Kyong-Mi Chang

Kyong-Mi Chang

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Kyong-Mi Chang

Kyong-Mi Chang

Publications by authors named "Kyong-Mi Chang"

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Long-term use of hydrocodone vs. oxycodone in primary care.

Drug Alcohol Depend 2019 Nov 2;205:107524. Epub 2019 Nov 2.

Department of Medicine, Infectious Diseases, Department of Epidemiology, Biostatistics, Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.06.026DOI Listing
November 2019

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.

Am J Hum Genet 2019 Oct 26;105(4):763-772. Epub 2019 Sep 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; VA Palo Alto Epidemiology Research and Information Center for Genomics, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817526PMC
October 2019

Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Cell Metab 2019 Mar 31;29(3):769-783.e4. Epub 2019 Jan 31.

Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436557PMC
March 2019

Reply.

Hepatology 2018 10;68(4):1658-1660

Liver Diseases and Hepatitis Program, Alaska NativeTribal Health Consortium, Anchorage, AK.

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http://dx.doi.org/10.1002/hep.30137DOI Listing
October 2018

Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B Guidance.

Clin Liver Dis (Hoboken) 2018 Jul 22;12(1):33-34. Epub 2018 Aug 22.

Division of Clinical Decision Making, Tufts Medical Center Tufts University School of Medicine Boston MA.

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http://doi.wiley.com/10.1002/cld.728
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http://dx.doi.org/10.1002/cld.728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385899PMC
July 2018

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.

Immunity 2018 05;48(5):1029-1045.e5

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010198PMC
May 2018

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

Hepatology 2018 04;67(4):1560-1599

Division of Clinical Decision Making, Tufts Medical Center, Tufts University School of Medicine, Boston, MA.

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http://doi.wiley.com/10.1002/hep.29800
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http://dx.doi.org/10.1002/hep.29800DOI Listing
April 2018

Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns.

J Immunol Methods 2018 02 19;453:3-10. Epub 2017 Mar 19.

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2017.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605401PMC
February 2018

Strategies to Improve Hepatocellular Carcinoma Surveillance in Veterans With Hepatitis B Infection.

Fed Pract 2017 Jun;34(Suppl 4):S30-S39

is an infectious disease physician at the Nationwide Children's Hospital and assistant professor of pediatrics at the Ohio State University College of Medicine in Columbus, Ohio. is a medical student at the St. Louis University School of Medicine in Missouri. is assistant professor of clinical medicine, is associate professor of medicine, is assistant professor of medicine, and is associate professor of clinical medicine, all at Perelman School of Medicine in Philadelphia, Pennsylvania. is assistant professor of medicine and assistant professor of epidemiology in biostatistics and epidemiology at Penn Medicine in Philadelphia. Dr. Chang is associate chief of staff for research and associate dean for research, Dr. Kaplan is assistant professor of medicine, and Dr. Amorosa is an attending physician, all at the Corporal Michael J. Crescenz VAMC in Philadelphia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375474PMC
June 2017

Evolution in Our Understanding of Hepatitis B Virus Virology and Immunology.

Clin Liver Dis 2016 11 12;20(4):629-644. Epub 2016 Aug 12.

Medical Research, Philadelphia Corporal Michael J. Crescenz VA Medical Center (CMC VAMC), A424, University and Woodland Avenue, Philadelphia, PA 19104, USA; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2016.06.001DOI Listing
November 2016

Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas.

Cell Metab 2016 10;24(4):616-626

Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131163048
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http://dx.doi.org/10.1016/j.cmet.2016.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123805PMC
October 2016

Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics.

Curr Opin Pharmacol 2016 10 6;30:93-105. Epub 2016 Sep 6.

University of Pennsylvania Perelman School of Medicine, USA.

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http://dx.doi.org/10.1016/j.coph.2016.07.013DOI Listing
October 2016

Corrigendum to "Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics" [Curr. Opin. Pharmacol. 30 (2016) 93-105].

Curr Opin Pharmacol 2016 10 1;30:158-159. Epub 2016 Oct 1.

University of Pennsylvania Perelman School of Medicine, USA.

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http://dx.doi.org/10.1016/j.coph.2016.09.005DOI Listing
October 2016

Hepatitis B Virus--Specific and Global T-Cell Dysfunction in Chronic Hepatitis B.

Gastroenterology 2016 Mar 10;150(3):684-695.e5. Epub 2015 Dec 10.

Philadelphia Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.11.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766024PMC
March 2016

Present and future therapies of hepatitis B: From discovery to cure.

Hepatology 2015 Dec 27;62(6):1893-908. Epub 2015 Oct 27.

Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI.

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http://doi.wiley.com/10.1002/hep.28025
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http://dx.doi.org/10.1002/hep.28025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681668PMC
December 2015

Veterans Affairs Office of Research and Development: Research Programs and Emerging Opportunities in Digestive Diseases Research.

Gastroenterology 2015 Dec 23;149(7):1652-61. Epub 2015 Oct 23.

Corporal Michael J. Crescenz VA Medical Center and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1053/j.gastro.2015.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887273PMC
December 2015

Distinct features in natural history and outcomes of acute hepatitis C.

J Clin Gastroenterol 2015 Apr;49(4):e31-40

*Department of Medicine, University of Pennsylvania ‡Department of Medicine, Division of Gastroenterology and Hepatology, Philadelphia VA Medical Center §Pennsylvania Hospital, Philadelphia, PA †Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand ∥VA New York Harbor Healthcare System, Brooklyn, NY.

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http://dx.doi.org/10.1097/MCG.0000000000000076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112167PMC
April 2015

Prevalence and risk factors for patient-reported joint pain among patients with HIV/hepatitis C coinfection, hepatitis C monoinfection, and HIV monoinfection.

BMC Musculoskelet Disord 2015 Apr 19;16:93. Epub 2015 Apr 19.

Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/s12891-015-0552-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404567PMC
April 2015

Induction of Multiple Immune Regulatory Pathways with Differential Impact in HCV/HIV Coinfection.

Front Immunol 2014 8;5:265. Epub 2014 Jul 8.

Philadelphia VAMC , Philadelphia, PA , USA ; Department of Medicine, University of Pennsylvania School of Medicine , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086204PMC
July 2014

Evaluation of the significance of pretreatment liver biopsy and baseline mental health disorder diagnosis on hepatitis C treatment completion rates at a veterans affairs medical center.

Hepat Res Treat 2013 16;2013:653976. Epub 2013 May 16.

Department of Pharmacy, Philadelphia Veterans Affairs Medical Center, 3900 Woodland Avenue, Philadelphia, PA 19104, USA ; Department of Pharmacy, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/2013/653976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670541PMC
June 2013

Hepatitis C virus: virology and life cycle.

Clin Mol Hepatol 2013 Mar 25;19(1):17-25. Epub 2013 Mar 25.

Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3350/cmh.2013.19.1.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622851PMC
March 2013

A view to natural killer cells in hepatitis C.

Gastroenterology 2011 Oct 27;141(4):1144-8. Epub 2011 Aug 27.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085110117
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http://dx.doi.org/10.1053/j.gastro.2011.08.025DOI Listing
October 2011

Hepatitis B immunology for clinicians.

Authors:
Kyong-Mi Chang

Clin Liver Dis 2010 Aug;14(3):409-24

Philadelphia VA Medical Center & University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1016/j.cld.2010.05.012DOI Listing
August 2010

Hepatitis C virus transmission bottlenecks analyzed by deep sequencing.

J Virol 2010 Jun 7;84(12):6218-28. Epub 2010 Apr 7.

University of Pennsylvania School of Medicine, Department of Microbiology, 3610 Hamilton Walk, Philadelphia, PA 19104-6076, USA.

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http://dx.doi.org/10.1128/JVI.02271-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876626PMC
June 2010

Homeostasis of peripheral FoxP3(+) CD4 (+) regulatory T cells in patients with early and late stage breast cancer.

Cancer Immunol Immunother 2010 Apr 24;59(4):599-607. Epub 2009 Oct 24.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, 551 BRB II/III, 421 Curie Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00262-009-0780-xDOI Listing
April 2010

Determinants of in vitro expansion of different human virus-specific FoxP3+ regulatory CD8+ T cells in chronic hepatitis C virus infection.

J Gen Virol 2009 Jul 25;90(Pt 7):1692-701. Epub 2009 Mar 25.

Department of Medicine II, University Hospital Freiburg, and Faculty of Biology, Spemann Graduate School of Biology and Medicine, University of Freiburg, Germany.

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http://dx.doi.org/10.1099/vir.0.009837-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889453PMC
July 2009

Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.

J Virol 2008 Aug 11;82(16):8183-95. Epub 2008 Jun 11.

Hepatitis Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 50, Room 6531, 50 South Dr., MSC 8009, Bethesda, MD 20892-8009, USA.

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http://dx.doi.org/10.1128/JVI.00142-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519567PMC
August 2008

Human leukocyte antigen class II associations with hepatitis C virus clearance and virus-specific CD4 T cell response among Caucasians and African Americans.

Hepatology 2008 Jul;48(1):70-9

Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19014, USA.

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http://dx.doi.org/10.1002/hep.22287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749605PMC
July 2008

Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization.

Gastroenterology 2008 Jun 17;134(7):1927-37, 1937.e1-2. Epub 2008 Feb 17.

Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.02.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665722PMC
June 2008

End-stage liver disease in 2008: finally a glass half full.

Gastroenterology 2008 May;134(6):1639-40

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http://dx.doi.org/10.1053/j.gastro.2008.03.018DOI Listing
May 2008

Regulatory T cells in hepatitis C virus infection.

Authors:
Kyong-Mi Chang

Hepatol Res 2007 Oct;37 Suppl 3:S327-30

Department of Medicine, University of Pennsylvania & Philadelphia VA Medical Center, Philadelphia, USA.

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http://dx.doi.org/10.1111/j.1872-034X.2007.00220.xDOI Listing
October 2007

Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

Gastroenterology 2007 Feb 29;132(2):654-66. Epub 2006 Nov 29.

Gastroenterology Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

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http://dx.doi.org/10.1053/j.gastro.2006.11.044DOI Listing
February 2007

Hepatitis C: a new horizon.

Authors:
Kyong-Mi Chang

Gastroenterology 2006 Dec;131(6):1667-8

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http://dx.doi.org/10.1053/j.gastro.2006.10.045DOI Listing
December 2006

Racial difference in mortality among U.S. veterans with HCV/HIV coinfection.

Am J Gastroenterol 2006 Apr 22;101(4):760-7. Epub 2006 Feb 22.

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2006.00531.xDOI Listing
April 2006

Strain-specific T-cell suppression and protective immunity in patients with chronic hepatitis C virus infection.

J Virol 2005 Jun;79(11):6976-83

Department of Medicine, GI Division, University of Pennsylvania, and Philadelphia VAMC, A212 Medical Research, PVAMC, University and Woodland Avenues, Philadelphia, PA 19104, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.79.11.6976-6983.2005
Publisher Site
http://dx.doi.org/10.1128/JVI.79.11.6976-6983.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112102PMC
June 2005

T-cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C.

Hepatology 2005 Jun;41(6):1365-75

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1002/hep.20706DOI Listing
June 2005

Regulatory T cells and the liver: a new piece of the puzzle.

Authors:
Kyong-Mi Chang

Hepatology 2005 Apr;41(4):700-2

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http://dx.doi.org/10.1002/hep.20678DOI Listing
April 2005

Influence of alcohol use, race, and viral coinfections on spontaneous HCV clearance in a US veteran population.

Hepatology 2004 Oct;40(4):892-9

University of Pennsylvania School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/hep.20384DOI Listing
October 2004

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection.

Hepatology 2003 Dec;38(6):1437-48

Department of Medicine, University of Pennsylvania & Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.hep.2003.09.026DOI Listing
December 2003

A critical review of selective serotonin reuptake inhibitor-associated bleeding: balancing the risk of treating hepatitis C-infected patients.

J Clin Psychiatry 2003 Dec;64(12):1502-10

Department of Psychiatry, University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.4088/jcp.v64n1215DOI Listing
December 2003

Influence of ethnicity in the outcome of hepatitis C virus infection and cellular immune response.

Hepatology 2003 Mar;37(3):590-9

Division of Gastroenterology, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1053/jhep.2003.50103DOI Listing
March 2003

Immunopathogenesis of hepatitis C virus infection.

Authors:
Kyong-Mi Chang

Clin Liver Dis 2003 Feb;7(1):89-105

University of Pennsylvania, University Avenue, A212/Medical Research, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s1089-3261(02)00068-5DOI Listing
February 2003

Acute hepatitis C: to treat or not to treat?

Hepatology 2002 Jun;35(6):1538-40

Division of Gastroenterology and Hepatology, Hospital of the University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/hep.510350631DOI Listing
June 2002