Kurt Possinger

Kurt Possinger

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Kurt Possinger

Kurt Possinger

Publications by authors named "Kurt Possinger"

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Tumor Cell-selective Synergism of TRAIL- and ATRA-induced Cytotoxicity in Breast Cancer Cells.

Anticancer Res 2018 05;38(5):2669-2682

Department of Hematology and Oncology, Benjamin Franklin Campus, Charité University of Medicine Berlin, Berlin, Germany

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http://dx.doi.org/10.21873/anticanres.12509DOI Listing
May 2018

Pretreatment of BMSCs with TZD solution decreases the proliferation rate of MCF‑7 cells by reducing FGF4 protein expression.

Mol Med Rep 2016 Apr 2;13(4):3406-14. Epub 2016 Mar 2.

Division of Oncology and Haematology, Charité Campus Mitte, Humboldt University of Berlin, D‑10099 Berlin, Germany.

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http://dx.doi.org/10.3892/mmr.2016.4959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805074PMC
April 2016

Cisplatin Plus Ifosfamide with/without Etoposide as Salvage Treatment in Heavily-pre-treated Patients with Metastatic Breast Cancer.

Anticancer Res 2015 Sep;35(9):5091-5

Department of Hematology and Oncology, Charité Campus Mitte, Charité-University Medicine Berlin, Berlin, Germany.

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http://ar.iiarjournals.org/content/35/9/5091.full.pdf
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September 2015

Treatment of primary breast cancer at the surgical unit of the Charité 1984-1998.

Onkologie 2013 22;36(12):727-36. Epub 2013 Nov 22.

Brustzentrum Charité, Medizinische Klinik und Poliklinik, Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1159/000356805DOI Listing
August 2014

Concurrent inhibition of PI3-kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.

Cancer Lett 2013 Oct 27;339(2):288-97. Epub 2012 Nov 27.

Charité-Universitätsmedizin Berlin, Department of Oncology and Hematology, Berlin, Germany.

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http://dx.doi.org/10.1016/j.canlet.2012.11.013DOI Listing
October 2013

Influence of CYP2D6-genotype on tamoxifen efficacy in advanced breast cancer.

Breast Cancer Res Treat 2013 Jun 18;139(2):553-60. Epub 2013 May 18.

Department of Oncology and Hematology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s10549-013-2565-3DOI Listing
June 2013

The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial.

Anticancer Res 2012 Aug;32(8):3435-41

Department of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Charitéplatz 1,10117 Berlin, Germany.

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August 2012

5FU continuous infusion in heavily pretreated advanced breast cancer patients.

Onkologie 2011 21;34(12):696-700. Epub 2011 Nov 21.

Department of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Gremany.

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http://dx.doi.org/10.1159/000334550DOI Listing
April 2012

Breast Cancer-Associated Thrombotic Microangiopathy.

Breast Care (Basel) 2011 Dec 15;6(6):441-445. Epub 2011 Dec 15.

Department of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Struensee-Haus, Hamburg, Germany.

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http://dx.doi.org/10.1159/000335201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290020PMC
December 2011

Effect of the tyrosine kinase inhibitor lapatinib on CUB-domain containing protein (CDCP1)-mediated breast cancer cell survival and migration.

Biochem Biophys Res Commun 2011 Oct 17;414(1):226-32. Epub 2011 Sep 17.

Charité Campus Mitte, Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Humboldt Universität zu Berlin, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2011.09.062DOI Listing
October 2011

Simultaneous Inhibition of Estrogen Receptor and the HER2 Pathway in Breast Cancer: Effects of HER2 Abundance.

Transl Oncol 2011 Oct 1;4(5):293-300. Epub 2011 Oct 1.

Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162304PMC
http://dx.doi.org/10.1593/tlo.11127DOI Listing
October 2011

The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.

Anticancer Res 2011 Sep;31(9):2713-22

Division of Oncology and Hematology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. and

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September 2011

Association of IL-6, hypothalamus-pituitary-adrenal axis function, and depression in patients with cancer.

Integr Cancer Ther 2010 Sep 11;9(3):270-5. Epub 2010 May 11.

Department of Oncology and Hematology, University Hospital Charité, Berlin, Germany.

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http://dx.doi.org/10.1177/1534735410370036DOI Listing
September 2010

Therapeutic implication of BAL in patients with neutropenia.

Ann Hematol 2009 Dec 5;88(12):1249-56. Epub 2009 May 5.

Department of Oncology and Hematology, University Hospital Charité, 10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s00277-009-0747-1DOI Listing
December 2009

Induction of endoplasmic reticulum stress response by TZD18, a novel dual ligand for peroxisome proliferator-activated receptor alpha/gamma, in human breast cancer cells.

Mol Cancer Ther 2009 Aug 11;8(8):2296-307. Epub 2009 Aug 11.

Division of Oncology/Hematology, Department of Hematology and Oncology, University Medicine Charité,Berlin, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-0347DOI Listing
August 2009

Compound 48, a novel dual PPAR alpha/gamma ligand, inhibits the growth of human CML cell lines and enhances the anticancer-effects of imatinib.

Leuk Res 2009 May 7;33(5):686-92. Epub 2009 Jan 7.

Division of Hematology/Oncology, Universitätsmedizin Berlin Charité, Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S014521260800525
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http://dx.doi.org/10.1016/j.leukres.2008.11.023DOI Listing
May 2009

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.

Eur J Pharmacol 2008 Sep 12;591(1-3):43-51. Epub 2008 Jun 12.

Department of Oncology and Hematology, University Hospital Charité, Humboldt University of Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ejphar.2008.06.026DOI Listing
September 2008

The effect of induced hyperthermia on the immune system.

Prog Brain Res 2007 ;162:137-52

Department of Oncology and Hematology, Charité Campus Mitte, University Medicine Berlin, Germany, Schumannstrasse 20/21, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1016/S0079-6123(06)62008-6DOI Listing
April 2008

Prescription pattern of aromatase inhibitors for the adjuvant therapy of breast cancer in Germany - results of the second survey among gynaecologists and medical oncologists.

Onkologie 2008 Feb 22;31(1-2):19-25. Epub 2008 Jan 22.

Medizinische Klinik und Poliklinik mit Schwerpunkt Onkologie und Hämatologie, Charité, Campus Mitte, Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1159/000111761DOI Listing
February 2008

Biomarkers of depression in cancer patients.

Cancer 2006 Dec;107(11):2723-9

Department of Oncology and Hematology, University Hospital Charite, Berlin, Germany.

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http://dx.doi.org/10.1002/cncr.22294DOI Listing
December 2006

Dual PPARalpha/gamma ligand TZD18 either alone or in combination with imatinib inhibits proliferation and induces apoptosis of human CML cell lines.

Cell Cycle 2006 Oct 1;5(19):2237-43. Epub 2006 Oct 1.

Division of Oncology/Hematology, Universitätsmedizin Berlin, Charité Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.4161/cc.5.19.3259DOI Listing
October 2006

Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18.

Blood 2006 May 10;107(9):3683-92. Epub 2006 Jan 10.

Division of Hematology/Oncology, School of Medicine Charité, Humboldt University, Schumannstrasse 20/21, 10117 Berlin, Germany.

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http://dx.doi.org/10.1182/blood-2005-05-2103DOI Listing
May 2006

Prescription pattern of aromatase inhibitors in the adjuvant setting in Germany--final results of a survey among german breast cancer specialists.

Onkologie 2005 Dec 1;28(12):639-44. Epub 2005 Dec 1.

Medizinische Klinik und Poliklinik II, Schwerpunkt Onkologie und Hämatologie, Universitätsmedizin Berlin, Charité, Humboldt-Universität zu Berlin, Germany.

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http://dx.doi.org/10.1159/000089339DOI Listing
December 2005

Pegfilgrastim -- rational drug design for the management of chemotherapy-induced neutropenia.

Onkologie 2005 Nov;28(11):595-602

Medizinische Klinik und Poliklinik II mit Schwerpunkt Onkologie und Hämatologie, Charité Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.1159/000088286DOI Listing
November 2005

Gemcitabine as prolonged infusion and vinorelbine in anthracycline and/or taxane pretreated metastatic breast cancer: a phase II study.

J Cancer Res Clin Oncol 2005 Sep 20;131(9):568-74. Epub 2005 Oct 20.

Berlin Breast Cancer Research Group, Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Charité Campus Mitte, Humboldt Universität zu Berlin, Berlin, Germany.

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http://link.springer.com/10.1007/s00432-005-0675-y
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http://dx.doi.org/10.1007/s00432-005-0675-yDOI Listing
September 2005

Gemcitabine and mitoxantrone in metastatic breast cancer: a phase-I-study.

Invest New Drugs 2005 Aug;23(4):349-56

Berlin Breast Cancer Research Group, Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Charité Campus Mitte, Humboldt Universität zu Berlin, Berlin, Germany.

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http://link.springer.com/10.1007/s10637-005-1443-1
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http://dx.doi.org/10.1007/s10637-005-1443-1DOI Listing
August 2005

Proteasome inhibitors abrogate osteoclast differentiation and osteoclast function.

Biochem Biophys Res Commun 2005 Jul;333(1):200-5

Department of Oncology and Hematology, University Hospital Charité, Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0501075
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http://dx.doi.org/10.1016/j.bbrc.2005.05.098DOI Listing
July 2005

Proteasome: an emerging target for cancer therapy.

Anticancer Drugs 2005 Jun;16(5):475-81

Department of Oncology and Hematology, University Hospital Charité, 10117 Berlin, Germany.

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http://dx.doi.org/10.1097/00001813-200506000-00002DOI Listing
June 2005

Prolonged infusion of gemcitabine in advanced solid tumors: a phase-I-study.

Invest New Drugs 2005 Mar;23(2):139-46

Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Charité Campus Mitte, Humboldt Universität zu Berlin, 10117 Berlin, Germany.

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http://link.springer.com/10.1007/s10637-005-5859-4
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http://dx.doi.org/10.1007/s10637-005-5859-4DOI Listing
March 2005

Up-front tandem high-dose chemotherapy compared with standard chemotherapy with doxorubicin and paclitaxel in metastatic breast cancer: results of a randomized trial.

J Clin Oncol 2005 Jan;23(3):432-40

Department of Oncology and Hematology, Charité Campus Mitte, Humboldt University Berlin, Schumannstrasse 20/21, 10117 Berlin, Germany.

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http://dx.doi.org/10.1200/JCO.2005.06.072DOI Listing
January 2005

Fulvestrant - a new treatment for postmenopausal women with hormone-sensitive advanced breast cancer.

Authors:
Kurt Possinger

Expert Opin Pharmacother 2004 Dec;5(12):2549-58

Universitätsmedizin, Department of Oncology and Haematology, Charité Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.1517/14656566.5.12.2549DOI Listing
December 2004

Lack of HER-2/neu overexpression in non-Hodgkin's lymphoma.

Anticancer Res 2004 Sep-Oct;24(5B):3233-7

Medizinische Klinik und Poliklinik II Schwerpunkt Onkologie und Hämatologie Universitätsmedizin Berlin, Charité, Campus Mitte, Humboldt-Universität zu Berlin, Schumannstr 20-21, 10117 Berlin, Germany.

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November 2004

Ligands of peroxisome proliferator-activated receptor gamma induce apoptosis in multiple myeloma.

Anticancer Drugs 2004 Nov;15(10):955-60

Department of Oncology and Hematology, University Hospital Charité, Berlin, Germany.

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http://dx.doi.org/10.1097/00001813-200411000-00004DOI Listing
November 2004

[Berlin Society of Internal Medicine].

Med Klin (Munich) 2004 Nov;99(11):684

Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Universitätsklinikum Charité Mitte, Berlin.

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http://dx.doi.org/10.1007/s00063-004-1102-xDOI Listing
November 2004

A novel PPAR alpha/gamma dual agonist inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.

Acta Pharmacol Sin 2004 Oct;25(10):1312-9

Division of Oncology/Hematology, School of Medicine (Charite, Humboldt University, 10117 Berlin, Germany.

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October 2004

Expression of receptor activator of NF-kappaB ligand (RANKL) mRNA in human multiple myeloma cells.

J Cancer Res Clin Oncol 2004 Aug 15;130(8):469-74. Epub 2004 Jun 15.

Department of Hematology and Oncology, Universitätsklinikum Charité, Humboldt-Universität Berlin, 10098 Berlin, Germany.

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http://dx.doi.org/10.1007/s00432-004-0578-3DOI Listing
August 2004

Serum HER-2/neu as a prediction and monitoring parameter in a phase II study with weekly paclitaxel in metastatic breast cancer.

Anticancer Res 2004 Mar-Apr;24(2B):895-906

Medizinische Klinik und Poliklinik II, Schwerpunkt Onkologie und Hämatologie, Universitätsklinikum Charité, Campus Mitte, Humboldt-Universität zu Berlin, 10117 Berlin, Germany.

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July 2004

Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists.

Pharmacogenetics 2004 May;14(5):271-8

Institute of Clinical Pharmacology, University Medical Center Charité, Humboldt University of Berlin, D-10098 Berlin, Germany.

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May 2004

Peroxisome proliferator-activated receptor gamma ligands induce growth inhibition and apoptosis of human B lymphocytic leukemia.

Leuk Res 2004 Apr;28(4):387-97

Division of Oncology/Hematology, School of Medicine (Charité), Humboldt University, Schumannstr. 20/21, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.leukres.2003.07.005DOI Listing
April 2004

Identification of clinically relevant yeasts by PCR/RFLP.

J Microbiol Methods 2004 Feb;56(2):201-11

Institute for Microbiology and Hygiene, Medical Faculty of Humboldt University, Charité, Dorotheenstr. 96, 10117 Berlin, Germany.

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February 2004

Liposomal daunorubicin (DaunoXome) in multiple myeloma: a modified VAD regimen using short-term infusion.

Anticancer Drugs 2003 Nov;14(10):793-9

Department of Oncology and Hematology, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Berlin, Germany.

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http://pdfs.journals.lww.com/anti-cancerdrugs/2003/11000/Lip
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http://dx.doi.org/10.1097/00001813-200311000-00004DOI Listing
November 2003

Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion.

J Cancer Res Clin Oncol 2003 Jul 8;129(7):383-91. Epub 2003 Jul 8.

Department of Oncology and Hematology, Universitätsklinikum Charité, Humboldt-Universität Berlin, 10098, Berlin, Germany.

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http://link.springer.com/10.1007/s00432-003-0454-6
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http://dx.doi.org/10.1007/s00432-003-0454-6DOI Listing
July 2003

Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients.

J Clin Oncol 2003 Jun;21(11):2147-55

Institute of Clinical Pharmacology and Department of Hematology and Oncology, University Medical Center Charité, Humboldt University of Berlin, Berlin, Germany.

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http://ascopubs.org/doi/10.1200/JCO.2003.05.164
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http://dx.doi.org/10.1200/JCO.2003.05.164DOI Listing
June 2003

Serum HER-2/neu in the management of breast cancer patients.

Clin Biochem 2003 Jun;36(4):233-40

Medizinische Klinik und Poliklinik II, Schwerpunkt Onkologie und Hämatologie, Universitätsklinikum Charité, Campus Mitte, Humboldt-Universität zu Berlin, Schumannstr 20-21, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/s0009-9120(03)00026-2DOI Listing
June 2003

Interactions of antioestrogens and aromatase inhibitors.

Forum (Genova) 2002 ;12(1):45-59

Department of Oncology and Hematology, Charité Campus Mitte, Humboldt University Berlin, Germany.

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April 2003

Bone marrow angiogenesis and its correlation with other disease characteristics in multiple myeloma in stage I versus stage II-III.

J Cancer Res Clin Oncol 2003 Apr 17;129(4):234-8. Epub 2003 Apr 17.

Department of Oncology and Hematology, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, 10098, Berlin, Germany.

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http://dx.doi.org/10.1007/s00432-003-0432-zDOI Listing
April 2003

[Bleeding breast cancer - a rare cause of anemia in males].

Med Klin (Munich) 2002 Dec;97(12):754-5

Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Universitätsklinikum Charité der (Campus Mitte) der Humboldt-Universität zu Berlin.

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December 2002

[High-dose chemotherapy in breast cancer].

Med Klin (Munich) 2002 Nov;97(11):677-86

Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Charite Campus Mitte, Humboldt-Universität Berlin, Germany.

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http://dx.doi.org/10.1007/s00063-002-1211-3DOI Listing
November 2002

The combination of fludarabine and cyclophosphamide results in a high remission rate with moderate toxicity in low-grade non-Hodgkin's lymphomas.

Anticancer Drugs 2002 Oct;13(9):907-13

Department of Hematology and Oncology, Universitätsklinikum Charité, Campus Mitte, Humboldt-Universität zu Berlin, 10098 Berlin, Germany.

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http://dx.doi.org/10.1097/00001813-200210000-00002DOI Listing
October 2002

Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes.

J Clin Oncol 2002 Jun;20(12):2805-11

Institute of Clinical Pharmacology and Department of Hematology and Oncology, University Medical Center Charité, Humboldt University of Berlin, Berlin, Germany.

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http://ascopubs.org/doi/10.1200/JCO.2002.09.064
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http://dx.doi.org/10.1200/JCO.2002.09.064DOI Listing
June 2002

Nuclear matrix proteins as biomarkers for breast cancer.

Expert Rev Mol Diagn 2002 Jan;2(1):23-31

Medizinische Klinik and Poliklinik II, Charite, Campus mitte, Schumannster 20-21, 10117 Berlin, Germany.

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http://dx.doi.org/10.1586/14737159.2.1.23DOI Listing
January 2002