Lakshmi Nayak

Lakshmi Nayak

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Lakshmi Nayak

Publications by authors named "Lakshmi Nayak"

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Integration of rare cell capture technology into cytologic evaluation of cerebrospinal fluid specimens from patients with solid tumors and suspected leptomeningeal metastasis.

J Am Soc Cytopathol 2019 Sep 11. Epub 2019 Sep 11.

Department of Pathology, Stanford University, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.jasc.2019.09.001DOI Listing
September 2019

Central Nervous System Lymphoma.

Hematol Oncol Clin North Am 2019 Aug 10;33(4):597-611. Epub 2019 May 10.

Department of Medical Oncology, Center for Neuro-Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2019.03.008DOI Listing
August 2019

Is it time to revisit R-CHOP for primary CNS lymphoma?

Blood 2019 Jul;134(3):221-222

Brigham and Women's Hospital.

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http://dx.doi.org/10.1182/blood.2019001383DOI Listing
July 2019

Introduction of novel agents in the treatment of primary CNS lymphoma.

Neuro Oncol 2019 Feb;21(3):306-313

Departments of Neurology and Radiation Oncology, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts.

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https://academic.oup.com/neuro-oncology/advance-article/doi/
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http://dx.doi.org/10.1093/neuonc/noy193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380407PMC
February 2019

Brain metastases.

Nat Rev Dis Primers 2019 01 17;5(1). Epub 2019 Jan 17.

Department of Neurosurgery, University of California-Davis, School of Medicine, Sacramento, CA, USA.

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http://www.nature.com/articles/s41572-018-0055-y
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http://dx.doi.org/10.1038/s41572-018-0055-yDOI Listing
January 2019

Evolving Treatments for Primary Central Nervous System Lymphoma.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:454-466. Epub 2019 May 17.

4 University of California, San Francisco, CA.

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https://ascopubs.org/doi/10.1200/EDBK_242547
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http://dx.doi.org/10.1200/EDBK_242547DOI Listing
January 2019

PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma.

Neurology 2018 10 31;91(14):e1355-e1359. Epub 2018 Aug 31.

From the Laura and Isaac Perlmutter Cancer Center (S.C.K.), Brain Tumor Center, NYU Langone Medical Center, New York; Dana-Farber Cancer Institute (L.P.C., D.H., M.R., L.N., E.Q.L., D.A.R., P.Y.W.), Center for Neuro-Oncology; and Department of Radiology (R.H., P.U.), Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000006283DOI Listing
October 2018

Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative.

Lancet Oncol 2018 03;19(3):e173-e180

Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; Department of Neurology, Haaglanden Medical Center, The Hague, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30004-4DOI Listing
March 2018

High-grade Gliomas.

Continuum (Minneap Minn) 2017 Dec;23(6, Neuro-oncology):1548-1563

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http://dx.doi.org/10.1212/CON.0000000000000554DOI Listing
December 2017

A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy.

Neuro Oncol 2016 06 21;18(6):849-54. Epub 2016 Feb 21.

Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (E.Q.L., D.A.R., A.D.N., L.N., M.L.R., B.M.A., N.D.A., L.D., J.S., D.L., S.F.R., J.P., K.H.S., S.C.G., S.H., P.Y.W.); Harvard Medical School, Boston, Massachusetts (E.Q.L., E.T.W., D.A.R., A.D.N., L.N., M.L.R., B.M.A., N.D.A., P.Y.W.); Massachusetts General Hospital, Boston, Massachusetts (A.M.); University of Pittsburgh, Pittsburgh, Pennsylvania (J.D.); University of California San Diego, La Jolla, California (S.K.); Beth Israel Deaconess Medical Center, Boston, Massachusetts (E.T.W.); Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire (C.E.F.); Geisel School of Medicine at Dartmouth, Hanover, New Hampshire (C.E.F.).

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http://dx.doi.org/10.1093/neuonc/now007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864265PMC
June 2016

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study.

Neuro Oncol 2016 Apr 8;18(4):557-64. Epub 2015 Oct 8.

University of California at San Francisco, San Francisco, California (N.B., A.P., J.P., A.M.M, M.P.); Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah (H.C.); The University of Texas MD Anderson Cancer Center, Houston, Texas (J.F.D.G.); Department of Neurology, Memorial Sloan Kettering Cancer Hospital, New York, New York (A.M.O.); Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (L.N., P.Y.W., S.H., K.L.L.); UCLA Medical Center, Los Angeles, California (T.F.C.); Plexxikon Inc., Berkeley, California (A.M., B.L.W., K.B.N., H.H.H.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (K.L.L.); Department of Pathology, Memorial Sloan Kettering Cancer Hospital, New York, New York (J.H.).

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http://dx.doi.org/10.1093/neuonc/nov245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799682PMC
April 2016

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma.

Neuro Oncol 2016 Feb 30;18(2):269-74. Epub 2015 Aug 30.

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (A.A.A., M.C.H., N.D.A., B.M.A.); Department of Pathology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (M.A., K.L.L., A.H.L., S.S.); Department of Neurosurgery, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (W.L.B., O.A-M., I.F.D.); Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (E.Q.L., L.N., M.L.R., A.D.N., D.A.R., P.Y.W., R.B.).

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nov177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724184PMC
February 2016

Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.

Neuro Oncol 2015 Oct 9;17(10):1344-55. Epub 2015 Mar 9.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.H.R., L.A.R., S.H., D.K., Y.J.K., K.L.L.); Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.E.S., L.B., M.B., D.A.R., E.Q.L., M.L.R., A.D.N., L.N., S.R., L.M.D., D.C.L., P.K., B.J.R., P.Y.W., R.B., K.L.L.); Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts (W.L.B., E.B.C, O.A.-M., M.D.J., A.J.G., I.F.D., E.A.C.); Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts (L.T.); Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Massachusetts (M.H., A.A.A., N.D.A., B.M.A.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (M.H., A.A.A., N.D.A., B.M.A.); Harvard Radiation Oncology Program, Boston, Massachusetts (A.R.); Kravis Center for Molecular Oncology & Department of Epidemiology and Biostatistics, Memorial Sloan- Kettering Cancer Center, New York, New York (N.S.); Broad Institute, Cambridge, Massachusetts (R.B.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.H.R., A.D., J.B.C., M.A., S.S., R.D.F., N.I.L., A.H.L., K.L.L.)

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http://dx.doi.org/10.1093/neuonc/nov015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578577PMC
October 2015

Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.

J Clin Oncol 2015 Oct 17;33(28):3186-92. Epub 2015 Aug 17.

Mrinal M. Gounder, Armando J. Sanchez, and Lisa M. DeAngelis, Memorial Sloan-Kettering Cancer Center and Weil Cornell Medical School, New York, NY; Lakshmi Nayak and Patrick Y. Wen, Dana-Farber/Brigham and Women's Cancer Center and Harvard Medical School; Alona Muzikansky, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Solmaz Sahebjam, Moffitt Cancer Center, University of South Florida, Tampa, FL; Serena Desideri, Xiaobu Ye, and Stuart Grossman, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore; S. Percy Ivy, National Cancer Institute, Cancer Therapy Evaluation Program, Bethesda, MD; L. Burt Nabors, University of Alabama at Birmingham, Birmingham, AL; and Michael Prados, University of California at San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2015.61.1525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857195PMC
October 2015

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma.

Neuro Oncol 2015 Jun 7;17(6):862-7. Epub 2015 Jan 7.

Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts (E.Q.L., D.A.R., A.D.N., L.N., R.B., M.L.R., K.H., C.M., K.H.S., S.C.G., B.W., K.L.L., P.Y.W.); University of Virginia, Charlottesville, Virginia (D.S.); University of Pittsburgh, Pittsburgh, Pennsylvania (J.D.); Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (A.S.C., T,T.B., A.M.); Central DuPage Hospital, Warrenville, Illinois (S.A.G.); Northwestern University, Chicago, Illinois (J.J.R.).

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http://neuro-oncology.oxfordjournals.org/content/17/6/862.fu
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http://neuro-oncology.oxfordjournals.org/cgi/doi/10.1093/neu
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http://dx.doi.org/10.1093/neuonc/nou350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483124PMC
June 2015

Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients.

Int J Radiat Oncol Biol Phys 2015 Jun 1;92(2):384-9. Epub 2015 Apr 1.

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.01.017DOI Listing
June 2015

Radiotherapy and temozolomide for anaplastic astrocytic gliomas.

J Neurooncol 2015 May 29;123(1):129-34. Epub 2015 Apr 29.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s11060-015-1771-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606458PMC
May 2015

Medical management of brain tumors and the sequelae of treatment.

Neuro Oncol 2015 Apr 30;17(4):488-504. Epub 2014 Oct 30.

Neuro-Oncology Center, University of Virginia Medical Center, Charlottesville, Virginia (D.S.); Center for Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts (E.Q.L., L.N., A.D.N., D.A.R., P.Y.W.).

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http://dx.doi.org/10.1093/neuonc/nou304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483077PMC
April 2015

Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma.

Neuro Oncol 2014 Nov 2;16(11):1547-53. Epub 2014 Jun 2.

Harvard Radiation Oncology Program, Brigham and Women's Hospital, Boston, Massachusetts (A.A.A.); Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (N.D.A., B.M.A.); Department of Biostatistics, Dana-Farber Cancer Institute, Boston, Massachusetts (P.C.); Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts (E.B.C., A.J.G., M.D.J., O.A-M., I.F.D.); Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (P.Y.W., D.A.R., E.Q.L., L.N., M.L.R., R.B.); Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania (S.E.W.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.H.R., S.S., M.A.).

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http://dx.doi.org/10.1093/neuonc/nou098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201070PMC
November 2014

Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab.

Neuro Oncol 2014 Nov 23;16(11):1523-9. Epub 2014 Jun 23.

Harvard Medical School, Boston, Massachusetts (R.R., A.D.N., D.A.R., L.N., M.L.R., R.B., B.M.A., R.Y.H., P.Y.W., E.Q.L.); Center of Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (K.H., A.D.N., D.A.R., L.N., M.L.R., R.B., L.D., S.R., J.R., D.L., P.Y.W., E.Q.L.); Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts (A.D.N., D.A.R., L.N., M.L.R., R.B., P.Y.W., E.Q.L.); Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Massachusetts (B.M.A.); Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts (R.Y.H.); Boston University School of Medicine, Boston, Massachusetts (A.R.).

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http://dx.doi.org/10.1093/neuonc/nou118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201074PMC
November 2014

The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.

J Neurooncol 2014 Jul 17;118(3):501-55. Epub 2014 Apr 17.

Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA,

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http://link.springer.com/10.1007/s11060-013-1338-5
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http://dx.doi.org/10.1007/s11060-013-1338-5DOI Listing
July 2014

The role of targeted therapies in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.

J Neurooncol 2014 Jul 17;118(3):557-99. Epub 2014 Apr 17.

Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA,

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http://dx.doi.org/10.1007/s11060-013-1339-4DOI Listing
July 2014

Recent advances in treatment of primary central nervous system lymphoma.

Curr Treat Options Oncol 2013 Dec;14(4):539-52

Dana-Farber Cancer Institute, Center for Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s11864-013-0252-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841579PMC
December 2013

Retrospective study of pemetrexed as salvage therapy for central nervous system lymphoma.

J Neurooncol 2013 Oct 5;115(1):71-7. Epub 2013 Jul 5.

Department of Neuro-Oncology, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1007/s11060-013-1196-1DOI Listing
October 2013

Treatment options in newly diagnosed glioblastoma.

Curr Treat Options Neurol 2013 Jun;15(3):281-8

Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s11940-013-0226-9DOI Listing
June 2013

Update on bevacizumab and other angiogenesis inhibitors for brain cancer.

Expert Opin Emerg Drugs 2013 Jun 14;18(2):137-53. Epub 2013 May 14.

Dana-Farber/Brigham and Women's Cancer Center, Center for Neuro-Oncology, Boston, MA, USA.

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http://dx.doi.org/10.1517/14728214.2013.794784DOI Listing
June 2013

PCV for anaplastic oligodendrogliomas: back to the future or a step backwards? A point/counterpoint discussion.

J Neurooncol 2013 May 12;113(1):143-7. Epub 2013 Mar 12.

Department of Internal Medicine and Markey Cancer Center, University of Kentucky, Lexington, KY, USA.

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http://link.springer.com/10.1007/s11060-013-1100-z
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http://dx.doi.org/10.1007/s11060-013-1100-zDOI Listing
May 2013

Rare cell capture technology for the diagnosis of leptomeningeal metastasis in solid tumors.

Neurology 2013 Apr 3;80(17):1598-605; discussion 1603. Epub 2013 Apr 3.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1212/WNL.0b013e31828f183fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662321PMC
April 2013

Atypical and anaplastic meningiomas treated with bevacizumab.

J Neurooncol 2012 Aug 29;109(1):187-93. Epub 2012 Apr 29.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s11060-012-0886-4DOI Listing
August 2012

Use of recombinant tissue plasminogen activator in cancer patients with acute stroke.

J Neurooncol 2012 May 18;107(3):571-3. Epub 2011 Dec 18.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://link.springer.com/10.1007/s11060-011-0780-5
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http://dx.doi.org/10.1007/s11060-011-0780-5DOI Listing
May 2012

Epidemiology of brain metastases.

Curr Oncol Rep 2012 Feb;14(1):48-54

Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, 450 Brookline Avenue, SW-430D, Boston, MA 02215, USA.

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http://link.springer.com/10.1007/s11912-011-0203-y
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http://dx.doi.org/10.1007/s11912-011-0203-yDOI Listing
February 2012

Late relapse in primary central nervous system lymphoma: clonal persistence.

Neuro Oncol 2011 May 3;13(5):525-9. Epub 2011 Mar 3.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nor014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093334PMC
May 2011

Primary brain tumors in the elderly.

Curr Neurol Neurosci Rep 2010 Jul;10(4):252-8

Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s11910-010-0110-xDOI Listing
July 2010

Prognosis and patterns of care in elderly patients with glioma.

Cancer 2009 Dec;115(23):5534-40

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1002/cncr.24612DOI Listing
December 2009

Glioblastoma in the elderly: the Memorial Sloan-Kettering Cancer Center Experience (1997-2007).

Cancer 2009 Aug;115(16):3758-66

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://doi.wiley.com/10.1002/cncr.24413
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http://dx.doi.org/10.1002/cncr.24413DOI Listing
August 2009

Intracranial dural metastases.

Cancer 2009 May;115(9):1947-53

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1002/cncr.24203DOI Listing
May 2009

Amphiphysin autoimmunity in paraneoplastic neurologic disease.

Clin Adv Hematol Oncol 2009 Mar;7(3):183-4

Department of Neurology and Neuroscience, Weill Cornell Medical College, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, NY 10021, USA.

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March 2009

Rasagiline in treatment of Parkinson's disease.

Neuropsychiatr Dis Treat 2008 Feb;4(1):23-32

Department of Neurology, Weill Medical College of Cornell University New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515917PMC
February 2008