Kuresh A Youdim

Kuresh A Youdim

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Kuresh A Youdim

Kuresh A Youdim

Publications by authors named "Kuresh A Youdim"

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14Publications

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Potential application of D-optimal designs in the efficient investigation of cytochrome P450 inhibition kinetic models.

Drug Metab Dispos 2010 Jul 16;38(7):1019-23. Epub 2010 Apr 16.

Pfizer Global Research and Development, Sandwich, Kent, United Kingdom.

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http://dx.doi.org/10.1124/dmd.110.033142DOI Listing
July 2010

A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 May 17;878(17-18):1326-36. Epub 2010 Feb 17.

Pfizer Global Research and Development, Pharmacokinetics Dynamics and Metabolism, Sandwich, Kent CT13 9NJ, UK.

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http://dx.doi.org/10.1016/j.jchromb.2010.02.013DOI Listing
May 2010

An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.

J Pharm Biomed Anal 2008 Sep 17;48(1):92-9. Epub 2008 May 17.

Pfizer Global Research and Development, Pharmacokinetics Dynamic and Metabolism, Sandwich, Kent, UK CT13 9NJ, United Kingdom.

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http://dx.doi.org/10.1016/j.jpba.2008.05.011DOI Listing
September 2008

Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay.

Drug Metab Dispos 2007 Feb 15;35(2):275-82. Epub 2006 Nov 15.

Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Sandwich, Kent, UK.

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http://dx.doi.org/10.1124/dmd.106.012864DOI Listing
February 2007

Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system.

Free Radic Biol Med 2004 Dec;37(11):1683-93

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, Guy's King's and St. Thomas's School of Biomedical Sciences, King's College, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2004.08.002DOI Listing
December 2004

Flavonoid permeability across an in situ model of the blood-brain barrier.

Free Radic Biol Med 2004 Mar;36(5):592-604

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, Centre for Neuroscience Research, Guy's King's and St Thomas's School of Biomedical Sciences, King's College, London SE1 1UL, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490300765
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http://dx.doi.org/10.1016/j.freeradbiomed.2003.11.023DOI Listing
March 2004

In vitro trans-monolayer permeability calculations: often forgotten assumptions.

Drug Discov Today 2003 Nov;8(21):997-1003

Antioxidant Research Group Wolfson Centre for Age-Related Diseases Guy's, King's and St Thomas' School of Biomedical Sciences King's College, London, SE1 1UL, UK.

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http://dx.doi.org/10.1016/s1359-6446(03)02873-3DOI Listing
November 2003

Interaction between flavonoids and the blood-brain barrier: in vitro studies.

J Neurochem 2003 Apr;85(1):180-92

Antioxidant Research Group, Wolfson Center for Age-Related Diseases, Centre for Neuroscience Research, Guy's, King's and St Thomas's School of Biomedical Sciences, King's College, London, UK.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01652.xDOI Listing
April 2003

Dietary flavonoids as potential neuroprotectants.

Biol Chem 2002 Mar-Apr;383(3-4):503-19

Wolfson Center for Age-Related Diseases, Guy's King's and St. Thomas's School of Biomedical Sciences, King's College, London, UK.

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http://dx.doi.org/10.1515/BC.2002.052DOI Listing
November 2002

Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults ( small star, filled).

J Nutr Biochem 2002 May;13(5):282-288

Human Nutrition Research Center on Aging at Tufts University, United States Department of Agriculture, 711 Washington Street, 02111, Boston, MA, USA

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http://dx.doi.org/10.1016/s0955-2863(01)00221-2DOI Listing
May 2002

Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits.

Ann N Y Acad Sci 2002 Apr;959:128-32

USDA-ARS, HNRCA at Tufts University, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb02089.xDOI Listing
April 2002