Publications by authors named "Lance E Lanyon"

39Publications

Sclerostin's role in bone's adaptive response to mechanical loading.

Bone 2017 03 12;96:38-44. Epub 2016 Oct 12.

School of Veterinary Sciences, University of Bristol, Langford House, Langford, Bristol BS40 5DU, United Kingdom.

View Article and Find Full Text PDF
March 2017

Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone.

PLoS One 2015 9;10(10):e0140260. Epub 2015 Oct 9.

School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.

View Article and Find Full Text PDF
June 2016

Exercise does not enhance aged bone's impaired response to artificial loading in C57Bl/6 mice.

Bone 2015 Dec 2;81:47-52. Epub 2015 Jul 2.

School of Veterinary Sciences, University of Bristol, Bristol BS40 5DU, UK.

View Article and Find Full Text PDF
December 2015

The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in Bone.

Front Endocrinol (Lausanne) 2014 1;5:154. Epub 2014 Oct 1.

School of Veterinary Sciences, University of Bristol , Bristol , UK.

View Article and Find Full Text PDF
October 2014

Protein kinase Cα (PKCα) regulates bone architecture and osteoblast activity.

J Biol Chem 2014 Sep 28;289(37):25509-22. Epub 2014 Jul 28.

From the School of Veterinary Sciences, University of Bristol, Bristol BS2 8EJ, United Kingdom and.

View Article and Find Full Text PDF
September 2014

Estrogen receptors' roles in the control of mechanically adaptive bone (re)modeling.

Bonekey Rep 2013 Sep 4;2:413. Epub 2013 Sep 4.

School of Veterinary Sciences, University of Bristol , Bristol, UK.

View Article and Find Full Text PDF
September 2013

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4.

FEBS Lett 2011 Aug 28;585(15):2450-4. Epub 2011 Jun 28.

School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.

View Article and Find Full Text PDF
August 2011

Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading.

Curr Osteoporos Rep 2011 Jun;9(2):76-82

School of Veterinary Sciences, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK.

View Article and Find Full Text PDF
June 2011

Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice.

Endocrinology 2010 Dec 13;151(12):5582-90. Epub 2010 Oct 13.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, London NW1 0TU, UK.

View Article and Find Full Text PDF
December 2010

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse.

Bone 2010 Mar 24;46(3):628-42. Epub 2009 Oct 24.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.

View Article and Find Full Text PDF
March 2010

Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones.

Bone 2010 Feb 3;46(2):314-21. Epub 2009 Sep 3.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.

View Article and Find Full Text PDF
February 2010

The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.

Bone 2009 May 14;44(5):930-5. Epub 2009 Jan 14.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, London, UK.

View Article and Find Full Text PDF
May 2009

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice.

Bone 2008 Aug 1;43(2):238-48. Epub 2008 May 1.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.

View Article and Find Full Text PDF
August 2008

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha.

J Biol Chem 2007 Jul 8;282(28):20715-27. Epub 2007 May 8.

Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London, United Kingdom.

View Article and Find Full Text PDF
July 2007

Sympathetic nervous system does not mediate the load-induced cortical new bone formation.

J Bone Miner Res 2005 Dec 8;20(12):2159-68. Epub 2005 Aug 8.

Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom.

View Article and Find Full Text PDF
December 2005

Mechanical loading influences bone mass through estrogen receptor alpha.

Exerc Sport Sci Rev 2004 Apr;32(2):64-8

The Royal Veterinary College, Royal College Street, London, United Kingdom.

View Article and Find Full Text PDF
April 2004

Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone.

Am J Physiol Cell Physiol 2003 Apr 11;284(4):C934-43. Epub 2002 Dec 11.

Department of Veterinary Basic Science, Royal Veterinary College, London NW1 0TU, United Kingdom.

View Article and Find Full Text PDF
April 2003

Mechanical strain and bone cell function: a review.

Osteoporos Int 2002 Sep;13(9):688-700

Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London NW1 0TU, UK.

View Article and Find Full Text PDF
September 2002