Publications by authors named "Kurt J De Vos"

30Publications

Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.

Hum Mol Genet 2017 12;26(23):4668-4679

Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.

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https://academic.oup.com/hmg/article/26/23/4668/4158140
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http://dx.doi.org/10.1093/hmg/ddx348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886184PMC
December 2017

The role of mitochondria in amyotrophic lateral sclerosis.

Neurosci Lett 2019 09 30;710:132933. Epub 2017 Jun 30.

Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, S10 2HQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2017.06.052DOI Listing
September 2019

Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Front Mol Neurosci 2017 2;10:123. Epub 2017 May 2.

Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of SheffieldSheffield, UK.

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http://dx.doi.org/10.3389/fnmol.2017.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411428PMC
May 2017

Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?

Neurobiol Dis 2017 Sep 22;105:283-299. Epub 2017 Feb 22.

Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2017.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536153PMC
September 2017

C9orf72 plays a central role in Rab GTPase-dependent regulation of autophagy.

Small GTPases 2018 09 21;9(5):399-408. Epub 2016 Oct 21.

a Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience , University of Sheffield , Sheffield , UK.

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http://dx.doi.org/10.1080/21541248.2016.1240495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997165PMC
September 2018

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.

Neurobiol Dis 2016 Jan 11;85:1-10. Epub 2015 Oct 11.

King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, London, SE5 9NU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684147PMC
January 2016

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations.

Nat Commun 2014 Oct 15;5:5245. Epub 2014 Oct 15.

1] Centre for Membrane Interactions and Dynamics, University of Sheffield, Sheffield S10 2TN, UK [2] Department of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield S10 2HQ, UK.

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http://www.nature.com/articles/ncomms6245
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http://dx.doi.org/10.1038/ncomms6245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208097PMC
October 2014

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Nat Commun 2014 Jun 3;5:3996. Epub 2014 Jun 3.

1] Department of Neuroscience, Institute of Psychiatry, Kings College London, London SE5 8AF, UK [2] Clinical Neurosciences, Institute of Psychiatry, Kings College London, London SE5 8AF, UK.

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http://dx.doi.org/10.1038/ncomms4996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046113PMC
June 2014

Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish.

PLoS One 2013 26;8(6):e67276. Epub 2013 Jun 26.

Department of Neuroscience, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, United Kingdom ; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067276PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694133PMC
October 2017

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis.

Hum Mol Genet 2012 Mar 30;21(6):1299-311. Epub 2011 Nov 30.

Department of Neuroscience, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King’s College London, London SE5 8AF, UK.

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http://dx.doi.org/10.1093/hmg/ddr559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284118PMC
March 2012

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.

J Cell Sci 2011 Apr 8;124(Pt 7):1032-42. Epub 2011 Mar 8.

MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King's College London, PO Box 37, De Crespigny Park, Denmark Hill, London SE5 8AF, UK.

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http://dx.doi.org/10.1242/jcs.075168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056604PMC
April 2011

Deficiency of the copper chaperone for superoxide dismutase increases amyloid-β production.

J Alzheimers Dis 2010 ;21(4):1101-5

MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King's College London, UK.

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http://dx.doi.org/10.3233/JAD-2010-100717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023902PMC
January 2012

Riluzole protects against glutamate-induced slowing of neurofilament axonal transport.

Neurosci Lett 2009 Apr 3;454(2):161-4. Epub 2009 Mar 3.

MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King's College, London, UK.

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http://dx.doi.org/10.1016/j.neulet.2009.02.061DOI Listing
April 2009

Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments.

Eur J Cell Biol 2009 Apr 14;88(4):193-202. Epub 2009 Jan 14.

MRC Centre for Neurodegeneration Research, Department of Neuroscience P037, Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London SE58AF, UK.

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http://dx.doi.org/10.1016/j.ejcb.2008.11.004DOI Listing
April 2009

Role of axonal transport in neurodegenerative diseases.

Annu Rev Neurosci 2008 ;31:151-73

MRC Center for Neurodegeneration Research, Institute of Psychiatry, King's College, London SE5 8AF, United Kingdom.

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http://www.annualreviews.org/doi/10.1146/annurev.neuro.31.06
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http://dx.doi.org/10.1146/annurev.neuro.31.061307.090711DOI Listing
September 2008

Cell-free assays for mitochondria-cytoskeleton interactions.

Methods Cell Biol 2007 ;80:683-706

Department of Anatomy and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/S0091-679X(06)80031-2DOI Listing
June 2007

Visualization and quantification of mitochondrial dynamics in living animal cells.

Methods Cell Biol 2007 ;80:627-82

Department of Neuroscience, MRC Centre for Neurodegeneration Research, The Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London, United Kingdom.

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http://dx.doi.org/10.1016/S0091-679X(06)80030-0DOI Listing
June 2007

Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission.

Curr Biol 2005 Apr;15(7):678-83

Academic Unit of Neurology, Division of Genomic Medicine, School of Medicine and Biomedical Science, University of Sheffield, Sheffield S10 2RX, United Kingdom.

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http://dx.doi.org/10.1016/j.cub.2005.02.064DOI Listing
April 2005

Expression of phosphatidylinositol (4,5) bisphosphate-specific pleckstrin homology domains alters direction but not the level of axonal transport of mitochondria.

Mol Biol Cell 2003 Sep 11;14(9):3636-49. Epub 2003 Jul 11.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1091/mbc.e02-10-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC196556PMC
September 2003