Kyoung Yong Jeong, PhD - Yonsei University College of Medicine

Kyoung Yong Jeong

PhD

Yonsei University College of Medicine

Seoul | Korea, Republic of

Main Specialties: Allergy & Immunology

Additional Specialties: Allergen

ORCID logohttps://orcid.org/0000-0001-9887-1426

Kyoung Yong Jeong, PhD - Yonsei University College of Medicine

Kyoung Yong Jeong

PhD

Introduction

Primary Affiliation: Yonsei University College of Medicine - Seoul , Korea, Republic of

Specialties:

Additional Specialties:

Education

Mar 2001 - Feb 2004
Yonsei University College of Medicine
PhD
Medical Science

Publications

77Publications

1223Reads

195Profile Views

5PubMed Central Citations

Optimal conditions for the storage of German cockroach extract.

Mol Med Rep 2020 Feb 27;21(2):953-958. Epub 2019 Nov 27.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2019.10854DOI Listing
February 2020
1.484 Impact Factor

Stability of extracts from pollens of allergenic importance in Korea.

Korean J Intern Med 2020 01 20;35(1):222-230. Epub 2019 Sep 20.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3904/kjim.2018.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960046PMC
January 2020
3 Reads

Insect Allergens on the Dining Table.

Curr Protein Pept Sci 2020 ;21(2):159-169

Department of Internal Medicine, Institute of Allergy, Yonsei University, College of Medicine, Seoul 03722, Korea.

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http://dx.doi.org/10.2174/1389203720666190715091951DOI Listing
January 2020
3.154 Impact Factor

Soluble CD93 in allergic asthma.

Sci Rep 2020 01 15;10(1):323. Epub 2020 Jan 15.

Institute of Allergy, Yonsei University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-019-57176-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962376PMC
January 2020
5.078 Impact Factor

Survey of IgE Reactivity to Nonbiting Midges in Korea and Identification of IgE-Binding Protein.

Allergy Asthma Immunol Res 2019 Sep;11(5):644-654

Department of Environmental Medical Biology, Arthropods of Medical Importance Resource Bank, Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2019.11.5.644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658401PMC
September 2019
1 Read
3.084 Impact Factor

Allergen-specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model.

Allergy 2018 Sep 16;73(9):1801-1811. Epub 2018 May 16.

Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/all.13465DOI Listing
September 2018
23 Reads
6.028 Impact Factor

IgE Cross-Reactivity between Humulus japonicus and Humulus lupulus.

Yonsei Med J 2018 Sep;59(7):852-856

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2018.59.7.852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082984PMC
September 2018
3 Reads
1.263 Impact Factor

Sensitization to various minor house dust mite allergens is greater in patients with atopic dermatitis than in those with respiratory allergic disease.

Clin Exp Allergy 2018 08 11;48(8):1050-1058. Epub 2018 Jun 11.

Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/cea.13164DOI Listing
August 2018
10 Reads
4.769 Impact Factor

Allergen standardization

Allergy Asthma Respir Dis

Allergen immunotherapy (AIT) and diagnostic tests are based on well qualified allergen extracts, which are derived from biologic organisms. The allergenicity of the extracts is markedly affected by the climate, soil, year of production, storage methods, and manufacturing processes. Thus, standardization is a crucial process to guarantee the clinical efficacy and safety of the treatment and diagnostic reagents in allergic diseases. There are 2 different standardization processes, one is In vivo and the other is in vitro standardization. In vivo standardization is done by skin prick or intradermal tests. For in vitro standardization, measurements of weight/volume and protein nitrogen units have been widely used since the early period of AIT. In the 1970s, immunological methods such as radial immunodiffusion, enzyme-linked immunosorbent assay (ELISA) inhibition test and basophil activation test were developed. Allergen potency measured by ELISA inhibition test reflects the potency measured by skin tests and has been widely used for quality control of batch-to-batch variation. Recently, standardizations focused on the major allergen content of extracts have developed. Standardization for major allergens requires reliable reference materials (RMs) made of recombinant allergens and 2-site ELISA kits. However, only a few reliable RM and 2-site ELISA kits are available. For the standardization process, allergen RMs are essential. The Center for Biologics Evaluation and Research of the U.S. Food and Drug Administration provides 19 allergen RMs, and our research team also proved 9 RMs which are important in Korea. In conclusion, allergen standardization is an essential process for the development of reliable treatment and diagnostic reagents, and allergy specialist should be familiar with the concept of allergen standardization.

https://www.koreamed.org/article/0206AARD/2018.6.4.191

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July 2018
2 Reads

Effects of the Th2-dominant milieu on allergic responses in Der f 1-activated mouse basophils and mast cells.

Sci Rep 2018 05 16;8(1):7706. Epub 2018 May 16.

Department of Environmental Medical Biology, Arthropods of Medical Importance Resource Bank, Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, 03722, Korea.

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http://dx.doi.org/10.1038/s41598-018-25741-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955989PMC
May 2018
41 Reads
5.080 Impact Factor

Comparison between Newly Developed and Commercial Inhalant Skin Prick Test Reagents Using In Vivo and In Vitro Methods.

J Korean Med Sci 2018 Mar 26;33(13):e101. Epub 2018 Mar 26.

Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3346/jkms.2018.33.e101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865053PMC
March 2018
22 Reads
1.253 Impact Factor

Successful transdermal allergen delivery and allergen-specific immunotherapy using biodegradable microneedle patches.

Biomaterials 2018 Jan 4;150:38-48. Epub 2017 Oct 4.

Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, South Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.10.013DOI Listing
January 2018
29 Reads
8.557 Impact Factor

Characterization of a Major Allergen from Mongolian Oak, Quercus mongolica, a Dominant Species of Oak in Korea.

Int Arch Allergy Immunol 2017 25;174(2):77-85. Epub 2017 Oct 25.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000481092DOI Listing
December 2017
96 Reads
2.673 Impact Factor

Accurate assessment of alpha-gal syndrome using cetuximab and bovine thyroglobulin-specific IgE.

Mol Nutr Food Res 2017 10 3;61(10). Epub 2017 Jul 3.

Division of Allergy and Immunology, Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/mnfr.201601046DOI Listing
October 2017
75 Reads
4.603 Impact Factor

Monoclonal Antibodies to Recombinant Fag e 3 Buckwheat Allergen and Development of a Two-site ELISA for Its Quantification.

Allergy Asthma Immunol Res 2017 Sep;9(5):417-422

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2017.9.5.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500696PMC
September 2017
49 Reads
3.084 Impact Factor

Role of tropomyosin in silkworm allergy.

Mol Med Rep 2017 May 24;15(5):3264-3270. Epub 2017 Mar 24.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2017.6373DOI Listing
May 2017
20 Reads
1.484 Impact Factor

Soluble CD93 in Serum as a Marker of Allergic Inflammation.

Yonsei Med J 2017 May;58(3):598-603

Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2017.58.3.598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368146PMC
May 2017
48 Reads
1.263 Impact Factor

Different Responses in Induction of Allergen Specific Immunoglobulin G4 and IgE-Blocking Factors for Three Mite Subcutaneous Immunotherapy Products.

Yonsei Med J 2016 Nov;57(6):1427-34

Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2016.57.6.1427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011275PMC
November 2016
75 Reads
1 Citation
1.263 Impact Factor

IgE Reactivity of Recombinant Pac c 3 from the Asian Needle Ant (Pachycondyla chinensis).

Int Arch Allergy Immunol 2016 5;169(2):93-100. Epub 2016 Apr 5.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000444364DOI Listing
September 2016
18 Reads
1 Citation
2.673 Impact Factor

Cross-Reactivity between Oak and Birch Pollens in Korean Tree Pollinosis.

J Korean Med Sci 2016 Aug 20;31(8):1202-7. Epub 2016 May 20.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea .

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http://dx.doi.org/10.3346/jkms.2016.31.8.1202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951548PMC
August 2016
42 Reads
3 Citations
1.253 Impact Factor

Ranitidine-induced anaphylaxis: clinical features, cross-reactivity, and skin testing.

Clin Exp Allergy 2016 Apr;46(4):631-9

Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/cea.12708DOI Listing
April 2016
25 Reads
4.769 Impact Factor

Standardization of Weed Pollen Extracts, Japanese Hop and Mugwort, in Korea.

Yonsei Med J 2016 Mar;57(2):399-406

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2016.57.2.399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740533PMC
March 2016
45 Reads
1.263 Impact Factor

Allergenic Characterization of 27-kDa Glycoprotein, a Novel Heat Stable Allergen, from the Pupa of Silkworm, Bombyx mori.

J Korean Med Sci 2016 Jan 24;31(1):18-24. Epub 2015 Dec 24.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3346/jkms.2016.31.1.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712575PMC
January 2016
91 Reads
1.253 Impact Factor

Performance of the PROTIA™ Allergy-Q® System in the Detection of Allergen-specific IgE: A Comparison With the ImmunoCAP® System.

Allergy Asthma Immunol Res 2015 Nov 26;7(6):565-72. Epub 2015 May 26.

Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2015.7.6.565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605929PMC
November 2015
33 Reads
3.084 Impact Factor

House dust mite allergen Der f 1 induces IL-8 in human basophilic cells via ROS-ERK and p38 signal pathways.

Cytokine 2015 Oct 17;75(2):356-64. Epub 2015 Jul 17.

Department of Environmental Medical Biology and Arthropods of Medical Importance Resource Bank, Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.07.011DOI Listing
October 2015
13 Reads
2.664 Impact Factor

Cross‑reactivity between group-5 and -21 mite allergens from Dermatophagoides farinae, Tyrophagus putrescentiae and Blomia tropicalis.

Mol Med Rep 2015 Oct 20;12(4):5467-74. Epub 2015 Jul 20.

Department of Environmental Medical Biology and Arthropods of Medical Importance Resource Bank, Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul 120‑752, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2015.4093DOI Listing
October 2015
16 Reads
1.484 Impact Factor

Profiles of IgE Sensitization to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20 in Korean House Dust Mite Allergy Patients.

Allergy Asthma Immunol Res 2015 Sep 30;7(5):483-8. Epub 2015 Mar 30.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2015.7.5.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509661PMC
September 2015
38 Reads
3.084 Impact Factor

Allergenic characterization of a novel allergen, homologous to chymotrypsin, from german cockroach.

Allergy Asthma Immunol Res 2015 May 18;7(3):283-9. Epub 2014 Dec 18.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2015.7.3.283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397369PMC
May 2015
6 Reads
3.084 Impact Factor

In vitro evaluation of allergen potencies of commercial house dust mite sublingual immunotherapy reagents.

Allergy Asthma Immunol Res 2015 Mar 18;7(2):124-9. Epub 2014 Dec 18.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2015.7.2.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341333PMC
March 2015
21 Reads
3.084 Impact Factor

IgE reactivity to Acarus siro extract in Korean dust mite allergic patients.

Exp Appl Acarol 2014 May 28;63(1):57-64. Epub 2013 Nov 28.

Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, 120-752, Korea.

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http://dx.doi.org/10.1007/s10493-013-9759-6DOI Listing
May 2014
33 Reads
1.622 Impact Factor

Current status of standardization of inhalant allergen extracts in Korea.

Allergy Asthma Immunol Res 2014 May 21;6(3):196-200. Epub 2014 Feb 21.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2014.6.3.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021236PMC
May 2014
15 Reads
3.084 Impact Factor

Allergenicity of recombinant profilins from Japanese hop, Humulus japonicus.

J Investig Allergol Clin Immunol 2013 ;23(5):345-50

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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January 2014
4 Reads
2.642 Impact Factor

The effects of storage conditions on the stability of house dust mite extracts.

Allergy Asthma Immunol Res 2013 Nov 19;5(6):397-401. Epub 2013 Jul 19.

Departmet of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2013.5.6.397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810547PMC
November 2013
27 Reads
3.084 Impact Factor

Identification of novel allergenic components from German cockroach fecal extract by a proteomic approach.

Int Arch Allergy Immunol 2013 14;161(4):315-24. Epub 2013 May 14.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000347034DOI Listing
October 2013
19 Reads
2.673 Impact Factor

Preparation and characterization of an extract of german cockroach from a korean source.

Allergy Asthma Immunol Res 2013 Mar 7;5(2):102-5. Epub 2012 Nov 7.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2013.5.2.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579088PMC
March 2013
16 Reads
3.084 Impact Factor

Two New and Four Unrecorded Species of Chironomidae (Diptera) in Korea

Animal Systematics Evolution and Diversity (한국동물분류학회지), Vol.28(1) : 2-11, 2012

Chironomid adults attracted to the light were collected at Dangsan-ri, Muju-eup, Muju-gun, Jeollabuk-do in 2008-2009. Two new species, Lymnophyes parakitanaides sp. nov. and Parakiefferiella mujuensis sp. nov., and four unrecorded species, Cardiolcladius capusinus, Thienemanniella vittata, Conchapelopia pallidula, and Nilotanypus dubius were found and are described with illustrations. The genera Thienemanniella and Nilotanypus have not been previously reported in Korea. The genus Thienemanniella which belongs to Orthocladiinae is characterized by the radial sector retracted and apically fused with the costa, and the genus Nilotanypus which belongs to Tanypodinae is characterized by the absence of R2+3, pubescent eyes and lack of the gonocoxal lobes.

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2012

Standardization of house dust mite extracts in Korea.

Allergy Asthma Immunol Res 2012 Nov 12;4(6):346-50. Epub 2012 Apr 12.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2012.4.6.346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479228PMC
November 2012
8 Reads
3.084 Impact Factor

House dust mite allergy in Korea: the most important inhalant allergen in current and future.

Allergy Asthma Immunol Res 2012 Nov 27;4(6):313-25. Epub 2012 Jul 27.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4168/aair.2012.4.6.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479224PMC
November 2012
58 Reads
3.084 Impact Factor

Sequence polymorphisms of Der f 1, Der p 1, Der f 2 and Der p 2 from Korean house dust mite isolates.

Exp Appl Acarol 2012 Sep 26;58(1):35-42. Epub 2012 Apr 26.

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, 50 Yonei-ro, Seodaemun-gu, Seoul, 120-752, Korea.

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http://link.springer.com/content/pdf/10.1007/s10493-012-9553
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http://link.springer.com/10.1007/s10493-012-9553-x
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http://dx.doi.org/10.1007/s10493-012-9553-xDOI Listing
September 2012
36 Reads
1.622 Impact Factor

Six New and Four Unrecorded Species of Tanytarsini (Diptera, Chironomidae, Chironominae) Found in Korea

Korean Journal of Systematic Zoology (한국동물분류학회지), Vol.27(3) : 246-261, 2011

Adult chironomid collections were carried out near Namdae stream located at Jeollabuk-do, Muju-gun, Mujueup, Dangsan-ri in 2008 and 2009. Among 21 species of the tribe Tanytarsini identified from Muju collections, six new species (Cladotanytarsus neovanderwulpi, Paratanytarsus paramikesecumdus, Rheotanytarsus parapentapodus, Rheotanytarsus sungili, Tanytarsus neotamaoctavus, and Tanytarsus synyunosecundus) and four previously unrecorded species (Cladotanytarsus vanderwulpi, Paratanytarsus inopertus, Tanytarsus tamagotoi, and Tanytarsus uresiacutus) were confirmed. They are fully described with illustrations. As a result of this report, the Korean fauna of Tanytarsini consists of 37 species, 6 genera. In total, 128 species, 52 genera, 5 subfamilies of the family Chironomidae are listed in Korea.

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2011
1 Read

Optimization of allergen standardization.

Yonsei Med J 2011 May;52(3):393-400

Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seodaemun-gu, Seoul 120-752, Korea.

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http://dx.doi.org/10.3349/ymj.2011.52.3.393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101061PMC
May 2011
1 Read
1.263 Impact Factor

Nine Polypedilum Species (Diptera, Chironomidae) New to Korea Collected Near Namdae-stream, Muju

Korean Journal of Systematic Zoology (한국동물분류학회지), Vol.26(3) : 203-216, 2010

Adult chironomids were collected at Dangsan-ri, Muju-eup, Muju-gun, Jeollabuk-do on 5 September 2008, 22 May 2009 and 28 August 2009. A total of 221 specimens belong to the genus Polypedilum Kieffer from 1,113 adult midges collected were morphologically examined, and 16 Polypedilum species were identified. One species is new (Polypedilum dangsanensis Ree et Jeong sp. nov.) and eight species are newly recorded in Korea (P. asakawasense, P. convictum, P. decematogutatus, P. japonicum, P. kamotertium, P. pullum, P. serugense, and P. unifascium). These nine species are described with illustrations. Polypedilum nubifer was the most frequently collected species, consisting of 25.8% of the Polypedilum samples

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2010

IgE binding epitopes of Bla g 6 from German cockroach

Protein and Peptide Letters, Vol.17(9) : 1170-1176, 2010

Bla g 6, a German cockroach allergen, shows homology to muscle protein troponin C. It contains four calcium-binding domains at amino acid (aa) residues 20-30, 56-67, 96-107, and 132-143, and its immunoglobulin E (IgE) reactivity is dependent upon calcium ion level. However, the IgE binding epitopes of Bla g 6 have not been investigated. This study aimed to analyze the IgE binding epitopes from the five peptide fragments of Bla g 6. The full-length of three Bla g 6 isoallergens (Bla g 6.0101, Bla g 6.0201, and Bla g 6.0301) and five peptide fragments (P1: aa 1-111, P2: aa 1-95, P3: aa 33-111, P4: aa 80-151, and P5: aa 33-151) of Bla g 6.0101 were generated by polymerase chain reaction (PCR) and expressed in Escherichia coli. Enzyme-linked immunosorbent assay (ELISA) was performed on 24 patients' sera that adjusted the final concentration 10 mM of CaCl(2) to determine the IgE activities of Bla g 6. Eight sera (33.3%), 9 sera (37.5%), and 11 sera (45.8%) showed IgE reactivity to Bla g 6.0101, Bla g 6.0201, and Bla g 6.0301, respectively. Among the sera from the positive IgE reactivity, three patients' sera were selected and the IgE reactivity was measured by ELISA with the five peptide fragments of Bla g 6. Based on IgE responses, one patient's serum exhibited the strongest IgE reactivity. We assumed that the aa between 96-151 residues, including the calcium binding domains III and IV, would be important for IgE binding. These results may provide information that will yield safe diagnostic methods and immunotherapeutics

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2010
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Fauna of Non-biting Midges (Diptera, Chironomidae) from Soyang River in Chuncheon-si, Gangwon-do, Korea

Korean Journal of Systematic Zoology (한국동물분류학회지), Vol.26(2) : 115-140, 2010

Adults of Chironomidae were collected at Soyang river sites in Chuncheon-si, Gangwon-do on 1 August and 14 September in 2008, and 1 May in 2009. A total of 794 adults were collected, consisting of 52 species, 23 genera, 4 subfamilies. Among them, 7 species were recorded in Korea for the first time, and 9 species were new to science. These 7 previously unrecorded and 9 new species are described with illustrations. Eight species still have not been identified. The subfamily Prodiamesinae and four genera: Demicryptochironomus, Parakiefferiella, Psectrocladius and Monodiamesa are the first record in Korea. Tanytarsus seohyoni n. sp. was the most dominant species, consisting of 24.6% of the total samples.

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2010

Population dynamics of five anopheles species of the Hyrcanus group in northern Gyeonggi-do, Korea.

Korean J Parasitol 2010 Dec 16;48(4):351-3. Epub 2010 Dec 16.

Department of Environmental Medical Biology, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.3347/kjp.2010.48.4.351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018589PMC
December 2010
17 Reads
0.965 Impact Factor

IgE binding epitopes of Bla g 6 from German cockroach.

Protein Pept Lett 2010 Sep;17(9):1170-6

Department of Environmental Medical Biology and Institute of Tropical Medicine, Korea National Arthropods of Medical Importance Resource Bank, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/092986610791760432DOI Listing
September 2010
7 Reads
1.070 Impact Factor

Enzymatic activities of allergen extracts from three species of dust mites and cockroaches commonly found in Korean home.

Korean J Parasitol 2010 Jun 17;48(2):151-5. Epub 2010 Jun 17.

Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.3347/kjp.2010.48.2.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892571PMC
June 2010
3 Reads
0.965 Impact Factor

IgE-binding epitope analysis of Bla g 5, the German cockroach allergen.

Protein Pept Lett 2010 May;17(5):573-7

Department of Environmental Medical Biology and Institute of Tropical Medicine, Korea National Arthropods of Medical Importance Resource Bank, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/092986610791112765DOI Listing
May 2010
3 Reads
1.070 Impact Factor

Allergenicity of recombinant troponin C from Tyrophagus putrescentiae.

Int Arch Allergy Immunol 2010 29;151(3):207-13. Epub 2009 Sep 29.

Department of Environmental Medical Biology and Institute of Tropical Medicine, Korea National Arthropods of Medical Importance Resource Bank, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000242358DOI Listing
March 2010
3 Reads
2.673 Impact Factor

Household Arthropod Allergens in Korea.

Korean Journal of Parasitology, Vol.47(suppl) : 143-153, 2009

Arthropods are important in human health, which can transmit pathogens to humans, parasitize, or produce important allergens. Allergy prevalence becomes higher in Korea recently as well as other developed countries in contrast to a decrease of infectious diseases. Allergic diseases caused by household arthropods have increased dramatically during the last few decades since human beings spend more their time for indoor activities in modernized life style. Household arthropods are one of the most common causes of allergic diseases. Biological characterization of household arthropods and researches on their allergens will provide better understanding of the pathogenesis of allergic diseases and suggest new therapeutic ways. Therefore, studies on arthropods of allergenic importance can be considered one of the major research areas in medical arthropodology and parasitology. Here, the biology of several household arthropods, including house dust mites and cockroaches, the 2 most well known arthropods living indoor together with humans worldwide, and characteristics of their allergens, especially the research activities on these allergens performed in Korea, are summarized

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2009

IgE-binding reactivity of peptide fragments of Bla g 1.02, a major German cockroach allergen.

Asian Pac J Allergy Immunol 2009 Jun-Sep;27(2-3):121-9

Department of Environmental Medical Biology and Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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November 2009
5 Reads
1.255 Impact Factor

Household arthropod allergens in Korea.

Korean J Parasitol 2009 Oct;47 Suppl:S143-53

Department of Environmental Medical Biology, Institute of Tropical Medicine and Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.3347/kjp.2009.47.S.S143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769222PMC
October 2009
3 Reads
0.965 Impact Factor

Sequence diversity of the Bla g 4 cockroach allergen, homologous to lipocalins, from Blattella germanica.

Int Arch Allergy Immunol 2009 11;148(4):339-45. Epub 2008 Nov 11.

Department of Environmental Medical Biology and Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Seoul, Korea.

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http://dx.doi.org/10.1159/000170388DOI Listing
April 2009
2 Reads
2.673 Impact Factor

IgE binding reactivity of peptide fragments of Bla g 4, a major German cockroach allergen.

Korean J Parasitol 2009 Mar 12;47(1):31-6. Epub 2009 Mar 12.

Department of Environmental Medical Biology and Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3347/kjp.2009.47.1.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655337PMC
March 2009
4 Reads
0.965 Impact Factor

Allergenicity of sigma and delta class glutathione S-transferases from the German cockroach.

Int Arch Allergy Immunol 2009 21;148(1):59-64. Epub 2008 Aug 21.

Department of Environmental Medical Biology and Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000151506DOI Listing
January 2009
1 Read
2.673 Impact Factor

Reactivity of German cockroach allergen, Bla g 2, peptide fragments to IgE antibodies in patients' sera.

Korean J Parasitol 2008 Dec 20;46(4):243-6. Epub 2008 Dec 20.

Department of Environmental Medical Biology and the Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.3347/kjp.2008.46.4.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612609PMC
December 2008
2 Reads
0.965 Impact Factor

Domestic arthropods and their allergens.

Protein Pept Lett 2007 ;14(10):934-42

Department of Parasitology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/092986607782541114DOI Listing
March 2008
1.070 Impact Factor

Sequence polymorphisms of major German cockroach allergens Bla g 1, Bla g 2, Bla g 4, and Bla g 5.

Int Arch Allergy Immunol 2008 16;145(1):1-8. Epub 2007 Aug 16.

Department of Parasitology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000107460DOI Listing
January 2008
1 Read
2.673 Impact Factor

Molecular cloning and the allergenic characterization of tropomyosin from Tyrophagus putrescentiae.

Protein Pept Lett 2007 ;14(5):431-6

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University, College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/092986607780782777DOI Listing
October 2007
2 Reads
1.070 Impact Factor

Allergenic tropomyosins and their cross-reactivities.

Protein Pept Lett 2006 ;13(8):835-45

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/092986606777841244DOI Listing
December 2006
1.070 Impact Factor

Effectiveness of education for control of house dust mites and cockroaches in Seoul, Korea.

Korean J Parasitol 2006 Mar;44(1):73-9

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University, College of Medicine, Seoul.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532652PMC
http://dx.doi.org/10.3347/kjp.2006.44.1.73DOI Listing
March 2006
4 Reads
0.965 Impact Factor

Recombinant allergens for diagnosis and immunotherapy of allergic disorders, with emphasis on cockroach allergy.

Curr Protein Pept Sci 2006 Feb;7(1):57-71

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2174/138920306775474112DOI Listing
February 2006
3 Reads
3.154 Impact Factor

Immunoglobulin E binding reactivity of a recombinant allergen homologous to alpha-Tubulin from Tyrophagus putrescentiae.

Clin Diagn Lab Immunol 2005 Dec;12(12):1451-4

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.1128/CDLI.12.12.1451-1454.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317066PMC
December 2005
26 Reads

Immunoglobulin E reactivity of recombinant allergen Tyr p 13 from Tyrophagus putrescentiae homologous to fatty acid binding protein.

Clin Diagn Lab Immunol 2005 May;12(5):581-5

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.1128/CDLI.12.5.581-585.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112090PMC
May 2005
4 Reads

Expression of tropomyosin from Blattella germanica as a recombinant non-fusion protein in Pichia pastoris and comparison of its IgE reactivity with its native counterpart.

Protein Expr Purif 2004 Oct;37(2):273-8

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University, College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.pep.2004.06.009DOI Listing
October 2004
2 Reads
1.700 Impact Factor

Analysis of amino acid sequence variations and immunoglobulin E-binding epitopes of German cockroach tropomyosin.

Clin Diagn Lab Immunol 2004 Sep;11(5):874-8

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1128/CDLI.11.5.874-878.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515276PMC
September 2004
4 Reads

Allergenic characterization of tropomyosin from the dusky brown cockroach, Periplaneta fuliginosa.

Clin Diagn Lab Immunol 2004 Jul;11(4):680-5

Department of Parasitology and Institute of Tropical Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, Korea.

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http://dx.doi.org/10.1128/CDLI.11.4.680-685.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC440615PMC
July 2004
4 Reads

Molecular cloning and characterization of tropomyosin, a major allergen of Chironomus kiiensis, a dominant species of nonbiting midges in Korea.

Clin Diagn Lab Immunol 2004 Mar;11(2):320-4

Department of Parasitology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul. South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC371210PMC
http://dx.doi.org/10.1128/cdli.11.2.320-324.2004DOI Listing
March 2004
27 Reads

서울지역 집먼지내 실내 알레르겐인 개 항원(Can f 1)과 고양이 항원(Fel d 1)의 농도 측정

Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지), Vol.13(2) : 98-105, 2003

Purpose : Allergens that cause asthma include those derived from indoor allergens such as animal dander(dog and cat). The aim of the study is to provide baseline data on characteristics of home environments in Korea, which will be used for future comparative studies of indoor environmental factors between populations with contrasting asthma prevalence. Methods : The study was performed during September through November(Autumn) 1999. A total of 206 residential homes were volunteers from different districts in Seoul. They, participate in home environment survey and skin prick tests. The dust specimens were collected by vacuum cleaner(V-582T, 520W; LG), We detected animal dander(Can f 1 and Fel d 1)by monoclonal-antibody based enzyme-linked immunosorbent assays(ELISA). Results : The average indoor temperature was 25.1±2.9˚C and the relative humidity was 54.0±9.6%. The positive rate of dog(Can f 1) was 35.4% and cat(Fel d 1) was 33.5%. It is the same between Can f 1 and Fel d 1 distributed within dust samples from the four sites of the homes. And the distribution level of Can f 1 and Fel d 1 was, for the living room 26.2%, 17%, for the bedroom 20.9%, 15%, for the children's room 20.4%, 10.2%, for the kitchen 16%. 8.7%, in descending order. Conclusion : The positive rate of Can f 1 was higher than Fel d 1 in dust samples. The living room has highest distribution of dust samples among the four sites of a home. And it has similar distribution between Can f 1 and Fel d 1.

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2003
3 Reads

실내 원인 알레르겐인 바퀴벌레의 수도권내 계절별 분포 조사

Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.22(4) : 728-735, 2002

Purpose: Home exposure to aeroallergens are an important environmental factor in allergic sensitization and in the development and exacerbation of asthma. Most studies of aeroallergens were dust mite in Korea, but cockroach distribution was little been known in Korea. The aim of this study was to evaluate species of cockroaches and seasonal distribution of cockroaches in Seoul area. Methods: The study was performed during April 2000 through January 2001, from 63 houses in Korea. The total of 63 residential homes from different distribution in Seoul were selected for the home environment survey. Bait traps (10×20×4 ㎠, Zoro Zoro, Taisho Pharmacy, Tokyo, Japan) were placed on four different place of kitchen floor and one in the side of balcony in the house and left for 5 days to capture cockroaches. Results: The cockroaches were captured in 23 houses(36.5%) out of 63 houses. And the inhabitant density of cockroaches was highest in the autumn(43.3%) followed by summer(29.2%), spring(18.3%) and winter(9.2%). In only 3 species were collected in Seoul area. The most common species were Blattella germanica showing 72.5% of the collected cockroaches, followed by Periplaneta japonica(25.2%) Periplaneta americana(2.3%). The total number of captured cockroaches was 504 and the number of nymph was 314(62.2%). Isolated house type showed higher trapping rates than the apartment. Positive skin test rates were 46.2% in the healthy control group and 43.8% in the allergy patients. Conclusion: Periplaneta americana was captured in Seoul area, which had not been found previously. The inhabitant density of cockroaches was the lowest in the winter.

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2002

Top co-authors

Chein-Soo Hong
Chein-Soo Hong

Yonsei University College of Medicine

23
Jung-Won Park
Jung-Won Park

Yonsei University College of Medicine

21
Kyung Hee Park
Kyung Hee Park

Harvard Medical School

18
Han-Il Ree
Han-Il Ree

Department of Parasitology and Institute of Tropical Medicine

9
Jae Hyun Lee
Jae Hyun Lee

Howard Hughes Medical Institute

8
Mina Son
Mina Son

Yonsei University

8