Kwanghun Chung

Kwanghun Chung

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Kwanghun Chung

Kwanghun Chung

Publications by authors named "Kwanghun Chung"

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Publisher Correction: Tissue clearing and its applications in neuroscience.

Nat Rev Neurosci 2020 Mar 9. Epub 2020 Mar 9.

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.

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http://dx.doi.org/10.1038/s41583-020-0291-5DOI Listing
March 2020

Tissue clearing and its applications in neuroscience.

Nat Rev Neurosci 2020 Feb;21(2):61-79

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.

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http://dx.doi.org/10.1038/s41583-019-0250-1DOI Listing
February 2020

3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.

Commun Biol 2019 4;2:360. Epub 2019 Oct 4.

1The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA USA.

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http://dx.doi.org/10.1038/s42003-019-0599-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778135PMC
October 2019

Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.

Cell 2019 04 14;177(2):256-271.e22. Epub 2019 Mar 14.

Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774262PMC
April 2019

Accelerating the production of insulating brain cells.

Authors:
Kwanghun Chung

Sci Transl Med 2017 07;9(398)

Department of Chemical Engineering, Institute for Medical Engineering and Science (IMES), Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Email:

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http://dx.doi.org/10.1126/scitranslmed.aan8203DOI Listing
July 2017

Modeling human brain development.

Authors:
Kwanghun Chung

Sci Transl Med 2017 06;9(393)

Department of Chemical Engineering, Institute for Medical Engineering and Science (IMES), Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Email:

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http://dx.doi.org/10.1126/scitranslmed.aan4295DOI Listing
June 2017

Self-organized developmental patterning and differentiation in cerebral organoids.

EMBO J 2017 05 10;36(10):1316-1329. Epub 2017 Mar 10.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria

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http://dx.doi.org/10.15252/embj.201694700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430225PMC
May 2017

Label-free volumetric optical imaging of intact murine brains.

Sci Rep 2017 04 12;7:46306. Epub 2017 Apr 12.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/srep46306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388920PMC
April 2017

Toward off-the-shelf adoptive T cell therapies.

Authors:
Kwanghun Chung

Sci Transl Med 2017 04;9(386)

Department of Chemical Engineering, Institute for Medical Engineering and Science (IMES), Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Email:

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http://dx.doi.org/10.1126/scitranslmed.aan2779DOI Listing
April 2017

Kill or be killed: The epic battle between Zika virus and cells revealed.

Authors:
Kwanghun Chung

Sci Transl Med 2017 03;9(380)

Department of Chemical Engineering, Institute for Medical Engineering and Science (IMES), Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Email:

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http://dx.doi.org/10.1126/scitranslmed.aam9859DOI Listing
March 2017

Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues.

Nat Biotechnol 2016 09 25;34(9):973-81. Epub 2016 Jul 25.

Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070610PMC
http://dx.doi.org/10.1038/nbt.3641DOI Listing
September 2016

Whole-brain imaging reaches new heights (and lengths).

Elife 2016 01 20;5:e13367. Epub 2016 Jan 20.

The Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, United States.

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http://dx.doi.org/10.7554/eLife.13367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744199PMC
January 2016

Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems.

Cell 2015 Dec;163(6):1500-14

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674150150
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http://dx.doi.org/10.1016/j.cell.2015.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5275966PMC
December 2015

Stochastic electrotransport selectively enhances the transport of highly electromobile molecules.

Proc Natl Acad Sci U S A 2015 Nov 2;112(46):E6274-83. Epub 2015 Nov 2.

Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139; Broad Institute of Harvard and Massachusetts Institute of technology, Cambridge, MA 02142

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http://dx.doi.org/10.1073/pnas.1510133112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655572PMC
November 2015

Light microscopy mapping of connections in the intact brain.

Trends Cogn Sci 2013 Dec 6;17(12):596-9. Epub 2013 Nov 6.

Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1016/j.tics.2013.10.005DOI Listing
December 2013

CLARITY for mapping the nervous system.

Nat Methods 2013 Jun;10(6):508-13

Department of Bioengineering, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.2481DOI Listing
June 2013

Microfluidic chamber arrays for whole-organism behavior-based chemical screening.

Lab Chip 2011 Nov 20;11(21):3689-3697. Epub 2011 Sep 20.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr, NW, Atlanta, GA, 30332-0100, USA.

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http://dx.doi.org/10.1039/c1lc20400aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924777PMC
November 2011

A computational statistics approach for estimating the spatial range of morphogen gradients.

Development 2011 Nov 17;138(22):4867-74. Epub 2011 Oct 17.

Department of Chemical and Biological Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1242/dev.071571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201657PMC
November 2011

Imaging single-cell signaling dynamics with a deterministic high-density single-cell trap array.

Anal Chem 2011 Sep 23;83(18):7044-52. Epub 2011 Aug 23.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States.

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http://dx.doi.org/10.1021/ac2011153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190639PMC
September 2011

Gene regulation by MAPK substrate competition.

Dev Cell 2011 Jun;20(6):880-7

Department of Chemical and Biological Engineering, Lewis-Sigler Institute for Integrative Genomics, Princeton University, NJ 08544, USA.

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http://dx.doi.org/10.1016/j.devcel.2011.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580161PMC
June 2011

A microfluidic array for large-scale ordering and orientation of embryos.

Nat Methods 2011 Feb 26;8(2):171-176. Epub 2010 Dec 26.

School of Chemical & Biomolecular Engineering and Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0100, USA.

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http://dx.doi.org/10.1038/nmeth.1548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100329PMC
February 2011

Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms.

Lab Chip 2010 Jun 9;10(12):1509-17. Epub 2010 Apr 9.

Interdisciplinary Program in Bioengineering, Georgia Institute of Technology, 311 Ferst Dr NW, Atlanta, GA, USA.

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http://dx.doi.org/10.1039/b927258eDOI Listing
June 2010

Multiplex pressure measurement in microsystems using volume displacement of particle suspensions.

Lab Chip 2009 Dec 30;9(23):3345-53. Epub 2009 Sep 30.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.1039/b911480gDOI Listing
December 2009

Automated high-throughput cell microsurgery on-chip.

Lab Chip 2009 Oct 19;9(19):2764-6. Epub 2009 Aug 19.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.1039/b910703gDOI Listing
October 2009

Three-dimensional in situ temperature measurement in microsystems using Brownian motion of nanoparticles.

Anal Chem 2009 Feb;81(3):991-9

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.

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http://dx.doi.org/10.1021/ac802031jDOI Listing
February 2009

Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system.

Lab Chip 2009 Jan 27;9(1):38-40. Epub 2008 Oct 27.

Interdisciplinary Program in Bioengineering, Georgia Institute of Technology, Atlanta, GA, USA.

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http://www.lulab.gatech.edu/wp-content/uploads/2009/05/b8137
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http://xlink.rsc.org/?DOI=B813730G
Publisher Site
http://dx.doi.org/10.1039/b813730gDOI Listing
January 2009

Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans.

Nat Methods 2008 Jul 22;5(7):637-43. Epub 2008 Jun 22.

School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr. NW, Atlanta, Georgia 30332, USA.

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http://dx.doi.org/10.1038/nmeth.1227DOI Listing
July 2008

How does dextran sulfate prevent heat induced aggregation of protein? The mechanism and its limitation as aggregation inhibitor.

Biochim Biophys Acta 2007 Feb 6;1774(2):249-57. Epub 2006 Dec 6.

School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea.

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http://linkinghub.elsevier.com/retrieve/pii/S157096390600408
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http://dx.doi.org/10.1016/j.bbapap.2006.11.015DOI Listing
February 2007