Kyung-Hyun Park-Min

Kyung-Hyun Park-Min

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Kyung-Hyun Park-Min

Kyung-Hyun Park-Min

Publications by authors named "Kyung-Hyun Park-Min"

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Insights into rheumatic diseases from next-generation sequencing.

Nat Rev Rheumatol 2019 Apr 18. Epub 2019 Apr 18.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, USA.

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http://dx.doi.org/10.1038/s41584-019-0217-7DOI Listing
April 2019

Mechanisms involved in normal and pathological osteoclastogenesis.

Cell Mol Life Sci 2018 07 18;75(14):2519-2528. Epub 2018 Apr 18.

Arthritis and Tissue Degeneration Program, David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, 535 East 70th Street, New York, 10021, NY, USA.

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http://dx.doi.org/10.1007/s00018-018-2817-9DOI Listing
July 2018

Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation.

Nat Immunol 2017 Oct 21;18(10):1104-1116. Epub 2017 Aug 21.

Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605457PMC
October 2017

Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF.

Immunity 2017 08;47(2):235-250.e4

Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, NY 10021, USA; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568089PMC
August 2017

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα.

J Clin Invest 2017 Jun 22;127(7):2555-2568. Epub 2017 May 22.

Arthritis and Tissue Degeneration Program, David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI89935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490751PMC
June 2017

Epigenetic regulation of bone cells.

Connect Tissue Res 2017 01 14;58(1):76-89. Epub 2016 Apr 14.

a Arthritis and Tissue Degeneration Program and David C. Rosensweig Center for Genomics Research, Hospital for Special Surgery , New York , NY , USA.

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https://www.tandfonline.com/doi/full/10.1080/03008207.2016.1
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http://dx.doi.org/10.1080/03008207.2016.1177037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498111PMC
January 2017

Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages.

Sci Rep 2016 08 25;6:31959. Epub 2016 Aug 25.

Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, 1300 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/srep31959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997257PMC
August 2016

Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8.

J Immunol 2016 06 29;196(11):4452-4456. Epub 2016 Apr 29.

Arthritis and Tissue Degeneration Program David Z. Rosensweig Genomics Research Center Hospital for Special Surgery.

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http://dx.doi.org/10.4049/jimmunol.1501466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875854PMC
June 2016

Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression.

J Cell Physiol 2016 Feb;231(2):449-458

Arthritis and Tissue Degeneration Program, David Z. Rosensweig Center for Genomic Research, Hospital for Special Surgery, New York, NY 10021 USA.

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http://dx.doi.org/10.1002/jcp.25091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779648PMC
February 2016

Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass.

Proc Natl Acad Sci U S A 2015 Dec 7;112(51):15654-9. Epub 2015 Dec 7.

Department of Orthopaedic Surgery, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO 63110;

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http://dx.doi.org/10.1073/pnas.1511285112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697402PMC
December 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation.

Nat Commun 2014 Nov 13;5:5418. Epub 2014 Nov 13.

1] Arthritis and Tissue Degeneration Program and David C. Rosensweig Center for Genomics Research, Hospital for Special Surgery, New York, New York 10021, USA [2] Department of Medicine, Weill Cornell Medical College, New York, New York 10021, USA [3] Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncomms6418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249944PMC
November 2014

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.

J Clin Invest 2013 Feb 25;123(2):928-32. Epub 2013 Jan 25.

Arthritis and Tissue Degeneration Program, Autoimmunity and Inflammation Program, Hospital for Special Surgery, Weill Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI66168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561822PMC
February 2013

ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.

J Immunol 2012 Apr 24;188(7):3447-57. Epub 2012 Feb 24.

Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, NY 10021, USA.

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http://dx.doi.org/10.4049/jimmunol.1102211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311708PMC
April 2012

Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8.

Ann N Y Acad Sci 2011 Nov;1237:88-94

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2011.06217.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263822PMC
November 2011

Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages.

Nat Immunol 2011 May 22;12(7):607-15. Epub 2011 May 22.

Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.2043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258532PMC
May 2011

Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors.

J Immunol 2009 Dec 4;183(11):7223-33. Epub 2009 Nov 4.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, NY 10021, USA.

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http://dx.doi.org/10.4049/jimmunol.0900072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783334PMC
December 2009

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

Hum Immunol 2009 Apr 7;70(4):211-7. Epub 2009 Feb 7.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1016/j.humimm.2009.01.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811352PMC
April 2009

Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2.

J Leukoc Biol 2008 Nov 4;84(5):1353-60. Epub 2008 Aug 4.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1189/jlb.0107040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567899PMC
November 2008

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.

Nat Immunol 2008 Apr 16;9(4):378-87. Epub 2008 Mar 16.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ni1576DOI Listing
April 2008

'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.

Nat Immunol 2008 Feb 16;9(2):186-93. Epub 2007 Dec 16.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ni1548DOI Listing
February 2008

Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages.

Hum Immunol 2007 Mar 8;68(3):156-64. Epub 2007 Jan 8.

Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.humimm.2006.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736914PMC
March 2007

FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.

Immunity 2007 Jan;26(1):67-78

Graduate Program in Immunology and Microbial Pathogenesis, Weill Medical College and Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130600566
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http://dx.doi.org/10.1016/j.immuni.2006.11.010DOI Listing
January 2007

Regulation of macrophage phenotype by long-term exposure to IL-10.

Immunobiology 2005 ;210(2-4):77-86

Graduate Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.imbio.2005.05.002DOI Listing
October 2005

Kinetics of IL-10-induced gene expression in human macrophages.

Immunobiology 2005 ;210(2-4):87-95

Arthritis and Tissue Degeneration Program, Department of Medicine, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.imbio.2005.05.003DOI Listing
October 2005

IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1.

J Immunol 2005 Sep;175(6):3637-47

Arthritis and Tissue Degeneration Program, Department of Medicine, Hospital for Special Surgery, Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.4049/jimmunol.175.6.3637DOI Listing
September 2005