Lakhmir S Chawla

Lakhmir S Chawla

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Use of Cell Cycle Arrest Biomarkers in Conjunction With Classical Markers of Acute Kidney Injury.

Crit Care Med 2019 10;47(10):e820-e826

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of, Pittsburgh, Pittsburgh PA.

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http://dx.doi.org/10.1097/CCM.0000000000003907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750148PMC
October 2019

Serial Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 and the Prognosis for Acute Kidney Injury over the Course of Critical Illness.

Cardiorenal Med 2019 Oct 16:1-12. Epub 2019 Oct 16.

Center for Critical Care Nephrology, Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1159/000502837DOI Listing
October 2019

Acute Kidney Injury Recovery.

Contrib Nephrol 2018 23;193:35-44. Epub 2018 Jan 23.

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http://dx.doi.org/10.1159/000484961DOI Listing
April 2019

Therapeutic Opportunities for Hepcidin in Acute Care Medicine.

Crit Care Clin 2019 Apr 30;35(2):357-374. Epub 2019 Jan 30.

La Jolla Pharmaceutical Company, 4550 Towne Centre Court, San Diego, CA 92121, USA; Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1016/j.ccc.2018.11.014DOI Listing
April 2019

The authors reply.

Crit Care Med 2019 Mar;47(3):e271-e272

School of Medicine, The University of Melbourne, Melbourne, VIC, Australia La Jolla Pharmaceutical Company, San Diego, CA.

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http://dx.doi.org/10.1097/CCM.0000000000003601DOI Listing
March 2019

Response.

Chest 2019 01;155(1):242-243

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN; Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183243
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http://dx.doi.org/10.1016/j.chest.2018.08.1069DOI Listing
January 2019

Global epidemiology and outcomes of acute kidney injury.

Nat Rev Nephrol 2018 10;14(10):607-625

VA Medical Center, Department of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1038/s41581-018-0052-0DOI Listing
October 2018

Angiotensin converting enzyme defects in shock: implications for future therapy.

Crit Care 2018 10 28;22(1):274. Epub 2018 Oct 28.

La Jolla Pharmaceutical Company, 4550 Towne Centre Court, San Diego, CA, 92121, USA.

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-2202-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204272PMC
October 2018

Management of Refractory Vasodilatory Shock.

Chest 2018 08 9;154(2):416-426. Epub 2018 Jan 9.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.chest.2017.12.021DOI Listing
August 2018

Drug management in acute kidney disease - Report of the Acute Disease Quality Initiative XVI meeting.

Br J Clin Pharmacol 2018 02 1;84(2):396-403. Epub 2017 Dec 1.

Cincinnati Children's Hospital Medical Center, Division of Nephrology and Hypertension, Cincinnati, USA.

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http://doi.wiley.com/10.1111/bcp.13449
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http://dx.doi.org/10.1111/bcp.13449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777429PMC
February 2018

Sequelae of AKI.

Best Pract Res Clin Anaesthesiol 2017 Sep 6;31(3):415-425. Epub 2017 Sep 6.

The Veterans Affairs Medical Center, Washington, DC, USA; George Washington University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.bpa.2017.08.004DOI Listing
September 2017

Clinical Experience With IV Angiotensin II Administration: A Systematic Review of Safety.

Crit Care Med 2017 Aug;45(8):1285-1294

1Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, Emory St. Joseph's Hospital, Atlanta, GA.2Division of Critical Care, Department of Anesthesia, Duke University Medical Center, Durham, NC.3Department of Medicine, Thomas Jefferson University, Philadelphia, PA.4Division of Renal Diseases and Hypertension, Department of Medicine, University of Texas Health Science Center, Houston, TX.5Anesthesiology Institute, Center for Critical Care and Department of Outcomes Research, Cleveland Clinic Foundation, Cleveland, OH.6Division of Nephrology, Department of Medicine, Baylor University Medical Center, Dallas, TX.7Department of Medicine, University of Maryland Medical Center, Baltimore, MD.8La Jolla Pharmaceutical Company, San Diego, CA.9Division of Intensive Care Medicine and Division of Nephrology, Department of Medicine, Veterans Affairs Medical Center, Washington, DC.

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http://dx.doi.org/10.1097/CCM.0000000000002441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515638PMC
August 2017

Angiotensin II for the Treatment of Vasodilatory Shock.

N Engl J Med 2017 08 21;377(5):419-430. Epub 2017 May 21.

From Anesthesiology Institute, Center for Critical Care and Department of Outcomes Research, Cleveland Clinic, Cleveland (A.K.); the Department of Medicine (Critical Care), University of Ottawa, and the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (S.W.E.); Division of Critical Care Medicine, Department of Anesthesiology, Duke University Medical Center, Durham, NC (X.S.W.); Regions Hospital, St. Paul, MN (K.H.); University of Tennessee College of Medicine, Chattanooga (J.T.); the Division of Nephrology, Baylor University Medical Center, Dallas (H.S.); the Department of Medicine, Emory University School of Medicine, Atlanta (L.W.B.); Inova Medical Center, Falls Church, VA (L.A.); the Department of Internal Medicine, University of California Davis School of Medicine, Sacramento (T.E.A.), the Division of Critical Care, Department of Anesthesiology, University of California Los Angeles, Los Angeles (D.W.B.), and La Jolla Pharmaceutical Company, San Diego (J.J., S.K., L.S.C., G.F.T.) - all in California; the Department of Pulmonary and Critical Care Medicine, Riverside Methodist Hospital, Columbus, OH (C.M.); the Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore (M.T.M.); the Department of Surgery, Sunrise Hospital, Las Vegas (S.C.); Intensive Care Unit, Wellington Hospital, and Medical Research Institute of New Zealand, Wellington, New Zealand (P.J.Y.); the Division of Critical Care, Department of Medicine, Eastern Idaho Regional Medical Center, Idaho Falls (K.K.); the Department of Medicine, Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago (R.G.W.); the Department of Critical Care and Nephrology, King's College London, Guy's and St. Thomas' Hospital, London (M.O.); the Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh (R.M.); the Department of Medicine, Albert Einstein College of Medicine, and the Division of Critical Care Medicine, Montefiore Medical Center, Bronx, NY (M.N.G.); John Hunter Hospital, New Lambton Heights, and School of Medicine and Public Health, University of Newcastle, Callaghan, NSW (R.P.), the Department of Intensive Care, Wesley Hospital and Princess Alexandra Hospital, University of Queensland, St Lucia (B.V.), and School of Medicine, University of Melbourne, Parkville (R.B.), and the Intensive Care Unit, the Royal Melbourne Hospital, University of Melbourne (A.M.D.), Melbourne, VIC - all in Australia; the Division of Intensive Care Medicine, Department of Anesthesiology, Intensive Care, and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki (J.H.); INSERM UMR 995 LIRIC (Lille Inflammation Research Center), Centre Hospitalier Universitaire Lille, Critical Care Center and University of Lille School of Medicine, Lille, France (R.F.); and the Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (B.T.T.).

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http://dx.doi.org/10.1056/NEJMoa1704154DOI Listing
August 2017

Characterization of end-of-life electroencephalographic surges in critically ill patients.

Death Stud 2017 07 1;41(6):385-392. Epub 2017 Feb 1.

c Department of Anesthesiology and Critical Care Medicine , George Washington University Medical Center , Washington , DC , USA.

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http://dx.doi.org/10.1080/07481187.2017.1287138DOI Listing
July 2017

Understanding renal recovery.

Intensive Care Med 2017 06 23;43(6):924-926. Epub 2017 Mar 23.

Division of Nephrology, St. Michael's Hospital and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1007/s00134-017-4773-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487603PMC
June 2017

Impact of Acute Kidney Injury in Patients Hospitalized With Pneumonia.

Crit Care Med 2017 Apr;45(4):600-606

1Department of Medicine, Veterans Affairs Medical Center, Washington, DC.2Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University Medical Center, Washington, DC.3Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, DC.4Department of Surgery, George Washington University Medical Center, Washington, DC.5National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/CCM.0000000000002245DOI Listing
April 2017

Recovery after Acute Kidney Injury.

Am J Respir Crit Care Med 2017 03;195(6):784-791

5 Department of Medicine, Veterans Affairs Medical Center, Washington, DC.

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http://dx.doi.org/10.1164/rccm.201604-0799OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363967PMC
March 2017

Glomerular and Tubular Kidney Stress Test: New Tools for a Deeper Evaluation of Kidney Function.

Nephron 2016 30;134(3):191-194. Epub 2016 Aug 30.

Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy.

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http://dx.doi.org/10.1159/000449235DOI Listing
March 2017

Long-term consequences of acute kidney injury in the perioperative setting.

Curr Opin Anaesthesiol 2017 Feb;30(1):100-104

aDepartment of Medicine bBiostatistics Core Laboratory, Veterans Affairs Medical Center cDivision of Renal Diseases and Hypertension, Department of Surgery, George Washington University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1097/ACO.0000000000000428DOI Listing
February 2017

Long-term Effects of Off-Pump Coronary Bypass Versus Conventional Coronary Bypass Grafting on Renal Function.

Innovations (Phila) 2016 Jan-Feb;11(1):54-8; discussion 58

From the *Division of Cardiothoracic Surgery, Veterans Affairs Medical Center, Washington, DC USA; †Division of Cardiothoracic Surgery, The George Washington University, Washington, DC USA; and Divisions of ‡Critical Care Medicine, and §Cardiology, Veterans Affairs Medical Center, Washington, DC USA.

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http://pdfs.journals.lww.com/innovjournal/2016/01000/Long_te
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IMI.0000000000000224DOI Listing
January 2017

Use of stress tests in evaluating kidney disease.

Curr Opin Nephrol Hypertens 2017 01;26(1):31-35

aSection of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois bDepartment of Medicine, Veterans Affairs Medical Center cDepartment of Medicine, George Washington University, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000292DOI Listing
January 2017

Clinical adjudication in acute kidney injury studies: findings from the pivotal TIMP-2*IGFBP7 biomarker study.

Nephrol Dial Transplant 2016 10 23;31(10):1641-6. Epub 2016 Jun 23.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, USA.

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http://dx.doi.org/10.1093/ndt/gfw238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039343PMC
October 2016

Common chronic conditions do not affect performance of cell cycle arrest biomarkers for risk stratification of acute kidney injury.

Nephrol Dial Transplant 2016 10 23;31(10):1633-40. Epub 2016 Jun 23.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1093/ndt/gfw241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039344PMC
October 2016

Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.

Crit Care Med 2016 Oct;44(10):1851-60

1Department of Intensive Care Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, VUB School of Medicine, Brussels, Belgium.2Department of Medicine, Pulmonary and Critical Care Medicine and Department of Emergency Medicine, Loma Linda University, Loma Linda, CA.3Division of Critical Care Medicine, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.4Department of Medicine, Division of Intensive Care Medicine and Division of Nephrology, Veterans Affairs Medical Center, and Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, DC.5Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.6Critical Care Center, Sabadell Hospital, CIBER de Enfermedades Respiratorias, Corporacó Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, Sabadell, Spain.7Walker Biosciences, Carlsbad, CA.8Department of Anesthesiology and Critical Care Medicine 2, Hospital Haut Leveque, University of Bordeaux 2, Bordeaux, France.9Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.10The Center for Critical Care Nephrology, CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Center, Pittsburgh, PA.11Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000001827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089124PMC
October 2016

High serum creatinine nonlinearity: a renal vital sign?

Am J Physiol Renal Physiol 2016 08 18;311(2):F305-9. Epub 2016 May 18.

Department of Medicine, Veterans Affairs Medical Center, Washington, District of Columbia; Biostatistics Core, Veterans Affairs Medical Center, Washington, District of Columbia; Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia

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http://ajprenal.physiology.org/content/ajprenal/early/2016/0
Web Search
http://ajprenal.physiology.org/lookup/doi/10.1152/ajprenal.0
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http://dx.doi.org/10.1152/ajprenal.00025.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971886PMC
August 2016

Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes.

BMC Med Genomics 2016 07 15;9(1):40. Epub 2016 Jul 15.

Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, 2300 I Street, NW Ross 443, Washington, DC, 20037, USA.

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http://dx.doi.org/10.1186/s12920-016-0200-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946184PMC
July 2016

Predicting acute kidney injury prognosis.

Curr Opin Nephrol Hypertens 2016 May;25(3):226-31

aBaylor University Medical Center, Dallas, Texas bDepartment of Medicine, Veterans Affairs Medical Center, Washington, District of Columbia, C, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000223DOI Listing
May 2016

Renal Stress Testing in the Assessment of Kidney Disease.

Kidney Int Rep 2016 May 5;1(1):57-63. Epub 2016 May 5.

Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy.

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http://dx.doi.org/10.1016/j.ekir.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678605PMC
May 2016

The use of angiotensin II in distributive shock.

Crit Care 2016 May 27;20(1):137. Epub 2016 May 27.

Department of Intensive Care Medicine, Prince Sultan Military City, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.1186/s13054-016-1306-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882778PMC
May 2016

THE EPITHELIUM AS A TARGET IN SEPSIS.

Shock 2016 Mar;45(3):249-58

*Department of Medicine, Veterans Affairs Medical Center, Washington, District of Columbia †Departments of Surgery and Anesthesiology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California ‡Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio §Infectious Disease Division, Alpert Medical School of Brown University, Providence, Rhode Island ||Academia Colombiana de Medicina Critica (ACOMEC) ¶Division of Critical Care Medicine, Clínica Palermo, Bogotá, Colombia #University College Dublin, Dublin, Ireland **Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/SHK.0000000000000518DOI Listing
March 2016

Timing of death after traumatic injury--a contemporary assessment of the temporal distribution of death.

J Surg Res 2016 Feb 28;200(2):604-9. Epub 2015 Aug 28.

Department of Medicine, The George Washington University Hospital, Washington, DC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00224804150087
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http://dx.doi.org/10.1016/j.jss.2015.08.031DOI Listing
February 2016

TIMP2•IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients.

J Trauma Acute Care Surg 2016 Feb;80(2):243-9

From the Departments of Emergency Medicine, Anesthesiology, and Internal Medicine (K.J.G.), Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, Michigan; Department of Anesthesia (A.D.S.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Medicine (L.S.C.), Division of Intensive Care Medicine and Division of Nephrology, Veterans Affairs Medical Center, Washington, District of Columbia; Department of Anesthesiology (A.B), University of Florida, Gainesville, Florida; Center for Critical Care Nephrology (A.A.-K., J.A.K.), Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Pulmonary and Critical Care Medicine (K.K.), Mayo Clinic, Rochester, Minnesota; Department of Surgery (M.L.), University of Maryland School of Maryland, Baltimore, Maryland; and Statistical Consultant (J.S., M.G.W.), Carlsbad, California.

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http://dx.doi.org/10.1097/TA.0000000000000912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729326PMC
February 2016

Cell-cycle arrest and acute kidney injury: the light and the dark sides.

Nephrol Dial Transplant 2016 Jan 4;31(1):16-22. Epub 2015 Jun 4.

Department of Medicine, Division of Intensive Care Medicine and Division of Nephrology, Veterans Affairs Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1093/ndt/gfv130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703048PMC
January 2016

Renal Hemodynamics in AKI: In Search of New Treatment Targets.

J Am Soc Nephrol 2016 Jan 28;27(1):49-58. Epub 2015 Oct 28.

Department of Nephrology Dialysis and Transplantation, San Bortolo Hospital and the International Renal Research Institute, Vicenza, Italy.

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http://dx.doi.org/10.1681/ASN.2015030234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696587PMC
January 2016

Reference intervals of urinary acute kidney injury (AKI) markers [IGFBP7]∙[TIMP2] in apparently healthy subjects and chronic comorbid subjects without AKI.

Clin Chim Acta 2016 Jan 10;452:32-7. Epub 2015 Nov 10.

Department of Pathology, Center for Advanced Laboratory Medicine, University of California-San Diego Health Systems, San Diego, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2015.10.029DOI Listing
January 2016

Demographic data for urinary Acute Kidney Injury (AKI) marker [IGFBP7]·[TIMP2] reference range determinations.

Data Brief 2015 Dec 5;5:888-92. Epub 2015 Nov 5.

Department of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health Systems, San Diego, CA, USA.

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http://dx.doi.org/10.1016/j.dib.2015.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669474PMC
December 2015

Acute kidney injury: gateway to chronic kidney disease.

Nephron Clin Pract 2014 24;127(1-4):30-4. Epub 2014 Sep 24.

Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Mich., USA.

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http://dx.doi.org/10.1159/000363675DOI Listing
October 2015

Acute Kidney Injury and CKD: No Respite for a Weary Kidney.

Am J Kidney Dis 2015 Oct;66(4):552-4

Veterans Affairs Medical Center, Washington, DC. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2015.08.014DOI Listing
October 2015

A Clinical Approach to the Acute Cardiorenal Syndrome.

Crit Care Clin 2015 Oct;31(4):685-703

Division of Intensive Care Medicine, Department of Medicine, Washington DC Veterans Affairs Medical Center, 50 Irving Street, Washington, DC 20422, USA; Division of Nephrology, Department of Medicine, Washington DC Veterans Affairs Medical Center, 50 Irving Street, Washington, DC 20422, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccc.2015.06.006DOI Listing
October 2015

Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity.

J Am Soc Nephrol 2015 Aug 5;26(8):2023-31. Epub 2015 Feb 5.

Department of Medicine, Division of Intensive Care Medicine and Division of Nephrology, Washington DC Veterans Affairs Medical Center, Washington, DC

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http://dx.doi.org/10.1681/ASN.2014060535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520172PMC
August 2015

Tissue Inhibitor Metalloproteinase-2 (TIMP-2)⋅IGF-Binding Protein-7 (IGFBP7) Levels Are Associated with Adverse Long-Term Outcomes in Patients with AKI.

J Am Soc Nephrol 2015 Jul 22;26(7):1747-54. Epub 2014 Dec 22.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania

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http://dx.doi.org/10.1681/ASN.2014060556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483589PMC
July 2015

An integrated approach for cardiorenal management.

Blood Purif 2014 31;37 Suppl 2. Epub 2014 Jul 31.

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http://dx.doi.org/10.1159/000361070DOI Listing
May 2015

Biomarkers in cardiorenal syndrome.

Blood Purif 2014 31;37 Suppl 2:14-9. Epub 2014 Jul 31.

Department of Critical Care, Western Sussex Hospitals Foundation Trust, Worthing, UK.

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http://dx.doi.org/10.1159/000361060DOI Listing
May 2015

Safety and dose-finding study of activated protein C (drotrecogin alfa activated) as an anticoagulant in end-stage renal disease patients treated with hemodialysis.

Blood Purif 2014 26;37(3):243-8. Epub 2014 Jun 26.

Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, D.C., USA.

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http://dx.doi.org/10.1159/000362154DOI Listing
March 2015

Thiamin deficiency in people with obesity.

Adv Nutr 2015 Mar 13;6(2):147-53. Epub 2015 Mar 13.

Department of Medicine, Veterans Affairs Medical Center, Washington, DC; Department of Medicine, George Washington University, Washington, DC;

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http://dx.doi.org/10.3945/an.114.007526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352173PMC
March 2015

Renal angina: concept and development of pretest probability assessment in acute kidney injury.

Crit Care 2015 Feb 27;19:93. Epub 2015 Feb 27.

Department of Nephrology, Dialysis & Transplantation, International Renal Research Institute, San Bortolo Hospital, Via Bertesina, Vicenza, 36100, Italy.

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http://dx.doi.org/10.1186/s13054-015-0779-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344798PMC
February 2015

Biomarkers of renal function, which and when?

Clin Chim Acta 2015 Jan 3;438:350-7. Epub 2014 Sep 3.

Division of Nephrology, Department of Medicine, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2014.08.039DOI Listing
January 2015

Introduction: sepsis-associated AKI.

Authors:
Lakhmir S Chawla

Semin Nephrol 2015 Jan;35(1)

Department of Medicine Veterans Affairs Medical Center Washington, DC.

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http://dx.doi.org/10.1016/j.semnephrol.2015.01.001DOI Listing
January 2015

Combining functional and tubular damage biomarkers improves diagnostic precision for acute kidney injury after cardiac surgery.

J Am Coll Cardiol 2014 Dec;64(25):2753-62

Center for Acute Care Nephrology, Cincinnati Children's Hospital and Medical Center, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1016/j.jacc.2014.09.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310455PMC
December 2014

Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers.

Nephrol Dial Transplant 2014 Nov 18;29(11):2054-61. Epub 2014 Sep 18.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1093/ndt/gfu292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209880PMC
November 2014

Derivation of urine output thresholds that identify a very high risk of AKI in patients with septic shock.

Clin J Am Soc Nephrol 2014 Jul 1;9(7):1168-74. Epub 2014 May 1.

Division of Nephrology and Hypertension and Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; and.

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http://dx.doi.org/10.2215/CJN.09360913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078959PMC
July 2014

Acute kidney injury and chronic kidney disease as interconnected syndromes.

N Engl J Med 2014 Jul;371(1):58-66

From the Department of Medicine, Division of Intensive Care Medicine, and the Division of Nephrology, Washington, DC, Veterans Affairs Medical Center (L.S.C.), and the Department of Anesthesiology and Critical Care Medicine (L.S.C.) and Department of Medicine, Division of Renal Diseases and Hypertension (L.S.C., P.L.K.), George Washington University Medical Center - both in Washington, DC; and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD (P.W.E., R.A.S., P.L.K.).

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http://vet.sagepub.com/content/52/3/441.full.pdf
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http://dx.doi.org/10.1056/NEJMra1214243DOI Listing
July 2014

Acute kidney injury: still deadly 10 years later.

Am J Respir Crit Care Med 2014 May;189(9):1016-7

1 The Center for Critical Care Nephrology University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center Pittsburgh, Pennsylvania and.

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http://dx.doi.org/10.1164/rccm.201403-0560EDDOI Listing
May 2014

The furosemide stress test to predict renal function after continuous renal replacement therapy. Authors' response.

Authors:
Lakhmir S Chawla

Crit Care 2014 May 14;18(3):429. Epub 2014 May 14.

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May 2014

Fluid management in adults and children: core curriculum 2014.

Am J Kidney Dis 2014 Apr 12;63(4):700-12. Epub 2013 Dec 12.

Division of Anesthesiology, George Washington Medical Center, Washington, DC; Division of Critical Care, George Washington Medical Center, Washington, DC. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2013.10.044DOI Listing
April 2014

Proposal for a functional classification system of heart failure in patients with end-stage renal disease: proceedings of the acute dialysis quality initiative (ADQI) XI workgroup.

J Am Coll Cardiol 2014 Apr 12;63(13):1246-1252. Epub 2014 Feb 12.

Department of Nephrology, Dialysis, and Transplantation, International Renal Research Institute, San Bortolo Hospital, Vicenza, Italy.

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http://dx.doi.org/10.1016/j.jacc.2014.01.020DOI Listing
April 2014

Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children.

Clin J Am Soc Nephrol 2014 Apr 27;9(4):654-62. Epub 2014 Mar 27.

Center for Acute Care Nephrology,, Divisions of ‡Critical Care and, §Biostatistics and Epidemiology, and, ¶The Heart Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;, †Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, ‖Division of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC.

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http://dx.doi.org/10.2215/CJN.09720913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974366PMC
April 2014

Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children.

Kidney Int 2014 Mar 18;85(3):659-67. Epub 2013 Sep 18.

1] Center for Acute Care Nephrology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA [2] The Heart Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1038/ki.2013.349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659420PMC
March 2014

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Kidney Int 2014 Mar 9;85(3):513-21. Epub 2013 Oct 9.

Division of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1038/ki.2013.374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198530PMC
March 2014

Association between AKI and long-term renal and cardiovascular outcomes in United States veterans.

Clin J Am Soc Nephrol 2014 Mar 5;9(3):448-56. Epub 2013 Dec 5.

Research and Medical Service, Veterans Affairs Medical Center, Washington, DC;, †Division of Renal Diseases and Hypertension, Department of Medicine, and, ‡Department of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC;, §Departments of Psychiatry and Surgery, Georgetown University School of Medicine, Washington, DC;, ‖Department of Anesthesiology, Duke University Medical Center and Veterans Affairs Medical Center, Durham, North Carolina, ¶National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.2215/CJN.02440213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944753PMC
March 2014

Evaluation of 32 urine biomarkers to predict the progression of acute kidney injury after cardiac surgery.

Kidney Int 2014 Feb 4;85(2):431-8. Epub 2013 Sep 4.

1] Department of Anesthesiology, Durham VA Medical Center, Durham, North Carolina, USA [2] Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1038/ki.2013.333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880389PMC
February 2014

Use of biomarkers to assess prognosis and guide management of patients with acute kidney injury.

Contrib Nephrol 2013 13;182:45-64. Epub 2013 May 13.

Department of Nephrology Dialysis & Transplantation, San Bortolo Hospital, Vicenza, Italy.

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http://dx.doi.org/10.1159/000349965DOI Listing
January 2014

Cardiorenal syndrome type 4: insights on clinical presentation and pathophysiology from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI).

Contrib Nephrol 2013 13;182:158-73. Epub 2013 May 13.

Department of Medicine, College of Medicine, University of Tennessee, Chattanooga, TN 37408, USA.

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http://dx.doi.org/10.1159/000349972DOI Listing
January 2014

Association of elevated urinary concentration of renin-angiotensin system components and severe AKI.

Clin J Am Soc Nephrol 2013 Dec 5;8(12):2043-52. Epub 2013 Sep 5.

Medical University of South Carolina, Charleston, South Carolina;, †University of Tennessee College of Medicine in Chattanooga, Chattanooga, Tennessee;, ‡George Washington University, Washington, DC;, §Duke University, Durham, North Carolina;, ‖Durham Veterans Affairs Medical Center, Durham, North Carolina, ¶Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina.

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http://dx.doi.org/10.2215/CJN.03510413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848399PMC
December 2013

Hydroxyethyl starch for fluid resuscitation in critically ill patients.

Can J Anaesth 2013 Jul 20;60(7):709-13. Epub 2013 Apr 20.

Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1.12 Walter C. Mackenzie Centre, 8440-122 ST NW, Edmonton, AB, T6G 2B7, Canada.

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http://dx.doi.org/10.1007/s12630-013-9936-4DOI Listing
July 2013

KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury.

Am J Kidney Dis 2013 May 15;61(5):649-72. Epub 2013 Mar 15.

Renal Section, VA Pittsburgh Healthcare System, Pittsburgh, PA 14240, USA.

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http://dx.doi.org/10.1053/j.ajkd.2013.02.349DOI Listing
May 2013

Acute kidney injury: Kidney attack must be prevented.

Nat Rev Nephrol 2013 Apr 12;9(4):198-9. Epub 2013 Feb 12.

Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy.

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http://dx.doi.org/10.1038/nrneph.2013.19DOI Listing
April 2013

AKI transition of care: a potential opportunity to detect and prevent CKD.

Clin J Am Soc Nephrol 2013 Mar;8(3):476-83

Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.2215/CJN.12101112DOI Listing
March 2013

Urinary angiotensinogen and risk of severe AKI.

Clin J Am Soc Nephrol 2013 Feb 8;8(2):184-93. Epub 2012 Nov 8.

Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.2215/CJN.06280612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562861PMC
February 2013

Novel biomarkers of AKI: the challenges of progress 'Amid the noise and the haste'.

Nephrol Dial Transplant 2013 Feb;28(2):235-8

Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G2B.

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http://dx.doi.org/10.1093/ndt/gfs595DOI Listing
February 2013

Hemodynamic monitoring in the critical care environment.

Adv Chronic Kidney Dis 2013 Jan;20(1):21-9

Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington DC, USA.

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http://dx.doi.org/10.1053/j.ackd.2012.10.006DOI Listing
January 2013

Disentanglement of the acute kidney injury syndrome.

Authors:
Lakhmir S Chawla

Curr Opin Crit Care 2012 Dec;18(6):579-84

Department of Anesthesiology and Critical Care Medicine and Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University Medical Center, Washington DC 20037, USA.

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http://dx.doi.org/10.1097/MCC.0b013e328358e59cDOI Listing
December 2012

Roundtable discussion: status asthmaticus in a patient with an anterior mediastinal mass.

Semin Cardiothorac Vasc Anesth 2012 Dec 29;16(4):243-9. Epub 2012 Oct 29.

University of Florida, Gainesville, FL 32810-0254, USA.

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http://dx.doi.org/10.1177/1089253212464277DOI Listing
December 2012

Predicting progression to chronic kidney disease after recovery from acute kidney injury.

Curr Opin Nephrol Hypertens 2012 Nov;21(6):628-34

Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1097/MNH.0b013e3283588f24DOI Listing
November 2012

Acute kidney injury and chronic kidney disease: an integrated clinical syndrome.

Kidney Int 2012 Sep 6;82(5):516-24. Epub 2012 Jun 6.

Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1038/ki.2012.208DOI Listing
September 2012

Off-pump versus on-pump coronary artery bypass grafting outcomes stratified by preoperative renal function.

J Am Soc Nephrol 2012 Aug 17;23(8):1389-97. Epub 2012 May 17.

Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, 900 23rd Street NW, RILF, Washington, DC 20037, USA.

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http://dx.doi.org/10.1681/ASN.2012020122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402290PMC
August 2012

Permissive hypofiltration.

Crit Care 2012 Jul 26;16(4):317. Epub 2012 Jul 26.

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http://dx.doi.org/10.1186/cc11253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580674PMC
July 2012