Publications by authors named "Lars Ruddigkeit"

6Publications

Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2.

ChemMedChem 2019 01 6;14(2):224-236. Epub 2018 Dec 6.

Department of Chemistry and Biochemistry, National Center of Competence in Research NCCR TransCure, University of Bern, Freiestrasse 3, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1002/cmdc.201800554DOI Listing
January 2019

Expanding the fragrance chemical space for virtual screening.

J Cheminform 2014 22;6:27. Epub 2014 May 22.

Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, 3012 Bern, Switzerland.

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http://dx.doi.org/10.1186/1758-2946-6-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037718PMC
May 2014

Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation.

Free Radic Biol Med 2014 May 12;70:255-64. Epub 2014 Mar 12.

Institute of Human Nutrition and Food Science, Christian-Albrechts-University Kiel, D-24118 Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.02.025DOI Listing
May 2014

Visualization and virtual screening of the chemical universe database GDB-17.

J Chem Inf Model 2013 Jan 9;53(1):56-65. Epub 2013 Jan 9.

Department of Chemistry and Biochemistry, University of Berne, Freiestrasse 3, 3012 Berne, Switzerland.

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http://dx.doi.org/10.1021/ci300535xDOI Listing
January 2013

Enumeration of 166 billion organic small molecules in the chemical universe database GDB-17.

J Chem Inf Model 2012 Nov 1;52(11):2864-75. Epub 2012 Nov 1.

Department of Chemistry and Biochemistry, NCCR TransCure, University of Berne, Freiestrasse 3, 3012 Berne, Switzerland.

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http://dx.doi.org/10.1021/ci300415dDOI Listing
November 2012