Laetitia Malphettes

Laetitia Malphettes

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Laetitia Malphettes

Laetitia Malphettes

Publications by authors named "Laetitia Malphettes"

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13Publications

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Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process.

Metab Eng 2019 01 15;51:9-19. Epub 2018 Sep 15.

Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 223, 2800 Kgs, Lyngby, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176183022
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http://dx.doi.org/10.1016/j.ymben.2018.09.009DOI Listing
January 2019

Segmented linear modeling of CHO fed-batch culture and its application to large scale production.

Biotechnol Bioeng 2017 04 21;114(4):785-797. Epub 2016 Nov 21.

Biochemical Engineering Institute, Saarland University, Campus A1.5, D-66123 Saarbrücken, Germany.

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http://dx.doi.org/10.1002/bit.26214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324675PMC
April 2017

Macroscopic modeling of mammalian cell growth and metabolism.

Appl Microbiol Biotechnol 2015 Sep 22;99(17):7009-24. Epub 2015 Jul 22.

Biochemical Engineering Institute, Saarland University, Campus A1.5, D-66123, Saarbruecken, Germany.

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http://dx.doi.org/10.1007/s00253-015-6743-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536272PMC
September 2015

Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells.

BMC Proc 2011 22;5 Suppl 8:P75. Epub 2011 Nov 22.

Cell Culture Process Development Group, Biological Process Development, UCB Pharma S.A., Braine L'Alleud, 1420, Belgium.

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http://dx.doi.org/10.1186/1753-6561-5-S8-P75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285007PMC
April 2015

Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process.

BMC Proc 2011 22;5 Suppl 8:P70. Epub 2011 Nov 22.

Cell Culture Process Development Group, Biological Process Development, UCB Pharma S.A, Braine-l'Alleud, 1420, Belgium.

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http://dx.doi.org/10.1186/1753-6561-5-S8-P70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284957PMC
April 2015

6-hydroxy-nicotine-inducible multilevel transgene control in mammalian cells.

Metab Eng 2006 Nov 22;8(6):543-53. Epub 2006 Jul 22.

Institute for Chemical and Bio-Engineering, ETH Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ymben.2006.07.001DOI Listing
November 2006

Impact of RNA interference on gene networks.

Metab Eng 2006 Nov 4;8(6):672-83. Epub 2006 Aug 4.

Institute for Chemical and Bio-Engineering, Swiss Federal Institute of Technology-ETH Zurich, CH-8093 Zurich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S10967176060006
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http://dx.doi.org/10.1016/j.ymben.2006.07.005DOI Listing
November 2006

Improved transgene expression fine-tuning in mammalian cells using a novel transcription-translation network.

J Biotechnol 2006 Aug 20;124(4):732-46. Epub 2006 Feb 20.

Institute for Chemical and Bio-Engineering (ICB), Swiss Federal Institute of Technology-ETH Zurich, Wolfgang-Pauli-Strasse 10, ETH Hoenggerberg, HCI F115, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jbiotec.2006.01.003DOI Listing
August 2006

Quorum-sensing-based toolbox for regulatable transgene and siRNA expression in mammalian cells.

Biotechnol Prog 2005 Jan-Feb;21(1):178-85

Institute of Chemical- and Bio-Engineering, Swiss Federal Institute of Technology, ETH Hoenggerberg HCI F115, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1021/bp0498995DOI Listing
July 2005

A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1.

Nucleic Acids Res 2005 Jul 7;33(12):e107. Epub 2005 Jul 7.

Institute for Chemical and Bio-Engineering (ICB), Swiss Federal Institute of Technology, ETH Hoenggerberg, HCI F115 Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland.

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https://nar.oxfordjournals.org/content/33/12/e107.full-text-
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gni107
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http://dx.doi.org/10.1093/nar/gni107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174900PMC
July 2005

Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells using polymerase II-dependent promoter derivatives.

Biotechnol Bioeng 2004 Nov;88(4):417-25

Institute of Biotechnology, Swiss Federal Institute of Technology, ETH Hönggerberg, HPT D74, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1002/bit.20230DOI Listing
November 2004