Kurt Zatloukal

Kurt Zatloukal

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Kurt Zatloukal

Kurt Zatloukal

Publications by authors named "Kurt Zatloukal"

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Limiting factors for wearing personal protective equipment (PPE) in a health care environment evaluated in a randomised study.

PLoS One 2019 22;14(1):e0210775. Epub 2019 Jan 22.

Medical University Graz, Institute of Pathology, Christian Doppler Laboratory for Biospecimen Research and Biobanking Technologies, Graz, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210775PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342303PMC
November 2019

The impact of crosslinking and non-crosslinking fixatives on antigen retrieval and immunohistochemistry.

N Biotechnol 2019 Sep 11;52:69-83. Epub 2019 May 11.

Diagnostic- and Research Center for Molecular Biomedicine, Institute of Pathology, Medical University of Graz, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.nbt.2019.05.003DOI Listing
September 2019

Pre-analytical processes in medical diagnostics: New regulatory requirements and standards.

N Biotechnol 2019 Sep 15;52:121-125. Epub 2019 May 15.

Diagnostic- and Research Center for Molecular Biomedicine, Inst. of Pathology, Medical University of Graz, Neue Stiftingtalstr. 6, 8010 Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.nbt.2019.05.002DOI Listing
September 2019

Animal models of NAFLD from the pathologist's point of view.

Biochim Biophys Acta Mol Basis Dis 2019 May 8;1865(5):929-942. Epub 2018 May 8.

Institute of Pathology, Medical University of Graz, Neue Stiftingtalstraße 6, A-8010 Graz, Austria.

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http://dx.doi.org/10.1016/j.bbadis.2018.04.024DOI Listing
May 2019

Role of Academic Biobanks in Public-Private Partnerships in the European Biobanking and BioMolecular Resources Research Infrastructure Community.

Biopreserv Biobank 2019 30;17(1):46-51. Epub 2018 Nov 30.

5 Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1089/bio.2018.0024DOI Listing
May 2019

Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma.

Expert Opin Ther Targets 2019 May 15;23(5):393-406. Epub 2019 Apr 15.

a Institute of Pathology , Medical University of Graz , Graz , Austria.

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https://www.tandfonline.com/doi/full/10.1080/14728222.2019.1
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http://dx.doi.org/10.1080/14728222.2019.1601703DOI Listing
May 2019

Transnational access to large prospective cohorts in Europe: Current trends and unmet needs.

N Biotechnol 2019 Mar 17;49:98-103. Epub 2018 Oct 17.

Institute for Molecular Medicine Finland FIMM, University of Helsinki, Biomedicum 2U, Tukholmankati 8, 00290, Helsinki, Finland; National Institute for Health and Welfare (THL), Biomedicum 1, Haartmaninkatu 8, 00290, Helsinki, Finland; University of Tartu, Estonian Genome Center, Riia 23b, 51010, Tartu, Estonia.

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https://linkinghub.elsevier.com/retrieve/pii/S18716784183177
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http://dx.doi.org/10.1016/j.nbt.2018.10.001DOI Listing
March 2019

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

Hepatology 2018 09 1;68(3):933-948. Epub 2018 Feb 1.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.29679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175233PMC
September 2018

Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.

Stem Cell Res 2018 08 25;31:113-116. Epub 2018 Jul 25.

Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.015DOI Listing
August 2018

Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype.

Stem Cell Res 2018 08 27;31:131-134. Epub 2018 Jul 27.

Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.011DOI Listing
August 2018

Bringing the cell nucleus in the focus of NAFLD.

Authors:
Kurt Zatloukal

Hepatology 2018 05 26;67(5):1654-1656. Epub 2018 Mar 26.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.29696DOI Listing
May 2018

Machine learning enhanced virtual autopsy.

Autops Case Rep 2017 Oct-Dec;7(4):3-7. Epub 2017 Dec 8.

University Hospital Hamburg Eppendorf, Department of Intensive Care. Hamburg, Germany.

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http://dx.doi.org/10.4322/acr.2017.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724048PMC
December 2017

Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation.

J Vis Exp 2017 12 25(130). Epub 2017 Dec 25.

Christian Doppler Laboratory for Biospecimen Research and Biobanking Technologies, Institute of Pathology, Medical University Graz; Institute of Pathology, Medical University Graz;

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http://dx.doi.org/10.3791/55885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908343PMC
December 2017

From the evaluation of existing solutions to an all-inclusive package for biobanks.

Health Technol (Berl) 2017 12;7(1):89-95. Epub 2017 Jan 12.

Institut national de la santé et de la recherche médicale, 75654 Paris, France.

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http://dx.doi.org/10.1007/s12553-016-0175-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346419PMC
January 2017

A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.

Nat Commun 2016 12 21;7:13781. Epub 2016 Dec 21.

Department of Microbiology, Immune biology, and Genetics, Center for Molecular Biology, University of Vienna-Max F. Perutz Laboratories, Doktor-Bohr-Gasse 9, Vienna 1030, Austria.

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http://dx.doi.org/10.1038/ncomms13781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187498PMC
December 2016

Automatic classification of histopathological diagnoses for building a large scale tissue catalogue.

Health Technol (Berl) 2017 22;7(1):81-88. Epub 2016 Dec 22.

Medical University of Graz, A-8010 Graz, Austria.

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http://dx.doi.org/10.1007/s12553-016-0169-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346425PMC
December 2016

Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis.

Stem Cell Res 2016 11 20;17(3):547-549. Epub 2016 Oct 20.

Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.10.004DOI Listing
November 2016

Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis.

Stem Cell Res 2016 11 19;17(3):568-571. Epub 2016 Oct 19.

Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.10.007DOI Listing
November 2016

Characterization of iPSCs derived from dermal fibroblasts from a healthy 19year old female.

Stem Cell Res 2016 11 19;17(3):597-599. Epub 2016 Oct 19.

Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.10.002DOI Listing
November 2016

Immunofluorescence and Immunohistochemical Detection of Keratins.

Methods Enzymol 2016 24;568:139-62. Epub 2015 Oct 24.

Institute of Pathology, Medical University of Graz, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2015.08.003DOI Listing
October 2016

Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.

J Biol Chem 2016 09 20;291(36):18663-74. Epub 2016 Jun 20.

the Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas 66160,

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http://dx.doi.org/10.1074/jbc.M116.739821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009243PMC
September 2016

Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.

Cancer Cell Int 2016 6;16(1):68. Epub 2016 Sep 6.

Molecular Pathology Laboratory, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.1186/s12935-016-0343-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011867PMC
September 2016

Individual Human Metabolic Phenotype Analyzed by (1)H NMR of Saliva Samples.

J Proteome Res 2016 06 3;15(6):1787-93. Epub 2016 May 3.

Medical University Graz , Auenbruggerplatz 2, A-8036 Graz, Austria.

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http://dx.doi.org/10.1021/acs.jproteome.5b01060DOI Listing
June 2016

Protocol for HER2 FISH determination on PAXgene-fixed and paraffin-embedded tissue in breast cancer.

Int J Exp Pathol 2016 04 8;97(2):202-6. Epub 2016 Jun 8.

CD Laboratory for Biospecimen Research and Biobanking Technologies, Institute of Pathology, Medical University Graz, Graz, Austria.

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http://dx.doi.org/10.1111/iep.12185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926048PMC
April 2016

Alterations in Human Liver Metabolome during Prolonged Cryostorage.

J Proteome Res 2015 Jul 11;14(7):2758-68. Epub 2015 Jun 11.

†Institute of Pathology, Medical University of Graz, Austria Auenbruggerplatz 25, A-8036 Graz, Austria.

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http://dx.doi.org/10.1021/acs.jproteome.5b00025DOI Listing
July 2015

The impact of free or standardized lifestyle and urine sampling protocol on metabolome recognition accuracy.

Genes Nutr 2015 Jan 18;10(1):441. Epub 2014 Nov 18.

Center of Molecular Medicine, Institute of Pathophysiology and Immunology, Medical University Graz, Heinrichstraße 31a, 8010, Graz, Austria,

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http://dx.doi.org/10.1007/s12263-014-0441-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235801PMC
January 2015

Molecular mechanisms of endometrial stromal sarcoma and undifferentiated endometrial sarcoma as premises for new therapeutic strategies.

Cancer Lett 2014 Nov 13;354(1):21-7. Epub 2014 Aug 13.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1016/j.canlet.2014.08.013DOI Listing
November 2014

Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.

Anticancer Res 2014 Jun;34(6):2883-97

Institute of Pathology, Medical University of Graz, Graz, Austria

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June 2014

Public-private relationships in biobanking: a still underestimated key component of open innovation.

Virchows Arch 2014 Jan 14;464(1):3-9. Epub 2013 Dec 14.

Hospital-Integrated Tumor Biobank, Pasteur Hospital, Nice, France,

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http://dx.doi.org/10.1007/s00428-013-1524-zDOI Listing
January 2014

Effects of intra- and post-operative ischemia on the metabolic profile of clinical liver tissue specimens monitored by NMR.

J Proteome Res 2013 Dec 29;12(12):5723-9. Epub 2013 Oct 29.

CERM, University of Florence , Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1021/pr400702dDOI Listing
December 2013

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

BMC Med Genomics 2013 Nov 8;6:50. Epub 2013 Nov 8.

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, BMC, Uppsala University, PO BOX 815, Uppsala, SE 751 08, Sweden.

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http://dx.doi.org/10.1186/1755-8794-6-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831757PMC
November 2013

Inactivation of Influenza A virus, Adenovirus, and Cytomegalovirus with PAXgene tissue fixative and formalin.

Biopreserv Biobank 2013 Aug;11(4):229-34

1 Department of Pathology, Josephine Nefkens Institute , Erasmus MC, Rotterdam, Netherlands .

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http://dx.doi.org/10.1089/bio.2013.0010DOI Listing
August 2013

Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.

Nat Cell Biol 2012 Nov 7;14(11):1203-11. Epub 2012 Oct 7.

State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Yueyang Road 320, Shanghai 200031, China.

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http://www.nature.com/articles/ncb2590
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http://dx.doi.org/10.1038/ncb2590DOI Listing
November 2012

Insights into molecular mechanisms contributing to individual susceptibility to steatohepatitis: lessons learned from mouse models.

Authors:
Kurt Zatloukal

Hepatology 2012 Jun;55(6):2027-30

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.25707DOI Listing
June 2012

Safeguarding donors' personal rights and biobank autonomy in biobank networks: the CRIP privacy regime.

Cell Tissue Bank 2011 Aug 15;12(3):233-40. Epub 2010 Jul 15.

Fraunhofer Institut für Biomedizinische Technik, Am Mühlenberg 13, 14476, Potsdam-Golm, Germany.

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http://dx.doi.org/10.1007/s10561-010-9190-8DOI Listing
August 2011

Human tissue biobanks as instruments for drug discovery and development: impact on personalized medicine.

Biomark Med 2010 Dec;4(6):895-903

Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.2217/bmm.10.104DOI Listing
December 2010

Proteomic analysis of PAXgene-fixed tissues.

J Proteome Res 2010 Oct;9(10):5188-96

Institute of Pathology, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1021/pr100664eDOI Listing
October 2010

The role of the pathologist in tissue banking: European Consensus Expert Group Report.

Virchows Arch 2010 Apr 16;456(4):449-54. Epub 2010 Feb 16.

Division of Surgical, Molecular and Ultrastructural Pathology, University of Pisa and Pisa University Hospital, Medical School, via Roma 57, 56126 Pisa, Italy.

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http://dx.doi.org/10.1007/s00428-010-0887-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852521PMC
April 2010

Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo.

Mol Cancer 2010 Mar 4;9:49. Epub 2010 Mar 4.

Lore Saldow Research Unit for Molecular Pathology of Gynecologic Tumors, Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.1186/1476-4598-9-49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843655PMC
March 2010

Caleydo: connecting pathways and gene expression.

Bioinformatics 2009 Oct 20;25(20):2760-1. Epub 2009 Jul 20.

Institute for Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16 and Institute of Pathology, Medical University Graz, Auenbruggerplatz 25, 8010 Graz, Austria.

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http://dx.doi.org/10.1093/bioinformatics/btp432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759551PMC
October 2009

The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.

Hepatology 2009 Sep;50(3):893-9

Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.23068DOI Listing
September 2009

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer.

Breast Cancer Res Treat 2009 Jul 1;116(1):69-77. Epub 2008 Jul 1.

Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10549-008-0105-3DOI Listing
July 2009

miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis.

EMBO Rep 2009 Apr 27;10(4):400-5. Epub 2009 Feb 27.

IMBA Vienna, Institute for Molecular Pathology, Dr Bohrgasse 3-5, 1030 Vienna, Austria.

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http://dx.doi.org/10.1038/embor.2009.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672883PMC
April 2009

Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis.

J Hepatol 2008 May 22;48(5):821-8. Epub 2008 Feb 22.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, Graz, Austria.

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http://dx.doi.org/10.1016/j.jhep.2008.01.026DOI Listing
May 2008

Biobanking for Europe.

Brief Bioinform 2008 Jan 23;9(1):14-24. Epub 2007 Oct 23.

The University of Manchester, School of Translational Medicine, CIGMR Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/bib/bbm050DOI Listing
January 2008

Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase.

Proc Natl Acad Sci U S A 2007 Oct 16;104(43):17105-10. Epub 2007 Oct 16.

Research Institute of Molecular Pathology, Doktor Bohr Gasse 7, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.0706272104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040484PMC
October 2007

Biobanks: transnational, European and global networks.

Brief Funct Genomic Proteomic 2007 Sep 4;6(3):193-201. Epub 2007 Oct 4.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A-8036 Graz, Austria.

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http://dx.doi.org/10.1093/bfgp/elm023DOI Listing
September 2007