Kyu-Seon Oh

Assaying Homodimers of NF-κB in Live Single Cells.

Authors:

Erik W Martin Sayantan Chakraborty Diego M Presman Francesco Tomassoni Ardori Kyu-Seon Oh Mary Kaileh Lino Tessarollo Myong-Hee Sung

Front Immunol 2019 7;10:2609. Epub 2019 Nov 7.

Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.

View Article and Find Full Text PDF

November 2020

XL-DNase-seq: improved footprinting of dynamic transcription factors.

Authors:

Kyu-Seon Oh Jisu Ha Songjoon Baek Myong-Hee Sung

Epigenetics Chromatin 2019 06 4;12(1):30. Epub 2019 Jun 4.

Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA.

View Article and Find Full Text PDF

June 2019

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression.

Authors:

Kyu-Seon Oh Rachel A Gottschalk Nicolas W Lounsbury Jing Sun Michael G Dorrington Songjoon Baek Guangping Sun Ze Wang Kathleen S Krauss Joshua D Milner Bhaskar Dutta Gordon L Hager Myong-Hee Sung Iain D C Fraser

J Immunol 2018 07 13;201(2):757-771. Epub 2018 Jun 13.

Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;

View Article and Find Full Text PDF

July 2018

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action.

Authors:

Kyu-Seon Oh Heta Patel Rachel A Gottschalk Wai Shing Lee Songjoon Baek Iain D C Fraser Gordon L Hager Myong-Hee Sung

Immunity 2017 08 8;47(2):298-309.e5. Epub 2017 Aug 8.

Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

View Article and Find Full Text PDF

August 2017

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.

Authors:

Jing Sun Ning Li Kyu-Seon Oh Bhaskar Dutta Sharat J Vayttaden Bin Lin Thomas S Ebert Dominic De Nardo Joie Davis Rustam Bagirzadeh Nicolas W Lounsbury Chandrashekhar Pasare Eicke Latz Veit Hornung Iain D C Fraser

Sci Signal 2016 Jan 5;9(409):ra3. Epub 2016 Jan 5.

Signaling Systems Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

View Article and Find Full Text PDF

January 2016

Ocular manifestations of xeroderma pigmentosum: long-term follow-up highlights the role of DNA repair in protection from sun damage.

Ophthalmology 2013 Jul 16;120(7):1324-36. Epub 2013 Apr 16.

National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article and Find Full Text PDF

July 2013

Ancient origin of a Japanese xeroderma pigmentosum founder mutation.

Authors:

Kyoko Imoto Carine Nadem Shin-Ichi Moriwaki Chikako Nishigori Kyu-Seon Oh Sikandar G Khan Alisa M Goldstein Kenneth H Kraemer

J Dermatol Sci 2013 Feb 9;69(2):175-6. Epub 2012 Nov 9.

View Article and Find Full Text PDF

February 2013

Effect of mutations in XPD(ERCC2) on pregnancy and prenatal development in mothers of patients with trichothiodystrophy or xeroderma pigmentosum.

Authors:

Deborah Tamura Sikandar G Khan Melissa Merideth John J DiGiovanna Margaret A Tucker Alisa M Goldstein Kyu-Seon Oh Takahiro Ueda Jennifer Boyle Mansi Sarihan Kenneth H Kraemer

Eur J Hum Genet 2012 Dec 23;20(12):1308-10. Epub 2012 May 23.

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-4258, USA.

View Article and Find Full Text PDF

December 2012

Ocular manifestations of trichothiodystrophy.

Authors:

Brian P Brooks Amy H Thompson Janine A Clayton Chi-Chao Chan Deborah Tamura Wadih M Zein Delphine Blain Casey Hadsall John Rowan Kristen E Bowles Sikandar G Khan Takahiro Ueda Jennifer Boyle Kyu-Seon Oh John J DiGiovanna Kenneth H Kraemer

Ophthalmology 2011 Dec 28;118(12):2335-42. Epub 2011 Sep 28.

National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article and Find Full Text PDF

December 2011

High-risk pregnancy and neonatal complications in the DNA repair and transcription disorder trichothiodystrophy: report of 27 affected pregnancies.

Authors:

Deborah Tamura Melissa Merideth John J DiGiovanna Xiaolong Zhou Margaret A Tucker Alisa M Goldstein Brian P Brooks Sikandar G Khan Kyu-Seon Oh Takahiro Ueda Jennifer Boyle Roxana Moslehi Kenneth H Kraemer

Prenat Diagn 2011 Nov 29;31(11):1046-53. Epub 2011 Jul 29.

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

View Article and Find Full Text PDF

November 2011

Nucleotide excision repair proteins rapidly accumulate but fail to persist in human XP-E (DDB2 mutant) cells.

Authors:

Kyu-Seon Oh Kyoko Imoto Steffen Emmert Deborah Tamura John J DiGiovanna Kenneth H Kraemer

Photochem Photobiol 2011 May-Jun;87(3):729-33. Epub 2011 Mar 9.

DNA Repair Section, Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

View Article and Find Full Text PDF

September 2011

Multiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.

Authors:

Kyu-Seon Oh Steffen Emmert Deborah Tamura John J DiGiovanna Kenneth H Kraemer

J Invest Dermatol 2011 Mar 25;131(3):785-8. Epub 2010 Nov 25.

View Article and Find Full Text PDF

March 2011

Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair.

Authors:

Porcia T Bradford Alisa M Goldstein Deborah Tamura Sikandar G Khan Takahiro Ueda Jennifer Boyle Kyu-Seon Oh Kyoko Imoto Hiroki Inui Shin-Ichi Moriwaki Steffen Emmert Kristen M Pike Arati Raziuddin Teri M Plona John J DiGiovanna Margaret A Tucker Kenneth H Kraemer

J Med Genet 2011 Mar 19;48(3):168-76. Epub 2010 Nov 19.

Genetic Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, Maryland 20892-4258, USA.

View Article and Find Full Text PDF

March 2011

UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells.

Authors:

Kyu-Seon Oh Michael Bustin Sharlyn J Mazur Ettore Appella Kenneth H Kraemer

DNA Repair (Amst) 2011 Jan 13;10(1):5-15. Epub 2010 Oct 13.

DNA Repair Section, Dermatology Branch, CCR, National Cancer Institute, Bethesda, MD 20892, USA.

View Article and Find Full Text PDF

January 2011

Pseudomonas aeruginosa exotoxin A reduces chemoresistance of oral squamous carcinoma cell via inhibition of heat shock proteins 70 (HSP70).

Authors:

Sang Rye Park Kyoung Duk Lee Uk Kyu Kim Young Gi Gil Kyu Seon Oh Bong Soo Park Gyoo Cheon Kim

Yonsei Med J 2010 Sep;51(5):708-16

Department of Oral Anatomy, School of Dentistry, Research Institute for Oral Biotechnology, Pusan National University, Yangsan, Korea.

View Article and Find Full Text PDF

September 2010

XPC branch-point sequence mutations disrupt U2 snRNP binding, resulting in abnormal pre-mRNA splicing in xeroderma pigmentosum patients.

Authors:

Sikandar G Khan Koji Yamanegi Zhi-Ming Zheng Jennifer Boyle Kyoko Imoto Kyu-Seon Oh Carl C Baker Engin Gozukara Ahmet Metin Kenneth H Kraemer

Hum Mutat 2010 Feb;31(2):167-75

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

View Article and Find Full Text PDF

February 2010

Unexpected occurrence of xeroderma pigmentosum in an uncle and nephew.

Authors:

Stéphanie Christen-Zaech Kyoko Imoto Sikandar G Khan Kyu-Seon Oh Deborah Tamura John J Digiovanna Jennifer Boyle Nickolas J Patronas Raphael Schiffmann Kenneth H Kraemer Amy S Paller

Arch Dermatol 2009 Nov;145(11):1285-91

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

View Article and Find Full Text PDF

November 2009

Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.

Authors:

Yun Wang John J Digiovanna Jere B Stern Thomas J Hornyak Mark Raffeld Sikandar G Khan Kyu-Seon Oh M Christine Hollander Philip A Dennis Kenneth H Kraemer

Proc Natl Acad Sci U S A 2009 Apr 27;106(15):6279-84. Epub 2009 Mar 27.

Basic Research Laboratory, Laboratory of Pathology, Dermatology Branch, Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

View Article and Find Full Text PDF

April 2009