Publications by authors named "Kyung-Sang Yu"

243Publications

An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans.

Clin Transl Sci 2020 Jul 23. Epub 2020 Jul 23.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.

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July 2020

Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes.

Transl Clin Pharmacol 2020 Dec 18;28(4):199-207. Epub 2020 Dec 18.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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December 2020

Evaluation of the pharmacokinetics and food effects of a novel formulation tamsulosin 0.4 mg capsule compared with a 0.2 mg capsule in healthy male volunteers.

Transl Clin Pharmacol 2020 Dec 24;28(4):181-188. Epub 2020 Nov 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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December 2020

The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects.

Drug Metab Pharmacokinet 2020 Nov 12;36:100368. Epub 2020 Nov 12.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2020

Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects.

Drug Metab Pharmacokinet 2020 Dec 3;36:100374. Epub 2020 Dec 3.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2020

Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy.

Epilepsy Behav 2020 Dec 14:107514. Epub 2020 Dec 14.

Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2020

Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects.

Drug Des Devel Ther 2020 24;14:5179-5187. Epub 2020 Nov 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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November 2020

A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators.

Pharmacogenet Genomics 2020 Nov 6. Epub 2020 Nov 6.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital.

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November 2020

Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects.

Aliment Pharmacol Ther 2020 12 1;52(11-12):1640-1647. Epub 2020 Nov 1.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects.

Drug Des Devel Ther 2020 23;14:4493-4502. Epub 2020 Oct 23.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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October 2020

Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities.

Aliment Pharmacol Ther 2020 12 27;52(11-12):1648-1657. Epub 2020 Oct 27.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-blind, Placebo-controlled Study in Healthy Male Subjects.

Clin Ther 2020 Oct 24;42(10):1946-1954.e2. Epub 2020 Sep 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address:

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October 2020

Optimization and validation of a fluorogenic dipeptidyl peptidase 4 enzymatic assay in human plasma.

Anal Biochem 2021 01 12;612:113952. Epub 2020 Sep 12.

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. Electronic address:

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January 2021

The Impact of COVID-19 on the Conduct of Clinical Trials for Medical Products in Korea.

J Korean Med Sci 2020 Sep 14;35(36):e329. Epub 2020 Sep 14.

Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

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September 2020

Comparison of the Pharmacokinetics of a Fixed-Dose Combination of Rosuvastatin/Metformin Sustained-Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects.

Clin Pharmacol Drug Dev 2020 Jun 24. Epub 2020 Jun 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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June 2020

Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets.

Drug Des Devel Ther 2020 20;14:1953-1961. Epub 2020 May 20.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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May 2020

Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers.

Pharmacogenomics J 2020 12 27;20(6):792-800. Epub 2020 May 27.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.

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December 2020

An Assessment of Pharmacokinetic Interaction Between Lobeglitazone and Sitagliptin After Multiple Oral Administrations in Healthy Men.

Clin Ther 2020 06 30;42(6):1047-1057. Epub 2020 Apr 30.

Center for Clinical Pharmacology and Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University, Jeonju, Republic of Korea; Department of Pharmacology, School of Medicine, Jeonbuk National University, Jeonju, Republic of Korea. Electronic address:

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June 2020