Kyu-Won Kim

Kyu-Won Kim

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Kyu-Won Kim

Publications by authors named "Kyu-Won Kim"

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Genome-wide association study of vitamin E using genotyping by sequencing in sesame (Sesamum indicum).

Authors:
Qiang He Feifei Xu Myeong-Hyeon Min Sang-Ho Chu Kyu-Won Kim Yong-Jin Park

Genes Genomics 2019 09 13;41(9):1085-1093. Epub 2019 Jun 13.

Department of Plant Resources, College of Industrial Science, Kongju National University, Yesan, 32439, Korea.

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http://dx.doi.org/10.1007/s13258-019-00837-3DOI Listing
September 2019

Signatures of differential selection in chloroplast genome between japonica and indica.

Authors:
Lin Cheng Jungrye Nam Sang-Ho Chu Phitaktansakul Rungnapa Myeong-Hyeon Min Yuan Cao Ji-Min Yoo Jee-Su Kang Kyu-Won Kim Yong-Jin Park

Rice (N Y) 2019 Aug 14;12(1):65. Epub 2019 Aug 14.

Department of Plant Resources, College of Industrial Science, Kongju National University, Yesan, 32439, Republic of Korea.

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http://dx.doi.org/10.1186/s12284-019-0322-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692809PMC
August 2019

Colorimetric biosensor using dual-amplification of enzyme-free reaction through universal hybridization chain reaction system.

Authors:
Chae Rin Park Won Jong Rhee Kyu Won Kim Byeong Hee Hwang

Biotechnol Bioeng 2019 Jul 17;116(7):1567-1574. Epub 2019 Apr 17.

Department of Bioengineering and Nano-bioengineering, Incheon National University, Incheon, Korea.

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http://dx.doi.org/10.1002/bit.26978DOI Listing
July 2019

Evidence for selection events during domestication by extensive mitochondrial genome analysis between japonica and indica in cultivated rice.

Authors:
Lin Cheng Kyu-Won Kim Yong-Jin Park

Sci Rep 2019 Jul 26;9(1):10846. Epub 2019 Jul 26.

Department of Plant Resources, College of Industrial Science, Kongju National University, Yesan, 32439, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-019-47318-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659709PMC
July 2019

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.

Authors:
Ho Shin Kim Van-Hai Hoang Mannkyu Hong Kyung Chul Kim Jihyae Ann Cong-Truong Nguyen Ji Hae Seo Hoon Choi Jun Yong Kim Kyu-Won Kim Woong Sub Byun Sangkook Lee Seungbeom Lee Young-Ger Suh Jie Chen Hyun-Ju Park Tae-Min Cho Ji Young Kim Jae Hong Seo Jeewoo Lee

Bioorg Med Chem 2019 Apr 20;27(7):1370-1381. Epub 2019 Feb 20.

College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.02.040DOI Listing
April 2019

Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit.

Authors:
Yoon Kyung Choi Joon Ha Park Jung-A Yun Jong-Ho Cha Yonghee Kim Moo-Ho Won Kyu-Won Kim Kwon-Soo Ha Young-Guen Kwon Young-Myeong Kim

PLoS One 2018 28;13(8):e0202039. Epub 2018 Aug 28.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Kangwon-do, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202039PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112640PMC
February 2019

Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts.

Authors:
Sung-Jin Bae Min Wook Shin Taekwon Son Hye Shin Lee Ji Soo Chae Sejin Jeon Goo Taeg Oh Kyu-Won Kim

Exp Mol Med 2019 01 16;51(1). Epub 2019 Jan 16.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Korea.

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http://dx.doi.org/10.1038/s12276-018-0201-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353902PMC
January 2019

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release.

Authors:
Aloran Mazumder Jin-Young Lee Oualid Talhi Claudia Cerella Sébastien Chateauvieux Anthoula Gaigneaux Che Ry Hong Hyoung Jin Kang Youngjo Lee Kyu-Won Kim Dong-Wook Kim Hee-Young Shin Mario Dicato Khaldoun Bachari Artur M S Silva Barbora Orlikova-Boyer Marc Diederich

Cancer Lett 2018 12 8;438:197-218. Epub 2018 Sep 8.

Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08626, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.07.041DOI Listing
December 2018

A-kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide-induced liver injury.

Authors:
Hye Shin Lee Jinhyeok Choi Taekwon Son Eun Ji Lee Jeong-Gyun Kim Soo Hyung Ryu Danbi Lee Myoung Kuk Jang Eunsil Yu Young-Hwa Chung Irwin H Gelman Kyu-Won Kim

Oncol Lett 2018 Nov 4;16(5):5907-5915. Epub 2018 Sep 4.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

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http://www.spandidos-publications.com/10.3892/ol.2018.9396
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http://dx.doi.org/10.3892/ol.2018.9396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176350PMC
November 2018

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.

Authors:
Hongchan An Seungbeom Lee Jung Min Lee Dong Hyun Jo Joohwan Kim Yoo-Seong Jeong Mi Jeong Heo Chang Sik Cho Hoon Choi Ji Hae Seo Seyeon Hwang Jihye Lim Taewoo Kim Hyoung Oh Jun Jaehoon Sim Changjin Lim Joonseong Hur Jungmin Ahn Hyun Su Kim Seung-Yong Seo Younghwa Na Seok-Ho Kim Jeewoo Lee Jeeyeon Lee Suk-Jae Chung Young-Myeong Kim Kyu-Won Kim Sang Geon Kim Jeong Hun Kim Young-Ger Suh

J Med Chem 2018 10 9;61(20):9266-9286. Epub 2018 Oct 9.

College of Pharmacy , Seoul National University , Seoul 08826 , Republic of Korea.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00971DOI Listing
October 2018

A Genome-Wide Association Study Reveals Candidate Genes Related to Salt Tolerance in Rice () at the Germination Stage.

Authors:
Jie Yu Weiguo Zhao Wei Tong Qiang He Min-Young Yoon Feng-Peng Li Buung Choi Eun-Beom Heo Kyu-Won Kim Yong-Jin Park

Int J Mol Sci 2018 Oct 12;19(10). Epub 2018 Oct 12.

Department of Plant Resources, College of Industrial Sciences, Kongju National University, Yesan 32439, Korea.

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http://www.mdpi.com/1422-0067/19/10/3145
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http://dx.doi.org/10.3390/ijms19103145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213974PMC
October 2018

Effects of ischemic post-conditioning on neuronal VEGF regulation and microglial polarization in a rat model of focal cerebral ischemia.

Authors:
Elga Esposito Kazuhide Hayakawa Bum Ju Ahn Su Jing Chan Changhong Xing Anna C Liang Kyu-Won Kim Ken Arai Eng H Lo

J Neurochem 2018 07 16;146(2):160-172. Epub 2018 May 16.

Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1111/jnc.14337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105375PMC
July 2018

Special issue on protein acetylation: from molecular modification to human disease.

Authors:
Eun Ji Lee Ji Hae Seo Kyu-Won Kim

Exp Mol Med 2018 07 27;50(7):84. Epub 2018 Jul 27.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Korea.

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http://dx.doi.org/10.1038/s12276-018-0103-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063961PMC
July 2018

Versatility of ARD1/NAA10-mediated protein lysine acetylation.

Authors:
Tam Thuy Lu Vo Chul-Ho Jeong Sooyeun Lee Kyu-Won Kim Eunyoung Ha Ji Hae Seo

Exp Mol Med 2018 07 27;50(7):86. Epub 2018 Jul 27.

Department of Biochemistry, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.

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http://dx.doi.org/10.1038/s12276-018-0100-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063952PMC
July 2018

A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter.

Authors:
Takakuni Maki Yoon Kyung Choi Nobukazu Miyamoto Akihiro Shindo Anna C Liang Bum Ju Ahn Emiri T Mandeville Seiji Kaji Kanako Itoh Ji Hae Seo Irwin H Gelman Josephine Lok Ryosuke Takahashi Kyu-Won Kim Eng H Lo Ken Arai

Stem Cells 2018 05 22;36(5):751-760. Epub 2018 Jan 22.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/stem.2771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158PMC
May 2018

Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos.

Authors:
Hyeshik Chang Jinah Yeo Jeong-Gyun Kim Hyunjoon Kim Jaechul Lim Mihye Lee Hyun Ho Kim Jiyeon Ohk Hee-Yeon Jeon Hyunsook Lee Hosung Jung Kyu-Won Kim V Narry Kim

Mol Cell 2018 04;70(1):72-82.e7

Center for RNA Research, Institute for Basic Science, Seoul 08826, Korea; School of Biological Sciences, Seoul National University, Seoul 08826, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.03.004DOI Listing
April 2018

Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution.

Authors:
Hye Shin Lee Jinhyeok Choi Taekwon Son Hee-Jun Wee Sung-Jin Bae Ji Hae Seo Ji Hyun Park Soo Hyung Ryu Danbi Lee Myoung Kuk Jang Eunsil Yu Young-Hwa Chung Kyu-Won Kim

Exp Mol Med 2018 04 27;50(4):48. Epub 2018 Apr 27.

College of Pharmacy and Research, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Korea.

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http://dx.doi.org/10.1038/s12276-018-0074-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938025PMC
April 2018

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.

Authors:
Seungwon Ji Jin-Young Lee Jan Schrör Aloran Mazumder Dong Man Jang Sébastien Chateauvieux Michael Schnekenburger Che Ry Hong Christo Christov Hyoung Jin Kang Youngjo Lee Byung Woo Han Kyu-Won Kim Hee-Young Shin Mario Dicato Claudia Cerella Gabriele M König Barbora Orlikova Marc Diederich

Cancer Lett 2018 03 13;416:109-123. Epub 2017 Dec 13.

Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08626, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.12.011DOI Listing
March 2018

Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer.

Authors:
Jin-Young Lee Oualid Talhi Dongman Jang Claudia Cerella Anthoula Gaigneaux Kyu-Won Kim Jung Weon Lee Mario Dicato Khaldoun Bachari Byung Woo Han Artur M S Silva Barbora Orlikova Marc Diederich

Cancer Lett 2018 03 13;416:94-108. Epub 2017 Dec 13.

Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08626, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.12.007DOI Listing
March 2018

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.

Authors:
Naira F Z Schneider Claudia Cerella Jin-Young Lee Aloran Mazumder Kyung Rok Kim Annelise de Carvalho Jennifer Munkert Rodrigo M Pádua Wolfgang Kreis Kyu-Won Kim Christo Christov Mario Dicato Hyun-Jung Kim Byung Woo Han Fernão C Braga Cláudia M O Simões Marc Diederich

Front Pharmacol 2018 1;9:70. Epub 2018 Mar 1.

Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.3389/fphar.2018.00070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838923PMC
March 2018

Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.

Authors:
Esma Yagdi Efe Aloran Mazumder Jin-Young Lee Anthoula Gaigneaux Flavia Radogna Muhammad Jawad Nasim Christo Christov Claus Jacob Kyu-Won Kim Mario Dicato Patrick Chaimbault Claudia Cerella Marc Diederich

Cancer Lett 2017 12 21;410:139-157. Epub 2017 Sep 21.

College of Pharmacy, Seoul National University, Seoul, 08826, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.09.011DOI Listing
December 2017

Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice.

Authors:
Hoang Le Bum Ju Ahn Hye Shin Lee Anna Shin Sujin Chae Sung Yi Lee Min Wook Shin Eun-Ji Lee Jong-Ho Cha Taekwon Son Ji Hae Seo Hee-Jun Wee Hyo-Jong Lee Yongwoo Jang Eng H Lo Sejin Jeon Goo Taeg Oh Daesoo Kim Kyu-Won Kim

Mol Neurobiol 2017 11 5;54(9):7353-7368. Epub 2016 Nov 5.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 151-742, South Korea.

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http://dx.doi.org/10.1007/s12035-016-0207-6DOI Listing
November 2017

Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality.

Authors:
Jeong-Gyun Kim Sung-Jin Bae Hye Shin Lee Ji-Hyeon Park Kyu-Won Kim

PLoS One 2017 3;12(8):e0182047. Epub 2017 Aug 3.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and the Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542556PMC
October 2017

SAMHD1 acetylation enhances its deoxynucleotide triphosphohydrolase activity and promotes cancer cell proliferation.

Authors:
Eun Ji Lee Ji Hae Seo Ji-Hyeon Park Tam Thuy Lu Vo Sunho An Sung-Jin Bae Hoang Le Hye Shin Lee Hee-Jun Wee Danbi Lee Young-Hwa Chung Jeong A Kim Myoung-Kuk Jang Soo Hyung Ryu Ensil Yu Se Hwan Jang Zee Yong Park Kyu-Won Kim

Oncotarget 2017 Sep 31;8(40):68517-68529. Epub 2017 Jul 31.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.18632/oncotarget.19704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620274PMC
September 2017

Ninjurin1 Assembles Into a Homomeric Protein Complex Maintained by N-linked Glycosylation.

Authors:
Sung-Jin Bae Min Wook Shin Ran Hee Kim Dongyoon Shin Taekwon Son Hee-Jun Wee Kyu-Won Kim

J Cell Biochem 2017 08 18;118(8):2219-2230. Epub 2017 Apr 18.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Korea.

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http://doi.wiley.com/10.1002/jcb.25872
Publisher Site
http://dx.doi.org/10.1002/jcb.25872DOI Listing
August 2017

Hsp70 acetylation prevents caspase-dependent/independent apoptosis and autophagic cell death in cancer cells.

Authors:
Yoo Hoi Park Ji Hae Seo Ji-Hyeon Park Hye Shin Lee Kyu-Won Kim

Int J Oncol 2017 Aug 12;51(2):573-578. Epub 2017 Jun 12.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2017.4039DOI Listing
August 2017

ARD1-mediated aurora kinase A acetylation promotes cell proliferation and migration.

Authors:
Tam Thuy Lu Vo Ji-Hyeon Park Ji Hae Seo Eun Ji Lee Hoon Choi Sung-Jin Bae Hoang Le Sunho An Hye Shin Lee Hee-Jun Wee Kyu-Won Kim

Oncotarget 2017 Aug 18;8(34):57216-57230. Epub 2017 Jul 18.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and The Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.18632/oncotarget.19332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593637PMC
August 2017

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

Authors:
Michael Schnekenburger Eric Goffin Jin-Young Lee Jun Young Jang Aloran Mazumder Seungwon Ji Bernard Rogister Nafila Bouider Florence Lefranc Walter Miklos Véronique Mathieu Pascal de Tullio Kyu-Won Kim Mario Dicato Walter Berger Byung Woo Han Robert Kiss Bernard Pirotte Marc Diederich

J Med Chem 2017 06 25;60(11):4714-4733. Epub 2017 May 25.

Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University , 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00533DOI Listing
June 2017

YH18421, a novel GPR119 agonist exerts sustained glucose lowering and weight loss in diabetic mouse model.

Authors:
Yoo Hoi Park Hyun Ho Choi Dong Hoon Lee Soo Yong Chung Na Yeon Yang Do Hoon Kim Mi Kyeong Ju Tae Dong Han Su Youn Nam Kyu-Won Kim

Arch Pharm Res 2017 Jun 8;40(6):772-782. Epub 2017 Jun 8.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Korea.

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http://dx.doi.org/10.1007/s12272-017-0925-yDOI Listing
June 2017

Population genomics identifies the origin and signatures of selection of Korean weedy rice.

Authors:
Qiang He Kyu-Won Kim Yong-Jin Park

Plant Biotechnol J 2017 03 30;15(3):357-366. Epub 2016 Sep 30.

Department of Plant Resources, College of Industrial Science, Kongju National University, Yesan, 32439, Korea.

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http://dx.doi.org/10.1111/pbi.12630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316921PMC
March 2017

Structural environment built by AKAP12+ colon mesenchymal cells drives M2 macrophages during inflammation recovery.

Authors:
Jun-Mo Yang Hye Shin Lee Ji Hae Seo Ji-Hyeon Park Irwin H Gelman Eng H Lo Kyu-Won Kim

Sci Rep 2017 02 16;7:42723. Epub 2017 Feb 16.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 151-742, Korea.

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http://dx.doi.org/10.1038/srep42723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311874PMC
February 2017

How Can We Treat Cancer Disease Not Cancer Cells?

Authors:
Kyu-Won Kim Su-Jae Lee Woo-Young Kim Ji Hae Seo Ho-Young Lee

Cancer Res Treat 2017 Jan 26;49(1):1-9. Epub 2016 Dec 26.

Laboratory of Carcinogenesis and Drug Resistance, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2016.606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266380PMC
January 2017

Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors.

Authors:
Ho Shin Kim Mannkyu Hong Jihyae Ann Suyoung Yoon Cong-Truong Nguyen Su-Chan Lee Ho-Young Lee Young-Ger Suh Ji Hae Seo Hoon Choi Jun Yong Kim Kyu-Won Kim Joohwan Kim Young-Myeong Kim So-Jung Park Hyun-Ju Park Jeewoo Lee

Bioorg Med Chem 2016 11 30;24(22):6082-6093. Epub 2016 Sep 30.

Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.09.067DOI Listing
November 2016

Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury.

Authors:
Yoon Kyung Choi Takakuni Maki Emiri T Mandeville Seong-Ho Koh Kazuhide Hayakawa Ken Arai Young-Myeong Kim Michael J Whalen Changhong Xing Xiaoying Wang Kyu-Won Kim Eng H Lo

Nat Med 2016 11 26;22(11):1335-1341. Epub 2016 Sep 26.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1038/nm.4188DOI Listing
November 2016

AMP-activated protein kinase activator, HL156A reduces thioacetamide-induced liver fibrosis in mice and inhibits the activation of cultured hepatic stellate cells and macrophages.

Authors:
Hye Shin Lee Hyun-Sang Shin Jinhyeok Choi Sung-Jin Bae Hee-Jun Wee Taekwon Son Ji Hae Seo Ji-Hyeon Park Sung-Wuk Kim Kyu-Won Kim

Int J Oncol 2016 Oct 21;49(4):1407-14. Epub 2016 Jul 21.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2016.3627DOI Listing
October 2016

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

Authors:
Ji Hae Seo Ji-Hyeon Park Eun Ji Lee Tam Thuy Lu Vo Hoon Choi Jun Yong Kim Jae Kyung Jang Hee-Jun Wee Hye Shin Lee Se Hwan Jang Zee Yong Park Jaeho Jeong Kong-Joo Lee Seung-Hyeon Seok Jin Young Park Bong Jin Lee Mi-Ni Lee Goo Taeg Oh Kyu-Won Kim

Nat Commun 2016 10 6;7:12882. Epub 2016 Oct 6.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.1038/ncomms12882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059642PMC
October 2016

Genome-wide resequencing of KRICE_CORE reveals their potential for future breeding, as well as functional and evolutionary studies in the post-genomic era.

Authors:
Tae-Sung Kim Qiang He Kyu-Won Kim Min-Young Yoon Won-Hee Ra Feng Peng Li Wei Tong Jie Yu Win Htet Oo Buung Choi Eun-Beom Heo Byoung-Kook Yun Soon-Jae Kwon Soon-Wook Kwon Yoo-Hyun Cho Chang-Yong Lee Beom-Seok Park Yong-Jin Park

BMC Genomics 2016 05 26;17:408. Epub 2016 May 26.

Department of Plant Resources, College of Industrial Sciences, Kongju National University, Yesan, 340-702, Republic of Korea.

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http://dx.doi.org/10.1186/s12864-016-2734-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882841PMC
May 2016

CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation.

Authors:
Kazuhide Hayakawa Loc-Duyen D Pham Ji Hae Seo Nobukazu Miyamoto Takakuni Maki Yasukazu Terasaki Sava Sakadžić David Boas Klaus van Leyen Christian Waeber Kyu-Won Kim Ken Arai Eng H Lo

J Cereb Blood Flow Metab 2016 Apr 30;36(4):781-93. Epub 2015 Sep 30.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, USA.

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http://dx.doi.org/10.1177/0271678X15606148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821018PMC
April 2016

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.

Authors:
Cristina Florean Michael Schnekenburger Jin-Young Lee Kyung Rok Kim Aloran Mazumder Sungmi Song Jae-Myun Kim Cindy Grandjenette Jeoung-Gyun Kim Ah-Young Yoon Mario Dicato Kyu-Won Kim Christo Christov Byung-Woo Han Peter Proksch Marc Diederich

Oncotarget 2016 Apr;7(17):24027-49

Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.

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http://dx.doi.org/10.18632/oncotarget.8210DOI Listing
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April 2016

Time-calibrated phylogenomics of the classical swine fever viruses: genome-wide bayesian coalescent approach.

Authors:
Taehyung Kwon Sook Hee Yoon Kyu-Won Kim Kelsey Caetano-Anolles Seoae Cho Heebal Kim

PLoS One 2015 27;10(3):e0121578. Epub 2015 Mar 27.

Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, 151-921, Republic of Korea.

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March 2016

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity.

Authors:
Su-Chan Lee Hye-Young Min Hoon Choi Song Yi Bae Kwan Hee Park Seung Yeob Hyun Ho Jin Lee Jayoung Moon Shin-Hyung Park Jun Yong Kim Hongchan An So-Jung Park Ji Hae Seo Seungbeom Lee Young-Myeong Kim Hyun-Ju Park Sang Kook Lee Jeewoo Lee Jeeyeon Lee Kyu-Won Kim Young-Ger Suh Ho-Young Lee

Cancer Res 2016 Feb 8;76(3):686-99. Epub 2015 Dec 8.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.

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February 2016

Ninjurin1 regulates lipopolysaccharide-induced inflammation through direct binding.

Authors:
Min Wook Shin Sung-Jin Bae Hee-Jun Wee Hyo-Jong Lee Bum Ju Ahn Hoang Le Eun Ji Lee Ran Hee Kim Hye Shin Lee Ji Hae Seo Ji-Hyeon Park Kyu-Won Kim

Int J Oncol 2016 Feb 15;48(2):821-8. Epub 2015 Dec 15.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea.

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February 2016

Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling.

Authors:
Ji Hae Seo Takakuni Maki Mitsuyo Maeda Nobukazu Miyamoto Anna C Liang Kazuhide Hayakawa Loc-Duyen D Pham Fumihiko Suwa Akihiko Taguchi Tomohiro Matsuyama Masafumi Ihara Kyu-Won Kim Eng H Lo Ken Arai

PLoS One 2014 31;9(7):e103174. Epub 2014 Jul 31.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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November 2015

2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells.

Authors:
Cyril Sobolewski Jiyun Rhim Noémie Legrand Florian Muller Claudia Cerella Fabienne Mack Sébastien Chateauvieux Jeoung-Gyun Kim Ah-Young Yoon Kyu-Won Kim Mario Dicato Marc Diederich

J Pharmacol Exp Ther 2015 Nov 1;355(2):308-28. Epub 2015 Sep 1.

Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Luxembourg, Luxembourg (C.S., N.L., F.Mu. C.C., F.Ma., S.C., M.Dic.); Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea (J.R., S.C., M.Die.); and SNU-Harvard Neurovascular Protection Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea (J.G.K., A.Y.Y., K.W.K.)

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November 2015

Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors.

Authors:
Ho Shin Kim Mannkyu Hong Su-Chan Lee Ho-Young Lee Young-Ger Suh Dong-Chan Oh Ji Hae Seo Hoon Choi Jun Yong Kim Kyu-Won Kim Jeong Hun Kim Joohwan Kim Young-Myeong Kim So-Jung Park Hyun-Ju Park Jeewoo Lee

Eur J Med Chem 2015 Nov 30;104:157-64. Epub 2015 Sep 30.

Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 151-742, South Korea. Electronic address:

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November 2015

Akap12 is essential for the morphogenesis of muscles involved in zebrafish locomotion.

Authors:
Hyun-Ho Kim Jeong-gyun Kim Jinkyung Jeong Song-Yi Han Kyu-Won Kim

Differentiation 2014 Nov-Dec;88(4-5):106-16. Epub 2014 Dec 18.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Korea; Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 151-742, Korea. Electronic address:

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October 2015

Meteorin is upregulated in reactive astrocytes and functions as a negative feedback effector in reactive gliosis.

Authors:
Hye Shin Lee Soon-Hee Lee Jong-Ho Cha Ji Hae Seo Bum Ju Ahn Kyu-Won Kim

Mol Med Rep 2015 Aug 14;12(2):1817-23. Epub 2015 Apr 14.

SNU‑Harvard Neurovascular Protection Research Center, Department of Pharmacy, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151‑742, Republic of Korea.

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August 2015

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.

Authors:
Su-Chan Lee Hye-Young Min Hoon Choi Ho Shin Kim Kyong-Cheol Kim So-Jung Park Myeong A Seong Ji Hae Seo Hyun-Ju Park Young-Ger Suh Kyu-Won Kim Hyun-Seok Hong Hee Kim Min-Young Lee Jeewoo Lee Ho-Young Lee

Mol Pharmacol 2015 Aug 14;88(2):245-55. Epub 2015 May 14.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea (S.-C.L., H.-Y.M., H.C., H.S.K., K.-C.K., M.A.S., J.H.S., Y.-G.S., K.-W.K., J.L., H.-Y.L.); School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea (S.-J.P., H.-J.P.); and Medifron-DBT, Ansan, Republic of Korea (H.-S.H., H.K., M.-Y.L.)

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August 2015

Mutation of Oryza sativa CORONATINE INSENSITIVE 1b (OsCOI1b) delays leaf senescence.

Authors:
Sang-Hwa Lee Yasuhito Sakuraba Taeyoung Lee Kyu-Won Kim Gynheung An Han Yong Lee Nam-Chon Paek

J Integr Plant Biol 2015 Jun 30;57(6):562-76. Epub 2014 Sep 30.

Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 151-921, Korea.

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June 2015

Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: a prospective study.

Authors:
Kyu Won Kim Jae Jin Sung Hann Tchah Eell Ryoo Hye Kyung Cho Yong Han Sun Kang Ho Cho Dong Woo Son In Sang Jeon Yun Mi Kim

Korean J Pediatr 2015 Jun 22;58(6):211-7. Epub 2015 Jun 22.

Department of Nursing, Gachon University, Incheon, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510354PMC
June 2015

Nuclear translocation of hARD1 contributes to proper cell cycle progression.

Authors:
Ji-Hyeon Park Ji Hae Seo Hee-Jun Wee Tam Thuy Lu Vo Eun Ji Lee Hoon Choi Jong-Ho Cha Bum Ju Ahn Min Wook Shin Sung-Jin Bae Kyu-Won Kim

PLoS One 2014 18;9(8):e105185. Epub 2014 Aug 18.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136855PMC
April 2015

Efficacy of ketamine in improving pain after tonsillectomy in children: meta-analysis.

Authors:
Hye Kyung Cho Kyu Won Kim Yeon Min Jeong Ho Seok Lee Yeon Ji Lee Se Hwan Hwang

PLoS One 2014 30;9(6):e101259. Epub 2014 Jun 30.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

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February 2015

Different subcellular localizations and functions of human ARD1 variants.

Authors:
Ji Hae Seo Ji-Hyeon Park Eun Ji Lee Kyu-Won Kim

Int J Oncol 2015 Feb 21;46(2):701-7. Epub 2014 Nov 21.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea.

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February 2015

IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells.

Authors:
Emmanuella Guenova Yuliya Skabytska Wolfram Hoetzenecker Günther Weindl Karin Sauer Manuela Tham Kyu-Won Kim Ji-Hyeon Park Ji Hae Seo Desislava Ignatova Antonio Cozzio Mitchell P Levesque Thomas Volz Martin Köberle Susanne Kaesler Peter Thomas Reinhard Mailhammer Kamran Ghoreschi Knut Schäkel Boyko Amarov Martin Eichner Martin Schaller Rachael A Clark Martin Röcken Tilo Biedermann

Proc Natl Acad Sci U S A 2015 Feb 2;112(7):2163-8. Epub 2015 Feb 2.

Department of Dermatology, Eberhard Karls University, 72076 Tübingen, Germany; Department of Dermatology and Allergy, Technische Universität München, Munich, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343151PMC
February 2015

AKAP12 mediates barrier functions of fibrotic scars during CNS repair.

Authors:
Jong-Ho Cha Hee-Jun Wee Ji Hae Seo Bum Ju Ahn Ji-Hyeon Park Jun-Mo Yang Sae-Won Lee Eun Hee Kim Ok-Hee Lee Ji Hoe Heo Hyo-Jong Lee Irwin H Gelman Ken Arai Eng H Lo Kyu-Won Kim

PLoS One 2014 23;9(4):e94695. Epub 2014 Apr 23.

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997571PMC
January 2015

Autoacetylation regulates differentially the roles of ARD1 variants in tumorigenesis.

Authors:
Ji Hae Seo Ji-Hyeon Park Eun Ji Lee Tam Thuy Lu Vo Hoon Choi Jae Kyung Jang Hee-Jun Wee Bum Ju Ahn Jong-Ho Cha Min Wook Shin Kyu-Won Kim

Int J Oncol 2015 Jan 17;46(1):99-106. Epub 2014 Oct 17.

SNU-Harvard Neurovascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea.

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January 2015

Cetaceans evolution: insights from the genome sequences of common minke whales.

Authors:
Jung Youn Park Yong-Rock An Naohisa Kanda Chul-Min An Hye Suck An Jung-Ha Kang Eun Mi Kim Du-Hae An Hojin Jung Myunghee Joung Myung Hum Park Sook Hee Yoon Bo-Young Lee Taeheon Lee Kyu-Won Kim Won Cheoul Park Dong Hyun Shin Young Sub Lee Jaemin Kim Woori Kwak Hyeon Jeong Kim Young-Jun Kwon Sunjin Moon Yuseob Kim David W Burt Seoae Cho Heebal Kim

BMC Genomics 2015 Jan 22;16:13. Epub 2015 Jan 22.

Department of Agricultural Biotechnology, Seoul National University, Seoul, 151-921, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311506PMC
January 2015

Comparative genomics reveals insights into avian genome evolution and adaptation.

Authors:
Guojie Zhang Cai Li Qiye Li Bo Li Denis M Larkin Chul Lee Jay F Storz Agostinho Antunes Matthew J Greenwold Robert W Meredith Anders Ödeen Jie Cui Qi Zhou Luohao Xu Hailin Pan Zongji Wang Lijun Jin Pei Zhang Haofu Hu Wei Yang Jiang Hu Jin Xiao Zhikai Yang Yang Liu Qiaolin Xie Hao Yu Jinmin Lian Ping Wen Fang Zhang Hui Li Yongli Zeng Zijun Xiong Shiping Liu Long Zhou Zhiyong Huang Na An Jie Wang Qiumei Zheng Yingqi Xiong Guangbiao Wang Bo Wang Jingjing Wang Yu Fan Rute R da Fonseca Alonzo Alfaro-Núñez Mikkel Schubert Ludovic Orlando Tobias Mourier Jason T Howard Ganeshkumar Ganapathy Andreas Pfenning Osceola Whitney Miriam V Rivas Erina Hara Julia Smith Marta Farré Jitendra Narayan Gancho Slavov Michael N Romanov Rui Borges João Paulo Machado Imran Khan Mark S Springer John Gatesy Federico G Hoffmann Juan C Opazo Olle Håstad Roger H Sawyer Heebal Kim Kyu-Won Kim Hyeon Jeong Kim Seoae Cho Ning Li Yinhua Huang Michael W Bruford Xiangjiang Zhan Andrew Dixon Mads F Bertelsen Elizabeth Derryberry Wesley Warren Richard K Wilson Shengbin Li David A Ray Richard E Green Stephen J O'Brien Darren Griffin Warren E Johnson David Haussler Oliver A Ryder Eske Willerslev Gary R Graves Per Alström Jon Fjeldså David P Mindell Scott V Edwards Edward L Braun Carsten Rahbek David W Burt Peter Houde Yong Zhang Huanming Yang Jian Wang Erich D Jarvis M Thomas P Gilbert Jun Wang

Science 2014 Dec 11;346(6215):1311-20. Epub 2014 Dec 11.

China National GeneBank, Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, 518083, China. Macau University of Science and Technology, Avenida Wai long, Taipa, Macau 999078, China. Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark. Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Department of Medicine, University of Hong Kong, Hong Kong.

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December 2014

"Standby" EMT and "immune cell trapping" structure as novel mechanisms for limiting neuronal damage after CNS injury.

Authors:
Jong-Ho Cha Kyu-Won Kim

Neural Regen Res 2014 Dec;9(23):2032-5

SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 151-742, Korea ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul 151-742, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316460PMC
December 2014

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors.

Authors:
Dong Hyun Jo Hongchan An Dong-Jo Chang Yi-Yong Baek Chang Sik Cho Hyoung Oh Jun So-Jung Park Jin Hyoung Kim Ho-Young Lee Kyu-Won Kim Jeewoo Lee Hyun-Ju Park Young-Myeong Kim Young-Ger Suh Jeong Hun Kim

J Mol Med (Berl) 2014 Oct 31;92(10):1083-92. Epub 2014 May 31.

Fight against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, 110-744, Republic of Korea.

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http://dx.doi.org/10.1007/s00109-014-1168-8DOI Listing
October 2014

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice.

Authors:
Sung Wook Park Jin Hyoung Kim Inhee Mook-Jung Kyu-Won Kim Woo Jin Park Kyu Hyung Park Jeong Hun Kim

Neurobiol Aging 2014 Sep 15;35(9):2013-20. Epub 2014 Mar 15.

Fight against Angiogenesis-Related Blindness Laboratory, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea; Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea. Electronic address:

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September 2014

Angiopoietin 2 induces pericyte apoptosis via α3β1 integrin signaling in diabetic retinopathy.

Authors:
Sung Wook Park Jang-Hyuk Yun Jin Hyoung Kim Kyu-Won Kim Chung-Hyun Cho Jeong Hun Kim

Diabetes 2014 Sep 10;63(9):3057-68. Epub 2014 Apr 10.

Fight against Angiogenesis-Related Blindness Laboratory, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea

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September 2014

Prompt meningeal reconstruction mediated by oxygen-sensitive AKAP12 scaffolding protein after central nervous system injury.

Authors:
Jong-Ho Cha Hee-Jun Wee Ji Hae Seo Bum Ju Ahn Ji-Hyeon Park Jun-Mo Yang Sae-Won Lee Ok-Hee Lee Hyo-Jong Lee Irwin H Gelman Ken Arai Eng H Lo Kyu-Won Kim

Nat Commun 2014 Sep 17;5:4952. Epub 2014 Sep 17.

1] SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Korea [2] Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1038/ncomms5952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348065PMC
September 2014

TM4SF5 suppression disturbs integrin α5-related signalling and muscle development in zebrafish.

Authors:
Yoon-Ju Choi Hyun Ho Kim Jeong-Gyun Kim Hye-Jin Kim Minkyung Kang Mi-Sook Lee Jihye Ryu Haeng Eun Song Seo Hee Nam Doohyung Lee Kyu-Won Kim Jung Weon Lee

Biochem J 2014 Aug;462(1):89-101

*Department of Pharmacy, Research Institute of Pharmaceutical Sciences, Tumor Microenvironment Global Core Research Center, Medicinal Bioconvergence Research Center, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.

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August 2014

Nuclear expression of p53 in mature tumor endothelium of retinoblastoma.

Authors:
Byung Joo Lee Jin Hyoung Kim Dong Hyun Jo Kyu-Won Kim Young Suk Yu Jeong Hun Kim

Oncol Rep 2014 Aug 5;32(2):801-7. Epub 2014 Jun 5.

Fight Against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.

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August 2014

Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics.

Authors:
Bum Ju Ahn Hoang Le Min Wook Shin Sung-Jin Bae Eun Ji Lee Sung Yi Lee Ju Hee Yang Hee-Jun Wee Jong-Ho Cha Ji Hae Seo Hye Shin Lee Hyo-Jong Lee Ken Arai Eng H Lo Sejin Jeon Goo Taeg Oh Woo Jean Kim Ji-Kan Ryu Jun-Kyu Suh Kyu-Won Kim

J Biol Chem 2014 Aug 10;289(32):21926-36. Epub 2014 Jun 10.

From the SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Korea, the Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul 151-742, Korea,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139210PMC
August 2014

Sonic hedgehog secreted by neurons regulates angiopoietin expression in neighboring fibroblasts.

Authors:
Woo Jean Kim Sae-Won Lee Kyu-Won Kim

Int J Mol Med 2014 Jul 2;34(1):213-8. Epub 2014 May 2.

Division of Pharmaceutical Biosciences, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.

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July 2014

Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse.

Authors:
Guo Nan Yin Min Ji Choi Woo Jean Kim Mi-Hye Kwon Kang-Moon Song Jin-Mi Park Nando Dulal Das Ki-Dong Kwon Dulguun Batbold Goo Taeg Oh Gou Young Koh Kyu-Won Kim Ji-Kan Ryu Jun-Kyu Suh

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):E2731-40. Epub 2014 Jun 16.

National Research Center for Sexual Medicine andDepartment of Urology, Inha University School of Medicine, Incheon 400-711, Korea;

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http://dx.doi.org/10.1073/pnas.1403471111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084468PMC
July 2014

Differential Evolution between Monotocous and Polytocous Species.

Authors:
Hyeonju Ahn Kyu-Won Kim Hyeon Jeong Kim Seoae Cho Heebal Kim

Asian-Australas J Anim Sci 2014 Apr;27(4):464-70

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-742, Korea .

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http://dx.doi.org/10.5713/ajas.2013.13696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093529PMC
April 2014

Crosstalk between cerebral endothelium and oligodendrocyte.

Authors:
Nobukazu Miyamoto Loc-Duyen D Pham Ji Hae Seo Kyu-Won Kim Eng H Lo Ken Arai

Cell Mol Life Sci 2014 Mar 17;71(6):1055-66. Epub 2013 Oct 17.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, MGH East 149-2401, Charlestown, MA, 02129, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944198PMC
March 2014

Allosteric regulation of pathologic angiogenesis: potential application for angiogenesis-related blindness.

Authors:
Dong Hyun Jo Jin Hyoung Kim Kyu-Won Kim Young-Ger Suh Jeong Hun Kim

Arch Pharm Res 2014 Mar 7;37(3):285-98. Epub 2014 Jan 7.

Fight Against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, 110-744, Korea.

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March 2014

De Novo assembly and comparative analysis of the Enterococcus faecalis genome (KACC 91532) from a Korean Neonate.

Authors:
Jun Sang Ham Woori Kwak Oun Ki Chang Gi Sung Han Seok Geun Jeong Kuk Hwan Seol Hyoun Wook Kim Geun Ho Kang Beom Young Park Hyun-Jeong Lee Jong Geun Kim Kyu-Won Kim Samsun Sung Taeheon Lee Seoae Cho Heebal Kim

J Microbiol Biotechnol 2013 ;23(7):966-73

Animal Products Research and Development Division, National Institute of Animal Science, Rural Development Administration, Suwon, 441-706, Republic of Korea.

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February 2014

Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice.

Authors:
Bum Ju Ahn Hoang Le Min Wook Shin Sung-Jin Bae Eun Ji Lee Hee-Jun Wee Jong-Ho Cha Hyo-Jong Lee Hye Shin Lee Jeong Hun Kim Chang-Yeon Kim Ji Hae Seo Eng H Lo Sejin Jeon Mi-Ni Lee Goo Taeg Oh Guo Nan Yin Ji-Kan Ryu Jun-Kyu Suh Kyu-Won Kim

J Biol Chem 2014 Feb 17;289(6):3328-38. Epub 2013 Dec 17.

From the SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences and.

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http://dx.doi.org/10.1074/jbc.M113.498212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916537PMC
February 2014

TRAIL negatively regulates VEGF-induced angiogenesis via caspase-8-mediated enzymatic and non-enzymatic functions.

Authors:
Hee-Jun Na Jong-Yun Hwang Kwang-Soon Lee Yoon Kyung Choi Jongseon Choe Ji-Yoon Kim Hyo-Eun Moon Kyu-Won Kim Gou Young Koh Hansoo Lee Dooil Jeoung Moo-Ho Won Kwon-Soo Ha Young-Guen Kwon Young-Myeong Kim

Angiogenesis 2014 Jan 5;17(1):179-94. Epub 2013 Oct 5.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 200-701, Korea.

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http://dx.doi.org/10.1007/s10456-013-9387-0DOI Listing
January 2014

Anti-inflammatory effects of chlorogenic acid in lipopolysaccharide-stimulated RAW 264.7 cells.

Authors:
Su Jung Hwang Yong-Wan Kim Yohan Park Hyo-Jong Lee Kyu-Won Kim

Inflamm Res 2014 Jan 15;63(1):81-90. Epub 2013 Oct 15.

College of Pharmacy, Inje University, 607 Obang-dong, Gimhae, Gyungnam, 621-749, Republic of Korea.

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http://link.springer.com/10.1007/s00011-013-0674-4
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January 2014

Suppression of protein kinase C-ζ attenuates vascular leakage via prevention of tight junction protein decrease in diabetic retinopathy.

Authors:
Hyun Beom Song Hyoung-Oh Jun Jin Hyoung Kim Young Suk Yu Kyu Won Kim Jeong Hun Kim

Biochem Biophys Res Commun 2014 Jan 14;444(1):63-8. Epub 2014 Jan 14.

Fight Against Angiogenesis-Related Blindness Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Republic of Korea; Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.01.002DOI Listing
January 2014

Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice.

Authors:
Nobukazu Miyamoto Takakuni Maki Loc-Duyen D Pham Kazuhide Hayakawa Ji Hae Seo Emiri T Mandeville Joseph B Mandeville Kyu-Won Kim Eng H Lo Ken Arai

Stroke 2013 Dec 26;44(12):3516-21. Epub 2013 Sep 26.

From the Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (N.M., T.M., L.-D.D.P., K.H., J.H.S., E.T.M., E.H.L., K.A.); Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA (J.B.M.); and NeuroVascular Coordination Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences (J.H.S., K.-W.K.) and Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology (K.-W.K.), Seoul National University, Seoul, Korea.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.113.002813
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985753PMC
December 2013

Anti-apoptotic effect of clusterin on cisplatin-induced cell death of retinoblastoma cells.

Authors:
Hyun Beom Song Hyoung-Oh Jun Jin Hyoung Kim Young Suk Yu Kyu-Won Kim Bon Hong Min Jeong Hun Kim

Oncol Rep 2013 Dec 1;30(6):2713-8. Epub 2013 Oct 1.

Fight against Angiogenesis-Related Blindness Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.

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http://dx.doi.org/10.3892/or.2013.2764DOI Listing
December 2013

The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signaling in zebrafish.

Authors:
Hyouk-Bum Kwon Shigetomo Fukuhara Kazuhide Asakawa Koji Ando Takeru Kashiwada Koichi Kawakami Masahiko Hibi Young-Guen Kwon Kyu-Won Kim Kari Alitalo Naoki Mochizuki

Development 2013 Oct;140(19):4081-90

Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dev.biologists.org/lookup/doi/10.1242/dev.091702
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913045PMC
October 2013

Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis.

Authors:
Sae-Won Lee Joo-Yun Won Woo Jean Kim Jaewon Lee Kyung-Hee Kim Seock-Won Youn Ju-Young Kim Eun Ju Lee Yong-Jin Kim Kyu-Won Kim Hyo-Soo Kim

Mol Ther 2013 Sep 13;21(9):1767-77. Epub 2013 Jun 13.

Department of Internal Medicine and Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea.

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http://dx.doi.org/10.1038/mt.2013.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953993PMC
September 2013

Age-related decline in oligodendrogenesis retards white matter repair in mice.

Authors:
Nobukazu Miyamoto Loc-Duyen D Pham Kazuhide Hayakawa Toshinori Matsuzaki Ji Hae Seo Caroline Magnain Cenk Ayata Kyu-Won Kim David Boas Eng H Lo Ken Arai

Stroke 2013 Sep 23;44(9):2573-8. Epub 2013 Jul 23.

Department of Radiology and Neurology, Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, MA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.113.001530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818687PMC
September 2013

Erectile dysfunction precedes other systemic vascular diseases due to incompetent cavernous endothelial cell-cell junctions.

Authors:
Ji-Kan Ryu Hai-Rong Jin Guo Nan Yin Mi-Hye Kwon Kang-Moon Song Min Ji Choi Jin-Mi Park Nando Dulal Das Ki-Dong Kwon Dulguun Batbold Tack Lee Zhen Li Gao Kyu-Won Kim Woo Jean Kim Jun-Kyu Suh

J Urol 2013 Aug 28;190(2):779-89. Epub 2013 Feb 28.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon, Republic of Korea.

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http://dx.doi.org/10.1016/j.juro.2013.02.100DOI Listing
August 2013

Identification of differentially evolved genes: an alternative approach to detection of accelerated molecular evolution from genome-wide comparative data.

Authors:
Kyu-Won Kim David W Burt Heebal Kim Seoae Cho

Evol Bioinform Online 2013 28;9:285-99. Epub 2013 Jul 28.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.4137/EBO.S12166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733729PMC
August 2013

Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells.

Authors:
Yun-Hee Bae Jong Hyo Ryu Hyun-Joo Park Kwang Rok Kim Hee-Jun Wee Ok-Hee Lee Hye-Ock Jang Moon-Kyoung Bae Kyu-Won Kim Soo-Kyung Bae

Korean J Physiol Pharmacol 2013 Aug 30;17(4):291-7. Epub 2013 Jul 30.

Department of Dental Pharmacology, School of Dentistry, Yangsan Campus of Pusan National University, Yangsan 626-870, Korea.

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http://dx.doi.org/10.4196/kjpp.2013.17.4.291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741485PMC
August 2013

The duck genome and transcriptome provide insight into an avian influenza virus reservoir species.

Authors:
Yinhua Huang Yingrui Li David W Burt Hualan Chen Yong Zhang Wubin Qian Heebal Kim Shangquan Gan Yiqiang Zhao Jianwen Li Kang Yi Huapeng Feng Pengyang Zhu Bo Li Qiuyue Liu Suan Fairley Katharine E Magor Zhenlin Du Xiaoxiang Hu Laurie Goodman Hakim Tafer Alain Vignal Taeheon Lee Kyu-Won Kim Zheya Sheng Yang An Steve Searle Javier Herrero Martien A M Groenen Richard P M A Crooijmans Thomas Faraut Qingle Cai Robert G Webster Jerry R Aldridge Wesley C Warren Sebastian Bartschat Stephanie Kehr Manja Marz Peter F Stadler Jacqueline Smith Robert H S Kraus Yaofeng Zhao Liming Ren Jing Fei Mireille Morisson Pete Kaiser Darren K Griffin Man Rao Frederique Pitel Jun Wang Ning Li

Nat Genet 2013 Jul 9;45(7):776-783. Epub 2013 Jun 9.

State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1038/ng.2657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003391PMC
July 2013

The anti-angiogenic activities of glycyrrhizic acid in tumor progression.

Authors:
Kil-Jung Kim Jae-Sun Choi Kyu-Won Kim Joo-Won Jeong

Phytother Res 2013 Jun 16;27(6):841-6. Epub 2012 Aug 16.

Department of Biomedical Science, Kyung Hee University, Seoul, Korea.

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http://dx.doi.org/10.1002/ptr.4800DOI Listing
June 2013

Nerve injury-induced protein 1 (Ninjurin-1) is a novel therapeutic target for cavernous nerve injury-induced erectile dysfunction in mice.

Authors:
Guo Nan Yin Woo Jean Kim Hai-Rong Jin Mi-Hye Kwon Kang-Moon Song Min Ji Choi Jin-Mi Park Nando Dulal Das Ki-Dong Kwon Dulguun Batbold Kyu-Won Kim Ji-Kan Ryu Jun-Kyu Suh

J Sex Med 2013 Jun 2;10(6):1488-501. Epub 2013 Apr 2.

Department of Urology, National Research Center for Sexual Medicine, Inha University School of Medicine, Incheon, Korea.

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http://dx.doi.org/10.1111/jsm.12129DOI Listing
June 2013

A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer.

Authors:
Young-Ah Suh Jai-Hyun Kim Myung A Sung Hye-Jin Boo Hye Jeong Yun Sun-Hye Lee Hyo-Jong Lee Hye-Young Min Young-Ger Suh Kyu-Won Kim Ho-Young Lee

Cancer Lett 2013 May 21;332(1):102-9. Epub 2013 Jan 21.

Institute for Innovative Cancer Research, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea.

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http://dx.doi.org/10.1016/j.canlet.2013.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638119PMC
May 2013

Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model.

Authors:
Kil-Jung Kim Jae-Sun Choi Insug Kang Kyu-Won Kim Chul-Ho Jeong Joo-Won Jeong

J Pineal Res 2013 Apr 27;54(3):264-70. Epub 2012 Aug 27.

Department of Biomedical Science, Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea.

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http://dx.doi.org/10.1111/j.1600-079X.2012.01030.xDOI Listing
April 2013

High-mobility group box 1 from reactive astrocytes enhances the accumulation of endothelial progenitor cells in damaged white matter.

Authors:
Kazuhide Hayakawa Nobukazu Miyamoto Ji Hae Seo Loc-Duyen D Pham Kyu-Won Kim Eng H Lo Ken Arai

J Neurochem 2013 Apr 28;125(2):273-80. Epub 2012 Dec 28.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1111/jnc.12120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604050PMC
April 2013

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury.

Authors:
Ji Hae Seo Nobukazu Miyamoto Kazuhide Hayakawa Loc-Duyen D Pham Takakuni Maki Cenk Ayata Kyu-Won Kim Eng H Lo Ken Arai

J Clin Invest 2013 Feb 2;123(2):782-6. Epub 2013 Jan 2.

Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI65863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561802PMC
February 2013

Nerve growth factor-mediated vascular endothelial growth factor expression of astrocyte in retinal vascular development.

Authors:
You Sun Kim Dong Hyun Jo Hanjae Lee Jin Hyoung Kim Kyu-Won Kim Jeong Hun Kim

Biochem Biophys Res Commun 2013 Feb 18;431(4):740-5. Epub 2013 Jan 18.

Fight against Angiogenesis-Related Blindness Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul 110-744, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.01.045DOI Listing
February 2013

NK cell-associated antigen expression in retinoblastoma animal model.

Authors:
Eun Kyoung Lee Dong Hyun Jo Jin Hyoung Kim Young Suk Yu Kyu-Won Kim Jeong Hun Kim

Cancer Invest 2013 Jan 16;31(1):67-73. Epub 2012 Nov 16.

Fight Against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.

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http://dx.doi.org/10.3109/07357907.2012.743554DOI Listing
January 2013

Neurovascular matrix metalloproteinases and the blood-brain barrier.

Authors:
Ji Hae Seo Shuzhen Guo Josephine Lok Deepti Navaratna Michael J Whalen Kyu-Won Kim Eng H Lo

Curr Pharm Des 2012 ;18(25):3645-8

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814178PMC
http://dx.doi.org/10.2174/138161212802002742DOI Listing
December 2012

Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.

Authors:
Dong-Jo Chang Hongchan An Kyoung-suk Kim Hyun Ho Kim Jinkyung Jung Jung Min Lee Nam-Jung Kim Young Taek Han Hwayoung Yun Sujin Lee Geumwoo Lee Seungbeom Lee Ju Sung Lee Jong-Ho Cha Ji-Hyeon Park Ji Won Park Su-Chan Lee Sang Geon Kim Jeong Hun Kim Ho-Young Lee Kyu-Won Kim Young-Ger Suh

J Med Chem 2012 Dec 7;55(24):10863-84. Epub 2012 Dec 7.

College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.

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http://pubs.acs.org/doi/10.1021/jm301488q
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December 2012

The N-terminal ectodomain of Ninjurin1 liberated by MMP9 has chemotactic activity.

Authors:
Bum Ju Ahn Hoang Le Min Wook Shin Sung-Jin Bae Eun Ji Lee Hee-Jun Wee Jong Ho Cha Ji-Hyeon Park Hye Shin Lee Hyo-Jong Lee Hyunsook Jung Zee-Yong Park Sang Ho Park Byung Woo Han Ji Hae Seo Eng H Lo Kyu-Won Kim

Biochem Biophys Res Commun 2012 Nov 7;428(4):438-44. Epub 2012 Nov 7.

NeuroVascular Coordination Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2012.10.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712845PMC
November 2012

Analyses of pig genomes provide insight into porcine demography and evolution.

Authors:
Martien A M Groenen Alan L Archibald Hirohide Uenishi Christopher K Tuggle Yasuhiro Takeuchi Max F Rothschild Claire Rogel-Gaillard Chankyu Park Denis Milan Hendrik-Jan Megens Shengting Li Denis M Larkin Heebal Kim Laurent A F Frantz Mario Caccamo Hyeonju Ahn Bronwen L Aken Anna Anselmo Christian Anthon Loretta Auvil Bouabid Badaoui Craig W Beattie Christian Bendixen Daniel Berman Frank Blecha Jonas Blomberg Lars Bolund Mirte Bosse Sara Botti Zhan Bujie Megan Bystrom Boris Capitanu Denise Carvalho-Silva Patrick Chardon Celine Chen Ryan Cheng Sang-Haeng Choi William Chow Richard C Clark Christopher Clee Richard P M A Crooijmans Harry D Dawson Patrice Dehais Fioravante De Sapio Bert Dibbits Nizar Drou Zhi-Qiang Du Kellye Eversole João Fadista Susan Fairley Thomas Faraut Geoffrey J Faulkner Katie E Fowler Merete Fredholm Eric Fritz James G R Gilbert Elisabetta Giuffra Jan Gorodkin Darren K Griffin Jennifer L Harrow Alexander Hayward Kerstin Howe Zhi-Liang Hu Sean J Humphray Toby Hunt Henrik Hornshøj Jin-Tae Jeon Patric Jern Matthew Jones Jerzy Jurka Hiroyuki Kanamori Ronan Kapetanovic Jaebum Kim Jae-Hwan Kim Kyu-Won Kim Tae-Hun Kim Greger Larson Kyooyeol Lee Kyung-Tai Lee Richard Leggett Harris A Lewin Yingrui Li Wansheng Liu Jane E Loveland Yao Lu Joan K Lunney Jian Ma Ole Madsen Katherine Mann Lucy Matthews Stuart McLaren Takeya Morozumi Michael P Murtaugh Jitendra Narayan Dinh Truong Nguyen Peixiang Ni Song-Jung Oh Suneel Onteru Frank Panitz Eung-Woo Park Hong-Seog Park Geraldine Pascal Yogesh Paudel Miguel Perez-Enciso Ricardo Ramirez-Gonzalez James M Reecy Sandra Rodriguez-Zas Gary A Rohrer Lauretta Rund Yongming Sang Kyle Schachtschneider Joshua G Schraiber John Schwartz Linda Scobie Carol Scott Stephen Searle Bertrand Servin Bruce R Southey Goran Sperber Peter Stadler Jonathan V Sweedler Hakim Tafer Bo Thomsen Rashmi Wali Jian Wang Jun Wang Simon White Xun Xu Martine Yerle Guojie Zhang Jianguo Zhang Jie Zhang Shuhong Zhao Jane Rogers Carol Churcher Lawrence B Schook

Nature 2012 Nov;491(7424):393-8

Animal Breeding and Genomics Centre, Wageningen University, De Elst 1, 6708 WD, Wageningen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566564PMC
November 2012

Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF.

Authors:
Sae-Won Lee Han-Kyul Jeong Ji-Young Lee Jimin Yang Eun Ju Lee Su-Yeon Kim Seock-Won Youn Jaewon Lee Woo Jean Kim Kyu-Won Kim Jeong Mook Lim Jong-Wan Park Young-Bae Park Hyo-Soo Kim

EMBO Mol Med 2012 Sep 23;4(9):924-38. Epub 2012 Jul 23.

Department of Internal Medicine, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Korea.

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http://embomolmed.embopress.org/cgi/doi/10.1002/emmm.2011011
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http://dx.doi.org/10.1002/emmm.201101107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491825PMC
September 2012

Anti-inflammatory effects of arbutin in lipopolysaccharide-stimulated BV2 microglial cells.

Authors:
Hyo-Jong Lee Kyu-Won Kim

Inflamm Res 2012 Aug 10;61(8):817-25. Epub 2012 Apr 10.

College of Pharmacy, Inje University, Gimhae, Gyungnam, South Korea.

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http://dx.doi.org/10.1007/s00011-012-0474-2DOI Listing
August 2012

Suppression of HIF-1α by Valproic Acid Sustains Self-Renewal of Mouse Embryonic Stem Cells under Hypoxia In Vitro.

Authors:
Hyo-Jong Lee Kyu-Won Kim

Biomol Ther (Seoul) 2012 May;20(3):280-5

College of Pharmacy, Inje University, Gimhae 621-749.

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http://dx.doi.org/10.4062/biomolther.2012.20.3.280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794524PMC
May 2012