Publications by authors named "Kyung-Rok Yu"

31Publications

Impact of mesenchymal stem cell senescence on inflammaging.

BMB Rep 2020 Feb;53(2):65-73

Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

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February 2020

CRISPR/Cas9 gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs.

Blood 2019 06 19;133(23):2542-2545. Epub 2019 Apr 19.

Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.

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June 2019

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.

Cell 2018 05 31;173(6):1439-1453.e19. Epub 2018 May 31.

Center for Cellular Immunotherapies, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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May 2018

GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging.

Exp Mol Med 2018 05 14;50(5):1-12. Epub 2018 May 14.

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.

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May 2018

Direct Conversion of Human Umbilical Cord Blood into Induced Neural Stem Cells with SOX2 and HMGA2.

Int J Stem Cells 2017 Nov;10(2):227-234

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, Korea.

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November 2017

Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles.

Hum Gene Ther 2016 10 2;27(10):729-740. Epub 2016 Aug 2.

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda, Maryland.

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October 2016

DNA methyltransferase inhibition accelerates the immunomodulation and migration of human mesenchymal stem cells.

Sci Rep 2015 Jan 26;5:8020. Epub 2015 Jan 26.

1] Research Institute for Veterinary Medicine, College of Veterinary Medicine, Seoul National University, Seoul 151-742, South Korea [2] Institute for Stem Cell and Regenerative Medicine in KangstemBiotech, Biotechnology Incubating Center, Seoul National University, Seoul 151-742, South Korea.

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January 2015

Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b.

Cell Rep 2015 Jan 15;10(3):441-452. Epub 2015 Jan 15.

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea; The Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. Electronic address:

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January 2015

Human umbilical cord blood mesenchymal stem cell-derived PGE2 and TGF-β1 alleviate atopic dermatitis by reducing mast cell degranulation.

Stem Cells 2015 Apr;33(4):1254-66

Adult Stem Cell Research Center, College of Veterinary Medicine#406 Biotechnology Incubating Center, Seoul National University, Seoul, South Korea; Institute for Stem Cell and Regenerative Medicine in Kangstem Biotech, #406 Biotechnology Incubating Center, Seoul National University, Seoul, South Korea.

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April 2015

miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18.

Age (Dordr) 2014 4;36(6):9724. Epub 2014 Dec 4.

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, 151-742, Republic of Korea.

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June 2015

Excessive microglial activation aggravates olfactory dysfunction by impeding the survival of newborn neurons in the olfactory bulb of Niemann-Pick disease type C1 mice.

Biochim Biophys Acta 2014 Nov 15;1842(11):2193-203. Epub 2014 Aug 15.

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul 151-742, South Korea; Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 151-742, South Korea. Electronic address:

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November 2014

A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging.

PLoS One 2014 4;9(8):e102426. Epub 2014 Aug 4.

Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, South Korea; Research Institute for Veterinary Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea.

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November 2015

Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule.

Sci Rep 2014 Jul 3;4:5546. Epub 2014 Jul 3.

1] Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea [2] BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University.

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July 2014