Dr Kylie L Gorringe, PhD - Peter MacCallum Cancer Centre

Dr Kylie L Gorringe

PhD

Peter MacCallum Cancer Centre

Melbourne | Australia

Dr Kylie L Gorringe, PhD - Peter MacCallum Cancer Centre

Dr Kylie L Gorringe

PhD

Introduction

Primary Affiliation: Peter MacCallum Cancer Centre - Melbourne , Australia

Publications

30Publications

443Reads

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737PubMed Central Citations

Identifying associations between genomic alterations in tumors.

Methods Mol Biol 2013 ;1049:9-19

Cancer Genetics and Genomics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-547-7_2DOI Listing
March 2014
1 Read

Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer.

Clin Cancer Res 2013 Mar 29;19(6):1411-21. Epub 2013 Jan 29.

Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3433DOI Listing
March 2013
35 Reads
18 Citations
8.722 Impact Factor

RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary.

J Pathol 2013 Feb;229(3):469-76

Victorian Breast Cancer Research Consortium (VBCRC), Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/path.4134DOI Listing
February 2013
15 Reads
28 Citations
7.430 Impact Factor

Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations.

Clin Cancer Res 2012 Oct 13;18(19):5267-77. Epub 2012 Aug 13.

Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1103DOI Listing
October 2012
2 Reads
16 Citations
8.722 Impact Factor

MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.

PLoS One 2012 20;7(4):e35805. Epub 2012 Apr 20.

Victorian Breast Cancer Research Consortium Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035805PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334977PMC
August 2012
8 Reads
7 Citations
3.234 Impact Factor

Analysis of KLLN as a high-penetrance breast cancer predisposition gene.

Breast Cancer Res Treat 2012 Jul 13;134(2):543-7. Epub 2012 May 13.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, East Melbourne, VIC 8006, Australia.

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http://dx.doi.org/10.1007/s10549-012-2088-3DOI Listing
July 2012
23 Reads
1 Citation
3.940 Impact Factor

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma.

Breast Cancer Res Treat 2012 Jun 4;133(3):889-98. Epub 2011 Nov 4.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, East Melbourne, Victoria, VIC 8006, Australia.

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http://link.springer.com/content/pdf/10.1007/s10549-011-1835
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http://link.springer.com/10.1007/s10549-011-1835-1
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http://dx.doi.org/10.1007/s10549-011-1835-1DOI Listing
June 2012
9 Reads
17 Citations
3.940 Impact Factor

CONTRA: copy number analysis for targeted resequencing.

Bioinformatics 2012 May 2;28(10):1307-13. Epub 2012 Apr 2.

Bioinformatics Core Facility, Peter MacCallum Cancer Centre, VIC 3002, Australia.

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http://dx.doi.org/10.1093/bioinformatics/bts146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348560PMC
May 2012
19 Reads
89 Citations
4.981 Impact Factor

Copy number aberrations in benign serous ovarian tumors: a case for reclassification?

Clin Cancer Res 2011 Dec 5;17(23):7273-82. Epub 2011 Oct 5.

Centre for Cancer Genomics and Predictive Medicine, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2080DOI Listing
December 2011
3 Reads
1 Citation
8.722 Impact Factor

Analysis of the mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer.

BMC Cancer 2011 May 17;11:173. Epub 2011 May 17.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1186/1471-2407-11-173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115913PMC
May 2011
76 Reads
10 Citations
3.362 Impact Factor

Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis.

PLoS One 2010 Apr 8;5(4):e9983. Epub 2010 Apr 8.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851616PMC
April 2010
9 Reads
43 Citations
3.234 Impact Factor

Exploiting sequence similarity to validate the sensitivity of SNP arrays in detecting fine-scaled copy number variations.

Bioinformatics 2010 Apr 25;26(8):1007-14. Epub 2010 Feb 25.

Victoria Research Laboratory, National ICT Australia, Department of Computer Science and Software Engineering, University of Melbourne, Australia.

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http://dx.doi.org/10.1093/bioinformatics/btq088DOI Listing
April 2010
3 Reads
1 Citation
4.981 Impact Factor

Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis.

Genes Chromosomes Cancer 2009 Oct;48(10):931-42

VBCRC Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/gcc.20694DOI Listing
October 2009
23 Reads
21 Citations
4.041 Impact Factor

Large-scale genomic analysis of ovarian carcinomas.

Mol Oncol 2009 Apr 24;3(2):157-64. Epub 2008 Dec 24.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.molonc.2008.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527877PMC
April 2009
2 Reads
14 Citations
5.331 Impact Factor

Genetic analysis of cancer-implicated MicroRNA in ovarian cancer.

Clin Cancer Res 2008 Nov;14(22):7246-50

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1348DOI Listing
November 2008
8 Reads
11 Citations
8.722 Impact Factor

High-resolution copy number arrays in cancer and the problem of normal genome copy number variation.

Genes Chromosomes Cancer 2008 Nov;47(11):933-8

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/gcc.20595DOI Listing
November 2008
1 Read
3 Citations
4.041 Impact Factor

Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer.

Neoplasia 2008 Nov;10(11):1253-8

Victorian Breast Cancer Research Consortium, Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570601PMC
http://dx.doi.org/10.1593/neo.08718DOI Listing
November 2008
18 Reads
29 Citations

Breast cancer risk and the BRCA1 interacting protein CTIP.

Breast Cancer Res Treat 2008 Nov 20;112(2):351-2. Epub 2007 Dec 20.

VBCRC Cancer Research Laboratory, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/s10549-007-9862-7DOI Listing
November 2008
9 Reads
1 Citation
3.940 Impact Factor

BARD1 variants are not associated with breast cancer risk in Australian familial breast cancer.

Breast Cancer Res Treat 2008 Oct 31;111(3):505-9. Epub 2007 Oct 31.

Peter MacCallum Cancer Centre, East Melbourne, VIC, 8006, Australia.

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http://dx.doi.org/10.1007/s10549-007-9799-xDOI Listing
October 2008
2 Reads
3 Citations
3.940 Impact Factor

A rational approach to cancer therapy.

Genome Biol 2008 7;9(5):306. Epub 2008 May 7.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1186/gb-2008-9-5-306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441459PMC
July 2008
2 Reads

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas.

Nat Genet 2008 May 13;40(5):650-5. Epub 2008 Apr 13.

VBCRC Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1038/ng.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745022PMC
May 2008
33 Reads
103 Citations
29.352 Impact Factor

High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications.

Clin Cancer Res 2007 Aug;13(16):4731-9

Victorian Breast Cancer Research Consortium Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0502DOI Listing
August 2007
13 Reads
48 Citations
8.722 Impact Factor

Gender differences in publication output: towards an unbiased metric of research performance.

PLoS One 2006 Dec 27;1:e127. Epub 2006 Dec 27.

Department of Zoology, University of Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000127PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762413PMC
December 2006
11 Reads
24 Citations
3.234 Impact Factor

A molecular model for sporadic human aneuploidy.

Trends Genet 2006 Apr 23;22(4):218-24. Epub 2006 Feb 23.

Comparative Genomics Centre, James Cook University, Townsville, QLD 4811, Australia.

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http://dx.doi.org/10.1016/j.tig.2006.02.007DOI Listing
April 2006
6 Reads
9 Citations
9.920 Impact Factor

Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.

Carcinogenesis 2005 May 27;26(5):923-30. Epub 2005 Jan 27.

Cancer Genomics Program, Department of Oncology, Hutchison/MRC Research Centre, University of Cambridge, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1093/carcin/bgi032DOI Listing
May 2005
6 Reads
14 Citations
5.334 Impact Factor

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization.

Genes Chromosomes Cancer 2005 Mar;42(3):247-59

Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Melbourne, Australia.

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http://dx.doi.org/10.1002/gcc.20136DOI Listing
March 2005
8 Reads
33 Citations
4.041 Impact Factor

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Ronny Drapkin
Ronny Drapkin

Perelman School of Medicine, University of Pennsylvania