Larry A Couture

Larry A Couture

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Larry A Couture

Larry A Couture

Publications by authors named "Larry A Couture"

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Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

Circulation 2017 May 6;135(19):1832-1847. Epub 2017 Feb 6.

From Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wettwer, W.-H.Z.); German Center for Cardiovascular Research (DZHK), partner site Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wingender, W.A.L., W.-H.Z.); Institute of Bioinformatics, University Medical Center Göttingen, Germany (S.Z., E. Wingender); Stanford Cardiovascular Institute (J.R., M.W., J.D.G., J.C.W.) and Department of Radiology (J.D.G., J.C.W.), Molecular Imaging Program, Stanford University School of Medicine, CA; The Sohnis Laboratory for Cardiac Electrophysiology and Regenerative Medicine, Technion-Israel Institute of Technology, Haifa (I.K., L.G.); Institute of Pharmacology and Toxicology, Technical University Dresden, Germany (E. Wettwer, U.R.); University Medical Center Utrecht and Hubrecht Institute, The Netherlands (P.D., L.W.v.L.); Leiden University Medical Center, The Netherlands (M.J.G.); Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Germany (S.K., K.T., G.H., W.A.L.); Center for Applied Technology, Beckman Research Institute, City of Hope, Duarte, CA (L.A.C.); Department of Cardiovascular Physiology, Institute of Physiology, Ruhr University Bochum, Bochum, Germany (A.U., W.A.L.); New Laura and Isaac Perlmutter Cancer Center at New York University Langone (T.A., B.N.); and McEwen Centre for Regenerative Medicine, Toronto, Canada (G.K.). The current address for Dr Hudson is Laboratory for Cardiac Regeneration, School of Biomedical Sciences, The University of Queensland, Australia.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501412PMC
May 2017

Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation "Memories".

EBioMedicine 2016 Feb 19;4:74-85. Epub 2016 Jan 19.

Department of Diabetes Complications and Metabolism, Duarte, CA 91010, USA; Beckman Research Institute at City of Hope National Medical Center, Duarte, CA 91010, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964163001
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http://dx.doi.org/10.1016/j.ebiom.2016.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776252PMC
February 2016

The suspension culture of undifferentiated human pluripotent stem cells using spinner flasks.

Methods Mol Biol 2015 ;1283:13-21

Center for Applied Technology Development, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1007/7651_2014_118DOI Listing
November 2015

2005 Donor Eligibility Requirements: Unintended Consequences for Stem Cell Development.

Stem Cells Transl Med 2015 Oct 18;4(10):1097-100. Epub 2015 Aug 18.

Carpenter Group Consulting, Inc., Seattle, Washington, USA.

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http://dx.doi.org/10.5966/sctm.2015-0045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572901PMC
October 2015

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.

Circ Res 2015 Sep 19;117(8):720-30. Epub 2015 Aug 19.

From the Division of Cardiology, Department of Medicine, Stanford Cardiovascular Institute (J.R., A.E., E.T., U.R., O.J.A., O.S., N.G.K., E.N., M.W., P.S.T., J.D.G., J.C.W.) and Department of Pathology (A.J.C.), Stanford University School of Medicine, CA; Department for Research and Development, Veterans Administration Palo Alto Health Care System, CA (P.S.T.); Institute of Pharmacology, Heart Research Center, University Medical Center, Georg-August-University and German Center for Cardiovascular Research, Göttingen, Germany (M.T., T.M., W.H.Z.); and Center for Biomedicine and Genetics (V.C.C., L.A.C.) and Center for Applied Technology Development, Beckman Research Institute (A.J.C.), City of Hope, Duarte, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679370PMC
September 2015

Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells.

Stem Cell Res 2015 Sep 13;15(2):365-75. Epub 2015 Aug 13.

Center for Biomedicine and Genetics, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, CA 91010, USA; Center for Applied Technology Development, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.scr.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600677PMC
September 2015

Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation.

Cytotherapy 2013 Aug 7;15(8):999-1010. Epub 2013 May 7.

Buck Institute for Age Research, Novato, California 94945, USA.

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http://dx.doi.org/10.1016/j.jcyt.2013.03.006DOI Listing
August 2013

Epigenetic stability, adaptability, and reversibility in human embryonic stem cells.

Proc Natl Acad Sci U S A 2012 Jul 16;109(31):12544-9. Epub 2012 Jul 16.

Department of Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1209620109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411986PMC
July 2012

Scalable GMP compliant suspension culture system for human ES cells.

Stem Cell Res 2012 May 22;8(3):388-402. Epub 2012 Feb 22.

Center for Biomedicine and Genetics, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.scr.2012.02.001DOI Listing
May 2012

GMP scale-up and banking of pluripotent stem cells for cellular therapy applications.

Methods Mol Biol 2011 ;767:147-59

Center for Biomedicine and Genetics, Center for Applied Technology Development, Beckman Research Institute of City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1007/978-1-61779-201-4_11DOI Listing
November 2011

Replication-competent lentivirus analysis of clinical grade vector products.

Mol Ther 2011 Mar 21;19(3):557-66. Epub 2010 Dec 21.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1038/mt.2010.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048188PMC
March 2011

Regulatory considerations for the development of autologous induced pluripotent stem cell therapies.

Regen Med 2010 Jul;5(4):569-79

Center for Applied Technology Development, Beckman Research Institute of City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.2217/rme.10.55DOI Listing
July 2010

Scalable pluripotent stem cell culture.

Authors:
Larry A Couture

Nat Biotechnol 2010 Jun;28(6):562-3

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http://www.nature.com/articles/nbt0610-562
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http://dx.doi.org/10.1038/nbt0610-562DOI Listing
June 2010

Safety and immunological efficacy of a prostate cancer plasmid DNA vaccine encoding prostatic acid phosphatase (PAP).

Vaccine 2006 Jan 9;24(3):293-303. Epub 2005 Aug 9.

Department of Medicine, Section of Medical Oncology, University of Wisconsin-Madison, K4/518 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA.

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http://dx.doi.org/10.1016/j.vaccine.2005.07.074DOI Listing
January 2006