Publications by authors named "Kyle S Smith"

45Publications

DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.

Dev Cell 2020 Aug 17;54(4):455-470.e5. Epub 2020 Jun 17.

CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483908PMC
August 2020

Sign-tracking behavior is sensitive to outcome devaluation in a devaluation context-dependent manner: implications for analyzing habitual behavior.

Learn Mem 2020 Apr 16;27(4):136-149. Epub 2020 Mar 16.

Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1101/lm.051144.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079568PMC
April 2020

Complementary Control over Habits and Behavioral Vigor by Phasic Activity in the Dorsolateral Striatum.

J Neurosci 2020 03 22;40(10):2139-2153. Epub 2020 Jan 22.

Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755

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http://dx.doi.org/10.1523/JNEUROSCI.1313-19.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055129PMC
March 2020

Circuit directionality for motivation: Lateral accumbens-pallidum, but not pallidum-accumbens, connections regulate motivational attraction to reward cues.

Neurobiol Learn Mem 2019 07 13;162:23-35. Epub 2019 May 13.

Dartmouth College, Department of Psychological and Brain Sciences, United States.

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http://dx.doi.org/10.1016/j.nlm.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405784PMC
July 2019

Evidence for a shared representation of sequential cues that engage sign-tracking.

Behav Processes 2018 Dec 19;157:489-494. Epub 2018 Jun 19.

Department of Psychological and Brain Sciences, Dartmouth College, United States.

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http://dx.doi.org/10.1016/j.beproc.2018.06.010DOI Listing
December 2018

Context-driven Salt Seeking Test (Rats).

Bio Protoc 2018 Apr;8(7)

Dartmouth College, Department of Psychological and Brain Sciences, Hanover, NH, United States.

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http://dx.doi.org/10.21769/BioProtoc.2456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951410PMC
April 2018

Paradoxical accentuation of motivation following accumbens-pallidum disconnection.

Neurobiol Learn Mem 2018 03 3;149:39-45. Epub 2018 Feb 3.

Dartmouth College, Department of Psychological and Brain Sciences, 6207 Moore Hall, Hanover, NH 03755, United States.

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http://dx.doi.org/10.1016/j.nlm.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864546PMC
March 2018

Evidence of structure and persistence in motivational attraction to serial Pavlovian cues.

Learn Mem 2018 02 16;25(2):78-89. Epub 2018 Jan 16.

Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1101/lm.046599.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772391PMC
February 2018

Nuclear topology modulates the mutational landscapes of cancer genomes.

Nat Struct Mol Biol 2017 Nov 2;24(11):1000-1006. Epub 2017 Oct 2.

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.1038/nsmb.3474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744871PMC
November 2017

Optogenetic Inhibition of Ventral Pallidum Neurons Impairs Context-Driven Salt Seeking.

J Neurosci 2017 06 11;37(23):5670-5680. Epub 2017 May 11.

Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, and.

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http://dx.doi.org/10.1523/JNEUROSCI.2968-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469304PMC
June 2017

The Head-Direction Signal Plays a Functional Role as a Neural Compass during Navigation.

Curr Biol 2017 May 13;27(9):1259-1267. Epub 2017 Apr 13.

Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425164PMC
May 2017

Significance of duon mutations in cancer genomes.

Sci Rep 2016 06 8;6:27437. Epub 2016 Jun 8.

Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1038/srep27437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897603PMC
June 2016

Habit formation.

Dialogues Clin Neurosci 2016 Mar;18(1):33-43

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826769PMC
March 2016

An omission procedure reorganizes the microstructure of sign-tracking while preserving incentive salience.

Learn Mem 2016 Apr 15;23(4):151-5. Epub 2016 Mar 15.

Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1101/lm.041574.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793197PMC
April 2016

DREADDS: Use and application in behavioral neuroscience.

Behav Neurosci 2016 Apr 25;130(2):137-55. Epub 2016 Feb 25.

Department of Neurobiology and Behavior, University of California Irvine.

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http://dx.doi.org/10.1037/bne0000135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792665PMC
April 2016

Habit formation coincides with shifts in reinforcement representations in the sensorimotor striatum.

J Neurophysiol 2016 Mar 6;115(3):1487-98. Epub 2016 Jan 6.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts.

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http://jn.physiology.org/content/jn/early/2016/01/04/jn.0092
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https://jn.physiology.org/content/jn/115/3/1487.full.pdf
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http://jn.physiology.org/lookup/doi/10.1152/jn.00925.2015
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http://dx.doi.org/10.1152/jn.00925.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808096PMC
March 2016

SomVarIUS: somatic variant identification from unpaired tissue samples.

Bioinformatics 2016 03 20;32(6):808-13. Epub 2015 Nov 20.

Department of Medicine, Department of Pharmacology, Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv685DOI Listing
March 2016

Chemogenetic manipulation of ventral pallidal neurons impairs acquisition of sign-tracking in rats.

Eur J Neurosci 2015 Dec;42(12):3105-16

Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH, 03755, USA.

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http://doi.wiley.com/10.1111/ejn.13103
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http://dx.doi.org/10.1111/ejn.13103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715659PMC
December 2015

Signatures of accelerated somatic evolution in gene promoters in multiple cancer types.

Nucleic Acids Res 2015 Jun 1;43(11):5307-17. Epub 2015 May 1.

Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA Computational Biosciences Program, University of Colorado-Denver, Aurora, CO, USA University of Colorado Cancer Center, Aurora, CO, USA Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA

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http://dx.doi.org/10.1093/nar/gkv419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477653PMC
June 2015

Good habits, bad habits.

Sci Am 2014 Jun;310(6):38-43

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http://dx.doi.org/10.1038/scientificamerican0614-38DOI Listing
June 2014

Investigating habits: strategies, technologies and models.

Front Behav Neurosci 2014 12;8:39. Epub 2014 Feb 12.

Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA, USA.

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http://dx.doi.org/10.3389/fnbeh.2014.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921576PMC
March 2014

A dual operator view of habitual behavior reflecting cortical and striatal dynamics.

Neuron 2013 Jul 27;79(2):361-74. Epub 2013 Jun 27.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.neuron.2013.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951965PMC
July 2013

Using optogenetics to study habits.

Brain Res 2013 May 10;1511:102-14. Epub 2013 Jan 10.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, United States.

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http://dx.doi.org/10.1016/j.brainres.2013.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654045PMC
May 2013

Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex.

Proc Natl Acad Sci U S A 2012 Nov 29;109(46):18932-7. Epub 2012 Oct 29.

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.1216264109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503190PMC
November 2012

Neuronal correlates of normal and drug-potentiated Pavlovian-instrumental transfer (Commentary on Saddoris et al.).

Authors:
Kyle S Smith

Eur J Neurosci 2011 Jun;33(12):2272-3

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2011.07716.xDOI Listing
June 2011

Disentangling pleasure from incentive salience and learning signals in brain reward circuitry.

Proc Natl Acad Sci U S A 2011 Jul 13;108(27):E255-64. Epub 2011 Jun 13.

Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.1101920108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131314PMC
July 2011

Hedonic and motivational roles of opioids in food reward: implications for overeating disorders.

Pharmacol Biochem Behav 2010 Nov 24;97(1):34-46. Epub 2010 May 24.

Department of Behavioral Sciences, University of Michigan-Dearborn, Dearborn, MI 48128, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009130571000163
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http://dx.doi.org/10.1016/j.pbb.2010.05.016DOI Listing
November 2010

Corticostriatal Interactions during Learning, Memory Processing, and Decision Making.

J Neurosci 2009 Oct;29(41):12831-8

University of Amsterdam, Swammerdam Institute for Life Sciences Center for Neuroscience, 1098 XH Amsterdam, The Netherlands.

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http://dx.doi.org/10.1523/JNEUROSCI.3177-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849625PMC
October 2009

Dynamic computation of incentive salience: "wanting" what was never "liked".

J Neurosci 2009 Sep;29(39):12220-8

Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109-1043, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2499-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792765PMC
September 2009

A neural computational model of incentive salience.

PLoS Comput Biol 2009 Jul 17;5(7):e1000437. Epub 2009 Jul 17.

Department of Psychology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1000437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703828PMC
July 2009

Ventral pallidum roles in reward and motivation.

Behav Brain Res 2009 Jan 8;196(2):155-67. Epub 2008 Oct 8.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.bbr.2008.09.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606924PMC
January 2009

Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward.

Neuropsychopharmacology 2007 Nov 4;32(11):2267-78. Epub 2007 Apr 4.

Department of Psychology, The University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1038/sj.npp.1301376DOI Listing
November 2007

Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum.

J Neurosci 2007 Feb;27(7):1594-605

Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4205-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673729PMC
February 2007

Hedonic hot spots in the brain.

Neuroscientist 2006 Dec;12(6):500-11

Department of Psychology, University of Michigan, Ann Arbor, MI 48109-1109, USA.

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http://dx.doi.org/10.1177/1073858406293154DOI Listing
December 2006

Ventral pallidum firing codes hedonic reward: when a bad taste turns good.

J Neurophysiol 2006 Nov 2;96(5):2399-409. Epub 2006 Aug 2.

Department of Psychology, University of Michigan Medical School, 1150 West Medical Center Drive, Medical Science Bldg I, Room 3317, Ann Arbor, MI 48109-0607, USA.

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http://dx.doi.org/10.1152/jn.00576.2006DOI Listing
November 2006

The ventral pallidum and hedonic reward: neurochemical maps of sucrose "liking" and food intake.

J Neurosci 2005 Sep;25(38):8637-49

Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1902-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725525PMC
September 2005