin-Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle (Saale), Germany,

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http://dx.doi.org/10.1007/s00391-015-0928-6DOI Listing
August 2015

Arsenite-induced stress signaling: modulation of the phosphoinositide 3'-kinase/Akt/FoxO signaling cascade.

Redox Biol 2013 4;1:104-9. Epub 2013 Feb 4.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1016/j.redox.2012.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757669PMC
May 2015

Modulation of cellular thiol status affects FoxO activity and life span.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S53. Epub 2014 Dec 10.

Friedrich-Schiller-Universität Jena (Institute of Nutrition), Department of Nutrigenomics, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.826DOI Listing
October 2014

Insulin-like modulation of Akt/FoxO signaling by copper ions is independent of insulin receptor.

Arch Biochem Biophys 2014 Sep 13;558:42-50. Epub 2014 Jun 13.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada; Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller Universität Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.06.004DOI Listing
September 2014

1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling.

Molecules 2014 Sep 17;19(9):14902-18. Epub 2014 Sep 17.

Division of Bioorganic Chemistry, School of Pharmacy, Saarland State University, Campus, Building B 2.1., Room 1.13, 66123 Saarbruecken, Germany.

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http://dx.doi.org/10.3390/molecules190914902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270801PMC
September 2014

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling.

Biometals 2014 Apr 18;27(2):317-32. Epub 2014 Feb 18.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1007/s10534-014-9714-yDOI Listing
April 2014

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

Free Radic Biol Med 2014 Feb 24;67:171-87. Epub 2013 Oct 24.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada T6G 2E1; College of Pharmacy, Qatar University, Doha 02713, Qatar. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.10.810DOI Listing
February 2014

Posttranscriptional regulation of connexin-43 expression.

Arch Biochem Biophys 2012 Aug 21;524(1):23-9. Epub 2012 Mar 21.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1016/j.abb.2012.03.012DOI Listing
August 2012

Special Issue: cell-cell communication in development and disease.

Arch Biochem Biophys 2012 Aug;524(1)

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http://dx.doi.org/10.1016/j.abb.2012.05.001DOI Listing
August 2012

Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes.

Drug Metab Dispos 2012 Mar 8;40(3):504-14. Epub 2011 Dec 8.

Faculty of Pharmacy and Pharmaceutical Sciences, 3126 Dentistry/Pharmacy Centre, University of Alberta, Edmonton, Alberta, Canada T6G 2N8.

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http://www.medicinabiomolecular.com.br/biblioteca/pdfs/Cance
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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.111.042564
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http://dx.doi.org/10.1124/dmd.111.042564DOI Listing
March 2012

Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct.

Arch Biochem Biophys 2011 Dec 15;516(2):138-45. Epub 2011 Oct 15.

Leibniz-Institut für umweltmedizinische Forschung, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.abb.2011.10.006DOI Listing
December 2011

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to carbon or silica-based nanoparticles.

Biol Chem 2010 Nov;391(11):1333-9

Leibniz-Institut für umweltmedizinische Forschung (IUF), Auf'm Hennekamp 50, Düsseldorf, Germany.

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https://www.degruyter.com/view/j/bchm.2010.391.issue-11/bc.2
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http://dx.doi.org/10.1515/BC.2010.133DOI Listing
November 2010

Highlight: xenobiotics and cell signaling.

Biol Chem 2010 Nov;391(11):1233-4

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http://dx.doi.org/10.1515/BC.2010.142DOI Listing
November 2010

Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture.

Arch Biochem Biophys 2010 Sep 27;501(1):58-64. Epub 2010 May 27.

Leibniz-Institut für umweltmedizinische Forschung (IUF), D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.abb.2010.05.024DOI Listing
September 2010

1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.

Arch Biochem Biophys 2010 Apr 12;496(2):93-100. Epub 2010 Feb 12.

Institut für Lebensmitteltechnologie und Lebensmittelchemie, Technische Universität Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.abb.2010.02.002DOI Listing
April 2010

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles.

Biochem Biophys Res Commun 2009 Dec 18;390(1):44-7. Epub 2009 Sep 18.

Institut für Umweltmedizinische Forschung at Heinrich-Heine Universität Düsseldorf gGmbH, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2009.09.057DOI Listing
December 2009

HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity.

Hepatology 2009 Nov;50(5):1567-76

Institut für umweltmedizinische Forschung (IUF) an der Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1002/hep.23146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784158PMC
November 2009

Heavy metal ion-induced insulin-mimetic signaling.

Redox Rep 2009 ;14(4):141-6

Institut für umweltmedizinische Forschung an der Heinrich-Heine-Universität Düsseldorf (IUF), Düsseldorf, Germany.

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http://dx.doi.org/10.1179/135100009X392610DOI Listing
October 2009

Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense.

Mol Pharm 2008 Nov-Dec;5(6):1138-44

Institut für Entwicklungs- und Molekularbiologie der Tiere, Heinrich-Heine-University, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1021/mp8001232DOI Listing
June 2009

Zinc fingers as biologic redox switches?

Antioxid Redox Signal 2009 May;11(5):1015-27

Institute of Biochemistry and Molecular Biology I, Heinrich-Heine University of Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1089/ARS.2008.2269DOI Listing
May 2009

Nickel and copper ion-induced stress signaling in human hepatoma cells: analysis of phosphoinositide 3'-kinase/Akt signaling.

Biometals 2009 Apr 17;22(2):307-16. Epub 2008 Oct 17.

Institut für umweltmedizinische Forschung (IUF) an der Heinrich-Heine-Universität Düsseldorf gGmbH, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1007/s10534-008-9167-2DOI Listing
April 2009

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors.

Hepatology 2008 Dec;48(6):1998-2006

Institute for Biochemistry and Molecular Biology I, Hepatology and Infectiology, Heinrich-Heine-University, Düsseldorf, Germany.

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http://doi.wiley.com/10.1002/hep.22526
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http://dx.doi.org/10.1002/hep.22526DOI Listing
December 2008

Highlight: oxidative stress and senescence.

Biol Chem 2008 Mar;389(3):201

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http://dx.doi.org/10.1515/BC.2008.044DOI Listing
March 2008

Stimulation of selenoprotein P promoter activity in hepatoma cells by FoxO1a transcription factor.

Biochem Biophys Res Commun 2008 Jan 5;365(2):316-21. Epub 2007 Nov 5.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2007.10.171DOI Listing
January 2008

Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells.

Biochem Biophys Res Commun 2007 Dec 11;364(2):313-7. Epub 2007 Oct 11.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2007.09.132DOI Listing
December 2007

Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences.

Arch Biochem Biophys 2007 Jul 4;463(2):175-82. Epub 2007 May 4.

Medizinische Klinik I, BG Kliniken Bergmannsheil, Ruhr-Universität, Bochum, Germany.

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http://dx.doi.org/10.1016/j.abb.2007.04.015DOI Listing
July 2007

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin.

Free Radic Biol Med 2007 Apr 22;42(7):955-70. Epub 2006 Dec 22.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2006.12.024DOI Listing
April 2007

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

Free Radic Biol Med 2007 Mar 2;42(6):773-86. Epub 2006 Dec 2.

Research Institute of Environmental Medicine, Heinrich Heine University, Auf'm Hennekamp 50, 40225 Duesseldorf, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2006.11.029DOI Listing
March 2007

Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine.

Biol Chem 2006 Oct-Nov;387(10-11):1399-404

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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https://www.degruyter.com/view/j/bchm.2006.387.issue-10_11/b
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http://dx.doi.org/10.1515/BC.2006.175DOI Listing
December 2006

Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation.

Free Radic Biol Med 2006 Nov 11;41(9):1478-87. Epub 2006 Aug 11.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2006.08.005DOI Listing
November 2006

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions.

Arch Biochem Biophys 2006 Oct 30;454(2):107-13. Epub 2006 Aug 30.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.abb.2006.08.016DOI Listing
October 2006

Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases.

FEBS Lett 2006 Mar 28;580(7):1859-64. Epub 2006 Feb 28.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Universitätsstr. 1, Geb. 22.03; D-40225 Düsseldorf, Germany.

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http://doi.wiley.com/10.1016/j.febslet.2006.02.048
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http://dx.doi.org/10.1016/j.febslet.2006.02.048DOI Listing
March 2006

Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress.

Biol Chem 2005 Mar;386(3):207-16

Abteilung für Endokrinologie, Diabetologie und Rheumatologie, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1515/BC.2005.026DOI Listing
March 2005

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells.

Biol Chem 2005 Mar;386(3):217-23

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1515/BC.2005.027DOI Listing
March 2005

Dicumarol is a potent reversible inhibitor of gap junctional intercellular communication.

Arch Biochem Biophys 2005 Feb;434(2):241-7

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.abb.2004.11.002DOI Listing
February 2005

Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation.

Biochem Biophys Res Commun 2005 Feb;327(4):1016-23

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X040292
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http://dx.doi.org/10.1016/j.bbrc.2004.12.107DOI Listing
February 2005

Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin.

Biochem Biophys Res Commun 2005 Jan;326(3):614-7

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2004.11.089DOI Listing
January 2005

Role of myoglobin in the antioxidant defense of the heart.

FASEB J 2004 Jul 7;18(10):1156-8. Epub 2004 May 7.

Institut für Herz- und Kreislaufphysiologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1096/fj.03-1382fjeDOI Listing
July 2004

Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.

Free Radic Res 2004 Jul;38(7):729-37

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1080/10715760410001712764DOI Listing
July 2004

Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation.

Methods Enzymol 2004 ;378:258-72

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Germany.

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http://dx.doi.org/10.1016/S0076-6879(04)78020-9DOI Listing
April 2004

Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis.

Photochem Photobiol Sci 2004 Mar 6;3(3):257-62. Epub 2004 Feb 6.

Institut fur Biochemie und Molekularbiologie I, Heinrich-Heine-Universitat Dusseldorf, 40225 Dusseldorf, Germany.

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http://xlink.rsc.org/?DOI=B309067A
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http://dx.doi.org/10.1039/b309067aDOI Listing
March 2004

Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis.

J Invest Dermatol 2004 Feb;122(2):477-83

Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

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http://dx.doi.org/10.1046/j.0022-202X.2003.22106.xDOI Listing
February 2004

Selenoprotein P protects low-density lipoprotein against oxidation.

Free Radic Res 2004 Feb;38(2):123-8

Institute for Biochemistry and Molecular Biology I, Heinrich-Heine-University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.

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http://dx.doi.org/10.1080/10715760320001634852DOI Listing
February 2004

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential.

Org Biomol Chem 2003 Dec 4;1(23):4317-22. Epub 2003 Nov 4.

School of Biological and Chemical Sciences, University of Exeter, Stocker Road, Exeter, UK EX4 4QD.

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http://dx.doi.org/10.1039/b308117fDOI Listing
December 2003

Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases.

J Biol Chem 2003 Oct 21;278(40):38360-7. Epub 2003 Jul 21.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M306785200
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http://dx.doi.org/10.1074/jbc.M306785200DOI Listing
October 2003

Selenenyl iodide: a new substrate for mammalian thioredoxin reductase.

Org Biomol Chem 2003 Aug;1(16):2848-52

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, D-40001 Düsseldorf, Germany.

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http://dx.doi.org/10.1039/b302220jDOI Listing
August 2003

Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite.

Biochem Biophys Res Commun 2003 Jul;307(1):69-73

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, Gebäude 22.03 E02.R31, Universitätsstrasse 1, D-40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/s0006-291x(03)01132-xDOI Listing
July 2003

Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress.

J Nutr 2003 05;133(5 Suppl 1):1448S-51S

Institut für Biochemie and Molekularbiologie I, Düsseldorf, 40001 Düsseldorf, Germany.

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http://dx.doi.org/10.1093/jn/133.5.1448SDOI Listing
May 2003

Critical role of L-arginine in endothelial cell survival during oxidative stress.

Circulation 2003 May 12;107(20):2607-14. Epub 2003 May 12.

Research Group Immunobiology, Geb.: 23.12.02, Heinrich-Heine-University Duesseldorf, PO Box 10 10 07, D-40001 Duesseldorf, Germany.

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http://dx.doi.org/10.1161/01.CIR.0000066909.13953.F1DOI Listing
May 2003

Defenses against peroxynitrite: selenocompounds and flavonoids.

Toxicol Lett 2003 Apr;140-141:125-32

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, D-40001, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/s0378-4274(02)00511-8DOI Listing
April 2003

Irradiation of cells with ultraviolet-A (320-400 nm) in the presence of cell culture medium elicits biological effects due to extracellular generation of hydrogen peroxide.

Free Radic Res 2003 Apr;37(4):391-7

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, D-40001 Düsseldorf, Germany.

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http://dx.doi.org/10.1080/1071576031000064702DOI Listing
April 2003

Singlet oxygen-induced signaling effects in mammalian cells.

Photochem Photobiol Sci 2003 Feb;2(2):88-94

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1039/b210750cDOI Listing
February 2003

Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver.

Biol Chem 2003 Feb;384(2):213-8

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, D-40001 Düsseldorf, Germany.

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http://dx.doi.org/10.1515/BC.2003.023DOI Listing
February 2003

Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome.

Biol Chem 2003 Feb;384(2):237-41

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, D-40001 Düsseldorf, Germany.

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http://dx.doi.org/10.1515/BC.2003.026DOI Listing
February 2003

Oxidant-induced signaling: effects of peroxynitrite and singlet oxygen.

Biol Chem 2002 Mar-Apr;383(3-4):443-56

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Germany.

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http://dx.doi.org/10.1515/BC.2002.047DOI Listing
November 2002

Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

Free Radic Biol Med 2002 Sep;33(6):737-43

Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/s0891-5849(02)00892-4DOI Listing
September 2002

Selenoprotein P.

Methods Enzymol 2002 ;347:121-5

Laboratory of Hepatobiology and Toxicology, Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)47013-9DOI Listing
August 2002

Reversible conversion of nitroxyl anion to nitric oxide.

Methods Enzymol 2002 ;349:101-6

Institute for Physiological Chemistry I, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/s0076-6879(02)49325-1DOI Listing
May 2002

Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO.

J Biol Chem 2002 Apr 16;277(15):13294-301. Epub 2002 Jan 16.

Research Group Immunobiology, Biomedical Research Center, Medical Department of the Heinrich-Heine-University, Moorenstrasse 5, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1074/jbc.M111216200DOI Listing
April 2002

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species.

Arch Biochem Biophys 2002 Jan;397(2):232-9

Klinik für Gastroenterologie, Hepatologie, und Infektionsbiologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1006/abbi.2001.2559DOI Listing
January 2002