Publications by authors named "Lan Tan"

100Publications

Association of Serum Complement C1q Concentration with Severity of Neurological Impairment and Infarct size in Patients with Acute Ischemic Stroke.

J Stroke Cerebrovasc Dis 2020 Oct 14;29(12):105363. Epub 2020 Oct 14.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, China. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105363DOI Listing
October 2020

Plasma amyloid, tau, and neurodegeneration biomarker profiles predict Alzheimer's disease pathology and clinical progression in older adults without dementia.

Alzheimers Dement (Amst) 2020 24;12(1):e12104. Epub 2020 Sep 24.

Department of Neurology and Institute of Neurology Huashan Hospital Shanghai Medical College Fudan University Shanghai China.

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http://dx.doi.org/10.1002/dad2.12104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513626PMC
September 2020

A panel of blood lipids associated with cognitive performance, brain atrophy, and Alzheimer's diagnosis: A longitudinal study of elders without dementia.

Alzheimers Dement (Amst) 2020 15;12(1):e12041. Epub 2020 Sep 15.

Department of Neurology and Institute of Neurology Huashan Hospital Shanghai Medical College Fudan University Shanghai China.

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http://dx.doi.org/10.1002/dad2.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507431PMC
September 2020

Association of Occupational Factors and Dementia or Cognitive Impairment: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2020 Sep 19. Epub 2020 Sep 19.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-200605DOI Listing
September 2020

Elevated Tau PET Signal Depends on Abnormal Amyloid Levels and Correlates with Cognitive Impairment in Elderly Persons without Dementia.

J Alzheimers Dis 2020 Sep 23. Epub 2020 Sep 23.

Department of Neurology and Institute of Neurology, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-200526DOI Listing
September 2020

Amyloid Pathologies Modulate the Associations of Minimal Depressive Symptoms With Cognitive Impairments in Older Adults Without Dementia.

Biol Psychiatry 2020 Jul 15. Epub 2020 Jul 15.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2020.07.004DOI Listing
July 2020

High pulse pressure is a risk factor for prodromal Alzheimer's disease: a longitudinal study.

Aging (Albany NY) 2020 Sep 22;12(18):18221-18237. Epub 2020 Sep 22.

Department of Neurology, The Affiliated Hospital of Qingdao University, Qingdao, China.

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http://dx.doi.org/10.18632/aging.103678DOI Listing
September 2020

Associations of sleep characteristics with alpha-synuclein in cerebrospinal fluid in older adults.

Ann Clin Transl Neurol 2020 Oct 19;7(10):2026-2034. Epub 2020 Sep 19.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/acn3.51204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545588PMC
October 2020

Discordant Alzheimer's neurodegenerative biomarkers and their clinical outcomes.

Ann Clin Transl Neurol 2020 Oct 19;7(10):1996-2009. Epub 2020 Sep 19.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/acn3.51196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545611PMC
October 2020

Association of serum Apolipoprotein B with cerebrospinal fluid biomarkers of Alzheimer's pathology.

Ann Clin Transl Neurol 2020 Oct 10;7(10):1766-1778. Epub 2020 Sep 10.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/acn3.51153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545610PMC
October 2020

Associations of Green Tea Consumption and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Pathology in Cognitively Intact Older Adults: The CABLE Study.

J Alzheimers Dis 2020 ;77(1):411-421

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-200410DOI Listing
January 2020

Clinical and biomarker trajectories in sporadic Alzheimer's disease: A longitudinal study.

Alzheimers Dement (Amst) 2020 12;12(1):e12095. Epub 2020 Aug 12.

Department of Neurology and Institute of Neurology Huashan Hospital Shanghai Medical College Fudan University Shanghai China.

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http://dx.doi.org/10.1002/dad2.12095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421532PMC
August 2020

Plasma sex hormone-binding globulin predicts neurodegeneration and clinical progression in prodromal Alzheimer's disease.

Aging (Albany NY) 2020 07 22;12(14):14528-14541. Epub 2020 Jul 22.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.103497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425468PMC
July 2020

Weight Loss is a Preclinical Signal of Cerebral Amyloid Deposition and Could Predict Cognitive Impairment in Elderly Adults.

J Alzheimers Dis 2020 ;77(1):449-456

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3233/JAD-200524DOI Listing
January 2020

Sleep characteristics and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact older adults: The CABLE study.

Alzheimers Dement 2020 08 13;16(8):1146-1152. Epub 2020 Jul 13.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/alz.12117DOI Listing
August 2020

Pharmacological treatment of neuropsychiatric symptoms of dementia: a network meta-analysis protocol.

Ann Transl Med 2020 Jun;8(12):746

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.21037/atm-20-611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333122PMC
June 2020

Selective neuronal vulnerability in Alzheimer's disease.

Ageing Res Rev 2020 09 20;62:101114. Epub 2020 Jun 20.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2020.101114DOI Listing
September 2020

Association of body mass index with risk of cognitive impairment and dementia: A systematic review and meta-analysis of prospective studies.

Neurosci Biobehav Rev 2020 08 30;115:189-198. Epub 2020 May 30.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2020.05.012DOI Listing
August 2020

Associations of Subsyndromal Symptomatic Depression with Cognitive Decline and Brain Atrophy in Elderly Individuals without Dementia: A Longitudinal Study.

J Affect Disord 2020 Sep 23;274:262-268. Epub 2020 May 23.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.05.097DOI Listing
September 2020

Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies.

Hypertension 2020 Jul 26;76(1):217-225. Epub 2020 May 26.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, China (X.-N.S., Q.D., J.-T.Y.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14993DOI Listing
July 2020

Association of cerebrospinal fluid neurogranin levels with cognition and neurodegeneration in Alzheimer's disease.

Aging (Albany NY) 2020 05 18;12(10):9365-9379. Epub 2020 May 18.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.103211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288926PMC
May 2020

Longitudinal trajectories of Alzheimer's ATN biomarkers in elderly persons without dementia.

Alzheimers Res Ther 2020 05 11;12(1):55. Epub 2020 May 11.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1186/s13195-020-00621-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216714PMC
May 2020

Cognitive Effects of Treating Obstructive Sleep Apnea: A Meta-Analysis of Randomized Controlled Trials.

J Alzheimers Dis 2020 ;75(3):705-715

Department of Neurology, the Affiliated Hospital of Qingdao University, China.

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http://dx.doi.org/10.3233/JAD-200088DOI Listing
January 2020

Prevalence of the Preclinical Stages of Alzheimer's Disease in Cognitively Intact Older Adults: The CABLE Study.

J Alzheimers Dis 2020 ;75(2):483-492

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-200059DOI Listing
January 2020

Plasma Neurofilament Light and Longitudinal Progression of White Matter Hyperintensity in Elderly Persons Without Dementia.

J Alzheimers Dis 2020 ;75(3):729-737

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-200022DOI Listing
January 2020

Association of Cerebral Microbleeds with Cognitive Decline: A Longitudinal Study.

J Alzheimers Dis 2020 ;75(2):571-579

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191257DOI Listing
January 2020

Associations of Infectious Agents with Alzheimer's Disease: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2020 ;75(1):299-309

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191337DOI Listing
January 2020

Dynamic changes of CSF sTREM2 in preclinical Alzheimer's disease: the CABLE study.

Mol Neurodegener 2020 04 10;15(1):25. Epub 2020 Apr 10.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1186/s13024-020-00374-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149923PMC
April 2020

Fasting blood glucose and cerebrospinal fluid Alzheimer's biomarkers in non-diabetic cognitively normal elders: the CABLE study.

Aging (Albany NY) 2020 03 17;12(6):4945-4952. Epub 2020 Mar 17.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138563PMC
March 2020

Regional Amyloid Accumulation and White Matter Integrity in Cognitively Normal Individuals.

J Alzheimers Dis 2020 ;74(4):1261-1270

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191350DOI Listing
January 2020

Predictors of cognitive impairment in Parkinson's disease: a systematic review and meta-analysis of prospective cohort studies.

J Neurol 2020 Mar 12. Epub 2020 Mar 12.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s00415-020-09757-9DOI Listing
March 2020

Association of peripheral neutrophil count with intracranial atherosclerotic stenosis.

BMC Neurol 2020 Feb 22;20(1):65. Epub 2020 Feb 22.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1186/s12883-020-01641-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035752PMC
February 2020

Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia.

Neuroimage Clin 2020 6;26:102209. Epub 2020 Feb 6.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai 200040, China. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2020.102209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021640PMC
February 2020

Fasting glucose and HbA levels as risk factors for the presence of intracranial atherosclerotic stenosis.

Ann Transl Med 2019 Dec;7(24):804

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.

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http://dx.doi.org/10.21037/atm.2019.12.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989875PMC
December 2019

Serum Uric Acid Levels and Risk of Intracranial Atherosclerotic Stenosis: A Cross-Sectional Study.

Neurotox Res 2020 Apr 8;37(4):936-943. Epub 2020 Feb 8.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s12640-020-00171-7DOI Listing
April 2020

Late-life obesity is a protective factor for prodromal Alzheimer's disease: a longitudinal study.

Aging (Albany NY) 2020 01 25;12(2):2005-2017. Epub 2020 Jan 25.

Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing of ADNI investigators can be found at: http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdf.

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http://dx.doi.org/10.18632/aging.102738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053604PMC
January 2020

Genome-Wide Association Study Identifies SLAMF1 Affecting the Rate of Memory Decline.

J Alzheimers Dis 2020 ;74(1):139-149

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191214DOI Listing
January 2020

Association of antinuclear antibodies with the risk of intracranial arterial stenosis.

Aging (Albany NY) 2020 01 21;12(2):1322-1331. Epub 2020 Jan 21.

Department of Neurology, Qingdao Municipal Hospital, Qingdao Clinical Medical College, Nanjing Medical University, Qingdao, China.

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http://dx.doi.org/10.18632/aging.102685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053607PMC
January 2020

Genome-wide association study of cerebrospinal fluid neurofilament light levels in non-demented elders.

Ann Transl Med 2019 Nov;7(22):657

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2019.10.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944624PMC
November 2019

Modifiable risk factors for carotid atherosclerosis: a meta-analysis and systematic review.

Ann Transl Med 2019 Nov;7(22):632

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.

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http://dx.doi.org/10.21037/atm.2019.10.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944535PMC
November 2019

Midlife Modifiable Risk Factors for Dementia: A Systematic Review and Meta-analysis of 34 Prospective Cohort Studies.

Curr Alzheimer Res 2019 ;16(14):1254-1268

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.2174/1567205017666200103111253DOI Listing
October 2020

The Prevalence of Dementia: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2020 ;73(3):1157-1166

Department of Neurology & Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191092DOI Listing
January 2020

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis.

J Neurol Neurosurg Psychiatry 2020 03 26;91(3):236-244. Epub 2019 Dec 26.

Neurology Department, Qingdao Municipal Hospital Group, Qingdao University, Qingdao, Shandong, China.

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http://dx.doi.org/10.1136/jnnp-2019-321896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035682PMC
March 2020

Associations of White Matter Hyperintensities with Cognitive Decline: A Longitudinal Study.

J Alzheimers Dis 2020 ;73(2):759-768

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-191005DOI Listing
January 2020

Metabolically healthy obesity reduces the risk of Alzheimer's disease in elders: a longitudinal study.

Aging (Albany NY) 2019 12 2;11(23):10939-10951. Epub 2019 Dec 2.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932886PMC
December 2019

Genome-wide association study of hippocampal atrophy rate in non-demented elders.

Aging (Albany NY) 2019 11 23;11(22):10468-10484. Epub 2019 Nov 23.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914394PMC
November 2019

Neurofilament Light Chain in Cerebrospinal Fluid and Blood as a Biomarker for Neurodegenerative Diseases: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2019 ;72(4):1353-1361

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3233/JAD-190615DOI Listing
January 2019

Common Variant in TREM1 Influencing Brain Amyloid Deposition in Mild Cognitive Impairment and Alzheimer's Disease.

Neurotox Res 2020 Mar 13;37(3):661-668. Epub 2019 Nov 13.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12 Wulumuqi Road, Shanghai, China.

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http://dx.doi.org/10.1007/s12640-019-00105-yDOI Listing
March 2020

Genome-wide association study identifies locus influencing the rate of ventricular enlargement in non-demented elders.

Aging (Albany NY) 2019 11 11;11(21):9862-9874. Epub 2019 Nov 11.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874439PMC
November 2019

Blood pressure lowering and stroke prevention: a systematic review and network meta-analysis protocol.

Ann Transl Med 2019 Sep;7(18):489

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.

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http://dx.doi.org/10.21037/atm.2019.08.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803191PMC
September 2019

Elevated Hs-CRP Levels Are Associated with Higher Risk of Intracranial Arterial Stenosis.

Neurotox Res 2020 Feb 5;37(2):425-432. Epub 2019 Nov 5.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s12640-019-00108-9DOI Listing
February 2020

Neurofilament light chain plasma concentration predicts neurodegeneration and clinical progression in nondemented elderly adults.

Aging (Albany NY) 2019 09 12;11(17):6904-6914. Epub 2019 Sep 12.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756875PMC
September 2019

Apolipoprotein B/AI ratio as an independent risk factor for intracranial atherosclerotic stenosis.

Aging (Albany NY) 2019 09 3;11(17):6851-6862. Epub 2019 Sep 3.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756877PMC
September 2019

Diabetes mellitus and risks of cognitive impairment and dementia: A systematic review and meta-analysis of 144 prospective studies.

Ageing Res Rev 2019 11 17;55:100944. Epub 2019 Aug 17.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.100944DOI Listing
November 2019

Frequency and longitudinal clinical outcomes of Alzheimer's AT(N) biomarker profiles: A longitudinal study.

Alzheimers Dement 2019 09 6;15(9):1208-1217. Epub 2019 Aug 6.

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA; Department of Radiology, University of California, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, CA, USA; Department of Neurology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.05.006DOI Listing
September 2019

A Candidate Regulatory Variant at the Gene Cluster Confer Alzheimer's Disease Risk by Modulating Both Amyloid-β Pathology and Neuronal Degeneration.

Front Neurosci 2019 17;13:742. Epub 2019 Jul 17.

Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.3389/fnins.2019.00742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650562PMC
July 2019

Genome-wide association study identifies affecting the rate of CSF Aβ decline in non-demented elders.

Aging (Albany NY) 2019 08 1;11(15):5433-5444. Epub 2019 Aug 1.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710044PMC
August 2019

Genome-wide association study identifies CD1A associated with rate of increase in plasma neurofilament light in non-demented elders.

Aging (Albany NY) 2019 07;11(13):4521-4535

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.102066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660034PMC
July 2019

FDG-PET as an independent biomarker for Alzheimer's biological diagnosis: a longitudinal study.

Alzheimers Res Ther 2019 06 29;11(1):57. Epub 2019 Jun 29.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, 12th Wulumuqi Zhong Road, Shanghai, 200040, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599313PMC
June 2019

Intraoperative Computed Tomography Scan for Orbital Fracture Reconstruction.

J Craniofac Surg 2019 Oct;30(7):2159-2162

Centre for Oral & Maxillofacial Surgery, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1097/SCS.0000000000005667DOI Listing
October 2019

Genome-Wide Association Study of Cerebral Microbleeds on MRI.

Neurotox Res 2020 Jan 18;37(1):146-155. Epub 2019 Jun 18.

Department of Neurology and Institute of Neurology, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, No. 12 Wulumuqi Road, Shanghai, China.

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http://dx.doi.org/10.1007/s12640-019-00073-3DOI Listing
January 2020

Genome-wide association study identifies Alzheimer's risk variant in MS4A6A influencing cerebrospinal fluid sTREM2 levels.

Neurobiol Aging 2019 12 21;84:241.e13-241.e20. Epub 2019 May 21.

Department of Neurology and Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.05.008DOI Listing
December 2019

Elevated homocysteine as an independent risk for intracranial atherosclerotic stenosis.

Aging (Albany NY) 2019 06;11(11):3824-3831

Department of Neurology, The Affiliated Hospital of Qingdao University, Qingdao, China.

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http://dx.doi.org/10.18632/aging.102019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594800PMC
June 2019

Mutation Mediate Alzheimer's Disease Risk by Altering Neuronal Degeneration.

Front Neurosci 2019 15;13:455. Epub 2019 May 15.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3389/fnins.2019.00455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529571PMC
May 2019

Common Variants in ABI3 Influence Cerebrospinal Fluid Total Tau Levels and Cognitive Decline in Progressive Mild Cognitive Impairment Patients.

J Alzheimers Dis 2019 ;70(1):17-23

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, China.

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http://dx.doi.org/10.3233/JAD-190153DOI Listing
September 2020

Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study.

Aging (Albany NY) 2019 05;11(10):3156-3169

Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing of ADNI investigators can be found at: http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdf.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555452PMC
May 2019

Effects of CD33 Variants on Neuroimaging Biomarkers in Non-Demented Elders.

J Alzheimers Dis 2019 ;68(2):757-766

Department of Neurology, Qingdao Municipal Hospital, Dalian Medical University, China.

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http://dx.doi.org/10.3233/JAD-181062DOI Listing
July 2020

TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2019 ;68(3):1171-1184

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3233/JAD-181038DOI Listing
August 2020

Modifiable risk factors for cognitive impairment in Parkinson's disease: A systematic review and meta-analysis of prospective cohort studies.

Mov Disord 2019 06 14;34(6):876-883. Epub 2019 Mar 14.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/mds.27665DOI Listing
June 2019

The Influence of BDNF Val66Met Polymorphism on Cognition, Cerebrospinal Fluid, and Neuroimaging Markers in Non-Demented Elderly.

J Alzheimers Dis 2019 ;68(1):405-414

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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June 2020

rs242557 variant is associated with hippocampus tau uptake on F-AV-1451 PET in non-demented elders.

Aging (Albany NY) 2019 01;11(3):874-884

Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China; Institute of Neurology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/aging.101783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382414PMC
January 2019

Risk factors for intracranial atherosclerosis: A systematic review and meta-analysis.

Atherosclerosis 2019 02 23;281:71-77. Epub 2018 Dec 23.

Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China; Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.015DOI Listing
February 2019

Portable fibrobronchoscopic treatment for non-severe ischemic stroke-associated pneumonia patients with dysphagia: a pilot study.

Neurol Res 2019 Mar 18;41(3):216-222. Epub 2019 Jan 18.

e Department of Neurology, Huai'an First People's Hospital , The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University , Huai'an , Jiangsu , China.

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http://dx.doi.org/10.1080/01616412.2018.1548723DOI Listing
March 2019

Soluble TREM1 concentrations are increased and positively correlated with total tau levels in the plasma of patients with Alzheimer's disease.

Aging Clin Exp Res 2019 Dec 14;31(12):1801-1805. Epub 2019 Jan 14.

Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.

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http://dx.doi.org/10.1007/s40520-019-01122-9DOI Listing
December 2019

Early-Life Risk Factors for Dementia and Cognitive Impairment in Later Life: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2019 ;67(1):221-229

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3233/JAD-180856DOI Listing
March 2020

Inflammatory markers in Alzheimer's disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies.

J Neurol Neurosurg Psychiatry 2019 05 10;90(5):590-598. Epub 2019 Jan 10.

Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China

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http://dx.doi.org/10.1136/jnnp-2018-319148DOI Listing
May 2019

Common Variants in and Correlation to CSF-related Phenotypes in Alzheimer's Disease.

Front Neurosci 2018 18;12:946. Epub 2018 Dec 18.

Department of Neurology, Qingdao Clinical Medical School, Qingdao Municipal Hospital, Nanjing Medical University, Qingdao, China.

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http://dx.doi.org/10.3389/fnins.2018.00946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305543PMC
December 2018

ABCA7 genotype altered Aβ levels in cerebrospinal fluid in Alzheimer's disease without dementia.

Ann Transl Med 2018 Nov;6(22):437

Department of Neurology, Weifang Medical University, Weifang 261042, China.

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http://dx.doi.org/10.21037/atm.2018.07.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281527PMC
November 2018

Genome-wide association study identifies locus influencing brain glucose metabolism.

Ann Transl Med 2018 Nov;6(22):436

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2018.07.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281526PMC
November 2018

Comparative safety and effectiveness of cholinesterase inhibitors and memantine for Alzheimer's disease: a network meta-analysis of 41 randomized controlled trials.

Alzheimers Res Ther 2018 12 27;10(1):126. Epub 2018 Dec 27.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, No. 5 Donghai Middle Road, Qingdao, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309083PMC
December 2018

Blood Pressure and the Risk of Dementia: A Dose-Response Meta-Analysis of Prospective Studies.

Curr Neurovasc Res 2018 ;15(4):345-358

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, Shadong, China.

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http://dx.doi.org/10.2174/1567202616666181128114523DOI Listing
July 2019

Systems biology and gene networks in Alzheimer's disease.

Neurosci Biobehav Rev 2019 01 20;96:31-44. Epub 2018 Nov 20.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, China; Department of Neurology, Huashan Hospital, Fudan University, China. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2018.11.007DOI Listing
January 2019

SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE mice.

FASEB J 2019 03 21;33(3):3437-3450. Epub 2018 Nov 21.

Institute for Viral Hepatitis, Department of Infectious Diseases, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1096/fj.201800975RRRDOI Listing
March 2019

Risk Factors of Rapid Cognitive Decline in Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2018 ;66(2):497-515

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3233/JAD-180476DOI Listing
October 2019

Common Variant in PLD3 Influencing Cerebrospinal Fluid Total Tau Levels and Hippocampal Volumes in Mild Cognitive Impairment Patients from the ADNI Cohort.

J Alzheimers Dis 2018 ;65(3):871-876

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, China.

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http://dx.doi.org/10.3233/JAD-180431DOI Listing
August 2019

A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid.

Neurotox Res 2019 Jan 29;35(1):41-48. Epub 2018 Jun 29.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.1007/s12640-018-9922-2DOI Listing
January 2019

Models for predicting risk of dementia: a systematic review.

J Neurol Neurosurg Psychiatry 2019 04 28;90(4):373-379. Epub 2018 Jun 28.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China

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http://dx.doi.org/10.1136/jnnp-2018-318212DOI Listing
April 2019

The role of in Alzheimer's disease.

Ann Transl Med 2018 May;6(10):178

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2018.04.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994511PMC
May 2018

Innate immune activation in Alzheimer's disease.

Ann Transl Med 2018 May;6(10):177

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2018.04.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994517PMC
May 2018

Microglial priming in Alzheimer's disease.

Ann Transl Med 2018 May;6(10):176

Department of Neurology, Qingdao Municipal Hospital, Dalian Medical University, Qingdao 266000, China.

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http://dx.doi.org/10.21037/atm.2018.04.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994530PMC
May 2018

The impact of genetic variations on cerebrospinal fluid markers in Alzheimer's disease.

Ann Transl Med 2018 May;6(10):171

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2018.04.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994512PMC
May 2018

Meta-analysis of the association between and Alzheimer's disease.

Ann Transl Med 2018 May;6(10):169

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.

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http://dx.doi.org/10.21037/atm.2018.04.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994519PMC
May 2018

Rare Variants in PLD3 Increase Risk for Alzheimer's Disease in Han Chinese.

J Alzheimers Dis 2018 ;64(1):55-59

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, China.

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http://dx.doi.org/10.3233/JAD-180205DOI Listing
June 2019

Meta-Analysis of the Association between Variants in ABCA7 and Alzheimer's Disease.

J Alzheimers Dis 2018 ;63(4):1261-1267

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.3233/JAD-180107DOI Listing
June 2019

Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity.

BMC Med Genet 2018 05 11;19(1):75. Epub 2018 May 11.

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, No.5 Donghai Middle Road, Qingdao, 266071, Shandong Province, China.

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https://bmcmedgenet.biomedcentral.com/articles/10.1186/s1288
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948839PMC
May 2018

Genome-wide association study identifies two loci influencing plasma neurofilament light levels.

BMC Med Genomics 2018 05 10;11(1):47. Epub 2018 May 10.

Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Road, Wenzhou, 325000, Zhejiang Province, China.

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http://dx.doi.org/10.1186/s12920-018-0364-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946407PMC
May 2018

Clearance of Amyloid Beta and Tau in Alzheimer's Disease: from Mechanisms to Therapy.

Neurotox Res 2018 Oct 7;34(3):733-748. Epub 2018 Apr 7.

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, No.5 Donghai Middle Road, Qingdao, 266071, Shandong, China.

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October 2018