Lalitha Guruprasad

Lalitha Guruprasad

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Lalitha Guruprasad

Lalitha Guruprasad

Publications by authors named "Lalitha Guruprasad"

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Activity and thermal stability of Mycobacterium tuberculosis PE1 and PE2 proteins esterase domain in the presence of aprotic ionic liquids.

Spectrochim Acta A Mol Biomol Spectrosc 2020 Jan 19;225:117477. Epub 2019 Aug 19.

School of Chemistry, University of Hyderabad, Hyderabad, Telangana 500046, India. Electronic address:

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http://dx.doi.org/10.1016/j.saa.2019.117477DOI Listing
January 2020

Covalent Aurora A regulation by the metabolic integrator coenzyme A.

Redox Biol 2020 Jan 5;28:101318. Epub 2019 Sep 5.

Department of Structural and Molecular Biology, University College London, London, WC1E 6BT, UK; Department of Cell Signaling, Institute of Molecular Biology and Genetics, Kyiv 143, Ukraine. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812009PMC
January 2020

Inhibitor binding studies of MraY (Rv21 56c): Insights from molecular modeling, docking, and simulation studies.

J Biomol Struct Dyn 2019 Sep 24;37(14):3751-3763. Epub 2018 Dec 24.

a School of Chemistry , University of Hyderabad , Hyderabad , India.

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http://dx.doi.org/10.1080/07391102.2018.1526715DOI Listing
September 2019

Structural insights into the inhibitor binding and new inhibitor design to Polo-like kinase-1 Polo-box domain using computational studies.

J Biomol Struct Dyn 2019 Aug 1;37(13):3410-3421. Epub 2018 Nov 1.

a School of Chemistry , University of Hyderabad , Hyderabad , India.

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https://www.tandfonline.com/doi/full/10.1080/07391102.2018.1
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http://dx.doi.org/10.1080/07391102.2018.1515663DOI Listing
August 2019

A structural and functional perspective on the enzymes of Mycobacterium tuberculosis involved in the L-rhamnose biosynthesis pathway.

Prog Biophys Mol Biol 2019 08 11;145:52-64. Epub 2018 Dec 11.

School of Chemistry, University of Hyderabad, Hyderabad, Telangana, 500046, India. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2018.12.004DOI Listing
August 2019

Homology modeling, docking and structure-based virtual screening for new inhibitor identification of heptosyltransferase-III.

J Biomol Struct Dyn 2019 Jun 8:1-16. Epub 2019 Jun 8.

a School of Chemistry , University of Hyderabad , Hyderabad , India.

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http://dx.doi.org/10.1080/07391102.2019.1624296DOI Listing
June 2019

Adaptation of Mge1 to oxidative stress by local unfolding and altered Interaction with mitochondrial Hsp70 and Mxr2.

Mitochondrion 2019 05 9;46:140-148. Epub 2018 Apr 9.

Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad 500046, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15677249173034
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http://dx.doi.org/10.1016/j.mito.2018.04.003DOI Listing
May 2019

Mycobacterium tuberculosis PE1 and PE2 proteins carrying conserved α/β-serine hydrolase domain are esterases hydrolyzing short to medium chain p-nitrophenyl esters.

Prog Biophys Mol Biol 2018 12 8;140:90-102. Epub 2018 May 8.

School of Chemistry, University of Hyderabad, Hyderabad, Telangana, 500046, India. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2018.04.012DOI Listing
December 2018

Insights into the carbonic anhydrases and autotrophic carbon dioxide fixation pathways of high CO tolerant Rhodovulum viride JA756.

Microbiol Res 2018 Oct 20;215:130-140. Epub 2018 Jul 20.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, P.O. Central University, Hyderabad, 500 046, India. Electronic address:

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http://dx.doi.org/10.1016/j.micres.2018.07.006DOI Listing
October 2018

Discovery of novel inhibitors of Mycobacterium tuberculosis MurG: homology modelling, structure based pharmacophore, molecular docking, and molecular dynamics simulations.

J Biomol Struct Dyn 2018 Sep 17;36(12):3184-3198. Epub 2017 Oct 17.

a School of Chemistry , University of Hyderabad , Hyderabad 500046 , India.

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http://dx.doi.org/10.1080/07391102.2017.1384398DOI Listing
September 2018

N6-Adenosine DNA Methyltransferase from H. pylori 98-10 Strain in Complex with DNA and AdoMet: Structural Insights from in Silico Studies.

J Phys Chem B 2017 01 5;121(2):365-378. Epub 2017 Jan 5.

School of Chemistry, University of Hyderabad , Hyderabad 500046, India.

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http://dx.doi.org/10.1021/acs.jpcb.6b08433DOI Listing
January 2017

A Single Point Mutation in Mitochondrial Hsp70 Cochaperone Mge1 Gains Thermal Stability and Resistance.

Biochemistry 2016 12 15;55(51):7065-7072. Epub 2016 Dec 15.

Department of Biochemistry, School of Life Sciences, University of Hyderabad , Hyderabad 500046, T.S., India.

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http://dx.doi.org/10.1021/acs.biochem.6b00232DOI Listing
December 2016

Structure and dynamics of H. pylori 98-10 C5-cytosine specific DNA methyltransferase in complex with S-adenosyl-l-methionine and DNA.

Mol Biosyst 2016 10 29;12(10):3111-23. Epub 2016 Jul 29.

School of Chemistry, University of Hyderabad, Hyderabad, 500046, India.

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http://xlink.rsc.org/?DOI=C6MB00306K
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http://dx.doi.org/10.1039/c6mb00306kDOI Listing
October 2016

A transcriptional repressive role for epithelial-specific ETS factor ELF3 on oestrogen receptor alpha in breast cancer cells.

Biochem J 2016 Apr 26;473(8):1047-61. Epub 2016 Feb 26.

Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad 500046, Telangana, India

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http://dx.doi.org/10.1042/BCJ20160019DOI Listing
April 2016

In silico 3D structure modeling and inhibitor binding studies of human male germ cell-associated kinase.

J Biomol Struct Dyn 2015 27;33(8):1710-9. Epub 2014 Oct 27.

a School of Chemistry , University of Hyderabad , Hyderabad 500046 , India.

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http://dx.doi.org/10.1080/07391102.2014.968622DOI Listing
February 2016

Structure based annotation of Helicobacter pylori strain 26695 proteome.

PLoS One 2014 30;9(12):e115020. Epub 2014 Dec 30.

School of Chemistry, University of Hyderabad, Hyderabad, 500046, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115020PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280198PMC
January 2016

Structure and sequence based analysis of alpha-amylase evolution.

Protein Pept Lett 2014 ;21(9):948-56

School of Chemistry, University of Hyderabad, Hyderabad, 500046, India.

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http://dx.doi.org/10.2174/092986652109140715124139DOI Listing
March 2015

Ponatinib is a pan-BCR-ABL kinase inhibitor: MD simulations and SIE study.

PLoS One 2013 13;8(11):e78556. Epub 2013 Nov 13.

School of Chemistry, University of Hyderabad, Hyderabad, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078556PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827254PMC
September 2014

Mutagenesis and molecular dynamics simulations revealed the chitooligosaccharide entry and exit points for chitinase D from Serratia proteamaculans.

Biochim Biophys Acta 2014 Sep 25;1840(9):2685-94. Epub 2014 Jun 25.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad 500046, A.P., India. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2014.06.014DOI Listing
September 2014

Purification and characterization of a stable Kunitz trypsin inhibitor from Trigonella foenum-graecum (fenugreek) seeds.

Phytochemistry 2013 Dec 1;96:26-36. Epub 2013 Oct 1.

School of Chemistry, University of Hyderabad, Hyderabad 500046, India. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2013.09.010DOI Listing
December 2013

Human resistin, a proinflammatory cytokine, shows chaperone-like activity.

Proc Natl Acad Sci U S A 2013 Dec 26;110(51):20467-72. Epub 2013 Nov 26.

Dr. Reddy's Institute of Life Sciences, University of Hyderabad, Hyderabad 500046, India.

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http://dx.doi.org/10.1073/pnas.1306145110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870731PMC
December 2013

Structural basis for binding of aurora-AG198N- INCENP complex: MD simulations and free energy calculations.

Protein Pept Lett 2013 Nov;20(11):1246-56

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

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http://dx.doi.org/10.2174/09298665113209990045DOI Listing
November 2013

Transglycosylation by chitinase D from Serratia proteamaculans improved through altered substrate interactions.

J Biol Chem 2012 Dec 31;287(53):44619-27. Epub 2012 Oct 31.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad-500046, A.P., India.

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http://dx.doi.org/10.1074/jbc.M112.400879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531777PMC
December 2012

Ligand-based 3-D pharmacophore generation and molecular docking of mTOR kinase inhibitors.

J Mol Model 2012 Apr 30;18(4):1611-24. Epub 2011 Jul 30.

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

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http://dx.doi.org/10.1007/s00894-011-1184-3DOI Listing
April 2012

3D-QSAR and molecular docking studies on substituted isothiazole analogs as inhibitors against MEK-1 kinase.

Chem Biol Drug Des 2012 Jan 8;79(1):84-91. Epub 2011 Nov 8.

School of Chemistry, University of Hyderabad, Hyderabad, Andhra Pradesh, India.

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http://dx.doi.org/10.1111/j.1747-0285.2011.01250.xDOI Listing
January 2012

3D-QSAR and molecular docking studies of 2-pyrimidinecarbonitrile derivatives as inhibitors against falcipain-3.

Bioorg Med Chem Lett 2011 Dec 1;21(23):7219-23. Epub 2011 Oct 1.

School of Chemistry, University of Hyderabad, Hyderabad, India.

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http://dx.doi.org/10.1016/j.bmcl.2011.09.107DOI Listing
December 2011

The Rv3799-Rv3807 gene cluster in Mycobacterium tuberculosis genome corresponds to the 'Ancient Conserved Region' in CMN mycolyltransferases.

Evol Bioinform Online 2006 27;2:377-85. Epub 2007 Feb 27.

School of Chemistry, University of Hyderabad, Hyderabad 500 046, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089981PMC
November 2011

Structural rationale for the recognition of arginine at P₃ in PEXEL motif containing proteins of Plasmodium falciparum by plasmepsin V.

Protein Pept Lett 2011 Jun;18(6):634-41

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

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http://dx.doi.org/10.2174/092986611795222786DOI Listing
June 2011

Highly conserved Asp-204 and Gly-776 are important for activity of the quinoprotein glucose dehydrogenase of Escherichia coli and for mineral phosphate solubilization.

J Mol Microbiol Biotechnol 2010 10;18(2):109-19. Epub 2010 Mar 10.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Central University, Hyderabad, India.

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http://dx.doi.org/10.1159/000293819DOI Listing
June 2010

Structure prediction of neuroendocrine convertase -2: a potential target in various cancers.

Protein Pept Lett 2009 ;16(4):383-91

School of Life Sciences, University of Hyderabad, Hyderabad 500 046, India.

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http://www.eurekaselect.com/openurl/content.php?genre=articl
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http://dx.doi.org/10.2174/092986609787848018DOI Listing
June 2009

Interaction of bovine serum albumin with dipolar molecules: fluorescence and molecular docking studies.

J Phys Chem B 2009 Feb;113(7):2143-50

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

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http://dx.doi.org/10.1021/jp808611bDOI Listing
February 2009

Prokaryotic expression of a constitutively expressed Tephrosia villosa defensin and its potent antifungal activity.

Appl Microbiol Biotechnol 2008 Oct 23;80(6):1023-32. Epub 2008 Aug 23.

Department of Plant Sciences, University of Hyderabad, Hyderabad, India.

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http://dx.doi.org/10.1007/s00253-008-1648-2DOI Listing
October 2008

Homology modeling of 5-lipoxygenase and hints for better inhibitor design.

J Comput Aided Mol Des 2008 Sep 30;22(9):611-9. Epub 2008 Jan 30.

School of Life Sciences, University of Hyderabad, Hyderabad, 500 046, India.

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http://link.springer.com/10.1007/s10822-008-9180-0
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http://dx.doi.org/10.1007/s10822-008-9180-0DOI Listing
September 2008

Molecular, biochemical and structural characterization of osmotin-like protein from black nightshade (Solanum nigrum).

J Plant Physiol 2007 Mar 20;164(3):238-52. Epub 2006 Mar 20.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad 500046, AP, India.

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http://dx.doi.org/10.1016/j.jplph.2006.01.006DOI Listing
March 2007

Juxtaposed half-cystines as disulphide bridged partners in protein tertiary structure.

Protein Pept Lett 2006 ;13(6):577-9

Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad - 500 007, India.

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http://dx.doi.org/10.2174/092986606777145841DOI Listing
September 2006

Analysis and modeling of mycolyl-transferases in the CMN group.

Bioinformation 2006 Jun 18;1(5):161-9. Epub 2006 Jun 18.

School of Chemistry, University of Hyderabad, Hyderabad - 500046, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891678PMC
http://dx.doi.org/10.6026/97320630001161DOI Listing
June 2006

Three-dimensional models and structure analysis of corynemycolyltransferases in Corynebacterium glutamicum and Corynebacterium efficiens.

Int J Biol Macromol 2004 Jun;34(3):181-9

School of Chemistry, University of Hyderabad, Hyderabad 500 046, India.

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http://dx.doi.org/10.1016/j.ijbiomac.2004.03.008DOI Listing
June 2004

Sequence analysis corresponding to the PPE and PE proteins in Mycobacterium tuberculosis and other genomes.

J Biosci 2003 Mar;28(2):169-79

School of Chemistry, University of Hyderabad, Hyderabad 500 046, India.

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http://dx.doi.org/10.1007/bf02706216DOI Listing
March 2003