Lara Lipton

Lara Lipton

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Lara Lipton

Lara Lipton

Publications by authors named "Lara Lipton"

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Precision oncology using a clinician-directed, tailored approach to molecular profiling.

Asia Pac J Clin Oncol 2018 Feb 30;14(1):84-90. Epub 2017 Oct 30.

Department of Medical Oncology, The Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/ajco.12787DOI Listing
February 2018

Regorafenib for the Treatment of Advanced Gastric Cancer (INTEGRATE): A Multinational Placebo-Controlled Phase II Trial.

J Clin Oncol 2016 08 20;34(23):2728-35. Epub 2016 Jun 20.

Nick Pavlakis, Niall C. Tebbutt, Lara R. Lipton, John R. Zalcberg, John Simes, and David Goldstein, Australasian Gastro-Intestinal Trials Group; Nick Pavlakis, Royal North Shore Hospital, University of Sydney; Katrin M. Sjoquist, Andrew J. Martin, Eric Tsobanis, Sonia Yip, and John Simes, National Health and Medical Research Council Clinical Trials Centre, University of Sydney; Katrin M. Sjoquist, Cancer Care Centre, St George Hospital; Sonia Yip, Sydney Catalyst Translational Cancer Research Centre; Mark Wong, Westmead Hospital; David Goldstein, Prince of Wales Hospital, Sydney, New South Wales; Niall C. Tebbutt, Austin Health; Lara R. Lipton, Western Health; Andrew Strickland, Monash Medical Centre; John R. Zalcberg, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Yoon-Koo Kang, Asan Medical Center, University of Ulsan College of Medicine; Yung-Jue Bang, Seoul National University Hospital; Sun Young Rha, Yonsei University College of Medicine; Jeeyun Lee, Samsung Medical Center, Sungkyunkwan University School of Medicine; Jae-Yong Cho, Gangnam Severance Cancer Hospital, Yonsei University College of Medicine, Seoul; Jin Won Kim, Seoul National University Bundang Hospital, Seongnam, South Korea; Thierry Alcindor, McGill University Health Centre, Montreal, Quebec; Christopher J. O'Callaghan, National Cancer Institute of Canada Clinical Trials Group, Kingston, Ontario; and Margot J. Burnell, Saint John Regional Hospital, Saint John, New Brunswick, Canada.

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http://dx.doi.org/10.1200/JCO.2015.65.1901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019744PMC
August 2016

Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine.

Drug Discov Today 2015 Dec 19;20(12):1429-32. Epub 2015 Oct 19.

School of Public Health & Preventive Medicine, Department of Epidemiology & Preventive Medicine, Monash Faculty of Medicine Nursing & Health Sciences, Alfred Hospital, Prahran,, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/j.drudis.2015.10.009DOI Listing
December 2015

Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.

Clin Cancer Res 2013 Dec 1;19(23):6430-7. Epub 2013 Oct 1.

Authors' Affiliations: Department of Surgery, Division of Surgical Oncology, Center for Genomic Medicine, Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts; Genome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, California; Department of Epidemiology and Statistics, Memorial Sloan-Kettering Cancer Center, New York; RIKEN Center for Genomic Medicine, Tokyo, Japan; Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Edinburgh; Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; Ludwig Colon Cancer Initiative Laboratory, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville; Genetic and Molecular Epidemiology Laboratories, and Familial Cancer laboratory, Queensland Institute of Medical Research, Brisbane; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia; and Department of Medicine, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037290PMC
December 2013

Germline SDHC mutation presenting as recurrent SDH deficient GIST and renal carcinoma.

Pathology 2013 12;45(7):689-91

*Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards †Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards ‡Sydney Medical School, University of Sydney, Sydney §Cancer Genetics, Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW ||Genetic Medicine and Familial Cancer Centre, Royal Melbourne Hospital, Parkville ¶Department of Surgery, Monash Medical School, Melbourne **Department of Medical Oncology, Cabrini Hospital, Melbourne ††Department of Medicine, Monash Medical School, Monash University, Melbourne ‡‡Department of Anatomical Pathology, Royal Children's Hospital, Parkville, Vic Australia.

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http://dx.doi.org/10.1097/PAT.0000000000000018DOI Listing
December 2013

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.

Am J Gastroenterol 2013 Nov 17;108(11):1785-93. Epub 2013 Sep 17.

1] Ludwig Colon Cancer Initiative Laboratory, Ludwig Institute for Cancer Research, Parkville, Victoria, Australia [2] Faculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/ajg.2013.292DOI Listing
November 2013

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.

Clin Cancer Res 2009 Dec;15(24):7642-7651

Authors' Affiliations: Ludwig Colon Cancer Initiative Laboratory, Ludwig Institute for Cancer Research; Anatomic Pathology Department, Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom; Department of Medical Genetics, Biomedicum, University of Helsinki, Helsinki, Finland; Group of Molecular Oncology, Nanomedicine Research Program, Molecular Biology and Biochemistry Research Center (Centro de Investigación Bioquímica y Biología Molecular), Vall d'Hebron Hospital Research Institute, Barcelona, Spain; Molecular Diagnostic Laboratory, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark; and GI Surgical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920750PMC
December 2009

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

Nat Genet 2008 May 30;40(5):623-30. Epub 2008 Mar 30.

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/ng.111DOI Listing
May 2008

Cytosine methylation profiling of cancer cell lines.

Proc Natl Acad Sci U S A 2008 Mar 19;105(12):4844-9. Epub 2008 Mar 19.

Sequenom, Inc., 3595 John Hopkins Court, San Diego, CA 92109, USA.

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http://dx.doi.org/10.1073/pnas.0712251105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290817PMC
March 2008

Biallelic PMS2 mutations and a distinctive childhood cancer syndrome.

J Pediatr Hematol Oncol 2008 Mar;30(3):254-7

Genetic Health Services Victoria, Murdoch Children's Research Institute, Parkville VIC 3052,F

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http://dx.doi.org/10.1097/MPH.0b013e318161aa20DOI Listing
March 2008

A family with juvenile polyposis linked to the BMPR1A locus: cryptic mutation or closely linked gene?

J Gastroenterol Hepatol 2007 Dec 15;22(12):2292-7. Epub 2007 Jun 15.

Department of Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1440-1746.2007.04989.xDOI Listing
December 2007

Adjuvant therapies for colorectal cancer.

World J Gastroenterol 2007 Jul;13(28):3799-805

Department of Medical Oncology and Clinical Haematology, Western Hospital, Footscray 3011, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611211PMC
http://dx.doi.org/10.3748/wjg.v13.i28.3799DOI Listing
July 2007

Metastatic colorectal cancer-past, progress and future.

World J Gastroenterol 2007 Jul;13(28):3806-15

Department of Medical Oncology and Clinical Haematology, Western Hospital, Footscray 3011, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611212PMC
http://dx.doi.org/10.3748/wjg.v13.i28.3806DOI Listing
July 2007

The genetics of FAP and FAP-like syndromes.

Fam Cancer 2006 ;5(3):221-6

Molecular and Population Genetics Laboratory, Cancer Research UK, London, WC2A 3PX, UK.

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http://dx.doi.org/10.1007/s10689-005-5673-3DOI Listing
December 2006

Prospective results of surveillance colonoscopy in dominant familial colorectal cancer with and without Lynch syndrome.

Gastroenterology 2006 Jun;130(7):1995-2000

Family Cancer Group, Cancer Research, UK Colorectal Cancer Unit, St. Mark's Hospital, Watford Road, Harrow, Middlesex, United Kingdom.

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http://dx.doi.org/10.1053/j.gastro.2006.03.018DOI Listing
June 2006

A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family history.

Fam Cancer 2005 ;4(2):127-33

Department of Medicine, Division of Gastroenterology and the Comprehensive Cancer Center, University of California-San Francisco, 2330 Post Street, San Francisco, CA 94115-1623, USA.

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http://dx.doi.org/10.1007/s10689-004-5814-0DOI Listing
September 2005

Colorectal cancer and inherited mutations in base-excision repair.

Lancet Oncol 2004 Oct;5(10):600-6

Royal Melbourne Hospital, Victoria, Australia.

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http://dx.doi.org/10.1016/S1470-2045(04)01595-5DOI Listing
October 2004

The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.

Clin Gastroenterol Hepatol 2004 Aug;2(8):633-8

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom.

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August 2004

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.

Cancer Res 2003 Nov;63(22):7595-9

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research United Kingdom, London WC2A 3PX, United Kingdom.

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November 2003

Contribution of the CHEK2 1100delC variant to risk of multiple colorectal adenoma and carcinoma.

Cancer Lett 2003 Oct;200(2):149-52

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1016/s0304-3835(03)00391-4DOI Listing
October 2003

Colorectal tumourigenesis in carriers of the APC I1307K variant: lone gunman or conspiracy?

J Pathol 2003 Feb;199(2):137-9

Molecular and Population Genetics Laboratory, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://doi.wiley.com/10.1002/path.1272
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http://dx.doi.org/10.1002/path.1272DOI Listing
February 2003

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

N Engl J Med 2003 Feb;348(9):791-9

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa025283DOI Listing
February 2003