Lam C Tsoi, MS, PhD - University of Michigan - Assistant Professor

Lam C Tsoi

MS, PhD

University of Michigan

Assistant Professor

Ann Arbor | United States

Main Specialties: Dermatology, Statistics

Additional Specialties: Translational Bioinformatics, Genomics, Genetics

ORCID logohttps://orcid.org/0000-0003-1627-5722

Lam C Tsoi, MS, PhD - University of Michigan - Assistant Professor

Lam C Tsoi

MS, PhD

Introduction

Primary Affiliation: University of Michigan - Ann Arbor , United States

Specialties:

Additional Specialties:


View Lam C Tsoi’s Resume / CV

Publications

35Publications

918Reads

26Profile Views

445PubMed Central Citations

TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.

Am J Hum Genet 2019 Aug 20;105(2):258-266. Epub 2019 Jun 20.

Center for Computational and Quantitative Genetics, Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698804PMC
August 2019
7 Reads
10.931 Impact Factor

A Transethnic Mendelian Randomization Study Identifies Causality of Obesity on Risk of Psoriasis.

J Invest Dermatol 2019 Jun 5;139(6):1397-1400. Epub 2018 Dec 5.

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.023DOI Listing
June 2019
6 Reads
7.216 Impact Factor

Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype.

J Invest Dermatol 2019 Jun 5;139(6):1245-1253. Epub 2018 Dec 5.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.021DOI Listing
June 2019
3 Reads
7.216 Impact Factor

Novel cytokine and chemokine markers of hidradenitis suppurativa reflect chronic inflammation and itch.

Allergy 2019 Mar 10;74(3):631-634. Epub 2018 Dec 10.

Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1111/all.13665
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http://dx.doi.org/10.1111/all.13665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590369PMC
March 2019
47 Reads
6.030 Impact Factor

Making New Connections-Chromosome Conformation Capture for Identification of Disease-Associated Target Genes.

J Invest Dermatol 2019 Mar;139(3):514-517

Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.026DOI Listing
March 2019
1 Read
7.216 Impact Factor

Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.

J Invest Dermatol 2019 Mar 17;139(3):683-691. Epub 2018 Oct 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan USA; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387843PMC
March 2019
3 Reads
7.220 Impact Factor

Research Techniques Made Simple: Using Genome-Wide Association Studies to Understand Complex Cutaneous Disorders.

J Invest Dermatol 2018 03;138(3):e23-e29

Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X183002
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http://dx.doi.org/10.1016/j.jid.2018.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903459PMC
March 2018
3 Reads
7.220 Impact Factor

Fine mapping of eight psoriasis susceptibility loci.

Eur J Hum Genet 2015 Jun 3;23(6):844-53. Epub 2014 Sep 3.

1] Department of Dermatology, University of Michigan, Ann Arbor, MI, USA [2] Ann-Arbor Veteran Affairs Hospital, Ann Arbor, MI, USA.

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http://www.nature.com/doifinder/10.1038/ejhg.2014.172
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http://dx.doi.org/10.1038/ejhg.2014.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795047PMC
June 2015
97 Reads
9 Citations
4.350 Impact Factor

Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model.

Bioinformatics 2015 Apr 4;31(8):1243-9. Epub 2014 Dec 4.

Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA, Department of Dermatology, University of Michigan, Ann Arbor, MI, USA, and Ann Arbor Veterans Affairs Hospital, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393514PMC
April 2015
9 Reads
3 Citations
4.981 Impact Factor

Finding pathway-modulating genes from a novel Ontology Fingerprint-derived gene network.

Nucleic Acids Res 2014 Oct 24;42(18):e138. Epub 2014 Jul 24.

School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA

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http://dx.doi.org/10.1093/nar/gku678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191379PMC
October 2014
10 Reads
3 Citations
9.112 Impact Factor

Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.

Am J Hum Genet 2014 Aug 31;95(2):162-72. Epub 2014 Jul 31.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA; Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129407PMC
August 2014
97 Reads
37 Citations
10.931 Impact Factor

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.

J Invest Dermatol 2014 Jul 17;134(7):1828-1838. Epub 2014 Jan 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954PMC
July 2014
85 Reads
56 Citations
7.220 Impact Factor

Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network.

BMC Syst Biol 2012 17;6 Suppl 3:S3. Epub 2012 Dec 17.

Bioinformatics Graduate Program, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1186/1752-0509-6-S3-S3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524013PMC
June 2013
4 Reads
7 Citations
2.440 Impact Factor

β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo.

Mol Endocrinol 2013 Feb 11;27(2):296-314. Epub 2013 Jan 11.

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1210/me.2012-1091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683806PMC
February 2013
13 Reads
21 Citations
4.022 Impact Factor

Consistent Differential Expression Pattern (CDEP) on microarray to identify genes related to metastatic behavior.

BMC Bioinformatics 2011 Nov 11;12:438. Epub 2011 Nov 11.

Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1186/1471-2105-12-438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251006PMC
November 2011
2 Reads
4 Citations
2.580 Impact Factor

Philometrids of the southern flounder Paralichthys lethostigma: a multidimensional approach to determine their diversity.

J Parasitol 2011 Jun 11;97(3):466-75. Epub 2011 Jan 11.

Department of Biology, College of Charleston, Fort Johnson Road, Charleston, South Carolina 29412, USA.

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http://dx.doi.org/10.1645/GE-2564.1DOI Listing
June 2011
13 Reads
2 Citations
1.260 Impact Factor

Text-mining approach to evaluate terms for ontology development.

J Biomed Inform 2009 Oct 24;42(5):824-30. Epub 2009 Mar 24.

Bioinformatics Graduate Program, Department of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, 135 Cannon Street, Suite 303, Charleston, SC 29424, USA.

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http://dx.doi.org/10.1016/j.jbi.2009.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153945PMC
October 2009
28 Reads
1 Citation
2.482 Impact Factor

Evaluation of genome-wide association study results through development of ontology fingerprints.

Bioinformatics 2009 May 5;25(10):1314-20. Epub 2009 Apr 5.

Bioinformatics Graduate Program, Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732313PMC
May 2009
21 Reads
9 Citations
4.981 Impact Factor

Development of the philometrids Philometra overstreeti and philometroides paralichthydis in the experimentally infected copepod Oithona colcarva.

Folia Parasitol (Praha) 2008 Dec;55(4):313-5

Department of Biology, College of Charleston, 58 Coming St., Charleston, South Carolina 29401, USA.

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http://dx.doi.org/10.14411/fp.2008.040DOI Listing
December 2008
8 Reads
1.211 Impact Factor

A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis.

Clin Immunol 2008 Oct 9;129(1):19-30. Epub 2008 Aug 9.

Department of Medicine, Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1016/j.clim.2008.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562591PMC
October 2008
4 Reads
13 Citations
3.672 Impact Factor

A method of microarray data storage using array data type.

Comput Biol Chem 2007 Apr 12;31(2):143-7. Epub 2007 Jan 12.

Bioinformatics Graduate Program, College of Graduate Study, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1016/j.compbiolchem.2007.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709412PMC
April 2007
2 Reads
1.120 Impact Factor

Top co-authors

James T Elder
James T Elder

University of Michigan

18
Johann E Gudjonsson
Johann E Gudjonsson

University of Michigan

13
Philip E Stuart
Philip E Stuart

University of Michigan

9
Rajan P Nair
Rajan P Nair

University of Michigan

9
John J Voorhees
John J Voorhees

University of Michigan Medical School

8
Andre Franke
Andre Franke

Institute of Clinical Molecular Biology

7
Trilokraj Tejasvi
Trilokraj Tejasvi

All India Institute of Medical Sciences

7
Proton Rahman
Proton Rahman

Memorial University of Newfoundland

6
Stephan Weidinger
Stephan Weidinger

Technical University Munich

6
Dafna D Gladman
Dafna D Gladman

University of Toronto

5