Lars K Nielsen

Lars K Nielsen

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Lars K Nielsen

Publications by authors named "Lars K Nielsen"

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Stoichiometric gene-to-reaction associations enhance model-driven analysis performance: Metabolic response to chronic exposure to Aldrin in prostate cancer.

BMC Genomics 2019 Aug 15;20(1):652. Epub 2019 Aug 15.

Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona 18-24, 08034, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12864-019-5979-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694502PMC
August 2019

Revisiting the Evolution and Taxonomy of Clostridia, a Phylogenomic Update.

Genome Biol Evol 2019 07;11(7):2035-2044

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.

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http://dx.doi.org/10.1093/gbe/evz096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656338PMC
July 2019

Systems-level engineering and characterisation of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB).

Metab Eng 2019 05 11;53:14-23. Epub 2019 Jan 11.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia; Metabolomics Australia, AIBN, The University of Queensland, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2019.01.003DOI Listing
May 2019

Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect.

Biotechnol Bioeng 2018 09 22;115(9):2315-2327. Epub 2018 May 22.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/bit.26724DOI Listing
September 2018

Linking genotype and phenotype in an economically viable propionic acid biosynthesis process.

Biotechnol Biofuels 2018 13;11:224. Epub 2018 Aug 13.

1Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072 Australia.

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http://dx.doi.org/10.1186/s13068-018-1222-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090647PMC
August 2018

Genome-scale model guided design of for enhanced propionic acid production.

Metab Eng Commun 2018 Jun 24;6:1-12. Epub 2017 Nov 24.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia.

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http://dx.doi.org/10.1016/j.meteno.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725212PMC
June 2018

Engineered protein degradation of farnesyl pyrophosphate synthase is an effective regulatory mechanism to increase monoterpene production in Saccharomyces cerevisiae.

Metab Eng 2018 05 19;47:83-93. Epub 2018 Feb 19.

Australian Institute for Bioengineering and Nanotechnology (AIBN), the University of Queensland, St. Lucia QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176173021
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http://dx.doi.org/10.1016/j.ymben.2018.02.005DOI Listing
May 2018

RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells.

Biotechnol J 2018 Mar 1;13(3):e1700231. Epub 2018 Feb 1.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.

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http://dx.doi.org/10.1002/biot.201700231DOI Listing
March 2018

Toward Synthetic Biology Strategies for Adipic Acid Production: An in Silico Tool for Combined Thermodynamics and Stoichiometric Analysis of Metabolic Networks.

ACS Synth Biol 2018 02 26;7(2):490-509. Epub 2017 Dec 26.

Centre for Microbial Electrochemical Systems (CEMES), Advanced Water Management Centre (AWMC), The University of Queensland , Brisbane 4072, Australia.

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http://dx.doi.org/10.1021/acssynbio.7b00304DOI Listing
February 2018

An Expanded Heterologous GAL Promoter Collection for Diauxie-Inducible Expression in Saccharomyces cerevisiae.

ACS Synth Biol 2018 02 23;7(2):748-751. Epub 2018 Jan 23.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland , Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1021/acssynbio.7b00355DOI Listing
February 2018

Universal Alternative Splicing of Noncoding Exons.

Cell Syst 2018 Feb 24;6(2):245-255.e5. Epub 2018 Jan 24.

Garvan Institute of Medical Research, Sydney, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia; Altius Institute for Biomedical Sciences, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.12.005DOI Listing
February 2018

Quantitative analysis of tetrahydrofolate metabolites from clostridium autoethanogenum.

Metabolomics 2018 02 16;14(3):35. Epub 2018 Feb 16.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/s11306-018-1331-2DOI Listing
February 2018

Formulation, construction and analysis of kinetic models of metabolism: A review of modelling frameworks.

Biotechnol Adv 2017 Dec 13;35(8):981-1003. Epub 2017 Sep 13.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, Building 220, DK-2800 Kongens Lyngby, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.biotechadv.2017.09.005DOI Listing
December 2017

Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells.

Biotechnol Bioeng 2017 08 8;114(8):1825-1836. Epub 2017 May 8.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia.

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http://doi.wiley.com/10.1002/bit.26316
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http://dx.doi.org/10.1002/bit.26316DOI Listing
August 2017

Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum.

Metab Eng 2017 05 23;41:202-211. Epub 2017 Apr 23.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176163013
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http://dx.doi.org/10.1016/j.ymben.2017.04.007DOI Listing
May 2017

Improved production of propionic acid using genome shuffling.

Biotechnol J 2017 Feb 20;12(2). Epub 2016 Oct 20.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1002/biot.201600120DOI Listing
February 2017

Coupling gene regulatory patterns to bioprocess conditions to optimize synthetic metabolic modules for improved sesquiterpene production in yeast.

Biotechnol Biofuels 2017 21;10:43. Epub 2017 Feb 21.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD 4072 Australia.

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http://dx.doi.org/10.1186/s13068-017-0728-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320780PMC
February 2017

A squalene synthase protein degradation method for improved sesquiterpene production in Saccharomyces cerevisiae.

Metab Eng 2017 01 8;39:209-219. Epub 2016 Dec 8.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176163024
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http://dx.doi.org/10.1016/j.ymben.2016.12.003DOI Listing
January 2017

The pheromone-response is a metabolically active stationary phase for bio-production.

Metab Eng Commun 2016 Dec 11;3:142-152. Epub 2016 May 11.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.meteno.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779721PMC
December 2016

Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models.

Bioinformatics 2016 12 24;32(24):3807-3814. Epub 2016 Aug 24.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Corner College and Cooper Rds (Bldg 75), Australia.

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http://dx.doi.org/10.1093/bioinformatics/btw555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167067PMC
December 2016

In vitro production of baculoviruses: identifying host and virus genes associated with high productivity.

Appl Microbiol Biotechnol 2016 Nov 9;100(21):9239-9253. Epub 2016 Sep 9.

School of Chemistry & Molecular Biosciences, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/s00253-016-7774-3DOI Listing
November 2016

Tetanus toxin production is triggered by the transition from amino acid consumption to peptides.

Anaerobe 2016 Oct 1;41:113-124. Epub 2016 Aug 1.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.anaerobe.2016.07.006DOI Listing
October 2016

Representing genetic variation with synthetic DNA standards.

Nat Methods 2016 09 8;13(9):784-91. Epub 2016 Aug 8.

Genomics and Epigenetics Division, Garvan Institute of Medical Research, New South Wales, Australia.

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http://dx.doi.org/10.1038/nmeth.3957DOI Listing
September 2016

Spliced synthetic genes as internal controls in RNA sequencing experiments.

Nat Methods 2016 09 8;13(9):792-8. Epub 2016 Aug 8.

Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1038/nmeth.3958DOI Listing
September 2016

ll-ACHRB: a scalable algorithm for sampling the feasible solution space of metabolic networks.

Bioinformatics 2016 08 11;32(15):2330-7. Epub 2016 Mar 11.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St Lucia, QLD, Australia.

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http://dx.doi.org/10.1093/bioinformatics/btw132DOI Listing
August 2016

Construction of feasible and accurate kinetic models of metabolism: A Bayesian approach.

Sci Rep 2016 07 15;6:29635. Epub 2016 Jul 15.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1038/srep29635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945864PMC
July 2016

Recon 2.2: from reconstruction to model of human metabolism.

Metabolomics 2016;12:109. Epub 2016 Jun 7.

Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN UK ; School of Computer Science, The University of Manchester, Manchester, M13 9PL UK ; Center for Quantitative Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT 06030-6033 USA.

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http://dx.doi.org/10.1007/s11306-016-1051-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896983PMC
June 2016

Genome Sequence of Propionibacterium acidipropionici ATCC 55737.

Genome Announc 2016 May 19;4(3). Epub 2016 May 19.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Australia

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http://dx.doi.org/10.1128/genomeA.00248-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888987PMC
May 2016

A probabilistic framework for the exploration of enzymatic capabilities based on feasible kinetics and control analysis.

Biochim Biophys Acta 2016 Mar 22;1860(3):576-87. Epub 2015 Dec 22.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Australia, Corner College and Cooper Rds (Bldg 75), The University of Queensland, QLD 4072, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2015.12.015DOI Listing
March 2016

Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineering.

Plant Biotechnol J 2016 Feb 25;14(2):567-80. Epub 2015 May 25.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1111/pbi.12399DOI Listing
February 2016

Filling the void: allogeneic myeloid cells for transplantation.

Curr Opin Hematol 2016 Jan;23(1):72-7

aAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland bMater Research Institute - University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia *Jessica L. Schwaber and Marion E. Brunck contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/MOH.0000000000000205DOI Listing
January 2016

Systems Biology Approaches to Understand Natural Products Biosynthesis.

Front Bioeng Biotechnol 2015 9;3:199. Epub 2015 Dec 9.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland , Brisbane, QLD , Australia.

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http://dx.doi.org/10.3389/fbioe.2015.00199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673338PMC
December 2015

AllR Controls the Expression of Streptomyces coelicolor Allantoin Pathway Genes.

Appl Environ Microbiol 2015 Oct 17;81(19):6649-59. Epub 2015 Jul 17.

Instituto de Biología Molecular y Celular de Rosario (IBR-Consejo Nacional de Investigaciones Científicas y Técnicas), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina

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http://aem.asm.org/lookup/doi/10.1128/AEM.02098-15
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http://dx.doi.org/10.1128/AEM.02098-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561711PMC
October 2015

Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levels.

Arch Virol 2015 Sep 21;160(9):2169-80. Epub 2015 Jun 21.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia,

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http://dx.doi.org/10.1007/s00705-015-2478-zDOI Listing
September 2015

Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions.

J Proteomics 2015 Aug 23;126:24-33. Epub 2015 May 23.

Australian Institute for Bioengineering and Nanotechnology (AIBN), Corner College and Coopers Rd, The University of Queensland, St Lucia, QLD 4072, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S18743919153002
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http://dx.doi.org/10.1016/j.jprot.2015.05.021DOI Listing
August 2015

NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network.

Methods Mol Biol 2014 ;1191:65-78

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Building 75, Corner of College and Cooper Road, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/978-1-4939-1170-7_4DOI Listing
May 2015

Customization of ¹³C-MFA strategy according to cell culture system.

Methods Mol Biol 2014 ;1191:81-90

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Building 75, Corner of College and Cooper Road, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/978-1-4939-1170-7_5DOI Listing
May 2015

Steady-state ¹³C fluxomics using OpenFLUX.

Methods Mol Biol 2014 ;1191:209-24

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Building 75, Corner of College and Cooper Road, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/978-1-4939-1170-7_13DOI Listing
May 2015

Evolutionary Engineering Improves Tolerance for Replacement Jet Fuels in Saccharomyces cerevisiae.

Appl Environ Microbiol 2015 May 6;81(10):3316-25. Epub 2015 Mar 6.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1128/AEM.04144-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407233PMC
May 2015

Intracellular Trafficking of Baculovirus Particles: A Quantitative Study of the HearNPV/HzAM1 Cell and AcMNPV/Sf9 Cell Systems.

Viruses 2015 May 5;7(5):2288-307. Epub 2015 May 5.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, QLD 4072, Australia.

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http://dx.doi.org/10.3390/v7052288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452906PMC
May 2015

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing.

Nat Methods 2015 Apr 9;12(4):339-42. Epub 2015 Mar 9.

1] Garvan Institute of Medical Research, Sydney, Australia. [2] St Vincents Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1038/nmeth.3321DOI Listing
April 2015

A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactions.

PLoS Comput Biol 2015 Apr 14;11(4):e1004195. Epub 2015 Apr 14.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.

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https://dx.plos.org/10.1371/journal.pcbi.1004195
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http://dx.doi.org/10.1371/journal.pcbi.1004195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397067PMC
April 2015

Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae.

Microb Cell Fact 2015 Apr 1;14:43. Epub 2015 Apr 1.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD, 4072, Australia.

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http://dx.doi.org/10.1186/s12934-015-0223-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427958PMC
April 2015

Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yields.

Appl Microbiol Biotechnol 2015 Feb 5;99(4):1687-700. Epub 2014 Dec 5.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia,

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http://dx.doi.org/10.1007/s00253-014-6260-zDOI Listing
February 2015

High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis.

J Proteome Res 2015 Feb 14;14(2):609-18. Epub 2015 Jan 14.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland , Corner College and Cooper Roads (Bldg 75), Brisbane, QLD 4072, Australia.

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http://pubs.acs.org/doi/10.1021/pr501027c
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http://dx.doi.org/10.1021/pr501027cDOI Listing
February 2015

Genome-wide discovery of human splicing branchpoints.

Genome Res 2015 Feb 5;25(2):290-303. Epub 2015 Jan 5.

Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia; St. Vincent's Clinical School, Faculty of Medicine, UNSW Australia, Sydney, New South Wales 2052, Australia;

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http://genome.cshlp.org/lookup/doi/10.1101/gr.182899.114
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http://dx.doi.org/10.1101/gr.182899.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315302PMC
February 2015

A multi-tissue genome-scale metabolic modeling framework for the analysis of whole plant systems.

Front Plant Sci 2015 22;6. Epub 2015 Jan 22.

Centre for Systems and Synthetic Biology, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland Brisbane, Qld, Australia.

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http://dx.doi.org/10.3389/fpls.2015.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302846PMC
February 2015

Absolute counting of neutrophils in whole blood using flow cytometry.

Cytometry A 2014 Dec 3;85(12):1057-64. Epub 2014 Jul 3.

The University of Queensland, Australian Institute for Bioengineering and Nanotechnology (AIBN), Brisbane, Queensland, 4072, Australia.

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http://dx.doi.org/10.1002/cyto.a.22503DOI Listing
December 2014

Dynamic balancing of isoprene carbon sources reflects photosynthetic and photorespiratory responses to temperature stress.

Plant Physiol 2014 Dec 15;166(4):2051-64. Epub 2014 Oct 15.

Climate Science Department, Earth Science Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (K.J., J.C., J.H., M.S.T.);National Institute for Amazon Research, Manaus, Amazonas 69080-971, Brazil (E.G.A., A.T., S.G., N.H., A.M.);Departments of Chemistry and Biochemistry and Soil, Water, and Environmental Science, University of Arizona, Tucson, Arizona 85721 (L.A.);Department of Meteorology, College of Earth and Mineral Sciences, Pennsylvania State University, University Park, Pennsylvania 16802 (J.D.F.); andAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, St. Lucia, Queensland 4072, Australia (L.K.N., C.E.V.).

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http://dx.doi.org/10.1104/pp.114.247494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256868PMC
December 2014

Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formation.

Appl Microbiol Biotechnol 2014 Nov 16;98(21):9033-44. Epub 2014 Aug 16.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/s00253-014-5956-4DOI Listing
November 2014

Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass.

BMC Biotechnol 2014 Sep 10;14:83. Epub 2014 Sep 10.

Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, Brisbane QLD 4072, Australia.

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http://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472
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http://dx.doi.org/10.1186/1472-6750-14-83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165624PMC
September 2014

Reducing Recon 2 for steady-state flux analysis of HEK cell culture.

J Biotechnol 2014 Aug 5;184:172-8. Epub 2014 Jun 5.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Queensland, Australia.

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http://dx.doi.org/10.1016/j.jbiotec.2014.05.021DOI Listing
August 2014

Insight into hyaluronic acid molecular weight control.

Appl Microbiol Biotechnol 2014 Aug 24;98(16):6947-56. Epub 2014 Jun 24.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, 4072, QLD, Australia,

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http://dx.doi.org/10.1007/s00253-014-5853-xDOI Listing
August 2014

Production of the short peptide surfactant DAMP4 from glucose or sucrose in high cell density cultures of Escherichia coli BL21(DE3).

Microb Cell Fact 2014 Aug 19;13:99. Epub 2014 Aug 19.

Centre for Microbial Electrosynthesis (CEMES), Advanced Water Management Centre (AWMC), Research Road (Bldg 60), The University of Queensland, St, Lucia 4072, QLD, Australia.

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http://dx.doi.org/10.1186/s12934-014-0099-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229601PMC
August 2014

Plant genome-scale modeling and implementation.

Methods Mol Biol 2014 ;1090:317-32

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1007/978-1-62703-688-7_19DOI Listing
July 2014

Network thermodynamic curation of human and yeast genome-scale metabolic models.

Biophys J 2014 Jul;107(2):493-503

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104063PMC
July 2014

Temporal dynamics of the Saccharopolyspora erythraea phosphoproteome.

Mol Cell Proteomics 2014 May 10;13(5):1219-30. Epub 2014 Mar 10.

§Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St Lucia, QLD 4072, Australia.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M113.033951
Publisher Site
http://dx.doi.org/10.1074/mcp.M113.033951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014280PMC
May 2014

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq.

Nat Protoc 2014 May 3;9(5):989-1009. Epub 2014 Apr 3.

Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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May 2014

Concise review: next-generation cell therapies to prevent infections in neutropenic patients.

Stem Cells Transl Med 2014 Apr 5;3(4):541-8. Epub 2014 Mar 5.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St. Lucia, Queensland, Australia.

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http://dx.doi.org/10.5966/sctm.2013-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973713PMC
April 2014

The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality.

Arch Virol 2014 Jan 25;159(1):91-102. Epub 2013 Jul 25.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, QLD, 4072, Australia,

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January 2014

Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor.

Appl Microbiol Biotechnol 2014 Jan 29;98(1):351-60. Epub 2013 Nov 29.

Instituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK, Rosario, Argentina.

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January 2014

Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane.

Plant Biotechnol J 2013 Dec 25;11(9):1146-51. Epub 2013 Sep 25.

Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, Brisbane, Qld, Australia.

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http://doi.wiley.com/10.1111/pbi.12109
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December 2013

Genome scale transcriptomics of baculovirus-insect interactions.

Viruses 2013 Nov 12;5(11):2721-47. Epub 2013 Nov 12.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia.

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http://dx.doi.org/10.3390/v5112721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856412PMC
November 2013

Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach.

BMC Genomics 2013 Oct 11;14:699. Epub 2013 Oct 11.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.1186/1471-2164-14-699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008361PMC
October 2013

Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae.

Microb Cell Fact 2013 Oct 25;12:96. Epub 2013 Oct 25.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane St Lucia QLD 4072, Australia.

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http://dx.doi.org/10.1186/1475-2859-12-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231455PMC
October 2013

Non-invasive monitoring of sucrose mobilization from culm storage parenchyma by magnetic resonance spectroscopy.

Biosci Biotechnol Biochem 2013 7;77(3):487-96. Epub 2013 Mar 7.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland.

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September 2013

Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus.

Virology 2013 Sep 1;444(1-2):158-70. Epub 2013 Jul 1.

Australian Institute for Bioengineering and Nanotechnology, Building 75, Corner College/Cooper Road, The University of Queensland, St. Lucia, Qld 4072, Australia. Electronic address:

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September 2013

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis.

Microb Cell Fact 2013 Aug 23;12:76. Epub 2013 Aug 23.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia QLD 4072, Australia.

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http://dx.doi.org/10.1186/1475-2859-12-76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847554PMC
August 2013

Decline in baculovirus-expressed recombinant protein production with increasing cell density is strongly correlated to impairment of virus replication and mRNA expression.

Appl Microbiol Biotechnol 2013 Jun 22;97(12):5245-57. Epub 2013 Mar 22.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Qld 4072, Australia.

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June 2013

Physiological and transcriptional responses of Saccharomyces cerevisiae to d-limonene show changes to the cell wall but not to the plasma membrane.

Appl Environ Microbiol 2013 Jun 29;79(12):3590-600. Epub 2013 Mar 29.

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1128/AEM.00463-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675946PMC
June 2013

Knock-in/Knock-out (KIKO) vectors for rapid integration of large DNA sequences, including whole metabolic pathways, onto the Escherichia coli chromosome at well-characterised loci.

Microb Cell Fact 2013 Jun 24;12:60. Epub 2013 Jun 24.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1186/1475-2859-12-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706339PMC
June 2013

Bioreactor for blood product production.

Cell Transplant 2012 8;21(6):1235-44. Epub 2012 Mar 8.

Stem Cell Therapies Laboratory, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.3727/096368911X627363DOI Listing
May 2013

A multi-omics analysis of recombinant protein production in Hek293 cells.

PLoS One 2012 24;7(8):e43394. Epub 2012 Aug 24.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427347PMC
April 2013

Engineered quorum sensing using pheromone-mediated cell-to-cell communication in Saccharomyces cerevisiae.

ACS Synth Biol 2013 Mar 7;2(3):136-49. Epub 2013 Jan 7.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland , St. Lucia, QLD 4072, Australia.

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http://dx.doi.org/10.1021/sb300110bDOI Listing
March 2013

Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption.

Biotechnol Bioeng 2013 Feb 5;110(2):660-6. Epub 2012 Nov 5.

Australian Institute for Bioengineering and Nanotechnology-AIBN, The University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1002/bit.24728DOI Listing
February 2013

PATHLOGIC-S: a scalable Boolean framework for modelling cellular signalling.

PLoS One 2012 7;7(8):e41977. Epub 2012 Aug 7.

Australian Institute of Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413702PMC
January 2013

Molecular control of sucrose utilization in Escherichia coli W, an efficient sucrose-utilizing strain.

Appl Environ Microbiol 2013 Jan 2;79(2):478-87. Epub 2012 Nov 2.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, St. Lucia, QLD, Australia.

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http://dx.doi.org/10.1128/AEM.02544-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553775PMC
January 2013

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch.

BMC Genomics 2013 Jan 16;14:15. Epub 2013 Jan 16.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.1186/1471-2164-14-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610266PMC
January 2013

Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions.

PLoS One 2012 18;7(5):e36324. Epub 2012 May 18.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356360PMC
December 2012

RNAi-mediated abrogation of trehalase expression does not affect trehalase activity in sugarcane.

Springerplus 2012 Dec 21;1(1):74. Epub 2012 Dec 21.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland 4072 Australia ; BSES Limited, PO Box 86, Indooroopilly, Queensland 4068 Australia.

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http://dx.doi.org/10.1186/2193-1801-1-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606522PMC
December 2012

Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae.

Biotechnol Bioeng 2012 Oct 28;109(10):2513-22. Epub 2012 May 28.

Australian Institute for Bioengineering and Nanotechnology (AIBN), University of Queensland, Brisbane Qld 4072, Australia.

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http://dx.doi.org/10.1002/bit.24536DOI Listing
October 2012

Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production.

Antonie Van Leeuwenhoek 2012 Oct 31;102(3):493-502. Epub 2012 Jul 31.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.

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http://dx.doi.org/10.1007/s10482-012-9783-2DOI Listing
October 2012

Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter.

Metab Eng 2012 Sep 4;14(5):469-76. Epub 2012 Aug 4.

Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México. Apdo. Postal 510-3, Cuernavaca, Mor. 62250, Mexico.

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http://linkinghub.elsevier.com/retrieve/pii/S109671761200077
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September 2012

Metabolite profiling of CHO cells with different growth characteristics.

Biotechnol Bioeng 2012 Jun 30;109(6):1404-14. Epub 2012 Mar 30.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia.

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June 2012