Larry Moreland

Larry Moreland

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Larry Moreland

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Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis.

J Rheumatol 2019 Sep 1. Epub 2019 Sep 1.

From Boston University, Boston, MA, USA; University of Arizona, Tucson, AZ, USA; University of Michigan, Ann Arbor, MI, USA; University of South Florida, Tampa, FL, USA; Mount Sinai Hospital, Toronto, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada; University of Utah, Salt Lake City, UT, USA; Cleveland Clinic, Cleveland, OH, USA; University of Pennsylvania, Philadelphia, PA, USA; University of Pittsburgh, Pittsburgh, PA, USA; Johns Hopkins University, Baltimore, MD, USA; Mayo Clinic, Rochester, MN, USA; VA Boston Healthcare System, Boston, MA, USA. This work was sponsored by the Vasculitis Clinical Research Consortium. The Vasculitis Clinical Research Consortium (VCRC) is part of the Rare Diseases Clinical Research Network (RDCRN), an initiative of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Science (NCATS). The VCRC is funded through collaboration between NCATS, and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), U54 AR057319), and has received funding from the National Center for Research Resources (U54 RR019497). Additional funding for this project included RC1 AR 058303 and P60 AR047785. Dr. Merkel reports receiving funds for the following activities: Consulting: AbbVie, AstraZeneca, Biogen, Boeringher-Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, Genzyme/Sanofi, GlaxoSmithKline, InflaRx, Insmed, Jannsen, Kiniksa; Research Support: AstraZeneca, Boeringher- Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, GlaxoSmithKline, Kypha, TerumoBCT; Royalties: UpToDate. Dr. Monach reports receiving funds for the following activities: Consulting: Celgene, ChemoCentryx. Address correspondence to Paul Monach, MD, PhD Rheumatology Section VA Boston Healthcare System 150 South Huntington Ave Boston, MA 02130. Email:

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http://dx.doi.org/10.3899/jrheum.190093DOI Listing
September 2019

Contraception Use Among Reproductive-Age Women With Rheumatic Diseases.

Arthritis Care Res (Hoboken) 2019 Aug 3;71(8):1132-1140. Epub 2019 Jul 3.

University of Pittsburgh and Center for Health Equity Research and Promotion, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.

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http://doi.wiley.com/10.1002/acr.23724
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http://dx.doi.org/10.1002/acr.23724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375807PMC
August 2019

Feasibility and Construct Validation of the Patient Reported Outcomes Measurement Information System in Systemic Vasculitis.

J Rheumatol 2019 Aug 1;46(8):928-934. Epub 2019 Mar 1.

From the Department of Epidemiology and Biostatistics, Faculty of Medicine, University of Iceland; Department of Rheumatology, and Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland; Department of Biostatistics, Epidemiology, and Informatics, and Division of Rheumatology, and Department of Family Medicine and Community Health, and Division of General Internal Medicine, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, Florida; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Department of Rheumatology, Cleveland Clinic, Cleveland; Ohio State University Wexner Medical Center, Columbus, Ohio; Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, and Division of Pulmonology and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Nuffield Department of Population Health, Health Services Research Unit (HSRU), and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford; Faculty of Health and Applied Sciences, University of the West of England, Bristol and School of Clinical Sciences, University of Bristol, Bristol, UK; Department of Rheumatology, University of Ottawa, Ottawa; Division of Rheumatology, Mount Sinai Hospital, Toronto; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.171405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726391PMC
August 2019

Inflammatory joint diseases and atherosclerosis: time to look beyond the 'lipid paradox'.

Curr Opin Lipidol 2019 Aug;30(4):342-349

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOL.0000000000000620DOI Listing
August 2019

Update on Cardiovascular Disease Risk in Patients with Rheumatic Diseases.

Rheum Dis Clin North Am 2018 Aug 12;44(3):475-487. Epub 2018 Jun 12.

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Thomas E. Starzl Biomedical Science Tower South 711, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.rdc.2018.03.006DOI Listing
August 2018

14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in T2 and CD8 lymphocytes from patients with scleroderma.

J Allergy Clin Immunol 2018 07 15;142(1):109-119.e6. Epub 2017 Nov 15.

Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953767PMC
July 2018

Family Planning Counseling for Women With Rheumatic Diseases.

Arthritis Care Res (Hoboken) 2018 02;70(2):169-174

Veteran's Affairs Pittsburgh Center for Health Equity Research and Promotion, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/acr.23267DOI Listing
February 2018

Cardiovascular Disease Risk in Patients with Rheumatic Diseases.

Clin Geriatr Med 2017 02;33(1):105-117

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Thomas E. Starzl Biomedical Science Tower South 711, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.cger.2016.08.008DOI Listing
February 2017

Improvement in Herpes Zoster Vaccination in Patients with Rheumatoid Arthritis: A Quality Improvement Project.

J Rheumatol 2017 01 15;44(1):11-17. Epub 2016 Nov 15.

From the Department of Medicine, University of Pittsburgh School of Medicine, and Rheumatology Division, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.3899/jrheum.160179DOI Listing
January 2017

Cost-Effectiveness of Triple Therapy Versus Etanercept Plus Methotrexate in Early Aggressive Rheumatoid Arthritis.

Arthritis Care Res (Hoboken) 2016 12 21;68(12):1751-1757. Epub 2016 Oct 21.

University of Nebraska Medical Center, Omaha, and National Data Bank for Rheumatic Diseases, Wichita, Kansas.

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http://dx.doi.org/10.1002/acr.22895DOI Listing
December 2016

Analysis of CXCR5Th17 cells in relation to disease activity and TNF inhibitor therapy in Rheumatoid Arthritis.

Sci Rep 2016 12 22;6:39474. Epub 2016 Dec 22.

Division of Rheumatology, Department of Medicine, University of Pittsburgh, 3500 Terrace St, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1038/srep39474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177940PMC
December 2016

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

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http://dx.doi.org/10.1038/ncomms13205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062501PMC
October 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

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http://dx.doi.org/10.1038/ncomms12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996969PMC
August 2016

Vasculitis in patients with inflammatory bowel diseases: A study of 32 patients and systematic review of the literature.

Semin Arthritis Rheum 2016 Feb 26;45(4):475-82. Epub 2015 Jul 26.

Division of Rheumatology, Mount Sinai Hospital, University of Toronto, The Joseph and Wolf Lebovic Building, 60 Murray St, Ste 2-220, Toronto, Ontario, Canada M5T 3L9. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2015.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982464PMC
February 2016

Reply.

Arthritis Rheumatol 2016 Feb;68(2):555-6

University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1002/art.39471DOI Listing
February 2016

Cardiac Involvement in Granulomatosis with Polyangiitis.

J Rheumatol 2015 Jul 1;42(7):1209-12. Epub 2015 May 1.

From the Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Health Informatics Institute, University of South Florida, Tampa, Florida; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pennsylvania; The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Pulmonary and Critical Care Medicine, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.L. McGeoch, MD; S. Carette, MD, Division of Rheumatology, Mount Sinai Hospital; D. Cuthbertson, MS, Health Informatics Institute, University of South Florida; G.S. Hoffman, MD, Center for Vasculitis Care and Research, Cleveland Clinic; N. Khalidi, MD, Division of Rheumatology, McMaster University; C.L. Koening, MD, Division of Rheumatology, University of Utah; C.A. Langford, MD, Center for Vasculitis Care and Research, Cleveland Clinic; C.A. McAlear, MA, Division of Rheumatology, University of Pennsylvania; L. Moreland, MD, Division of Rheumatology, University of Pittsburgh; P.A. Monach, MD, PhD, The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine; P. Seo, MD, Division of Rheumatology, Johns Hopkins University; U. Specks, MD, Division of Pulmonary and Critical Care Medicine; S.R. Ytterberg, MD, Division of Rheumatology, Mayo Clinic College of Medicine; P.A. Merkel, MD, MPH, Division of Rheumatology, University of Pennsylvania; C. Pagnoux, MD, MSc, MPH, Division of Rheumatology, Mount Sinai Hospital.

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http://dx.doi.org/10.3899/jrheum.141513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505809PMC
July 2015

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.

Am J Hum Genet 2015 Apr 26;96(4):565-80. Epub 2015 Mar 26.

Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.

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http://dx.doi.org/10.1016/j.ajhg.2015.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385191PMC
April 2015

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.

PLoS One 2014 10;9(2):e87645. Epub 2014 Feb 10.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919745PMC
October 2014

Induction therapy with combination TNF inhibitor and methotrexate in early rheumatoid arthritis.

Curr Rheumatol Rep 2014 May;16(5):417

Division of Rheumatology and Clinical Immunology, University of Pittsburgh, S703 Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA, USA,

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http://dx.doi.org/10.1007/s11926-014-0417-8DOI Listing
May 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Nature 2014 Feb 25;506(7488):376-81. Epub 2013 Dec 25.

1] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944098PMC
February 2014

Comparison of the disease activity score using erythrocyte sedimentation rate and C-reactive protein in African Americans with rheumatoid arthritis.

J Rheumatol 2013 Nov 15;40(11):1812-22. Epub 2013 Aug 15.

From the University of Alabama at Birmingham, Birmingham, Alabama; Emory University, Atlanta, Georgia; The University of North Carolina, Chapel Hill, North Carolina; The Medical University of South Carolina, Charleston, South Carolina; Washington University at St. Louis, St. Louis, Missouri; The University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.3899/jrheum.121225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987124PMC
November 2013

Associations of alcohol use with radiographic disease progression in African Americans with recent-onset rheumatoid arthritis.

J Rheumatol 2013 Sep 15;40(9):1498-504. Epub 2013 Jun 15.

Departments of Medicine and Biostatistics, Omaha Veterans Affairs Medical Center (VAMC) and University of Nebraska Medical Center, Omaha, Nebraska 68198-6270, USA.

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http://dx.doi.org/10.3899/jrheum.121325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026220PMC
September 2013

JAK inhibition in rheumatoid arthritis.

Curr Rheumatol Rep 2011 Oct;13(5):379-80

Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1007/s11926-011-0196-4DOI Listing
October 2011

Inhibition of spleen tyrosine kinase for rheumatoid arthritis.

Curr Rheumatol Rep 2011 Oct;13(5):377-8

Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1007/s11926-011-0195-5DOI Listing
October 2011

Cost-effectiveness of biologics compared with disease-modifying antirheumatic drugs in rheumatoid arthritis.

Curr Rheumatol Rep 2011 Oct;13(5):381-2

Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1007/s11926-011-0197-3DOI Listing
October 2011

Certolizumab pegol: a new biologic targeting rheumatoid arthritis.

Expert Rev Clin Immunol 2010 Nov;6(6):855-66

Division of Rheumatology and Clinical Immunology, Division of Pediatric Rheumatology, University of Pittsburgh, Children's Hospital, Suite 3000, 400 45th Street, Pittsburgh, PA 15201, USA.

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http://dx.doi.org/10.1586/eci.10.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971417PMC
November 2010

Interleukin-6 inhibition for treatment of rheumatoid arthritis: a review of tocilizumab therapy.

Drug Des Devel Ther 2010 Oct 1;4:263-78. Epub 2010 Oct 1.

Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15201, USA.

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http://dx.doi.org/10.2147/DDDT.S14099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990387PMC
October 2010

Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis.

J Rheumatol 2010 Feb 23;37(2):275-81. Epub 2009 Dec 23.

University of Nebraska Medical Center, Nebraska Arthritis Outcomes Research Center (NAORC), Omaha Veterans Affairs Medical Center, Omaha, Nebraska 68198-6270, USA.

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http://dx.doi.org/10.3899/jrheum.090705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133625PMC
February 2010

Cytokines as targets for anti-inflammatory agents.

Authors:
Larry W Moreland

Ann N Y Acad Sci 2009 Dec;1182:88-96

University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05072.xDOI Listing
December 2009

Systemic nonarticular manifestations of rheumatoid arthritis: focus on inflammatory mechanisms.

Semin Arthritis Rheum 2009 Oct 3;39(2):132-43. Epub 2008 Dec 3.

University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.semarthrit.2008.08.003DOI Listing
October 2009

Methotrexate versus combination methotrexate and etanercept for rheumatoid arthritis.

Curr Rheumatol Rep 2009 Oct;11(5):309-10

Division of Rheumatology and Clinical Immunology, Division of Pediatric Rheumatology, University of Pittsburgh, Children's Hospital, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741098PMC
October 2009

Certolizumab pegol in active rheumatoid arthritis.

Curr Rheumatol Rep 2009 Oct;11(5):311-2

Division of Rheumatology and Clinical Immunology, Division of Pediatric Rheumatology, University of Pittsburgh, Children's Hospital, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741093PMC
October 2009

Tocilizumab versus methotrexate in moderate to severe rheumatoid arthritis.

Curr Rheumatol Rep 2009 Oct;11(5):313-4

Division of Rheumatology and Clinical Immunology, Division of Pediatric Rheumatology, University of Pittsburgh, Children's Hospital, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741095PMC
October 2009

The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis.

J Med Food 2009 Oct;12(5):1143-8

Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294-1270, USA.

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http://www.liebertpub.com/doi/10.1089/jmf.2008.0244
Publisher Site
http://dx.doi.org/10.1089/jmf.2008.0244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784890PMC
October 2009

Herpes simplex encephalitis during treatment with tumor necrosis factor-alpha inhibitors.

Clin Infect Dis 2009 Sep;49(6):924-7

Division of Infectious Diseases, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

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http://dx.doi.org/10.1086/605498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315107PMC
September 2009