Publications by authors named "Lars Frings"

58Publications

[123I]FP-CIT SPECT in Clinically Uncertain Parkinsonism Predicts Survival: A Data-Driven Analysis.

J Parkinsons Dis 2020 Oct 5. Epub 2020 Oct 5.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JPD-202214DOI Listing
October 2020

Automated voxel- and region-based analysis of gray matter and cerebrospinal fluid space in primary dementia disorders.

Brain Res 2020 Jul 22;1739:146800. Epub 2020 Mar 22.

Department of Neuroradiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Straße 64, 79106 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2020.146800DOI Listing
July 2020

Nigrostriatal Degeneration in the Cognitive Part of the Striatum in Parkinson Disease Is Associated With Frontomedial Hypometabolism.

Clin Nucl Med 2020 Feb;45(2):95-99

From the Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg-Eppendorf, Hamburg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002869DOI Listing
February 2020

Predictive Value of F-Florbetapir and F-FDG PET for Conversion from Mild Cognitive Impairment to Alzheimer Dementia.

J Nucl Med 2020 04 18;61(4):597-603. Epub 2019 Oct 18.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.119.230797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198373PMC
April 2020

F-FDG PET Imaging of the Inferior Colliculus in Asymmetric Hearing Loss.

J Nucl Med 2020 03 3;61(3):418-422. Epub 2019 Sep 3.

Department of Nuclear Medicine, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.119.231407DOI Listing
March 2020

Imaging cardiac sympathetic innervation with MIBG: linear conversion of the heart-to-mediastinum ratio between different collimators.

EJNMMI Phys 2019 Jul 23;6(1):12. Epub 2019 Jul 23.

Department of Nuclear Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg im Breisgau, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40658-019-0250-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650508PMC
July 2019

Limits for Reduction of Acquisition Time and Administered Activity in F-FDG PET Studies of Alzheimer Dementia and Frontotemporal Dementia.

J Nucl Med 2019 12 26;60(12):1764-1770. Epub 2019 Apr 26.

Department of Nuclear Medicine, Medical Center-University of Freiburg, Freiburg, Germany; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.119.227132DOI Listing
December 2019

Chorea-Acanthocytosis Presenting as Autosomal Recessive Epilepsy in a Family With a Novel Mutation.

Front Neurol 2018 9;9:1168. Epub 2019 Jan 9.

Department of Neurology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2018.01168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334619PMC
January 2019

Prognosis of conversion of mild cognitive impairment to Alzheimer's dementia by voxel-wise Cox regression based on FDG PET data.

Neuroimage Clin 2019 10;21:101637. Epub 2018 Dec 10.

Department of Nuclear Medicine, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany; Center for Geriatrics and Gerontology Freiburg, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2018.101637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411907PMC
December 2019

Principal Components Analysis of Brain Metabolism Predicts Development of Alzheimer Dementia.

J Nucl Med 2019 06 2;60(6):837-843. Epub 2018 Nov 2.

Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.118.219097DOI Listing
June 2019

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 11;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

Amyloid imaging for differential diagnosis of dementia: incremental value compared to clinical diagnosis and [F]FDG PET.

Eur J Nucl Med Mol Imaging 2019 02 10;46(2):312-323. Epub 2018 Aug 10.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-018-4111-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333717PMC
February 2019

Regional neuronal activity in patients with relapsing remitting multiple sclerosis.

Acta Neurol Scand 2018 Dec 4;138(6):466-474. Epub 2018 Sep 4.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ane.13012DOI Listing
December 2018

Do all visual deficits cause pure alexia? Dissociations between visual processing and reading suggest "no".

Brain Cogn 2018 08 11;125:69-77. Epub 2018 Jun 11.

Klinik für Neurologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Germany; Zentrum für Geriatrie und Gerontologie (ZGG), Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Germany; Freiburg Brain Imaging, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Germany; "BrainLinks BrainTools" Exzellenzcluster, Albert-Ludwigs-Universität Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bandc.2018.05.008DOI Listing
August 2018

Amyloid load but not regional glucose metabolism predicts conversion to Alzheimer's dementia in a memory clinic population.

Eur J Nucl Med Mol Imaging 2018 07 15;45(8):1442-1448. Epub 2018 Mar 15.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-018-3983-6DOI Listing
July 2018

Antidepressant treatment effects on dopamine transporter availability in patients with major depression: a prospective I-FP-CIT SPECT imaging genetic study.

J Neural Transm (Vienna) 2018 06 23;125(6):995-1005. Epub 2018 Feb 23.

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00702-018-1863-7DOI Listing
June 2018

Ataxia and autonomic dysfunction as presenting symptoms in late-onset Alexander disease.

Neurol Clin Pract 2017 Dec;7(6):523-526

Freiburg University Medical Center and Medical Faculty, Freiburg University, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/CPJ.0000000000000392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800710PMC
December 2017

F-FDG PET in Parkinsonism: Differential Diagnosis and Evaluation of Cognitive Impairment.

J Nucl Med 2017 12 14;58(12):1888-1898. Epub 2017 Sep 14.

Department of Psychiatry, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.116.186403DOI Listing
December 2017

Radioiodine therapy of benign thyroid-disorders.

Nuklearmedizin 2017 4;56(5):171-176. Epub 2018 Jan 4.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3413/Nukmed-0875-17-01DOI Listing
November 2018

Novel compound heterozygous synaptojanin-1 mutation causes l-dopa-responsive dystonia-parkinsonism syndrome.

Mov Disord 2017 03 21;32(3):478-480. Epub 2016 Nov 21.

Department of Neurology, Freiburg University Medical Center and Medical Faculty, Freiburg University, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mds.26876DOI Listing
March 2017

Left Anterior Temporal Glucose Metabolism and not Amyloid-beta Load Predicts Naming Impairment in Alzheimer's Disease.

Curr Alzheimer Res 2016 ;13(6):678-81

Zentrum für Geriatrie und Gerontologie, Universitätsklinikum Freiburg, Lehener Str. 88, 79106 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1567205013666160322141955DOI Listing
January 2017

Optimization of Statistical Single Subject Analysis of Brain FDG PET for the Prognosis of Mild Cognitive Impairment-to-Alzheimer's Disease Conversion.

J Alzheimers Dis 2016 ;49(4):945-959

Department of Nuclear Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-150814DOI Listing
October 2016

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice.

Brain Behav Immun 2016 07 11;55:126-137. Epub 2015 Nov 11.

Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany; Department for Neuroscience, University Medical Center Groningen, University of Groningen, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbi.2015.11.008DOI Listing
July 2016

Asymmetries of amyloid-β burden and neuronal dysfunction are positively correlated in Alzheimer's disease.

Brain 2015 Oct 13;138(Pt 10):3089-99. Epub 2015 Aug 13.

1 Department of Nuclear Medicine, University Medical Centre, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awv229DOI Listing
October 2015

18F-FDG PET Is an Early Predictor of Overall Survival in Suspected Atypical Parkinsonism.

J Nucl Med 2015 Oct 30;56(10):1541-6. Epub 2015 Jul 30.

Department of Nuclear Medicine, University Hospital of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.115.159822DOI Listing
October 2015

Incipient preoperative reorganization processes of verbal memory functions in patients with left temporal lobe epilepsy.

Epilepsy Behav 2015 Jan 11;42:78-85. Epub 2014 Dec 11.

Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2014.11.026DOI Listing
January 2015

Role of semiquantitative assessment of regional binding potential in 123I-FP-CIT SPECT for the differentiation of frontotemporal dementia, dementia with Lewy bodies, and Alzheimer's dementia.

Clin Nucl Med 2015 Jan;40(1):e27-33

From the *Department of Nuclear Medicine, †Centre of Geriatrics and Gerontology, Departments of ‡Radiation Oncology, §Psychiatry and Psychotherapy, and ¶Neurology, University Hospital Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://pdfs.journals.lww.com/nuclearmed/2015/01000/Role_of_S
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/RLU.0000000000000554DOI Listing
January 2015

Update on SPECT and PET in parkinsonism - part 2: biomarker imaging of cognitive impairment in Lewy-body diseases.

Curr Opin Neurol 2014 Aug;27(4):398-404

aDepartment of Nuclear Medicine bCentre of Geriatrics and Gerontology cDepartment of Neurology dDepartment of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WCO.0000000000000107DOI Listing
August 2014

Longitudinal grey and white matter changes in frontotemporal dementia and Alzheimer's disease.

PLoS One 2014 3;9(3):e90814. Epub 2014 Mar 3.

Neuroscience Research Australia, Sydney, Australia; ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia; School of Medical Sciences, University of New South Wales, Sydney, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940927PMC
November 2014

Neural correlates of cognitive dysfunction in Lewy body diseases and tauopathies: combined assessment with FDG-PET and the CERAD test battery.

Brain Lang 2013 Nov 31;127(2):307-14. Epub 2013 Oct 31.

Department of Neurology, University Hospital Freiburg, Freiburg, Germany; Department of Psychiatry, University Hospital Freiburg, Freiburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bandl.2013.10.004DOI Listing
November 2013

Longitudinal cerebral diffusion changes reflect progressive decline of language and cognition.

Psychiatry Res 2013 Dec 18;214(3):395-401. Epub 2013 Oct 18.

Center of Geriatrics and Gerontology Freiburg, University Medical Center, University of Freiburg, Germany; Section of Geriatric Psychiatry and Neuropsychology, University Medical Center, University of Freiburg, Germany; Department of Radiation Oncology, University Medical Center, University of Freiburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pscychresns.2013.08.003DOI Listing
December 2013

Amyloid-β load predicts medial temporal lobe dysfunction in Alzheimer dementia.

J Nucl Med 2013 Nov 7;54(11):1909-14. Epub 2013 Oct 7.

Center of Geriatrics and Gerontology Freiburg, University Hospital Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.113.120378DOI Listing
November 2013

Nonlinear correlations impair quantification of episodic memory by mesial temporal BOLD activity.

Neuropsychology 2013 Jul;27(4):402-16

Department of Neurology and Epileptology, University of Tuebingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1037/a0032709DOI Listing
July 2013

Alterations in functional connectivity of the amygdala in unilateral mesial temporal lobe epilepsy.

J Neurol 2012 Dec 12;259(12):2546-54. Epub 2012 Jun 12.

Swiss Epilepsy Centre, Bleulerstrasse 60, 8008 Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-012-6533-3DOI Listing
December 2012

Quantifying change in individual subjects affected by frontotemporal lobar degeneration using automated longitudinal MRI volumetry.

Hum Brain Mapp 2012 Jul 26;33(7):1526-35. Epub 2011 May 26.

Department of Psychiatry and Psychotherapy, Center of Geriatrics and Gerontology Freiburg, Freiburg Brain Imaging, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.21304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869947PMC
July 2012

A comparison of different automated methods for the detection of white matter lesions in MRI data.

Neuroimage 2011 Jul 3;57(2):416-22. Epub 2011 May 3.

Department of Psychiatry and Psychotherapy, Section for Gerontopsychiatry, University Medical Center Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2011.04.053DOI Listing
July 2011

Watching TV news as a memory task--brain activation and age effects.

BMC Neurosci 2010 Aug 26;11:106. Epub 2010 Aug 26.

Section of Gerontopsychiatry and Neuropsychology, Medical School, Albert-Ludwigs-University Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2202-11-106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939655PMC
August 2010

Remote effects of hippocampal damage on default network connectivity in the human brain.

J Neurol 2009 Dec 15;256(12):2021-9. Epub 2009 Jul 15.

Epilepsy Center, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00415-009-5233-0
Publisher Site
http://dx.doi.org/10.1007/s00415-009-5233-0DOI Listing
December 2009

Reduced interhemispheric hippocampal BOLD signal coupling related to early epilepsy onset.

Seizure 2009 Mar;18(2):153-7

Epilepsy Center, University of Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.seizure.2008.06.015DOI Listing
March 2009

Early detection of behavioral side effects of antiepileptic treatment using handheld computers.

Epilepsy Behav 2008 Aug 6;13(2):402-6. Epub 2008 Jun 6.

Epilepsy Center, University Hospital of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2008.04.022DOI Listing
August 2008

Hippocampal functional connectivity reflects verbal episodic memory network integrity.

Neuroreport 2007 Oct;18(16):1719-23

Epilepsy Center, University Hospital Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WNR.0b013e3282f0d3c5DOI Listing
October 2007

The influence of antiepileptic drugs on cognition: a comparison of levetiracetam with topiramate.

Epilepsy Behav 2007 May 3;10(3):486-94. Epub 2007 Apr 3.

Epilepsy Centre, Neurocentre, University Hospital Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2007.02.007DOI Listing
May 2007

Precuneus is involved in allocentric spatial location encoding and recognition.

Exp Brain Res 2006 Sep 9;173(4):661-72. Epub 2006 Mar 9.

Epilepsy Center, University Hospital of Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00221-006-0408-8DOI Listing
September 2006

Gender-related differences in lateralization of hippocampal activation and cognitive strategy.

Neuroreport 2006 Mar;17(4):417-21

Epilepsy Centre, University Hospital of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.wnr.0000203623.02082.e3DOI Listing
March 2006