Lan Kluwe

Lan Kluwe

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Lan Kluwe

Publications by authors named "Lan Kluwe"

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Cytocompatibility of Titanium, Zirconia and Modified PEEK after Surface Treatment Using UV Light or Non-Thermal Plasma.

Int J Mol Sci 2019 Nov 8;20(22). Epub 2019 Nov 8.

Department of Oral and Maxillofacial Surgery, University Hospital Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/ijms20225596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888564PMC
November 2019

Minimal Effect of Bevacizumab Treatment on Residual Vestibular Schwannomas after Partial Resection in Young Neurofibromatosis Type 2 Patients.

Cancers (Basel) 2019 Nov 25;11(12). Epub 2019 Nov 25.

Department of Neurosurgery, University Hospital Tübingen, BW 72076 Tübingen, Germany.

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http://dx.doi.org/10.3390/cancers11121862DOI Listing
November 2019

Paeoniflorin inhibits tributyltin chloride-induced apoptosis in hypothalamic neurons via inhibition of MKK4-JNK signaling pathway.

J Ethnopharmacol 2019 Jun 13;237:1-8. Epub 2019 Mar 13.

Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 20032, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.03.030DOI Listing
June 2019

Enriching Stem/Progenitor Cells from Dental Pulp Cells by Low-density Culturing.

In Vivo 2019 Jan-Feb;33(1):23-29

Department of Oral and Maxillofacial Surgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.21873/invivo.11434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364054PMC
April 2019

Separating Response of Tumor and non-Tumor Cells to Drug by Quantifying a Mutation.

Anticancer Res 2019 Apr;39(4):1777-1783

Division of Plastic, Reconstructive and Aesthetic Surgery, Center of Surgical Sciences, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.21873/anticanres.13284DOI Listing
April 2019

Piezosurgery for Sagittal Split Osteotomy: Procedure Duration and Postoperative Sensory Perturbation.

J Oral Maxillofac Surg 2017 Sep 15;75(9):1941-1947. Epub 2017 May 15.

Head of Department of Oral and Maxillofacial Surgery, Academic Teaching Hospital Feldkirch, Feldkirch, Austria.

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http://dx.doi.org/10.1016/j.joms.2017.05.003DOI Listing
September 2017

Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas.

Eur J Oral Sci 2017 04 2;125(2):95-101. Epub 2017 Feb 2.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1111/eos.12333
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http://dx.doi.org/10.1111/eos.12333DOI Listing
April 2017

Attachment, Viability and Adipodifferentiation of Pre-adipose Cells on Silk Scaffolds with and Without Co-expressed FGF-2 and VEGF.

In Vivo 2016 09-10;30(5):567-72

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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March 2017

Digital PCR for discriminating mosaic deletions and for determining proportion of tumor cells in specimen.

Authors:
Lan Kluwe

Eur J Hum Genet 2016 11 8;24(11):1644-1648. Epub 2016 Jun 8.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1038/ejhg.2016.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110055PMC
November 2016

Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients.

Cancer Immunol Immunother 2016 09 23;65(9):1113-21. Epub 2016 Jul 23.

Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00262-016-1871-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995232PMC
September 2016

The importance of nerve microenvironment for schwannoma development.

Acta Neuropathol 2016 08 28;132(2):289-307. Epub 2016 May 28.

Leibniz Institute on Aging, Fritz Lipmann Institute, Beutenbergstrasse 11, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s00401-016-1583-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947119PMC
August 2016

The feasibility of immediately loading dental implants in edentulous jaws.

J Periodontal Implant Sci 2016 Aug 30;46(4):234-43. Epub 2016 Aug 30.

Private Practice for Dentistry and Oral Surgery, Oppenheim, Germany .

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http://dx.doi.org/10.5051/jpis.2016.46.4.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005811PMC
August 2016

Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy.

Clin Oral Investig 2016 Jul 26;20(6):1279-82. Epub 2015 Oct 26.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, 52 Martinistrasse, Hamburg, 20246, Germany.

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http://dx.doi.org/10.1007/s00784-015-1627-9DOI Listing
July 2016

Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy.

Biomed Res Int 2015 6;2015:120903. Epub 2015 Aug 6.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1155/2015/120903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543372PMC
June 2016

A novel genetic- and cell-based tool for assessing the efficacy and toxicity of anticancer drugs in vitro.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2016 Mar 10;160(1):64-9. Epub 2015 Nov 10.

Laboratory for Tumor Biology and Regenerative Medicine, Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.5507/bp.2015.057DOI Listing
March 2016

Assessing Specificity of Anticancer Drugs In Vitro.

Authors:
Lan Kluwe

J Vis Exp 2016 Mar 23(109):e53752. Epub 2016 Mar 23.

Department of Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf; Department of Neurology, University Medical Center Hamburg-Eppendorf; Laboratory for Tumor Biology and Regenerative Medicine, University Medical Center Hamburg-Eppendorf;

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http://dx.doi.org/10.3791/53752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841310PMC
March 2016

Postoperative bleeding risk for oral surgery under continued clopidogrel antiplatelet therapy.

Biomed Res Int 2015 6;2015:823651. Epub 2015 Jan 6.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany ; Department of Oral and Maxillofacial Surgery, General Hospital Balingen, Tuebinger Straße 30, 72336 Balingen, Germany.

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http://dx.doi.org/10.1155/2015/823651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303007PMC
October 2015

Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China.

In Vivo 2015 Jan-Feb;29(1):109-15

Gynecology Department, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China

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September 2015

Optimized in vitro procedure for assessing the cytocompatibility of magnesium-based biomaterials.

Acta Biomater 2015 Sep 11;23:354-363. Epub 2015 Jun 11.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1016/j.actbio.2015.06.005DOI Listing
September 2015

Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1.

Am J Med Genet A 2015 Jul 21;167(7):1518-24. Epub 2015 Apr 21.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/ajmg.a.37068DOI Listing
July 2015

Nilotinib is more potent than imatinib for treating plexiform neurofibroma in vitro and in vivo.

PLoS One 2014 23;9(10):e107760. Epub 2014 Oct 23.

Berlin Brandenburg Center for Regenerative Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany; Seoul National University, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207688PMC
June 2015

Is immediate bony microsurgical reconstruction after head and neck tumor ablation associated with a higher rate of local recurrence?

J Craniomaxillofac Surg 2015 Apr 23;43(3):373-5. Epub 2015 Jan 23.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10105182150001
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http://dx.doi.org/10.1016/j.jcms.2015.01.006DOI Listing
April 2015

Preclinical assessment of the anticancer drug response of plexiform neurofibroma tissue using primary cultures.

J Clin Neurol 2015 Apr;11(2):172-7

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.3988/jcn.2015.11.2.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387483PMC
April 2015

Lack of evidence for increased postoperative bleeding risk for dental osteotomy with continued aspirin therapy.

Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jan 16;119(1):17-9. Epub 2014 Sep 16.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.oooo.2014.08.016DOI Listing
January 2015

Fractal dimension of time-resolved autofluorescence discriminates tumour from healthy tissues in the oral cavity.

J Craniomaxillofac Surg 2014 Sep 25;42(6):852-4. Epub 2013 Dec 25.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jcms.2013.12.004DOI Listing
September 2014

Postoperative bleeding risk for cutaneous surgery in the head and neck region with continued phenprocoumon therapy.

J Craniomaxillofac Surg 2014 Jul 13;42(5):608-11. Epub 2013 Sep 13.

Department of Oral and Maxillofacial Surgery (Head: Prof. Dr. Max Heiland), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg 20246, Germany.

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http://dx.doi.org/10.1016/j.jcms.2013.08.006DOI Listing
July 2014

B-scan ultrasonographic monitoring of orthotopic xenografted plexiform neurofibroma in mice.

In Vivo 2013 Nov-Dec;27(6):723-7

DMD, Building O-10, Department of Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

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http://iv.iiarjournals.org/content/27/6/723.full.pdf
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July 2014

Lack of evidence for increased risk of postoperative bleeding after cutaneous surgery in the head and neck in patients taking aspirin.

Br J Oral Maxillofac Surg 2014 Jul 2;52(6):527-9. Epub 2014 Apr 2.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bjoms.2014.02.020DOI Listing
July 2014

Differences of 25-hydroxyvitamin D3 concentrations in children and adults with neurofibromatosis type 1.

Clin Biochem 2014 May 6;47(7-8):560-3. Epub 2014 Mar 6.

Department of Neurology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.clinbiochem.2014.02.020DOI Listing
May 2014

Immunohistochemical and FISH analysis of EGFR and its prognostic value in patients with oral squamous cell carcinoma.

J Oral Pathol Med 2014 Mar 11;43(3):205-10. Epub 2013 Sep 11.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/jop.12111DOI Listing
March 2014

P53 immunohistochemical expression does not correlate with clinical features in 207 carcinomas of the oral cavity and in the head and neck region.

Clin Oral Investig 2014 Jan 13;18(1):211-7. Epub 2013 Feb 13.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistr 52, 20246, Hamburg, Germany,

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http://dx.doi.org/10.1007/s00784-013-0939-xDOI Listing
January 2014

Efficacy and selectivity of nilotinib on NF1-associated tumors in vitro.

J Neurooncol 2014 Jan 31;116(2):231-6. Epub 2013 Oct 31.

Laboratory for Tumor Genetics, Department of Neurology, University Medical Center Hamburg-Eppendorf, Building O48, 4th Floor, Martinistr. 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s11060-013-1295-zDOI Listing
January 2014

Prognostic relevance of circulating tumor cells in blood and disseminated tumor cells in bone marrow of patients with squamous cell carcinoma of the oral cavity.

Clin Cancer Res 2014 Jan 11;20(2):425-33. Epub 2013 Nov 11.

Authors' Affiliations: Departments of Oral and Maxillofacial Surgery, Medical Biometry and Epidemiology, and Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-1101DOI Listing
January 2014

Lack of evidence for predictive and prognostic value of cyclin D1 gene polymorphism CCND1 G870A for oral squamous cell carcinoma.

Anticancer Res 2014 Jan;34(1):235-8

DMD, Department of Oral Maxillofacial Surgery, Building O10, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.

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January 2014

Amplification of the PPFIA1 gene region on 11q13 in oral squamous cell carcinomas (OSCC).

J Craniomaxillofac Surg 2013 Dec 26;41(8):845-9. Epub 2013 Feb 26.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jcms.2013.01.040DOI Listing
December 2013

Immunohistochemical analysis of p16 expression, HPV infection and its prognostic utility in oral squamous cell carcinoma.

J Oral Pathol Med 2013 Oct 31;42(9):676-81. Epub 2013 May 31.

Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/jop.12086DOI Listing
October 2013

Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors.

BMC Med 2013 Apr 23;11:109. Epub 2013 Apr 23.

Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany.

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http://dx.doi.org/10.1186/1741-7015-11-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648455PMC
April 2013

Efficacy and side effects of chinese herbal medicine for menopausal symptoms: a critical review.

Evid Based Complement Alternat Med 2012 13;2012:568106. Epub 2013 Jan 13.

Gynecology Department, Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China ; HanseMerkur Traditional Chinese Medicine Centre, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1155/2012/568106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551256PMC
February 2013

Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1 microdeletions.

BMC Med Genet 2012 Oct 26;13:98. Epub 2012 Oct 26.

Institute of Human Genetics, University of Ulm, Albert-Einstein-Allee, Ulm, Germany.

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http://dx.doi.org/10.1186/1471-2350-13-98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500256PMC
October 2012

Dissecting the clinical phenotype associated with mosaic type-2 NF1 microdeletions.

Neurogenetics 2012 Aug 13;13(3):229-36. Epub 2012 May 13.

Institute of Human Genetics, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.

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http://dx.doi.org/10.1007/s10048-012-0332-yDOI Listing
August 2012

Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus.

Int J Nanomedicine 2012 16;7:827-34. Epub 2012 Feb 16.

Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/IJN.S27803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284225PMC
June 2012

Allelic drop-out, allele imbalance, or loss of heterozygosity?

Authors:
Lan Kluwe

Genes Chromosomes Cancer 2012 May 1;51(5):521-2; author reply 523. Epub 2012 Feb 1.

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http://dx.doi.org/10.1002/gcc.21930DOI Listing
May 2012

Internal tumor burden in neurofibromatosis Type I patients with large NF1 deletions.

Genes Chromosomes Cancer 2012 May 1;51(5):447-51. Epub 2012 Feb 1.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/gcc.21931DOI Listing
May 2012

Chinese herb mix Tiáo-Gēng-Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats.

BMC Complement Altern Med 2011 Dec 30;11:137. Epub 2011 Dec 30.

Gynecology Department, Shanghai Yueyang Integrated Traditioanl Chinese Medicine and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Gan He Road 110, Shanghai, China.

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http://dx.doi.org/10.1186/1472-6882-11-137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286390PMC
December 2011

Plexiform neurofibromas in children with neurofibromatosis type 1: frequency and associated clinical deficits.

J Pediatr 2011 Oct 31;159(4):652-5.e2. Epub 2011 May 31.

Phacomatosis Section, Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jpeds.2011.04.008DOI Listing
October 2011

Effects of splicing mutations on NF2-transcripts: transcript analysis and information theoretic predictions.

Genes Chromosomes Cancer 2011 Aug 11;50(8):571-84. Epub 2011 May 11.

Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892-5766, USA.

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http://dx.doi.org/10.1002/gcc.20876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142993PMC
August 2011

Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden.

Neurogenetics 2010 Oct 1;11(4):391-400. Epub 2010 Apr 1.

Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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http://link.springer.com/content/pdf/10.1007/s10048-010-0240
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http://link.springer.com/10.1007/s10048-010-0240-y
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http://dx.doi.org/10.1007/s10048-010-0240-yDOI Listing
October 2010

Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.

Clin Cancer Res 2010 Oct 25;16(20):5048-57. Epub 2010 Aug 25.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837895PMC
October 2010

Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model.

J Neurooncol 2010 May 17;98(1):11-9. Epub 2009 Nov 17.

Department of Maxillofacial Surgery, University Medical Centre Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

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http://link.springer.com/10.1007/s11060-009-0049-4
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http://dx.doi.org/10.1007/s11060-009-0049-4DOI Listing
May 2010

Large intragenic deletions of the NF2 gene: breakpoints and associated phenotypes.

Genes Chromosomes Cancer 2010 Feb;49(2):171-5

Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/gcc.20733DOI Listing
February 2010

The spectrum of somatic and germline NF1 mutations in NF1 patients with spinal neurofibromas.

Neurogenetics 2009 Jul 17;10(3):251-63. Epub 2009 Feb 17.

Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff Cf144XN, UK.

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http://dx.doi.org/10.1007/s10048-009-0178-0DOI Listing
July 2009

Ral overactivation in malignant peripheral nerve sheath tumors.

Mol Cell Biol 2009 Jul 4;29(14):3964-74. Epub 2009 May 4.

Department of Medicine, KUMC-Molecular Medicine Laboratory, University of Kansas School of Medicine, 1000 Hixon, Mail Stop 4037, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.

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http://dx.doi.org/10.1128/MCB.01153-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704746PMC
July 2009

Mechanisms of loss of heterozygosity in neurofibromatosis type 1-associated plexiform neurofibromas.

J Invest Dermatol 2009 Mar 18;129(3):615-21. Epub 2008 Sep 18.

Institute of Human Genetics, University of Ulm, Germany.

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http://dx.doi.org/10.1038/jid.2008.274DOI Listing
March 2009

Correlation of nonsense and frameshift mutations with severity of retinal abnormalities in neurofibromatosis 2.

Arch Ophthalmol 2008 Oct;126(10):1376-80

Departments of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany..

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http://dx.doi.org/10.1001/archopht.126.10.1376DOI Listing
October 2008

Germline and somatic NF1 gene mutations in plexiform neurofibromas.

Hum Mutat 2008 Aug;29(8):E103-11

Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff CF144XN, UK.

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http://dx.doi.org/10.1002/humu.20793DOI Listing
August 2008

Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1.

Neuro Oncol 2008 Aug 17;10(4):593-8. Epub 2008 Jun 17.

Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1215/15228517-2008-011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666233PMC
August 2008

Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.

Genes Chromosomes Cancer 2008 Mar;47(3):238-46

Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1002/gcc.20525DOI Listing
March 2008

Histopathology and clinical outcome of NF1-associated vs. sporadic malignant peripheral nerve sheath tumors.

J Neurooncol 2007 Apr 17;82(2):187-92. Epub 2006 Nov 17.

Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.

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http://link.springer.com/10.1007/s11060-006-9266-2
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http://dx.doi.org/10.1007/s11060-006-9266-2DOI Listing
April 2007

Unilateral vestibular schwannoma with other neurofibromatosis type 2-related tumors: clinical and molecular study of a unique phenotype.

J Neurosurg 2006 Feb;104(2):201-7

Neurosurgical Service, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.

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http://dx.doi.org/10.3171/jns.2006.104.2.201DOI Listing
February 2006

Malignant peripheral nerve sheath tumors (MPNST) in neurofibromatosis type 1 (NF1): diagnostic findings on magnetic resonance images and mutation analysis of the NF1 gene.

Anticancer Res 2005 May-Jun;25(3A):1699-702

Maxillofacial Surgery Clinic, Eppendorf University Hospital, University of Hamburg, Germany.

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September 2005

Extensively high load of internal tumors determined by whole body MRI scanning in a patient with neurofibromatosis type 1 and a non-LCR-mediated 2-Mb deletion in 17q11.2.

Hum Genet 2005 May 18;116(6):466-75. Epub 2005 Mar 18.

Department of Human Genetics, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.

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http://dx.doi.org/10.1007/s00439-005-1265-4DOI Listing
May 2005

Screening for large mutations of the NF2 gene.

Genes Chromosomes Cancer 2005 Apr;42(4):384-91

Laboratory for Tumor Biology and Malformation, Department of Maxillofacial Surgery, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://doi.wiley.com/10.1002/gcc.20138
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http://dx.doi.org/10.1002/gcc.20138DOI Listing
April 2005

Do hormonal contraceptives stimulate growth of neurofibromas? A survey on 59 NF1 patients.

BMC Cancer 2005 Feb 9;5:16. Epub 2005 Feb 9.

Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-5-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549555PMC
February 2005

Prevalence of neurofibromatosis 1 in German children at elementary school enrollment.

Arch Dermatol 2005 Jan;141(1):71-4

Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1001/archderm.141.1.71DOI Listing
January 2005

Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients.

Cancer Cell Int 2004 May 17;4(1). Epub 2004 May 17.

Laboratory of Brain Tumor Biology, Department of Neurosurgery, University Hospital Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1186/1475-2867-4-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC425591PMC
May 2004

Screening 500 unselected neurofibromatosis 1 patients for deletions of the NF1 gene.

Hum Mutat 2004 Feb;23(2):111-6

Laboratory for Tumor Biology and Development Disorders, Department of Maxillofacial Surgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/humu.10299DOI Listing
February 2004

Constitutional NF1 mutations in neurofibromatosis 1 patients with malignant peripheral nerve sheath tumors.

Hum Mutat 2003 Nov;22(5):420

Department of Maxillofacial Surgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1002/humu.9193
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http://dx.doi.org/10.1002/humu.9193DOI Listing
November 2003

Polyneuropathy in neurofibromatosis 2: clinical findings, molecular genetics and neuropathological alterations in sural nerve biopsy specimens.

Acta Neuropathol 2002 Aug 18;104(2):179-87. Epub 2002 Apr 18.

Department of Neuropathology, University Clinic Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1007/s00401-002-0535-7DOI Listing
August 2002