Publications by authors named "Kyung Yong Lee"

17Publications

The pan-cancer landscape of prognostic germline variants in 10,582 patients.

Genome Med 2020 02 17;12(1):15. Epub 2020 Feb 17.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1240 Pinn Hall, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1186/s13073-020-0718-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027124PMC
February 2020

The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers.

Mol Cell 2018 12 8;72(5):823-835.e5. Epub 2018 Nov 8.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294304PMC
December 2018

ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.

Mol Cell 2017 Oct 21;68(1):61-75.e5. Epub 2017 Sep 21.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22901, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743198PMC
October 2017

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.

Nat Commun 2015 Jul 28;6:7744. Epub 2015 Jul 28.

Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Jordan Hall, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908 USA.

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http://dx.doi.org/10.1038/ncomms8744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525285PMC
July 2015

Initiation of replication in Xenopus egg extracts at a spatially defined origin.

Cell Cycle 2015 Aug 19;14(15):2391. Epub 2015 Jun 19.

a Department of Biochemistry and Molecular Genetics ; University of Virginia ; Charlottesville , VA USA.

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http://dx.doi.org/10.1080/15384101.2015.1063306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612457PMC
August 2015

Dephosphorylation of Orc2 by protein phosphatase 1 promotes the binding of the origin recognition complex to chromatin.

Biochem Biophys Res Commun 2014 Jun 30;448(4):385-9. Epub 2014 Apr 30.

Department of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.04.109DOI Listing
June 2014

Protein phosphatase 1 dephosphorylates Orc2.

Biochem Biophys Res Commun 2014 May 13;447(3):437-40. Epub 2014 Apr 13.

Department of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.04.029DOI Listing
May 2014

ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks.

Genes Dev 2014 Apr 3;28(8):875-87. Epub 2014 Apr 3.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1101/gad.239194.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003279PMC
April 2014

Human Primpol1: a novel guardian of stalled replication forks.

EMBO Rep 2013 Dec 5;14(12):1032-3. Epub 2013 Nov 5.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2013.171
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http://dx.doi.org/10.1038/embor.2013.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981087PMC
December 2013

A bumblebee (Bombus ignitus) venom serine protease inhibitor that acts as a microbial serine protease inhibitor.

Comp Biochem Physiol B Biochem Mol Biol 2014 Jan 21;167:59-64. Epub 2013 Oct 21.

College of Natural Resources and Life Science, Dong-A University, Busan 604-714, Republic of Korea.

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http://dx.doi.org/10.1016/j.cbpb.2013.10.002DOI Listing
January 2014

The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.

Mol Cell Biol 2013 Apr 11;33(8):1632-44. Epub 2013 Feb 11.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1128/MCB.01503-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624244PMC
April 2013

Human umbilical cord blood-derived mesenchymal stem cells undergo cellular senescence in response to oxidative stress.

Stem Cells Dev 2012 Jul 23;21(11):1877-86. Epub 2011 Dec 23.

Department of Biological Sciences, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1089/scd.2011.0284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396141PMC
July 2012

TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells.

J Biol Chem 2011 Feb 13;286(7):5414-22. Epub 2010 Dec 13.

Cancer Experimental Resources Branch, National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-769, Korea.

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http://dx.doi.org/10.1074/jbc.M110.189704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037654PMC
February 2011

Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition.

J Biol Chem 2007 May 10;282(20):14882-90. Epub 2007 Feb 10.

Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1074/jbc.M609116200DOI Listing
May 2007

Dimeric configuration of SeqA protein bound to a pair of hemi-methylated GATC sequences.

Nucleic Acids Res 2005 14;33(5):1524-31. Epub 2005 Mar 14.

Institute of Molecular Biology and Genetics, Seoul National University Seoul 151-742, Republic of Korea.

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http://dx.doi.org/10.1093/nar/gki289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065253PMC
March 2005