Publications by authors named "Kyriacos Kyriacou"

66Publications

NGS Panel Testing of Triple-Negative Breast Cancer Patients in Cyprus: A Study of -Negative Cases.

Cancers (Basel) 2020 Oct 27;12(11). Epub 2020 Oct 27.

Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 6 Iroon Avenue, 2371 Agios Dhometios, Nicosia, Cyprus.

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http://dx.doi.org/10.3390/cancers12113140DOI Listing
October 2020

Stbd1 promotes glycogen clustering during endoplasmic reticulum stress and supports survival of mouse myoblasts.

J Cell Sci 2020 Oct 26;133(20). Epub 2020 Oct 26.

Department of Biochemical Genetics, The Cyprus Institute of Neurology and Genetics, P.O. Box 23462, 1683 Nicosia, Cyprus

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http://dx.doi.org/10.1242/jcs.244855DOI Listing
October 2020

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

Authors:
Laura Fachal Hugues Aschard Jonathan Beesley Daniel R Barnes Jamie Allen Siddhartha Kar Karen A Pooley Joe Dennis Kyriaki Michailidou Constance Turman Penny Soucy Audrey Lemaçon Michael Lush Jonathan P Tyrer Maya Ghoussaini Mahdi Moradi Marjaneh Xia Jiang Simona Agata Kristiina Aittomäki M Rosario Alonso Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Adalgeir Arason Volker Arndt Kristan J Aronson Banu K Arun Bernd Auber Paul L Auer Jacopo Azzollini Judith Balmaña Rosa B Barkardottir Daniel Barrowdale Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Katarzyna Białkowska Amie M Blanco Carl Blomqvist William Blot Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Ake Borg Kristin Bosse Hiltrud Brauch Hermann Brenner Ignacio Briceno Ian W Brock Angela Brooks-Wilson Thomas Brüning Barbara Burwinkel Saundra S Buys Qiuyin Cai Trinidad Caldés Maria A Caligo Nicola J Camp Ian Campbell Federico Canzian Jason S Carroll Brian D Carter Jose E Castelao Jocelyne Chiquette Hans Christiansen Wendy K Chung Kathleen B M Claes Christine L Clarke J Margriet Collée Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Cezary Cybulski Kamila Czene Mary B Daly Miguel de la Hoya Peter Devilee Orland Diez Yuan Chun Ding Gillian S Dite Susan M Domchek Thilo Dörk Isabel Dos-Santos-Silva Arnaud Droit Stéphane Dubois Martine Dumont Mercedes Duran Lorraine Durcan Miriam Dwek Diana M Eccles Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Olivia Fletcher Giuseppe Floris Henrik Flyger Lenka Foretova William D Foulkes Eitan Friedman Lin Fritschi Debra Frost Marike Gabrielson Manuela Gago-Dominguez Gaetana Gambino Patricia A Ganz Susan M Gapstur Judy Garber José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Maria Grazia Tibiletti Mark H Greene Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Patricia A Harrington Jaana M Hartikainen Mikael Hartman Wei He Catherine S Healey Bernadette A M Heemskerk-Gerritsen Jane Heyworth Peter Hillemanns Frans B L Hogervorst Antoinette Hollestelle Maartje J Hooning John L Hopper Anthony Howell Guanmengqian Huang Peter J Hulick Evgeny N Imyanitov Claudine Isaacs Motoki Iwasaki Agnes Jager Milena Jakimovska Anna Jakubowska Paul A James Ramunas Janavicius Rachel C Jankowitz Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Daehee Kang Pooja Middha Kapoor Beth Y Karlan Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Judy Kirk Cari M Kitahara Yon-Dschun Ko Irene Konstantopoulou Veli-Matti Kosma Stella Koutros Katerina Kubelka-Sabit Ava Kwong Kyriacos Kyriacou Yael Laitman Diether Lambrechts Eunjung Lee Goska Leslie Jenny Lester Fabienne Lesueur Annika Lindblom Wing-Yee Lo Jirong Long Artitaya Lophatananon Jennifer T Loud Jan Lubiński Robert J MacInnis Tom Maishman Enes Makalic Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin Maria Elena Martinez Keitaro Matsuo Tabea Maurer Dimitrios Mavroudis Rebecca Mayes Lesley McGuffog Catriona McLean Noura Mebirouk Alfons Meindl Austin Miller Nicola Miller Marco Montagna Fernando Moreno Kenneth Muir Anna Marie Mulligan Victor M Muñoz-Garzon Taru A Muranen Steven A Narod Rami Nassir Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Patrick Neven Finn C Nielsen Liene Nikitina-Zake Aaron Norman Kenneth Offit Edith Olah Olufunmilayo I Olopade Håkan Olsson Nick Orr Ana Osorio V Shane Pankratz Janos Papp Sue K Park Tjoung-Won Park-Simon Michael T Parsons James Paul Inge Sokilde Pedersen Bernard Peissel Beth Peshkin Paolo Peterlongo Julian Peto Dijana Plaseska-Karanfilska Karolina Prajzendanc Ross Prentice Nadege Presneau Darya Prokofyeva Miquel Angel Pujana Katri Pylkäs Paolo Radice Susan J Ramus Johanna Rantala Rohini Rau-Murthy Gad Rennert Harvey A Risch Mark Robson Atocha Romero Maria Rossing Emmanouil Saloustros Estela Sánchez-Herrero Dale P Sandler Marta Santamariña Christobel Saunders Elinor J Sawyer Maren T Scheuner Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Ben Schöttker Peter Schürmann Christopher Scott Rodney J Scott Leigha Senter Caroline M Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Xiao-Ou Shu Christian F Singer Thomas P Slavin Snezhana Smichkoska Melissa C Southey John J Spinelli Amanda B Spurdle Jennifer Stone Dominique Stoppa-Lyonnet Christian Sutter Anthony J Swerdlow Rulla M Tamimi Yen Yen Tan William J Tapper Jack A Taylor Manuel R Teixeira Maria Tengström Soo Hwang Teo Mary Beth Terry Alex Teulé Mads Thomassen Darcy L Thull Marc Tischkowitz Amanda E Toland Rob A E M Tollenaar Ian Tomlinson Diana Torres Gabriela Torres-Mejía Melissa A Troester Thérèse Truong Nadine Tung Maria Tzardi Hans-Ulrich Ulmer Celine M Vachon Christi J van Asperen Lizet E van der Kolk Elizabeth J van Rensburg Ana Vega Alessandra Viel Joseph Vijai Maartje J Vogel Qin Wang Barbara Wappenschmidt Clarice R Weinberg Jeffrey N Weitzel Camilla Wendt Hans Wildiers Robert Winqvist Alicja Wolk Anna H Wu Drakoulis Yannoukakos Yan Zhang Wei Zheng David Hunter Paul D P Pharoah Jenny Chang-Claude Montserrat García-Closas Marjanka K Schmidt Roger L Milne Vessela N Kristensen Juliet D French Stacey L Edwards Antonis C Antoniou Georgia Chenevix-Trench Jacques Simard Douglas F Easton Peter Kraft Alison M Dunning

Nat Genet 2020 01 7;52(1):56-73. Epub 2020 Jan 7.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41588-019-0537-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974400PMC
January 2020

Systemic Evaluation of Chimeric LNA/2'-O-Methyl Steric Blockers for Myotonic Dystrophy Type 1 Therapy.

Nucleic Acid Ther 2020 04 23;30(2):80-93. Epub 2019 Dec 23.

Department of Molecular Genetics, Function & Therapy, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1089/nat.2019.0811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133450PMC
April 2020

Evaluation of nipple aspirate fluid as a diagnostic tool for early detection of breast cancer.

Clin Proteomics 2018 11;15. Epub 2018 Jan 11.

1Institute of Cancer Therapeutics, University of Bradford, Bradford, UK.

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http://dx.doi.org/10.1186/s12014-017-9179-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763528PMC
January 2018

The effect of l-Arginine on Ciliary Beat Frequency in PCD patients, non-PCD respiratory patients and healthy controls.

Pulm Pharmacol Ther 2018 02 19;48:15-21. Epub 2017 Oct 19.

Medical School, University of Cyprus, Nicosia, Cyprus; Hospital 'Archbishop Makarios III', Nicosia, Cyprus. Electronic address:

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http://dx.doi.org/10.1016/j.pupt.2017.10.010DOI Listing
February 2018

Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.

Proteomics Clin Appl 2017 09 26;11(9-10). Epub 2017 Jun 26.

Institute of Cancer Therapeutics, University of Bradford, Bradford, UK.

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http://dx.doi.org/10.1002/prca.201700015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638085PMC
September 2017

Mouse Stbd1 is -myristoylated and affects ER-mitochondria association and mitochondrial morphology.

J Cell Sci 2017 03 30;130(5):903-915. Epub 2017 Jan 30.

Department of Biochemical Genetics, The Cyprus Institute of Neurology and Genetics, P. O. Box 23462, Nicosia 1683, Cyprus

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http://dx.doi.org/10.1242/jcs.195263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358331PMC
March 2017

Prevalence of primary ciliary dyskinesia in consecutive referrals of suspect cases and the transmission electron microscopy detection rate: a systematic review and meta-analysis.

Pediatr Res 2017 03 9;81(3):398-405. Epub 2016 Dec 9.

Cyprus International Institute for Environmental & Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus.

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http://dx.doi.org/10.1038/pr.2016.263DOI Listing
March 2017

Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review.

J Cell Mol Med 2017 05 23;21(5):993-1012. Epub 2016 Nov 23.

Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1111/jcmm.13031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387176PMC
May 2017

Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.

Mol Nutr Food Res 2017 04 25;61(4). Epub 2017 Jan 25.

Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1002/mnfr.201600558DOI Listing
April 2017

Fanconi anemia-D1 due to homozygosity for the BRCA2 gene Cypriot founder mutation: A case report.

Oncol Lett 2016 Jan 2;11(1):471-473. Epub 2015 Nov 2.

Cyprus School of Molecular Medicine, Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus; Department of Clinical Genetics, Makarios Medical Centre and Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.

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http://dx.doi.org/10.3892/ol.2015.3852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727152PMC
January 2016

The synergistic effect between the Mediterranean diet and GSTP1 or NAT2 SNPs decreases breast cancer risk in Greek-Cypriot women.

Eur J Nutr 2017 Mar 16;56(2):545-555. Epub 2015 Nov 16.

Department of EM/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 6 International Airport Avenue, 2370, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s00394-015-1099-3DOI Listing
March 2017

MnSOD and CAT polymorphisms modulate the effect of the Mediterranean diet on breast cancer risk among Greek-Cypriot women.

Eur J Nutr 2016 Jun 1;55(4):1535-44. Epub 2015 Jul 1.

Department of EM/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 6 International Airport Avenue, 2370, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s00394-015-0971-5DOI Listing
June 2016

Oxaliplatin-induced neurotoxicity is mediated through gap junction channels and hemichannels and can be prevented by octanol.

Neuropharmacology 2015 Oct 1;97:289-305. Epub 2015 Jun 1.

Neuroscience Laboratory, The Cyprus Institute of Neurology and Genetics, Cyprus School of Molecular Medicine, Nicosia, Cyprus; Neurology Clinics, The Cyprus Institute of Neurology and Genetics, Cyprus School of Molecular Medicine, Nicosia, Cyprus. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.05.021DOI Listing
October 2015

Clinical features of primary ciliary dyskinesia in Cyprus with emphasis on lobectomized patients.

Respir Med 2015 Mar 31;109(3):347-56. Epub 2015 Jan 31.

Department of Electron Microscopy and Molecular Pathology, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus; Cyprus School of Molecular Medicine, Nicosia, Cyprus. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2015.01.015DOI Listing
March 2015

Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation.

Eur J Clin Invest 2015 Mar;45(3):303-32

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; Department of Electron Microscopy / Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1111/eci.12406DOI Listing
March 2015

The role of ubiquitin-binding domains in human pathophysiology.

Crit Rev Clin Lab Sci 2014 Oct 5;51(5):280-90. Epub 2014 Jun 5.

The Cyprus Institute of Neurology and Genetics , Nicosia , Cyprus .

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http://dx.doi.org/10.3109/10408363.2014.915287DOI Listing
October 2014

The bifacial role of helminths in cancer: involvement of immune and non-immune mechanisms.

Crit Rev Clin Lab Sci 2014 Jun 4;51(3):138-48. Epub 2014 Mar 4.

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital , Toronto, Ontario , Canada .

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http://dx.doi.org/10.3109/10408363.2014.886180DOI Listing
June 2014

Identification of stage-specific breast markers using quantitative proteomics.

J Proteome Res 2013 Dec 29;12(12):5696-708. Epub 2013 Oct 29.

Institute of Cancer Therapeutics, University of Bradford , Tumbling Hill Street, Bradford BD7 1DP, United Kingdom.

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http://dx.doi.org/10.1021/pr400662kDOI Listing
December 2013

Infection and cancer: revaluation of the hygiene hypothesis.

Clin Cancer Res 2013 Jun 27;19(11):2834-41. Epub 2013 Mar 27.

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://clincancerres.aacrjournals.org/content/early/2013/05/
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http://clincancerres.aacrjournals.org/content/early/2013/03/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-3661DOI Listing
June 2013

BRCA1 and Its Network of Interacting Partners.

Biology (Basel) 2013 Jan 2;2(1):40-63. Epub 2013 Jan 2.

Department of Electron Microscopy/Molecular Pathology, Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, 6 International Airport Avenue, P.O. Box 23462, 1683 Nicosia, Cyprus.

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http://dx.doi.org/10.3390/biology2010040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009870PMC
January 2013

Proteomic profiling of breast tissue collagens and site-specific characterization of hydroxyproline residues of collagen alpha-1-(I).

J Proteome Res 2012 Dec 14;11(12):5890-902. Epub 2012 Nov 14.

Koichi Tanaka Research Laboratory, Shimadzu Corporation, Manchester, United Kingdom.

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http://dx.doi.org/10.1021/pr300656rDOI Listing
December 2012

Replication of genome-wide discovered breast cancer risk loci in the Cypriot population.

Breast Cancer Res Treat 2011 Jul 6;128(1):267-72. Epub 2011 Jan 6.

Department of Electron Microscope / Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Ayios Dometios, 23462, 1683, Nicosia, Cyprus.

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http://link.springer.com/10.1007/s10549-010-1319-8
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http://dx.doi.org/10.1007/s10549-010-1319-8DOI Listing
July 2011

The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS.

J Neurosci 2010 Oct;30(42):13943-54

Department of Basic Science, Faculty of Medicine, University of Crete and Institute of Molecular Biology and Biotechnology-Foundation for Research and Technology, 71110, Heraklion, Crete, Greece.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2574-10.2
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http://dx.doi.org/10.1523/JNEUROSCI.2574-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634759PMC
October 2010

Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy.

J Neuropathol Exp Neurol 2010 Sep;69(9):945-58

Neuroscience Laboratory and Neurology Clinics, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1097/NEN.0b013e3181efa658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034224PMC
September 2010

Quantitative proteomic profiling of matched normal and tumor breast tissues.

J Proteome Res 2010 Aug;9(8):3891-902

Institute of Cancer Therapeutics, University of Bradford, West Yorkshire, United Kingdom.

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http://pubs.acs.org/doi/abs/10.1021/pr100113a
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http://dx.doi.org/10.1021/pr100113aDOI Listing
August 2010

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population.

Breast Cancer Res Treat 2010 May 28;121(1):147-56. Epub 2009 Aug 28.

Department of Electron Microscope/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s10549-009-0518-7DOI Listing
May 2010

DNA-repair genetic polymorphisms and risk of breast cancer in Cyprus.

Breast Cancer Res Treat 2009 Jun 16;115(3):623-7. Epub 2008 Jun 16.

Department of Electron Microscope/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 6, International Airport Ave., Ayios Dometios, P.O. Box 23462, 1683, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s10549-008-0084-4DOI Listing
June 2009

Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk of breast cancer in Cyprus.

Breast Cancer Res Treat 2008 Dec 10;112(3):575-9. Epub 2008 Jan 10.

Department of Electron Microscope/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Ayios Dometios, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s10549-007-9881-4DOI Listing
December 2008

Formation mechanism of nanotubes comprising layers of PbS nanoparticles in polymer-surfactant solutions.

J Colloid Interface Sci 2006 Oct 29;302(1):170-7. Epub 2006 Jun 29.

Department of Chemistry, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus.

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http://linkinghub.elsevier.com/retrieve/pii/S002197970600536
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http://dx.doi.org/10.1016/j.jcis.2006.06.036DOI Listing
October 2006

Study of copper sulfide crystallization in PEO-SDS solutions.

Langmuir 2004 Jun;20(13):5605-12

Department of Chemistry, University of Cyprus, PO Box 20537, 1678 Nicosia, Cyprus.

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http://dx.doi.org/10.1021/la036372dDOI Listing
June 2004

Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease.

Muscle Nerve 2005 Feb;31(2):260-5

Department of Clinical Neurosciences, Cyprus Institute of Neurology and Genetics, P.O. Box 23462, Nicosia, Cyprus.

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http://dx.doi.org/10.1002/mus.20144DOI Listing
February 2005

Hereditary breast and ovarian cancer in Cyprus: identification of a founder BRCA2 mutation.

Cancer Genet Cytogenet 2004 Jun;151(2):152-6

Department of Electron Microscopy and Molecular Pathology, The Cyprus Institute of Neurology and Genetics, POB 23462, 1683 Nicosia, Cyprus.

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http://linkinghub.elsevier.com/retrieve/pii/S016546080300434
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http://dx.doi.org/10.1016/j.cancergencyto.2003.09.020DOI Listing
June 2004

BRCA2 germline mutations in Cypriot patients with familial breast/ovarian cancer.

Hum Mutat 2003 Feb;21(2):171

Department of Electron Microscopy and Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1002/humu.9110DOI Listing
February 2003

Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family.

Oncol Rep 2002 Mar-Apr;9(2):383-6

Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 1683 Nicosia, Cyprus.

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May 2002