Larry Norton

Larry Norton

UNVERIFIED PROFILE

Are you Larry Norton?   Register this Author

Register author
Larry Norton

Larry Norton

Publications by authors named "Larry Norton"

Are you Larry Norton?   Register this Author

100Publications

3666Reads

15Profile Views

Multisystem Toxicity in Cancer: Lessons from NASA's Countermeasures Program.

Cell 2019 Nov;179(5):1003-1009

Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.10.024DOI Listing
November 2019

A Tribute to John Mendelsohn: A Pioneer in Targeted Cancer Therapy.

Cancer Res 2019 Sep 18;79(17):4315-4323. Epub 2019 Jun 18.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-19-0989DOI Listing
September 2019

p21CIP1 Promotes Mammary Cancer-Initiating Cells via Activation of Wnt/TCF1/CyclinD1 Signaling.

Mol Cancer Res 2019 07 9;17(7):1571-1581. Epub 2019 Apr 9.

Department of Pathology, Albert Einstein College of Medicine, Bronx, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-18-1044DOI Listing
July 2019

Supporting data sharing.

NPJ Breast Cancer 2019 13;5. Epub 2019 Feb 13.

2Memorial Sloan-Kettering Cancer Center, New York, NY USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41523-019-0103-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374458PMC
February 2019

Reply to "Multicentric Ipsilateral Invasive Breast Carcinomas Might Have Higher 21-Gene Recurrence Score Compared with Multifocal Ipsilateral Invasive Breast Carcinomas".

Ann Surg Oncol 2019 01 19;26(1):310-311. Epub 2018 Nov 19.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-018-7078-1DOI Listing
January 2019

Phase II Study of Paclitaxel and Dasatinib in Metastatic Breast Cancer.

Clin Breast Cancer 2018 10 15;18(5):387-394. Epub 2018 Mar 15.

Breast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clbc.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682312PMC
October 2018

Sleep problems in breast cancer survivors 1-10 years posttreatment.

Palliat Support Care 2018 06 16;16(3):325-334. Epub 2017 May 16.

National Sleep Research Institute,New York,New York,USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1478951517000311DOI Listing
June 2018

The 21-Gene Recurrence Score in Male Breast Cancer.

Ann Surg Oncol 2018 Jun 8;25(6):1530-1535. Epub 2018 Mar 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-018-6411-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930124PMC
June 2018

Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact.

Breast Cancer Res Treat 2018 01 6;167(2):547-554. Epub 2017 Oct 6.

Cedars-Sinai Medical Center, 8700 Beverly Blvd, AC 1042B, Los Angeles, CA, 90048, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-017-4520-1DOI Listing
January 2018

Breast carcinoma with 21-gene recurrence score lower than 18: rate of locoregional recurrence in a large series with clinical follow-up.

BMC Cancer 2018 01 6;18(1):42. Epub 2018 Jan 6.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-017-3985-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756373PMC
January 2018

21-Gene recurrence score and locoregional recurrence in lymph node-negative, estrogen receptor-positive breast cancer.

Breast Cancer Res Treat 2017 Nov 12;166(1):69-76. Epub 2017 Jul 12.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-017-4381-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647226PMC
November 2017

The 21-gene recurrence score in special histologic subtypes of breast cancer with favorable prognosis.

Breast Cancer Res Treat 2017 Aug 3;165(1):65-76. Epub 2017 Jun 3.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-017-4326-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572649PMC
August 2017

American Society of Clinical Oncology Position Statement: Strategies for Reducing Cancer Health Disparities Among Sexual and Gender Minority Populations.

J Clin Oncol 2017 Jul 3;35(19):2203-2208. Epub 2017 Apr 3.

Jennifer Griggs, University of Michigan, Ann Arbor, MI; Shail Maingi, New Jersey Medical School-University Hospital Cancer Center, Newark, NJ; Victoria Blinder and Larry Norton, Memorial Sloan Kettering Cancer Center, New York, NY; Neelima Denduluri, US Oncology, The Woodlands, TX; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Michael Francisco and Dana S. Wollins, American Society of Clinical Oncology, Alexandria, VA; and Julia H. Rowland, National Cancer Institute, Bethesda, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.72.0441DOI Listing
July 2017

A Rare Case of S310F Somatic ERBB2 Mutation in a HER2-Nonamplified Breast Cancer.

Clin Breast Cancer 2017 02 18;17(1):e37-e41. Epub 2016 Aug 18.

Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clbc.2016.08.001DOI Listing
February 2017

Dealing with the tyranny of certainty in the (medical) digital age.

Authors:
Larry Norton

Psychooncology 2017 02;26(2):147-148

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pon.4381DOI Listing
February 2017

Prognostic Impact of 21-Gene Recurrence Score in Patients With Stage IV Breast Cancer: TBCRC 013.

J Clin Oncol 2016 07 21;34(20):2359-65. Epub 2016 Mar 21.

Tari A. King, Jaclyn P. Lyman, Mithat Gonen, Amy Voci, Marina De Brot, Camilla Boafo, Larry Norton, Monica Morrow, and Clifford A. Hudis, Memorial Sloan Kettering Cancer Center, New York, NY; Amy Pratt Sing, Genomic Health, Redwood City; Michael D. Alvarado, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA; E. Shelley Hwang, Duke University School of Medicine, Durham, NC; Minetta C. Liu, Georgetown University Medical Center, Washington, DC; Judy C. Boughey, Mayo Clinic, Rochester, MN; Kandace P. McGuire, University of Pittsburgh, Pittsburgh, PA; Catherine H. Van Poznak, University of Michigan Medical School, Ann Arbor, MI; Lisa K. Jacobs, Johns Hopkins University School of Medicine, Baltimore, MD; Ingrid M. Meszoely, Vanderbilt University Medical Center, Nashville, TN; Helen Krontiras, University of Alabama at Birmingham School of Medicine, Birmingham, AL; and Gildy V. Babiera, The University of Texas MD Anderson Cancer Center, Houston, TX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.63.1960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981976PMC
July 2016

Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia.

Breast Cancer Res Treat 2016 06 5;157(2):395-400. Epub 2016 May 5.

Dermatology Service, Memorial Sloan Kettering Cancer Center, 60th Street Outpatient Center, 16 East 60th St., Suite 407, Room 4312, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-016-3799-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612426PMC
June 2016

TNF is a key cytokine mediating neutrophil cytotoxic activity in breast cancer patients.

NPJ Breast Cancer 2016 20;2:16009. Epub 2016 Apr 20.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjbcancer.2016.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515342PMC
April 2016

Decreased gastrointestinal toxicity associated with a novel capecitabine schedule (7 days on and 7 days off): a systematic review.

NPJ Breast Cancer 2016 30;2:16006. Epub 2016 Mar 30.

Breast Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjbcancer.2016.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515341PMC
March 2016

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Genes Dev 2016 Jan 23;30(1):34-51. Epub 2015 Dec 23.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, New York 11790, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.270959.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701977PMC
January 2016

Cancer log-kill revisited.

Authors:
Larry Norton

Am Soc Clin Oncol Educ Book 2014 :3-7

From the Memorial Sloan Kettering Cancer Center, New York, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14694/EdBook_AM.2014.34.3DOI Listing
November 2015

Cell-to-cell communication in cancer: workshop report.

NPJ Breast Cancer 2015 25;1:15022. Epub 2015 Nov 25.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjbcancer.2015.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515200PMC
November 2015

Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites.

NPJ Breast Cancer 2015 21;1:15018. Epub 2015 Oct 21.

Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjbcancer.2015.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515198PMC
October 2015

Current management of lesions associated with an increased risk of breast cancer.

Nat Rev Clin Oncol 2015 Apr 27;12(4):227-38. Epub 2015 Jan 27.

Breast Cancer Medicine Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

View Article

Download full-text PDF

Source
http://assets.krebsliga.ch/downloads/current_management_of_l
Web Search
http://www.nature.com/doifinder/10.1038/nrclinonc.2015.8
Publisher Site
http://dx.doi.org/10.1038/nrclinonc.2015.8DOI Listing
April 2015

Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .

Mod Pathol 2015 Mar 21;28(3):340-51. Epub 2014 Nov 21.

1] Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA [2] Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2014.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523239PMC
March 2015

The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study.

J Natl Cancer Inst 2014 Sep 4;106(9). Epub 2014 Sep 4.

Department of Medicine (MS, AD, LR, JB, LN) and Department of Pathology (RC, JRF, WG) and Department of Surgery (HC) and Department of Computational Biology (RK), Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College (MS, JRF, WG, HC, JB, LN).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/dju189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817128PMC
September 2014

Comparison of doxorubicin and cyclophosphamide versus single-agent paclitaxel as adjuvant therapy for breast cancer in women with 0 to 3 positive axillary nodes: CALGB 40101 (Alliance).

J Clin Oncol 2014 Aug 16;32(22):2311-7. Epub 2014 Jun 16.

Lawrence N. Shulman, Harold J. Burstein, Eric P. Winer, Dana-Farber Cancer Institute, Boston, MA; Donald A. Berry, MD Anderson Cancer Center, Houston, TX; Constance T. Cirrincione, Gretchen Kimmick, Duke University Medical Center, Durham; Hyman Muss, University of North Carolina at Chapel Hill, Chapel Hill, NC; Heather P. Becker, University of Chicago, Chicago, IL; Edith A. Perez, Mayo Clinic, Jacksonville, FL; Ruth O'Regan, Emory University, Atlanta, GA; Silvana Martino, The Angeles Clinic and Research Institute, Los Angeles, CA; Charles L. Shapiro, The James Cancer Center, Ohio State University, Columbus, OH; Charles J. Schneider, Christiana Healthcare Services, Wilmington, DE; Larry Norton, Clifford A. Hudis, Memorial Sloan-Kettering Cancer Center, New York, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.53.7142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105484PMC
August 2014

Advances in managing breast cancer: a clinical update.

F1000Prime Rep 2014 1;6:66. Epub 2014 Aug 1.

Breast Cancer Medicine Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York, NY10065, USA ; Department of Medicine Weill Cornell Medical College New York, NY 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12703/P6-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126526PMC
August 2014

Association between bone mineral density and incidence of breast cancer.

PLoS One 2013 5;8(8):e70980. Epub 2013 Aug 5.

Endocrine Unit, Columbia University Medical Center, New York, New York, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070980PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733715PMC
March 2014

TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition.

Cell Rep 2013 Dec;5(5):1228-42

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, 415 East 68(th) Street, New York, NY 10065, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2013.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891470PMC
December 2013

Living with metastatic breast cancer: a qualitative analysis of physical, psychological, and social sequelae.

Breast J 2013 May-Jun;19(3):285-92. Epub 2013 Mar 26.

Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tbj.12107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097181PMC
November 2013

Acquired resistance to crizotinib from a mutation in CD74-ROS1.

N Engl J Med 2013 09;369(12):1172-3

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1309091DOI Listing
September 2013

Epoetin alfa: to give or not to give.

J Natl Cancer Inst 2013 Jul 16;105(14):1001-3. Epub 2013 Jul 16.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djt172DOI Listing
July 2013

Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model.

Cancer Res 2013 May 27;73(9):2760-9. Epub 2013 Feb 27.

Department of Aerospace & Mechanical Engineering, Viterbi School of Engineering, University of Southern California, Los Angles 90089, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-12-4488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644026PMC
May 2013

Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer.

J Mammary Gland Biol Neoplasia 2012 Dec 26;17(3-4):241-9. Epub 2012 Sep 26.

Department of Medicine, Memorial Sloan-Kettering Cancer Center and the Weill College of Medicine of Cornell University, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10911-012-9267-z
Publisher Site
http://dx.doi.org/10.1007/s10911-012-9267-zDOI Listing
December 2012

DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors.

Am J Surg Pathol 2012 Nov;36(11):1700-8

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAS.0b013e3182627787DOI Listing
November 2012