Publications by authors named "Lars Jakobsson"

30Publications

Oncogenes in Brain Arteriovenous Malformations.

Circ Res 2020 Aug 27;127(6):744-746. Epub 2020 Aug 27.

From the Karolinska Institutet, Tomtebodavägen, Solna, Sweden (L.J.).

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http://dx.doi.org/10.1161/CIRCRESAHA.120.317722DOI Listing
August 2020

Loss of Endothelial Endoglin Promotes High-Output Heart Failure Through Peripheral Arteriovenous Shunting Driven by VEGF Signaling.

Circ Res 2020 01 6;126(2):243-257. Epub 2019 Dec 6.

From the Biosciences Institute (S.T.-C., R.E.R., E.S., B.D., C.P., H.L., H.M.A.), Faculty of Medical Sciences, Newcastle University, United Kingdom.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970547PMC
January 2020

Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea.

Sci Rep 2018 Jul 13;8(1):10672. Epub 2018 Jul 13.

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Solnavägen 9, SE171 65, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-018-28770-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045577PMC
July 2018

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity.

Development 2017 10 29;144(19):3590-3601. Epub 2017 Aug 29.

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Scheeles Väg 2, SE171 77 Stockholm, Sweden

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http://dx.doi.org/10.1242/dev.147967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665477PMC
October 2017

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.

Nat Cell Biol 2017 Jun 22;19(6):639-652. Epub 2017 May 22.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles väg 2, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1038/ncb3534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467724PMC
June 2017

Neuropilin 1 binds PDGF-D and is a co-receptor in PDGF-D-PDGFRβ signaling.

J Cell Sci 2017 04 2;130(8):1365-1378. Epub 2017 Mar 2.

Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Karolinska Institutet, Scheeles väg 2, A3:P4, Stockholm S-17177, Sweden.

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http://dx.doi.org/10.1242/jcs.200493DOI Listing
April 2017

RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms.

Sci Signal 2016 07 26;9(438):ra76. Epub 2016 Jul 26.

Cardeza Foundation for Hematologic Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1126/scisignal.aaf0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241026PMC
July 2016

VEGF, Notch and TGFβ/BMPs in regulation of sprouting angiogenesis and vascular patterning.

Biochem Soc Trans 2014 Dec;42(6):1576-83

*Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles väg 2, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1042/BST20140231DOI Listing
December 2014

The hippocampal neurovascular niche during normal development and after irradiation to the juvenile mouse brain.

Int J Radiat Biol 2014 Sep 26;90(9):778-89. Epub 2014 Aug 26.

Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg.

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http://www.tandfonline.com/doi/full/10.3109/09553002.2014.93
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http://dx.doi.org/10.3109/09553002.2014.931612DOI Listing
September 2014

Transforming growth factor β family members in regulation of vascular function: in the light of vascular conditional knockouts.

Exp Cell Res 2013 May 27;319(9):1264-70. Epub 2013 Feb 27.

Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2013.02.015DOI Listing
May 2013

The use of bathymetric data in society and science: a review from the Baltic Sea.

Ambio 2012 Mar 4;41(2):138-50. Epub 2011 Oct 4.

Department of Geological Sciences, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s13280-011-0192-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357835PMC
March 2012

The dynamics of developmental and tumor angiogenesis-a comparison.

Cancers (Basel) 2012 Apr 11;4(2):400-19. Epub 2012 Apr 11.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm SE-17177, Sweden.

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http://dx.doi.org/10.3390/cancers4020400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712694PMC
April 2012

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

Nat Cell Biol 2011 Sep 11;13(10):1202-13. Epub 2011 Sep 11.

Molecular/Cancer Biology Laboratory, Institute for Molecular Medicine Finland, Research Programs Unit and Department of Pathology, Haartman Institute, Biomedicum Helsinki, PO Box 63 (Haartmaninkatu 8), 00014 University of Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261765PMC
http://dx.doi.org/10.1038/ncb2331DOI Listing
September 2011

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.

Nat Cell Biol 2010 Oct 26;12(10):943-53. Epub 2010 Sep 26.

Vascular Biology Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

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http://pbsb.med.cornell.edu/pdfs/nature_jakobsson.pdf
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http://www.nature.com/doifinder/10.1038/ncb2103
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http://dx.doi.org/10.1038/ncb2103DOI Listing
October 2010

VEGFRs and Notch: a dynamic collaboration in vascular patterning.

Biochem Soc Trans 2009 Dec;37(Pt 6):1233-6

Vascular Biology Laboratory, London Research Institute - Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1042/BST0371233DOI Listing
December 2009

VEGFRs and Notch: a dynamic collaboration in vascular patterning.

Biochem Soc Trans 2009 Dec;37(Pt 6):1233-6

Vascular Biology Laboratory, London Research Institute - Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1042/BST0371233DOI Listing
December 2009

Vascular basement membrane components in angiogenesis--an act of balance.

ScientificWorldJournal 2008 Dec 14;8:1246-9. Epub 2008 Dec 14.

Vascular Biology Laboratory, London Research Institute, Cancer Research UK, London, UK.

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http://dx.doi.org/10.1100/tsw.2008.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848701PMC
December 2008

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow.

FASEB J 2008 May 11;22(5):1530-9. Epub 2007 Dec 11.

Department of Genetics and Pathology, Uppsala University, Dag Hammarskjöldsv 20, SE-75185, Uppsala, Sweden.

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http://www.fasebj.org/doi/10.1096/fj.07-9617com
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http://dx.doi.org/10.1096/fj.07-9617comDOI Listing
May 2008

Building blood vessels--stem cell models in vascular biology.

J Cell Biol 2007 Jun 29;177(5):751-5. Epub 2007 May 29.

Department of Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1083/jcb.200701146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064276PMC
June 2007

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation.

Blood 2006 Sep 11;108(6):1877-86. Epub 2006 May 11.

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsv. 20, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1182/blood-2006-04-014894DOI Listing
September 2006

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis.

Dev Cell 2006 May;10(5):625-34

Department of Genetics and Pathology, Uppsala University, Rudbeck Laboratory, Dag Hammarskjöldsv. 20, SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.devcel.2006.03.009DOI Listing
May 2006

Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.

J Biol Chem 2005 Dec 20;280(51):42397-404. Epub 2005 Oct 20.

Department of Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, S-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1074/jbc.M506724200DOI Listing
December 2005

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development.

Arterioscler Thromb Vasc Biol 2005 May 17;25(5):944-9. Epub 2005 Mar 17.

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1161/01.ATV.0000163182.73190.f9DOI Listing
May 2005

Laminin-1 promotes angiogenesis in synergy with fibroblast growth factor by distinct regulation of the gene and protein expression profile in endothelial cells.

J Biol Chem 2004 May 25;279(22):23766-72. Epub 2004 Mar 25.

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsvaüg 20, S-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1074/jbc.M311675200DOI Listing
May 2004

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development.

J Cell Sci 2004 Mar;117(Pt 8):1513-23

Department of Genetics and Pathology, Uppsala University, Rudbeck Laboratory, Dag Hammarskjöldsv. 20, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1242/jcs.00999DOI Listing
March 2004