Publications by authors named "Kyung-Sang Yu"

243Publications

An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans.

Authors:
Anhye Kim Stephen R Dueker Jun Gi Hwang Jangsoo Yoon Sang-Won Lee Hye Suk Lee Byung-Yong Yu Kyung-Sang Yu Howard Lee

Clin Transl Sci 2020 Jul 23. Epub 2020 Jul 23.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.

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July 2020

Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes.

Authors:
Suhrin Lee SeungHwan Lee In-Jin Jang Kyung-Sang Yu Su-Jin Rhee

Transl Clin Pharmacol 2020 Dec 18;28(4):199-207. Epub 2020 Dec 18.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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December 2020

Evaluation of the pharmacokinetics and food effects of a novel formulation tamsulosin 0.4 mg capsule compared with a 0.2 mg capsule in healthy male volunteers.

Authors:
Mu Seong Ban Yu Kyong Kim Byungwook Kim Jina Jung Yong-Il Kim Jaeseong Oh Kyung-Sang Yu

Transl Clin Pharmacol 2020 Dec 24;28(4):181-188. Epub 2020 Nov 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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December 2020

The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects.

Authors:
Soyoung Lee Andrew HyoungJin Kim Sumin Yoon Jieon Lee Yujin Lee Sang Chun Ji Seo Hyun Yoon SeungHwan Lee Kyung-Sang Yu In-Jin Jang Joo-Youn Cho

Drug Metab Pharmacokinet 2020 Nov 12;36:100368. Epub 2020 Nov 12.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2020

Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects.

Authors:
Soyoung Lee Yujin Lee Andrew HyoungJin Kim Sumin Yoon Jieon Lee Sang Chun Ji Seo Hyun Yoon SeungHwan Lee Kyung-Sang Yu In-Jin Jang Joo-Youn Cho

Drug Metab Pharmacokinet 2020 Dec 3;36:100374. Epub 2020 Dec 3.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2020

Tolerability of lacosamide rapid dose titration: A randomized, multicenter, prospective, open-label study.

Authors:
Yong-Won Shin Jangsup Moon Yong Won Cho Dong Wook Kim Sang Bin Hong Do-Yong Kim Hyeyeon Chang Seo Hyun Yoon Kyung-Sang Yu In-Jin Jang Soon-Tae Lee Keun-Hwa Jung Kyung-Il Park Ki-Young Jung Manho Kim Kon Chu SeungHwan Lee Sang Kun Lee

Epilepsy Behav 2020 Dec 17:107663. Epub 2020 Dec 17.

Department of Neurology, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address:

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December 2020

Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy.

Authors:
Seon-Jae Ahn Tae-Joon Kim Kwang Su Cha Jin-Sun Jun Jung-Ick Byun Yong-Won Shin Jun-Sang Sunwoo SeungHwan Lee Kyung-Sang Yu In-Jin Jang Kon Chu Sang Kun Lee Ki-Young Jung

Epilepsy Behav 2020 Dec 14:107514. Epub 2020 Dec 14.

Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2020

Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects.

Authors:
Hyounggyoon Yoo Yun Kim In-Jin Jang Kyung-Sang Yu SeungHwan Lee

Drug Des Devel Ther 2020 24;14:5179-5187. Epub 2020 Nov 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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November 2020

A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators.

Authors:
Hyounggyoon Yoo Sang Chun Ji Joo-Youn Cho Sang-Heon Kim Jihoon G Yoon Min Goo Lee Kyung-Sang Yu In-Jin Jang Jaeseong Oh

Pharmacogenet Genomics 2020 Nov 6. Epub 2020 Nov 6.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital.

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November 2020

Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects.

Authors:
Jung Sunwoo Sang Chun Ji Jaeseong Oh Mu Seong Ban Ji Yeon Nam Bongtae Kim Geun Seog Song Kyung-Sang Yu In-Jin Jang SeungHwan Lee

Aliment Pharmacol Ther 2020 12 1;52(11-12):1640-1647. Epub 2020 Nov 1.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects.

Authors:
Inyoung Hwang Yun Kim Hyounggyoon Yoo In-Jin Jang Kyung-Sang Yu SeungHwan Lee

Drug Des Devel Ther 2020 23;14:4493-4502. Epub 2020 Oct 23.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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October 2020

Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities.

Authors:
Jun Gi Hwang Inseung Jeon Sun Ae Park Areum Lee Kyung-Sang Yu In-Jin Jang SeungHwan Lee

Aliment Pharmacol Ther 2020 12 27;52(11-12):1648-1657. Epub 2020 Oct 27.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-blind, Placebo-controlled Study in Healthy Male Subjects.

Authors:
Eunwoo Kim Inyoung Hwang SeungHwan Lee Jaeseong Oh Hyewon Chung Myungwon Jin Soon Ha Kim Kyung-Sang Yu

Clin Ther 2020 Oct 24;42(10):1946-1954.e2. Epub 2020 Sep 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address:

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October 2020

Optimization and validation of a fluorogenic dipeptidyl peptidase 4 enzymatic assay in human plasma.

Authors:
Hyunyee Yoon Su Hee Cho Yu Rim Seo Kyung-Sang Yu Sung Sup Park Moon Jung Song

Anal Biochem 2021 01 12;612:113952. Epub 2020 Sep 12.

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. Electronic address:

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January 2021

The Impact of COVID-19 on the Conduct of Clinical Trials for Medical Products in Korea.

Authors:
JuYeun Jeon Hyeikyoung Kim Kyung Sang Yu

J Korean Med Sci 2020 Sep 14;35(36):e329. Epub 2020 Sep 14.

Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

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September 2020

Comparison of the Pharmacokinetics of a Fixed-Dose Combination of Rosuvastatin/Metformin Sustained-Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects.

Authors:
Ki Young Huh Eunwoo Kim Heechan Lee Inseung Jeon Hearan Suh Jongsun Lee Yunhee Lee Kyung-Sang Yu SeungHwan Lee

Clin Pharmacol Drug Dev 2020 Jun 24. Epub 2020 Jun 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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June 2020

Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets.

Authors:
Jun Gi Hwang Kyung-Sang Yu SeungHwan Lee

Drug Des Devel Ther 2020 20;14:1953-1961. Epub 2020 May 20.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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May 2020

Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers.

Authors:
Sang Won Lee Jaeseong Oh Andrew HyoungJin Kim Sang Chun Ji Sang-In Park Seo Hyun Yoon Jae-Young Chung Kyung-Sang Yu In-Jin Jang SeungHwan Lee

Pharmacogenomics J 2020 12 27;20(6):792-800. Epub 2020 May 27.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

Usefulness of saliva for perampanel therapeutic drug monitoring.

Authors:
Do-Yong Kim Jangsup Moon Yong-Won Shin Soon-Tae Lee Keun-Hwa Jung Kyung-Il Park Ki-Young Jung Manho Kim SeungHwan Lee Kyung-Sang Yu In-Jin Jang KaHeon Song Kon Chu Sangkun Lee

Epilepsia 2020 06 7;61(6):1120-1128. Epub 2020 May 7.

Department of Neurology, Seoul National University Hospital, Seoul, South Korea.

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June 2020

An Assessment of Pharmacokinetic Interaction Between Lobeglitazone and Sitagliptin After Multiple Oral Administrations in Healthy Men.

Authors:
Seol Ju Moon Kyung-Sang Yu Min-Gul Kim

Clin Ther 2020 06 30;42(6):1047-1057. Epub 2020 Apr 30.

Center for Clinical Pharmacology and Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University, Jeonju, Republic of Korea; Department of Pharmacology, School of Medicine, Jeonbuk National University, Jeonju, Republic of Korea. Electronic address:

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June 2020