Publications by authors named "Laishram Jaichand Singh"

3 Publications

  • Page 1 of 1

Clinico-Epidemiologic Patterns of Laryngeal Cancer: 5-year Results from a Regional Cancer Centre in Northeastern India.

Asian Pac J Cancer Prev 2016 ;17(5):2439-43

Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India E-mail :

Purpose: To determine the risk factors, clinical symptoms and patterns of spread in laryngeal cancer.

Materials And Methods: A cross sectional study was carried out in the Regional Cancer Centre, Imphal, Manipur, India. One hundred and sixteen patients with laryngeal cancer were retrospectively reviewed for epidemiological data and descriptive statistics were reported for various variables.

Results: Median age at presentation was 65 years and 32.8% were undernourished at presentation. The male to female ratio was 5.4:1. Heavy smoking and tobacco chewing was associated in 91.4% and 33.6% of patients respectively. Tracheostomy was required in 21.5% leading to diagnosis of laryngeal cancer. Almost all were squamous cell carcinoma with neuroendocrine and verrucous carcinoma accounting for less than 2%. Supraglottic, glottic and trans-glottic tumors were 56.9%, 36.3% and 6.9% respectively. Nodal metastases were seen in 81.8% of supraglottic cancers and 31.6% of glottic cancers with supraglottic involvement. Level II neck nodes were the commonest site followed by level III. Distant metastases (only liver) were apparent in 1.7% at presentation. Including these liver metastases, unresectable cases were limited to 6% of the patients.

Conclusions: Tobacco use is implicated in almost all of the cases and the sex ratio has also decreased due to increased female smokers. The supraglottis remains the commonest site and incidence of nodal metastases is higher than in other countries. There is also a higher requirement for tracheostomy at presentation in this region.
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January 2017

Acute myeloid leukemia following chemotherapy for gestational trophoblatic neoplasia.

J Obstet Gynaecol India 2014 Dec 13;64(Suppl 1):55-6. Epub 2014 Jun 13.

Department of Radiotherapy, Regional Cancer Center (RCC), Regional Institute of Medical Sciences, Imphal, 795004 India.

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December 2014

Intra-abdominal desmoplastic small cell tumour--a case report.

Indian J Pathol Microbiol 2003 Jul;46(3):448-9

Department of Pathology, Regional Institute of Medical Sciences, Babina Diagnostic Centre and CCMC and Research Centre, Imphal, Manipur.

Intra-abdominal desmoplastic small cell tumour is a rare malignant neoplasm of childhood. We report a case of this uncommon tumour in a 14-year-old boy. The tumour originated from transverse mesocolon. The case is notable because there was no pain and ascites on presentation and there was transmural infiltration of the transverse colon.
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July 2003