Publications



Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors.
Gastroenterology 2016 Jul 18;151(1):140-51. Epub 2016 Mar 18.
Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland. Electronic address:

Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes.
PLoS Genet 2015 30;11(9):e1005528. Epub 2015 Sep 30.
Department of Biological Chemistry, University of California, Irvine, Irvine, California, United States of America; Institute for Genomics and Bioinformatics, University of California, Irvine, Irvine, California, United States of America.

Activated platelet-T-cell conjugates in peripheral blood of patients with HIV infection: coupling coagulation/inflammation and T cells.
AIDS 2015 Jul;29(11):1297-308
aCMRS/Laboratory of Immunoregulation bResearch Technology Branch, NIAID, NIH, Bethesda cElectron Microscopy Laboratory, Cancer Research Technology Program dLaboratory of Human Retrovirology, Leidos Biomedical Research, Inc. Frederick eLaboratory of Pathology, NCI, NIH fBiostatistics Research Branch, DCR, NIAID, NIH, Bethesda gAIDS Monitoring Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, USA.

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
Proc Natl Acad Sci U S A 2015 Mar 16;112(13):E1624-31. Epub 2015 Mar 16.
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702

Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Hum Mol Genet 2014 Nov 6;23(21):5706-19. Epub 2014 Jun 6.
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA,




An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity.
Cell Rep 2013 Dec 27;5(5):1243-55. Epub 2013 Nov 27.
Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21701, USA. Electronic address:

Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.
Proc Natl Acad Sci U S A 2013 May 13;110(22):9078-83. Epub 2013 May 13.
Department of Microbiology, Abramson Cancer Center and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19103, USA.

Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116.
Cell Rep 2013 May 16;3(5):1457-64. Epub 2013 May 16.
Tumor Angiogenesis Section, Mouse Cancer Genetics Program (MCGP), Center for Cancer Research (CCR), National Cancer Institute (NCI), Frederick, MD 21702, USA.

Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
PLoS One 2012 3;7(8):e41401. Epub 2012 Aug 3.
Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.

Thyroid regeneration: characterization of clear cells after partial thyroidectomy.
Endocrinology 2012 May 27;153(5):2514-25. Epub 2012 Mar 27.
Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Budding of retroviruses utilizing divergent L domains requires nucleocapsid.
J Virol 2012 Apr 15;86(8):4182-93. Epub 2012 Feb 15.
Laboratory of Molecular Microbiology, Virus Budding Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Innate immunity against Granulibacter bethesdensis, an emerging gram-negative bacterial pathogen.
Infect Immun 2012 Mar 19;80(3):975-81. Epub 2011 Dec 19.
Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.



The interdomain linker region of HIV-1 capsid protein is a critical determinant of proper core assembly and stability.
Virology 2011 Dec 26;421(2):253-65. Epub 2011 Oct 26.
Section on Viral Gene Regulation, Program in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health, National Institutes of Health, Bethesda, MD 20892-2780, USA.

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.
Proc Natl Acad Sci U S A 2011 Apr 18;108(14):5759-64. Epub 2011 Mar 18.
Tumor Angiogenesis Section, Mouse Cancer Genetics Program, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.

The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy.
PLoS One 2011 Jan 31;6(1):e14640. Epub 2011 Jan 31.
Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
Toxicol Sci 2010 Nov 11;118(1):191-201. Epub 2010 Aug 11.
Carcinogen-DNA Interactions Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4255, USA.

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.
Proc Natl Acad Sci U S A 2010 Jul 12;107(30):13336-41. Epub 2010 Jul 12.
Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction.
Proc Natl Acad Sci U S A 2009 Nov 5;106(47):20063-8. Epub 2009 Nov 5.
Program in Gene Function and Expression and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.


The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral budding.
PLoS Pathog 2009 Mar 13;5(3):e1000339. Epub 2009 Mar 13.
Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J Mol Biol 2008 Oct 16;382(2):434-47. Epub 2008 Jul 16.
Howard Hughes Medical Institute, Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease.
Inflamm Bowel Dis 2008 Jul;14(7):908-20
Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation.
Toxicol Appl Pharmacol 2008 May 8;228(3):351-63. Epub 2008 Jan 8.
Laboratory of Cancer Prevention, Basic Research Program, SAIC-Frederick, Inc., National Cancer Institute-Frederick, Frederick, MD 21702, USA.

Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age.
Toxicol Sci 2007 Sep 1;99(1):203-13. Epub 2007 Jun 1.
Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Drive, Bethesda, Maryland 20892-4255, USA.


A second-site suppressor significantly improves the defective phenotype imposed by mutation of an aromatic residue in the N-terminal domain of the HIV-1 capsid protein.
Virology 2007 Mar 19;359(1):105-15. Epub 2006 Oct 19.
Viral Gene Regulation Section, Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Building 6B, Room 216, Bethesda, MD 20892-2780, USA.

In vitro resistance to the human immunodeficiency virus type 1 maturation inhibitor PA-457 (Bevirimat).
J Virol 2006 Nov 6;80(22):10957-71. Epub 2006 Sep 6.
Virus-Cell Interaction Section, HIV Drug Resistance Program, NCI-Frederick, Bldg. 535/Rm. 108, 1050 Boyles Street, Frederick, MD 21702-1201, USA.



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