Kyle E Brown

Kyle E Brown

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Kyle E Brown

Kyle E Brown

Publications by authors named "Kyle E Brown"

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ACG Clinical Guideline: Hereditary Hemochromatosis.

Am J Gastroenterol 2019 Aug;114(8):1202-1218

Department of Medicine and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California.

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http://dx.doi.org/10.14309/ajg.0000000000000315DOI Listing
August 2019

Iron-Induced Liver Injury: A Critical Reappraisal.

Int J Mol Sci 2019 Apr 30;20(9). Epub 2019 Apr 30.

Iowa City Veterans Administration Medical Center, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.3390/ijms20092132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539962PMC
April 2019

Renal iron accumulation and oxidative injury with aging: effects of treatment with an iron chelator.

J Gerontol A Biol Sci Med Sci 2019 Feb 22. Epub 2019 Feb 22.

Department of Health and Human Physiology, The University of Iowa.

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http://dx.doi.org/10.1093/gerona/glz055DOI Listing
February 2019

Clinical burden of liver disease from hemochromatosis at an academic medical center.

Hepatol Commun 2017 07 18;1(5):453-459. Epub 2017 May 18.

Iowa City Veterans Administration Medical Center Iowa City IA.

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http://dx.doi.org/10.1002/hep4.1048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721419PMC
July 2017

Corrigendum: Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis.

Cell Biochem Funct 2017 04;35(3):192-193

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1002/cbf.3261DOI Listing
April 2017

Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis.

Cell Biochem Funct 2016 Dec;34(8):628-639

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1002/cbf.3238DOI Listing
December 2016

Mirizzi Syndrome in a Cirrhotic Patient After TIPS Resolved by Technetium Mebrofenin Hepatobiliary Scan.

ACG Case Rep J 2016 Aug 17;3(4):e100. Epub 2016 Aug 17.

Department of Gastroenterology and Hepatology, University of Iowa Hospitals and Clinics, Iowa City, IA.

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http://dx.doi.org/10.14309/crj.2016.73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062646PMC
August 2016

Tumour promotion versus tumour suppression in chronic hepatic iron overload.

Cell Biochem Funct 2015 Jun 9;33(4):241-8. Epub 2015 Jun 9.

Iowa City Veterans Administration Medical Center, Iowa City, IA, USA.

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http://dx.doi.org/10.1002/cbf.3110DOI Listing
June 2015

Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes.

Redox Biol 2013 5;1:172-7. Epub 2013 Feb 5.

Free Radical and Radiation Biology Program, Department of Radiation Oncology, Carver College of Medicine and the Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.redox.2013.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757676PMC
May 2015

Iron overload secondary to cirrhosis: a mimic of hereditary haemochromatosis?

Histopathology 2014 Oct 16;65(4):561-9. Epub 2014 May 16.

Division of Gastroenterology-Hepatology, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.

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http://doi.wiley.com/10.1111/his.12417
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http://dx.doi.org/10.1111/his.12417DOI Listing
October 2014

Heat stress stimulates hepcidin mRNA expression and C/EBPα protein expression in aged rodent liver.

Arch Gerontol Geriatr 2014 Jan-Feb;58(1):145-52. Epub 2013 Aug 8.

Division of Science and Engineering, Penn State Abington College, Abington, PA, United States; Department of Health and Human Physiology, The University of Iowa, Iowa City, IA 52242, United States. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2013.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808518PMC
June 2014

Altered expression of iron regulatory proteins with aging is associated with transient hepatic iron accumulation after environmental heat stress.

Blood Cells Mol Dis 2014 Jan 27;52(1):19-26. Epub 2013 Jul 27.

Division of Science and Engineering, Penn State Abington College, Abington, PA 19001, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10799796130015
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http://dx.doi.org/10.1016/j.bcmd.2013.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851592PMC
January 2014

Hereditary hemochromatosis: missed diagnosis or misdiagnosis?

Am J Med 2013 Nov 18;126(11):1010-5. Epub 2013 Sep 18.

Department of Internal Medicine, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa.

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http://dx.doi.org/10.1016/j.amjmed.2013.07.013DOI Listing
November 2013

Interventions and outcomes of treatment of postbanding ulcer hemorrhage after endoscopic band ligation: a single-center case series.

Gastrointest Endosc 2013 Jan 11;77(1):136-140.e1. Epub 2012 Oct 11.

Department of Internal Medicine, Washington University, St. Louis, MO 63143, USA.

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http://dx.doi.org/10.1016/j.gie.2012.08.031DOI Listing
January 2013

Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells.

J Med Virol 2010 Feb;82(2):239-48

Department of Internal Medicine and Research Service, Veterans Administration Medical Center, Iowa City, Iowa, USA.

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http://doi.wiley.com/10.1002/jmv.21644
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http://dx.doi.org/10.1002/jmv.21644DOI Listing
February 2010

Increased plasma nitric oxide, L-arginine, and arginase-1 in cirrhotic patients with progressive renal dysfunction.

J Gastroenterol Hepatol 2009 Jun 15;24(6):1030-7. Epub 2009 Feb 15.

Transplantation Institute, Loma Linda University Medical Center and Loma Linda University School of Medicine, Loma Linda, California 92354, USA.

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http://dx.doi.org/10.1111/j.1440-1746.2008.05757.xDOI Listing
June 2009

Differential regulation of hepatic heme oxygenase-1 protein with aging and heat stress.

J Gerontol A Biol Sci Med Sci 2009 Apr 4;64(4):419-25. Epub 2009 Feb 4.

Department of Integrative Physiology, 532 FH, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1093/gerona/gln056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657177PMC
April 2009

Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis?

Lab Invest 2008 Dec 6;88(12):1349-57. Epub 2008 Oct 6.

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://www.nature.com/articles/labinvest200895
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http://dx.doi.org/10.1038/labinvest.2008.95DOI Listing
December 2008

Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury.

Hepatology 2008 Nov;48(5):1430-9

Department of Internal Medicine and Research Service, Veterans Administration Medical Center, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1002/hep.22491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587102PMC
November 2008

Hepatitis C core protein inhibits induction of heme oxygenase-1 and sensitizes hepatocytes to cytotoxicity.

Cell Biol Toxicol 2008 Apr 25;24(2):175-88. Epub 2007 Aug 25.

Department of Internal Medicine, Roy G and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1007/s10565-007-9027-9DOI Listing
April 2008

Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury.

Am J Physiol Regul Integr Comp Physiol 2008 Apr 13;294(4):R1165-74. Epub 2008 Feb 13.

Department of Integrative Physiology, The University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1152/ajpregu.00719.2007DOI Listing
April 2008

A systematic review of provider knowledge of hepatitis C: is it enough for a complex disease?

Dig Dis Sci 2007 Oct 4;52(10):2550-6. Epub 2007 Apr 4.

VA Pittsburgh Healthcare System, Center for Health Equity Research and Promotion, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA.

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http://dx.doi.org/10.1007/s10620-007-9753-0DOI Listing
October 2007

Differential expression of stress-inducible proteins in chronic hepatic iron overload.

Toxicol Appl Pharmacol 2007 Sep 25;223(2):180-6. Epub 2007 May 25.

Iowa City Veterans Administration Medical Center, Division of Gastroenterology-Hepatology, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City 52242, USA.

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http://dx.doi.org/10.1016/j.taap.2007.05.011DOI Listing
September 2007

Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver.

Transl Res 2006 Aug;148(2):55-62

Iowa City Veterans Administration Medical Center, Iowa City, IA, USA.

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http://dx.doi.org/10.1016/j.trsl.2006.03.002DOI Listing
August 2006

Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver.

Lab Invest 2005 Jun;85(6):789-97

Iowa City Veterans Administration Medical Center, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1038/labinvest.3700271DOI Listing
June 2005

Hemosiderosis is associated with accelerated decompensation and decreased survival in patients with cirrhosis.

Liver Int 2005 Feb;25(1):41-8

Division of Gastroenterology and Hepatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/j.1478-3231.2005.01022.xDOI Listing
February 2005

Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein.

J Infect Dis 2004 Sep 17;190(6):1109-18. Epub 2004 Aug 17.

Department of Internal Medicine and Research Service, Veterans Administration Medical Center, Roy G. and Lucille A. Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1086/423488DOI Listing
September 2004

Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats.

Liver Int 2003 Aug;23(4):232-42

Gastroenterology Section, John Cochran VAMC, St. Louis, MO, USA.

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August 2003

Hepatic iron overload in blacks and whites: a comparative autopsy study.

Am J Gastroenterol 2003 Jul;98(7):1594-8

John Cochran Veterans Affairs Medical Center, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2003.07538.xDOI Listing
July 2003

Aldehydic products of lipid peroxidation do not directly activate rat hepatic stellate cells.

J Gastroenterol Hepatol 2002 Jul;17(7):785-90

Department of Medicine, University of Western Australia, Western Australian Institute of Medical Research, Perth, Australia.

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http://dx.doi.org/10.1046/j.1440-1746.2002.02798.xDOI Listing
July 2002

Limited success of HCV antiviral therapy in United States veterans.

Am J Gastroenterol 2002 Jan;97(1):149-55

St. Louis VA Medical Center, Missouri, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2002.05439.xDOI Listing
January 2002