Kyoung-Jin Min

Kyoung-Jin Min

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Kyoung-Jin Min

Publications by authors named "Kyoung-Jin Min"

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Oridonin enhances TRAIL-induced apoptosis through GALNT14-mediated DR5 glycosylation.

Biochimie 2019 Oct 20;165:108-114. Epub 2019 Jul 20.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu, 42601, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2019.07.015DOI Listing
October 2019

Hispidulin Inhibits Mast Cell-Mediated Allergic Inflammation through Down-Regulation of Histamine Release and Inflammatory Cytokines.

Molecules 2019 Jun 5;24(11). Epub 2019 Jun 5.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu 42601, Korea.

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http://dx.doi.org/10.3390/molecules24112131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600596PMC
June 2019

Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species.

Antioxid Redox Signal 2019 May 30;30(14):1731-1745. Epub 2018 Oct 30.

1 KNU-Center for Nonlinear Dynamics, CMRI, School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University , Daegu, South Korea .

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http://dx.doi.org/10.1089/ars.2018.7507DOI Listing
May 2019

WP1130 Enhances TRAIL-Induced Apoptosis through USP9X-Dependent miR-708-Mediated Downregulation of c-FLIP.

Cancers (Basel) 2019 Mar 11;11(3). Epub 2019 Mar 11.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu 42601, Korea.

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http://dx.doi.org/10.3390/cancers11030344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469024PMC
March 2019

Elucidation for modulation of death receptor (DR) 5 to strengthen apoptotic signals in cancer cells.

Arch Pharm Res 2019 Jan 10;42(1):88-100. Epub 2019 Jan 10.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, Korea.

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http://dx.doi.org/10.1007/s12272-018-01103-yDOI Listing
January 2019

BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression.

Cell Death Discov 2018 Dec 20;4:29. Epub 2018 Feb 20.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu 42601 South Korea.

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http://dx.doi.org/10.1038/s41420-018-0035-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841352PMC
December 2018

Maritoclax Enhances TRAIL-Induced Apoptosis via CHOP-Mediated Upregulation of DR5 and miR-708-Mediated Downregulation of cFLIP.

Molecules 2018 Nov 20;23(11). Epub 2018 Nov 20.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Korea.

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http://dx.doi.org/10.3390/molecules23113030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278439PMC
November 2018

HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis.

Molecules 2018 Oct 24;23(11). Epub 2018 Oct 24.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Korea.

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http://dx.doi.org/10.3390/molecules23112755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278488PMC
October 2018

Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells.

Int J Mol Sci 2018 Oct 22;19(10). Epub 2018 Oct 22.

Department of Immunology, School of Medicine, Keimyung University, Daegu 42601, Korea.

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http://dx.doi.org/10.3390/ijms19103280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214104PMC
October 2018

mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy.

Oncogene 2018 09 30;37(38):5205-5220. Epub 2018 May 30.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea.

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http://dx.doi.org/10.1038/s41388-018-0345-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147804PMC
September 2018

Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells.

Molecules 2018 Sep 5;23(9). Epub 2018 Sep 5.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu 42601, Korea.

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http://dx.doi.org/10.3390/molecules23092264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225471PMC
September 2018

Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression.

Molecules 2018 Jul 2;23(7). Epub 2018 Jul 2.

Department of Immunology and School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 42601, Korea.

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http://dx.doi.org/10.3390/molecules23071614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099973PMC
July 2018

Differential expression patterns of the short and long isoform of cFLIP on FasL‑mediated apoptosis.

Oncol Rep 2018 May 16;39(5):2443-2449. Epub 2018 Mar 16.

Department of Immunology, School of Medicine, Keimyung University, Dalseo‑gu, Daegu 704‑701, Republic of Korea.

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http://dx.doi.org/10.3892/or.2018.6317DOI Listing
May 2018

Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression.

Biochem Biophys Res Commun 2018 04 13;498(4):849-854. Epub 2018 Mar 13.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.03.068DOI Listing
April 2018

Angelicin potentiates TRAIL-induced apoptosis in renal carcinoma Caki cells through activation of caspase 3 and down-regulation of c-FLIP expression.

Drug Dev Res 2018 02 16;79(1):3-10. Epub 2017 Oct 16.

Department of Immunology and School of Medicine, Keimyung University, Dalseo-Gu, Daegu, South Korea.

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http://dx.doi.org/10.1002/ddr.21414DOI Listing
February 2018

Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin.

Oncotarget 2017 Dec 20;8(63):106672-106684. Epub 2017 Nov 20.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.18632/oncotarget.22508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739765PMC
December 2017

RIP1-dependent reactive oxygen species production executes artesunate-induced cell death in renal carcinoma Caki cells.

Mol Cell Biochem 2017 Nov 2;435(1-2):15-24. Epub 2017 May 2.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea.

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http://dx.doi.org/10.1007/s11010-017-3052-7DOI Listing
November 2017

Volasertib Enhances Sensitivity to TRAIL in Renal Carcinoma Caki Cells through Downregulation of c-FLIP Expression.

Int J Mol Sci 2017 Nov 29;18(12). Epub 2017 Nov 29.

Department of Immunology, School of Mediine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Korea.

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http://dx.doi.org/10.3390/ijms18122568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751171PMC
November 2017

NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin.

Redox Biol 2017 10 9;13:608-622. Epub 2017 Aug 9.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554966PMC
October 2017

The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression.

Oncotarget 2017 Oct 24;8(47):83195-83206. Epub 2017 Aug 24.

Department of Immunology, School of Medicine, Keimyung University, Daegu 704-701, South Korea.

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http://dx.doi.org/10.18632/oncotarget.20541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669960PMC
October 2017

Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP.

Antioxid Redox Signal 2017 08 9;27(4):215-233. Epub 2017 Jan 9.

1 Department of Immunology, School of Medicine, Keimyung University , Daegu, South Korea .

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http://dx.doi.org/10.1089/ars.2016.6749DOI Listing
August 2017

Fisetin Induces Apoptosis Through p53-Mediated Up-Regulation of DR5 Expression in Human Renal Carcinoma Caki Cells.

Molecules 2017 Aug 2;22(8). Epub 2017 Aug 2.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Korea.

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http://dx.doi.org/10.3390/molecules22081285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151974PMC
August 2017

Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels.

Sci Rep 2017 08 21;7(1):8874. Epub 2017 Aug 21.

KNU-Center for Nonlinear Dynamics, School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea.

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http://dx.doi.org/10.1038/s41598-017-09262-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567039PMC
August 2017

YM155 enhances ABT-737-mediated apoptosis through Mcl-1 downregulation in Mcl-1-overexpressed cancer cells.

Mol Cell Biochem 2017 May 24;429(1-2):91-102. Epub 2017 Jan 24.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea.

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http://dx.doi.org/10.1007/s11010-016-2938-0DOI Listing
May 2017

Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells.

Oncol Rep 2017 Apr 6;37(4):2348-2354. Epub 2017 Mar 6.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.3892/or.2017.5490DOI Listing
April 2017

Thymoquinone induces apoptosis through downregulation of c-FLIP and Bcl-2 in renal carcinoma Caki cells.

Oncol Rep 2016 Oct 12;36(4):2261-7. Epub 2016 Aug 12.

Department of Immunology, School of Medicine, Keimyung University, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.3892/or.2016.5019DOI Listing
October 2016

Carnosic acid attenuates unilateral ureteral obstruction-induced kidney fibrosis via inhibition of Akt-mediated Nox4 expression.

Free Radic Biol Med 2016 08 20;97:50-57. Epub 2016 May 20.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.05.020DOI Listing
August 2016

Rottlerin induces cyclooxygenase-2 upregulation through an ATF4 and reactive oxygen species-independent pathway in HEI-OC1 cells.

Mol Med Rep 2016 Jul 20;14(1):845-50. Epub 2016 May 20.

Department of Immunology, School of Medicine, Keimyung University, Daegu 700712, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2016.5320DOI Listing
July 2016

Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells.

Sci Rep 2016 Mar 11;6:22921. Epub 2016 Mar 11.

Department of Immunology, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1038/srep22921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786792PMC
March 2016

RU486 Induces Pro-Apoptotic Endoplasmic Reticulum Stress Through the Induction of CHOP Expression by Enhancing C/EBPδ Expression in Human Renal Carcinoma Caki Cells.

J Cell Biochem 2016 Feb;117(2):361-9

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea.

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http://doi.wiley.com/10.1002/jcb.25278
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http://dx.doi.org/10.1002/jcb.25278DOI Listing
February 2016

Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells.

Sci Rep 2016 Jan 4;6:18642. Epub 2016 Jan 4.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1038/srep18642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698673PMC
January 2016

FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells.

Oncotarget 2015 May;6(13):11614-26

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu 704-701, South Korea.

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http://www.oncotarget.com/fulltext/3426
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484480PMC
http://dx.doi.org/10.18632/oncotarget.3426DOI Listing
May 2015

Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells.

J Pineal Res 2015 Apr 9;58(3):310-20. Epub 2015 Mar 9.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, South Korea.

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http://doi.wiley.com/10.1111/jpi.12217
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http://dx.doi.org/10.1111/jpi.12217DOI Listing
April 2015

Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways.

Mol Carcinog 2015 Mar 11;54(3):216-28. Epub 2013 Oct 11.

Department of Immunology, School of Medicine, Keimyung University, Daegu, South Korea.

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http://doi.wiley.com/10.1002/mc.22092
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http://dx.doi.org/10.1002/mc.22092DOI Listing
March 2015

Combined treatment with ABT-737 and VX-680 induces apoptosis in Bcl-2- and c-FLIP-overexpressing breast carcinoma cells.

Oncol Rep 2015 Mar 15;33(3):1395-401. Epub 2015 Jan 15.

Department of Immunology, Keimyung University, School of Medicine, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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https://www.spandidos-publications.com/10.3892/or.2015.3728
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http://dx.doi.org/10.3892/or.2015.3728DOI Listing
March 2015

6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression.

Chem Biol Interact 2015 Feb 22;228:69-78. Epub 2015 Jan 22.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2015.01.020DOI Listing
February 2015

Withaferin A induces apoptosis through the generation of thiol oxidation in human head and neck cancer cells.

Int J Mol Med 2015 Jan 27;35(1):247-52. Epub 2014 Oct 27.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.3892/ijmm.2014.1983DOI Listing
January 2015

Axl is a novel target of withaferin A in the induction of apoptosis and the suppression of invasion.

Biochem Biophys Res Commun 2014 Aug 9;451(3):455-60. Epub 2014 Aug 9.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.08.018DOI Listing
August 2014

Dicoumarol sensitizes renal cell carcinoma Caki cells to TRAIL-induced apoptosis through down-regulation of Bcl-2, Mcl-1 and c-FLIP in a NQO1-independent manner.

Exp Cell Res 2014 Apr 22;323(1):144-54. Epub 2014 Jan 22.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.01.009DOI Listing
April 2014

Astrogliosis is a possible player in preventing delayed neuronal death.

Mol Cells 2014 Apr 22;37(4):345-55. Epub 2014 Apr 22.

Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, Suwon 442-721, Korea.

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http://www.e-sciencecentral.org/upload/molcell/pdf/molcell-3
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http://www.molcells.org/journal/view.html?doi=10.14348/molce
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http://dx.doi.org/10.14348/molcells.2014.0046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012084PMC
April 2014

Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation.

Chem Biol Interact 2014 Mar 16;211:36-43. Epub 2014 Jan 16.

Department of Immunology, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.01.004DOI Listing
March 2014

Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate.

Integr Med Res 2014 Mar 9;3(1):16-24. Epub 2013 Dec 9.

Department of Immunology, School of Medicine, Keimyung University, Daegu, Korea.

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http://dx.doi.org/10.1016/j.imr.2013.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481703PMC
March 2014

Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells.

J Pineal Res 2014 Jan 8;56(1):97-106. Epub 2013 Nov 8.

Department of Immunology, School of Medicine, Keimyung University, Daegu, Korea.

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http://doi.wiley.com/10.1111/jpi.12102
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http://dx.doi.org/10.1111/jpi.12102DOI Listing
January 2014

Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation.

Food Chem Toxicol 2013 Aug 16;58:77-85. Epub 2013 Apr 16.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.fct.2013.04.008DOI Listing
August 2013

RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK.

Oncol Rep 2013 Jul 26;30(1):506-12. Epub 2013 Apr 26.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, Republic of Korea.

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http://dx.doi.org/10.3892/or.2013.2432DOI Listing
July 2013

Anisomycin treatment enhances TRAIL-mediated apoptosis in renal carcinoma cells through the down-regulation of Bcl-2, c-FLIP(L) and Mcl-1.

Biochimie 2013 Apr 20;95(4):858-65. Epub 2012 Dec 20.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S03009084120047
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http://dx.doi.org/10.1016/j.biochi.2012.12.002DOI Listing
April 2013

Helenalin-induced apoptosis is dependent on production of reactive oxygen species and independent of induction of endoplasmic reticulum stress in renal cell carcinoma.

Toxicol In Vitro 2013 Mar 30;27(2):588-96. Epub 2012 Oct 30.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.tiv.2012.10.014DOI Listing
March 2013

Calyculin A causes sensitization to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by ROS-mediated down-regulation of cellular FLICE-inhibiting protein (c-FLIP) and by enhancing death receptor 4 mRNA stabilization.

Apoptosis 2012 Nov;17(11):1223-34

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1007/s10495-012-0753-yDOI Listing
November 2012

Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells.

Biochem Biophys Res Commun 2012 Oct 12;427(1):24-9. Epub 2012 Sep 12.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.bbrc.2012.08.133DOI Listing
October 2012

Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells.

J Pineal Res 2012 Aug 31;53(1):99-106. Epub 2012 Jan 31.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, Korea.

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http://doi.wiley.com/10.1111/j.1600-079X.2012.00975.x
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http://dx.doi.org/10.1111/j.1600-079X.2012.00975.xDOI Listing
August 2012

Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models.

Toxicol Appl Pharmacol 2012 Jul 27;262(1):91-8. Epub 2012 Apr 27.

College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 702-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.taap.2012.04.025DOI Listing
July 2012

The effect of oxidized low density lipoprotein (oxLDL)-induced heme oxygenase-1 on LPS-induced inflammation in RAW 264.7 macrophage cells.

Cell Signal 2012 Jun 10;24(6):1215-21. Epub 2012 Feb 10.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.cellsig.2012.02.001DOI Listing
June 2012

Anti-inflammatory activity of hydroxycinnamic acid derivatives isolated from corn bran in lipopolysaccharide-stimulated Raw 264.7 macrophages.

Food Chem Toxicol 2012 May 17;50(5):1309-16. Epub 2012 Feb 17.

Department of Food Science and Nutrition, Catholic University of Daegu, Gyeongsan 712-702, Republic of Korea.

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http://dx.doi.org/10.1016/j.fct.2012.02.011DOI Listing
May 2012

High-mobility group box-1 protein induces mucin 8 expression through the activation of the JNK and PI3K/Akt signal pathways in human airway epithelial cells.

Biochem Biophys Res Commun 2012 May 13;421(3):436-41. Epub 2012 Apr 13.

Department of Otolaryngology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2012.03.131DOI Listing
May 2012

Spatial and temporal correlation in progressive degeneration of neurons and astrocytes in contusion-induced spinal cord injury.

J Neuroinflammation 2012 May 25;9:100. Epub 2012 May 25.

Department of Pharmacology, Ajou University School of Medicine, san-5 Woncheon-dong Youngtong-gu, Suwon, Kyunggi-do, 442-721, Korea.

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http://dx.doi.org/10.1186/1742-2094-9-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418552PMC
May 2012

Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity.

J Pineal Res 2012 Apr 8;52(3):296-304. Epub 2012 Jan 8.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, South Korea.

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http://doi.wiley.com/10.1111/j.1600-079X.2011.00943.x
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http://dx.doi.org/10.1111/j.1600-079X.2011.00943.xDOI Listing
April 2012

Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism.

Chem Biol Interact 2012 Apr 5;197(1):1-7. Epub 2012 Mar 5.

Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, Republic of Korea.

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http://dx.doi.org/10.1016/j.cbi.2012.02.003DOI Listing
April 2012

Glucocorticoid receptor antagonist sensitizes TRAIL-induced apoptosis in renal carcinoma cells through up-regulation of DR5 and down-regulation of c-FLIP(L) and Bcl-2.

J Mol Med (Berl) 2012 Mar 19;90(3):309-19. Epub 2011 Oct 19.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://link.springer.com/content/pdf/10.1007/s00109-011-0821
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http://link.springer.com/10.1007/s00109-011-0821-8
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http://dx.doi.org/10.1007/s00109-011-0821-8DOI Listing
March 2012

An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-κB-independent mechanism.

Cell Signal 2011 Sep 18;23(9):1505-13. Epub 2011 May 18.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.cellsig.2011.05.013DOI Listing
September 2011

Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells.

Int Immunopharmacol 2011 Aug 21;11(8):1137-42. Epub 2011 Mar 21.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.intimp.2011.02.029DOI Listing
August 2011

Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells.

Toxicol In Vitro 2011 Apr 23;25(3):692-8. Epub 2011 Jan 23.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, South Korea.

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http://dx.doi.org/10.1016/j.tiv.2011.01.010DOI Listing
April 2011

Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.

Chem Biol Interact 2011 Apr 18;190(2-3):102-8. Epub 2011 Feb 18.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.cbi.2011.02.013DOI Listing
April 2011

Astrocytes in injury states rapidly produce anti-inflammatory factors and attenuate microglial inflammatory responses.

J Neurochem 2010 Dec 12;115(5):1161-71. Epub 2010 Oct 12.

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon, Korea Brain Disease Research Center, Ajou University School of Medicine, Suwon, Korea.

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http://doi.wiley.com/10.1111/j.1471-4159.2010.07004.x
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http://dx.doi.org/10.1111/j.1471-4159.2010.07004.xDOI Listing
December 2010

Enhanced phosphatidylinositol 4-phosphate 5-kinase alpha expression and PI(4,5)P2 production in LPS-stimulated microglia.

Neurochem Int 2010 Nov 24;57(5):600-7. Epub 2010 Jul 24.

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon, Gyeonggi, Republic of Korea.

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http://dx.doi.org/10.1016/j.neuint.2010.07.008DOI Listing
November 2010

Adenosine induces hemeoxygenase-1 expression in microglia through the activation of phosphatidylinositol 3-kinase and nuclear factor E2-related factor 2.

Glia 2008 Jul;56(9):1028-37

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon, 442-721, Korea.

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http://dx.doi.org/10.1002/glia.20676DOI Listing
July 2008

Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain.

Glia 2007 Nov;55(15):1577-88

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon, Korea.

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http://dx.doi.org/10.1002/glia.20571DOI Listing
November 2007

Multiple mechanisms that prevent excessive brain inflammation.

J Neurosci Res 2007 Aug;85(11):2298-305

Department of Pharmacology, Ajou University School of Medicine, Suwon, Kyunggi-do, Korea.

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http://dx.doi.org/10.1002/jnr.21254DOI Listing
August 2007

Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation.

J Neurosci 2006 Feb;26(6):1880-7

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon 442-721, Korea.

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http://dx.doi.org/10.1523/JNEUROSCI.3696-05.2006DOI Listing
February 2006

Anti-inflammatory roles of retinoic acid in rat brain astrocytes: Suppression of interferon-gamma-induced JAK/STAT phosphorylation.

Biochem Biophys Res Commun 2005 Apr;329(1):125-31

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon 442-721, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2005.01.110DOI Listing
April 2005

Gangliosides activate microglia via protein kinase C and NADPH oxidase.

Glia 2004 Nov;48(3):197-206

Neuroscience Graduate Program, Ajou University School of Medicine, Suwon, Korea.

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http://dx.doi.org/10.1002/glia.20069DOI Listing
November 2004

Protein kinase A mediates microglial activation induced by plasminogen and gangliosides.

Exp Mol Med 2004 Oct;36(5):461-7

Department of Pharmacology, Ajou University, School of Medicine, Suwon 442-721, Korea.

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http://dx.doi.org/10.1038/emm.2004.58DOI Listing
October 2004

Phospholipase D isozymes mediate epigallocatechin gallate-induced cyclooxygenase-2 expression in astrocyte cells.

J Biol Chem 2004 Sep 21;279(37):38125-33. Epub 2004 Jun 21.

Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M402085200
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September 2004

Thrombin induces suppressor of cytokine signaling 3 expression in brain microglia via protein kinase Cdelta activation.

Biochem Biophys Res Commun 2004 May;317(3):811-6

Neuroscience graduate program, Ajou University School of Medicine, Suwon 442-721, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.118DOI Listing
May 2004

Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species.

Biochem Biophys Res Commun 2003 Dec;312(4):969-74

Neuroscience Graduate Program, Ajou University School of Medicine, 442-721, Suwon, South Korea

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http://dx.doi.org/10.1016/j.bbrc.2003.11.010DOI Listing
December 2003

Prothrombin kringle-2 activates cultured rat brain microglia.

J Immunol 2002 Jun;168(11):5805-10

Department of Pharmacology, Neuroscience Graduate Program, and Brain Disease Research Center, Ajou University School of Medicine, Suwon, Korea.

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http://dx.doi.org/10.4049/jimmunol.168.11.5805DOI Listing
June 2002