Kyle A Furge

Kyle A Furge

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Kyle A Furge

Kyle A Furge

Publications by authors named "Kyle A Furge"

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Rolapitant Is a Reversible Inhibitor of CYP2D6.

Drug Metab Dispos 2019 06 5;47(6):567-573. Epub 2019 Apr 5.

Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan

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http://dx.doi.org/10.1124/dmd.118.085928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505376PMC
June 2019

Evaluation of sex-specific gene expression in archived dried blood spots (DBS).

Int J Mol Sci 2012 2;13(8):9599-608. Epub 2012 Aug 2.

Program of Biospecimen Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA; E-Mails: (J.H.R.); (S.J.).

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http://www.mdpi.com/1422-0067/13/8/9599
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http://dx.doi.org/10.3390/ijms13089599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431816PMC
August 2015

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.

Mol Cancer Ther 2013 Sep 26;12(9):1701-14. Epub 2013 Jun 26.

Corresponding Author: Nicholas S. Duesbery, Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, 333 Bostwick Ave., NE, Grand Rapids, MI 49503.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769440PMC
September 2013

CUL3 and NRF2 mutations confer an NRF2 activation phenotype in a sporadic form of papillary renal cell carcinoma.

Cancer Res 2013 Apr 30;73(7):2044-51. Epub 2013 Jan 30.

Interdisciplinary Renal Oncology Laboratory, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3227DOI Listing
April 2013

Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.

PLoS One 2012 12;7(6):e38955. Epub 2012 Jun 12.

Laboratory of Molecular Oncology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038955PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373526PMC
November 2012

Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors.

Chin J Cancer 2012 Sep 2;31(9):413-20. Epub 2012 Jul 2.

Laboratory of Interdisciplinary Urological Oncology, Van Andel Research Institute, 333 Bostwick Ave NE, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.5732/cjc.012.10102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777506PMC
September 2012

Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma.

Cancer Res 2012 Sep 17;72(17):4361-71. Epub 2012 Jul 17.

Laboratories of Cancer Genetics, Cytogenetics, and Computational Biology, Van Andel Research Institute; Department of Urology, Spectrum Health Hospital, Grand Rapids, MI 49503, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-2330DOI Listing
September 2012

Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysis.

BMC Res Notes 2012 Jul 23;5:370. Epub 2012 Jul 23.

Center for Cancer Genomics and Computational Biology, Van Andel Research Institute, Grand Rapids, MI, USA.

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http://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0
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http://dx.doi.org/10.1186/1756-0500-5-370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599284PMC
July 2012

MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.

PLoS One 2011 Feb 18;6(2):e17165. Epub 2011 Feb 18.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041822PMC
February 2011

Comparative gene expression profiling analysis of urothelial carcinoma of the renal pelvis and bladder.

BMC Med Genomics 2010 Dec 15;3:58. Epub 2010 Dec 15.

Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1186/1755-8794-3-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022544PMC
December 2010

Renal medullary carcinoma: molecular, pathological and clinical evidence for treatment with topoisomerase-inhibiting therapy.

BJU Int 2010 Jul 11;106(1):62-5. Epub 2009 Dec 11.

The James Buchanan Brady Urologic Institute, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1111/j.1464-410X.2009.09139.xDOI Listing
July 2010

Kinase targets in renal-cell carcinomas: reassessing the old and discovering the new.

Lancet Oncol 2010 Jun 8;11(6):571-8. Epub 2010 Apr 8.

Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, MI, USA.

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http://dx.doi.org/10.1016/S1470-2045(09)70380-8DOI Listing
June 2010

Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma.

Cancer Res 2010 Feb 26;70(3):1063-71. Epub 2010 Jan 26.

Laboratory of Cancer Genetics, Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-09-3965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719378PMC
February 2010

MicroRNA profiling of human kidney cancer subtypes.

Int J Oncol 2009 Jul;35(1):109-14

Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.3892/ijo_00000318DOI Listing
July 2009

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.

PLoS One 2009 Jun 5;4(6):e5813. Epub 2009 Jun 5.

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005813PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686096PMC
June 2009

Regulation of endocytosis via the oxygen-sensing pathway.

Nat Med 2009 Mar 1;15(3):319-24. Epub 2009 Mar 1.

Department of Laboratory Medicine and Pathobiology, St. Michael's Hospital, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1038/nm.1922DOI Listing
March 2009

A comparison study reveals important features of agreement and disagreement between summarized DNA and RNA data obtained from renal cell carcinoma.

Mutat Res 2008 Nov 23;657(1):77-83. Epub 2008 Aug 23.

Laboratory of Cancer Genetics, Van Andel Research Institute, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1016/j.mrgentox.2008.08.009DOI Listing
November 2008

The E2F3-Oncomir-1 axis is activated in Wilms' tumor.

Cancer Res 2008 Jun;68(11):4034-8

Laboratory of Molecular Epidemiology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442735PMC
June 2008

Experimental approaches to microarray analysis of tumor samples.

Biochem Mol Biol Educ 2008 Mar;36(2):149-52

Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan 49006-3295.

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http://doi.wiley.com/10.1002/bmb.20161
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http://dx.doi.org/10.1002/bmb.20161DOI Listing
March 2008

Gene expression profiling in kidney cancer: combining differential expression and chromosomal and pathway analyses.

Clin Genitourin Cancer 2006 Dec;5(3):227-31

Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, MI, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S155876731170185
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http://dx.doi.org/10.3816/CGC.2006.n.041DOI Listing
December 2006

Diminished transcription of chromosome arm 4q is inversely related to local spreading of hepatocellular carcinoma.

Genes Chromosomes Cancer 2004 Dec;41(4):390-4

Bioinformatics Special Program, Van Andel Research Institute, 333 Bostwick, N.E., Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1002/gcc.20090DOI Listing
December 2004

Gene expression profiling of renal cell carcinoma.

Clin Cancer Res 2004 Sep;10(18 Pt 2):6315S-21S

Laboratory of Cancer Genetics, and Bioinformatics Special Program, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-050002DOI Listing
September 2004

Identification of frequent cytogenetic aberrations in hepatocellular carcinoma using gene-expression microarray data.

Genome Biol 2002 25;3(12):RESEARCH0075. Epub 2002 Nov 25.

Bioinformatics Program, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151177PMC
http://dx.doi.org/10.1186/gb-2002-3-12-research0075DOI Listing
June 2003

CIT: identification of differentially expressed clusters of genes from microarray data.

Bioinformatics 2002 Jan;18(1):205-6

Laboratory of DNA and Protein Microarray Technology, Van Andel Research Institute, Grand Rapids, MI 49053, USA.

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http://dx.doi.org/10.1093/bioinformatics/18.1.205DOI Listing
January 2002