Kun-Chieh Chen

Kun-Chieh Chen

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Kun-Chieh Chen

Kun-Chieh Chen

Publications by authors named "Kun-Chieh Chen"

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Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2019 Jul 12. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
July 2019

Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of SLAN.

Am J Physiol Cell Physiol 2019 Jul 17. Epub 2019 Jul 17.

Department of Applied Chemistry, Graduate Institute of Biomedicine and Biomedical Technology, National Chi Nan University, Taiwan.

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http://dx.doi.org/10.1152/ajpcell.00032.2019DOI Listing
July 2019

The Relationship Between Air Pollution and Lung Cancer in Nonsmokers in Taiwan.

J Thorac Oncol 2019 May 18;14(5):784-792. Epub 2019 Jan 18.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193002
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http://dx.doi.org/10.1016/j.jtho.2018.12.033DOI Listing
May 2019

High PD-L1 expression correlates with primary resistance to EGFR-TKIs in treatment naïve advanced EGFR-mutant lung adenocarcinoma patients.

Lung Cancer 2019 01 20;127:37-43. Epub 2018 Nov 20.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan; Comprehensive Cancer Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183064
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http://dx.doi.org/10.1016/j.lungcan.2018.11.021DOI Listing
January 2019

Intercalated Treatment Following Rebiopsy Is Associated with a Shorter Progression-Free Survival of Osimertinib Treatment.

Cancer Res Treat 2018 Oct 11;50(4):1164-1174. Epub 2017 Dec 11.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

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http://e-crt.org/journal/view.php?doi=10.4143/crt.2017.460
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http://dx.doi.org/10.4143/crt.2017.460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192904PMC
October 2018

Transcriptional repression of Aurora-A gene by wild-type p53 through directly binding to its promoter with histone deacetylase 1 and mSin3a.

Int J Cancer 2018 01 25;142(1):92-108. Epub 2017 Sep 25.

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, Republic of China.

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http://dx.doi.org/10.1002/ijc.31035DOI Listing
January 2018

Predictive factors for EGFR-tyrosine kinase inhibitor retreatment in patients with EGFR-mutated non-small-cell lung cancer - A multicenter retrospective SEQUENCE study.

Lung Cancer 2017 02 14;104:58-64. Epub 2016 Dec 14.

Department of Chest Medicine, Taipei AVeterans General Hospital, School of Medicine, National Yang-Ming Medical University, and School of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.12.002DOI Listing
February 2017

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Authors:
Wei Jie Seow Keitaro Matsuo Chao Agnes Hsiung Kouya Shiraishi Minsun Song Hee Nam Kim Maria Pik Wong Yun-Chul Hong H Dean Hosgood Zhaoming Wang I-Shou Chang Jiu-Cun Wang Nilanjan Chatterjee Margaret Tucker Hu Wei Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Baosen Zhou Neil E Caporaso Demetrius Albanes Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Xiao-Ou Shu Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Michiaki Kubo Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Hiroshi Nokihara Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Zhihua Yin Jianxin Shi Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Tangchun Wu Fusheng Wei Jason Y Y Wong Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Victor Ho Fun Lee Wu-Chou Su Yuh-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Pan-Chyr Yang Hsien-Chih Lin Yong-Bing Xiang Adeline Seow Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Haixin Li Yu-Tang Gao Chen Wu Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Charles Lawrence Laurie Burdett Meredith Yeager Kevin B Jacobs Amy Hutchinson Sonja I Berndt Xingzhou He Wei Wu Junwen Wang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Alan Dart Loon Sihoe Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen John K C Chan Minjie Chu Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Yen-Li Lo Ying-Hsiang Chen Joseph F Fraumeni Jie Liu Taiki Yamaji Yang Yang Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Guoping Wu Li-Hsin Chien Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Dongxin Lin Kexin Chen Yi-Long Wu Maria Teresa Landi Hongbing Shen Nathaniel Rothman Takashi Kohno Stephen J Chanock Qing Lan

Hum Mol Genet 2017 01;26(2):454-465

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856088PMC
January 2017

Mechanisms underlying lung resistance-related protein (LRP)-mediated doxorubicin resistance of non-small cell lung cancer cells.

Chin J Physiol 2016 Dec;59(6):331-347

Department of Life Sciences, National Chung Hsing University, Taichung 40227, Taiwan, Republic of China.

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http://www.airitilibrary.com/Publication/alDetailedMesh?DocI
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http://dx.doi.org/10.4077/CJP.2016.BAF426DOI Listing
December 2016

Hypoxia can impair doxorubicin resistance of non-small cell lung cancer cells by inhibiting MRP1 and P-gp expression and boosting the chemosensitizing effects of MRP1 and P-gp blockers.

Cell Oncol (Dordr) 2016 Oct 15;39(5):411-433. Epub 2016 Jun 15.

Department of Life Sciences, National Chung Hsing University, 145, Hsing-Da Rd, Taichung, 40227, Taiwan.

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http://dx.doi.org/10.1007/s13402-016-0285-5DOI Listing
October 2016

Predilection of contralateral upper lung metastasis in upper lobe lung adenocarcinoma patients.

J Thorac Dis 2016 Jan;8(1):86-92

1 Division of Chest Medicine, 2 Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan ; 3 Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan ; 4 Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan ; 5 Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan ; 6 Institute of Statistical Science, Academia Sinica, Taipei, Taiwan ; 7 NTU Center for Genomic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan ; 8 Department of Pathology and Graduate Institute of Pathology, 9 Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan ; 10 Graduate Institute of Toxicology, National Taiwan University, Taipei, Taiwan ; 11 Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan ; 12 Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2016.01.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740126PMC
January 2016

Identification of five driver gene mutations in patients with treatment-naïve lung adenocarcinoma in Taiwan.

PLoS One 2015 19;10(3):e0120852. Epub 2015 Mar 19.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120852PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366385PMC
December 2015

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Authors:
Joshua N Sampson William A Wheeler Meredith Yeager Orestis Panagiotou Zhaoming Wang Sonja I Berndt Qing Lan Christian C Abnet Laufey T Amundadottir Jonine D Figueroa Maria Teresa Landi Lisa Mirabello Sharon A Savage Philip R Taylor Immaculata De Vivo Katherine A McGlynn Mark P Purdue Preetha Rajaraman Hans-Olov Adami Anders Ahlbom Demetrius Albanes Maria Fernanda Amary She-Juan An Ulrika Andersson Gerald Andriole Irene L Andrulis Emanuele Angelucci Stephen M Ansell Cecilia Arici Bruce K Armstrong Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Nikolaus Becker Yolanda Benavente Simone Benhamou Christine Berg David Van Den Berg Leslie Bernstein Kimberly A Bertrand Brenda M Birmann Amanda Black Heiner Boeing Paolo Boffetta Marie-Christine Boutron-Ruault Paige M Bracci Louise Brinton Angela R Brooks-Wilson H Bas Bueno-de-Mesquita Laurie Burdett Julie Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Alfredo Carrato Tania Carreon Angela Carta John K C Chan Ellen T Chang Gee-Chen Chang I-Shou Chang Jiang Chang Jenny Chang-Claude Chien-Jen Chen Chih-Yi Chen Chu Chen Chung-Hsing Chen Constance Chen Hongyan Chen Kexin Chen Kuan-Yu Chen Kun-Chieh Chen Ying Chen Ying-Hsiang Chen Yi-Song Chen Yuh-Min Chen Li-Hsin Chien María-Dolores Chirlaque Jin Eun Choi Yi Young Choi Wong-Ho Chow Charles C Chung Jacqueline Clavel Françoise Clavel-Chapelon Pierluigi Cocco Joanne S Colt Eva Comperat Lucia Conde Joseph M Connors David Conti Victoria K Cortessis Michelle Cotterchio Wendy Cozen Simon Crouch Marta Crous-Bou Olivier Cussenot Faith G Davis Ti Ding W Ryan Diver Miren Dorronsoro Laure Dossus Eric J Duell Maria Grazia Ennas Ralph L Erickson Maria Feychting Adrienne M Flanagan Lenka Foretova Joseph F Fraumeni Neal D Freedman Laura E Beane Freeman Charles Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina García-Closas Randy D Gascoyne Julie Gastier-Foster Mia M Gaudet J Michael Gaziano Carol Giffen Graham G Giles Edward Giovannucci Bengt Glimelius Michael Goggins Nalan Gokgoz Alisa M Goldstein Richard Gorlick Myron Gross Robert Grubb Jian Gu Peng Guan Marc Gunter Huan Guo Thomas M Habermann Christopher A Haiman Dina Halai Goran Hallmans Manal Hassan Claudia Hattinger Qincheng He Xingzhou He Kathy Helzlsouer Brian Henderson Roger Henriksson Henrik Hjalgrim Judith Hoffman-Bolton Chancellor Hohensee Theodore R Holford Elizabeth A Holly Yun-Chul Hong Robert N Hoover Pamela L Horn-Ross G M Monawar Hosain H Dean Hosgood Chin-Fu Hsiao Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang Jose-Maria Huerta Jen-Yu Hung Amy Hutchinson Peter D Inskip Rebecca D Jackson Eric J Jacobs Mazda Jenab Hyo-Sung Jeon Bu-Tian Ji Guangfu Jin Li Jin Christoffer Johansen Alison Johnson Yoo Jin Jung Rudolph Kaaks Aruna Kamineni Eleanor Kane Chang Hyun Kang Margaret R Karagas Rachel S Kelly Kay-Tee Khaw Christopher Kim Hee Nam Kim Jin Hee Kim Jun Suk Kim Yeul Hong Kim Young Tae Kim Young-Chul Kim Cari M Kitahara Alison P Klein Robert J Klein Manolis Kogevinas Takashi Kohno Laurence N Kolonel Charles Kooperberg Anne Kricker Vittorio Krogh Hideo Kunitoh Robert C Kurtz Sun-Seog Kweon Andrea LaCroix Charles Lawrence Fernando Lecanda Victor Ho Fun Lee Donghui Li Haixin Li Jihua Li Yao-Jen Li Yuqing Li Linda M Liao Mark Liebow Tracy Lightfoot Wei-Yen Lim Chien-Chung Lin Dongxin Lin Sara Lindstrom Martha S Linet Brian K Link Chenwei Liu Jianjun Liu Li Liu Börje Ljungberg Josep Lloreta Simonetta Di Lollo Daru Lu Eiluv Lund Nuria Malats Satu Mannisto Loic Le Marchand Neyssa Marina Giovanna Masala Giuseppe Mastrangelo Keitaro Matsuo Marc Maynadie James McKay Roberta McKean-Cowdin Mads Melbye Beatrice S Melin Dominique S Michaud Tetsuya Mitsudomi Alain Monnereau Rebecca Montalvan Lee E Moore Lotte Maxild Mortensen Alexandra Nieters Kari E North Anne J Novak Ann L Oberg Kenneth Offit In-Jae Oh Sara H Olson Domenico Palli William Pao In Kyu Park Jae Yong Park Kyong Hwa Park Ana Patiño-Garcia Sofia Pavanello Petra H M Peeters Reury-Perng Perng Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Ludmila Prokunina-Olsson Biyun Qian You-Lin Qiao Marco Rais Elio Riboli Jacques Riby Harvey A Risch Cosmeri Rizzato Rebecca Rodabough Eve Roman Morgan Roupret Avima M Ruder Silvia de Sanjose Ghislaine Scelo Alan Schned Fredrick Schumacher Kendra Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Veronica Wendy Setiawan Gianluca Severi Richard K Severson Tait D Shanafelt Hongbing Shen Wei Shen Min-Ho Shin Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesúmaga Alan Dart Loon Sihoe Christine F Skibola Alex Smith Martyn T Smith Melissa C Southey John J Spinelli Anthony Staines Meir Stampfer Marianna C Stern Victoria L Stevens Rachael S Stolzenberg-Solomon Jian Su Wu-Chou Su Malin Sund Jae Sook Sung Sook Whan Sung Wen Tan Wei Tang Adonina Tardón David Thomas Carrie A Thompson Lesley F Tinker Roberto Tirabosco Anne Tjønneland Ruth C Travis Dimitrios Trichopoulos Fang-Yu Tsai Ying-Huang Tsai Margaret Tucker Jenny Turner Claire M Vajdic Roel C H Vermeulen Danylo J Villano Paolo Vineis Jarmo Virtamo Kala Visvanathan Jean Wactawski-Wende Chaoyu Wang Chih-Liang Wang Jiu-Cun Wang Junwen Wang Fusheng Wei Elisabete Weiderpass George J Weiner Stephanie Weinstein Nicolas Wentzensen Emily White Thomas E Witzig Brian M Wolpin Maria Pik Wong Chen Wu Guoping Wu Junjie Wu Tangchun Wu Wei Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Ping Xu Pan-Chyr Yang Tsung-Ying Yang Yuanqing Ye Zhihua Yin Jun Yokota Ho-Il Yoon Chong-Jen Yu Herbert Yu Kai Yu Jian-Min Yuan Andrew Zelenetz Anne Zeleniuch-Jacquotte Xu-Chao Zhang Yawei Zhang Xueying Zhao Zhenhong Zhao Hong Zheng Tongzhang Zheng Wei Zheng Baosen Zhou Meng Zhu Mariagrazia Zucca Simina M Boca James R Cerhan Giovanni M Ferri Patricia Hartge Chao Agnes Hsiung Corrado Magnani Lucia Miligi Lindsay M Morton Karin E Smedby Lauren R Teras Joseph Vijai Sophia S Wang Paul Brennan Neil E Caporaso David J Hunter Peter Kraft Nathaniel Rothman Debra T Silverman Susan L Slager Stephen J Chanock Nilanjan Chatterjee

J Natl Cancer Inst 2015 Dec 12;107(12):djv279. Epub 2015 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JNS, OP, SIB, QL, CCA, LTA, JDF, MTL, LM, SAS, PRT, KAM, PR, DA, DB, BAB, AB, LBr, WHC, CCC, JSC, JFFJr, NDF, LEBF, MGC, AMG, RNH, NH, WH, PDI, BTJ, CK, CMK, LML, MSL, LEM, LPO, RSSS, WeiT, MT, CWa, SW, NW, KY, PH, LMM, NEC, NR, DTS, SJC, NC); Information Management Services, Silver Spring, MD (WAW, CG); Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD (MY, ZW, LBu, AH, CLi); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (IDV, KAB, BMB, CoC, MCB, CF, EG, SL, JP, MSt, DJH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (IDV, OA, KAB, CoC, MCB, EG, RSK, SL, JP, HDS, MSt, DTr, DJH, PK); Ontario Health Study, Toronto, Ontario, Canada (MPP); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (HOA, EWe); Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AA, MF); UCL Cancer Institute, London, UK (MFA, AMF, DH); Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK (MFA, AMF, DH, RT); Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (SJA, JS, YLW, XCZ); Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden (UA, RH, BSM); Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO (GAJr, RGIII); Litwin Centre for Cancer Genetics, University of Toronto, Ontario, Canada (ILA, NG, JSW); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (ILA, SG, NG, JSW); Hematology Unit, Ospedale Oncologico di Riferimento Regionale A. Businco, Cagliari, Italy (EA); Department of Medicin

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http://kooperberg.fhcrc.org/papers/2015sampson.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv27
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http://dx.doi.org/10.1093/jnci/djv279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806328PMC
December 2015

Divergent epidermal growth factor receptor mutation patterns between smokers and non-smokers with lung adenocarcinoma.

Lung Cancer 2015 Dec 9;90(3):472-6. Epub 2015 Oct 9.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, No.1650, Sect. 4, Taiwan Boulevard, Taichung 407, Taiwan, ROC; Faculty of Medicine, School of Medicine, National Yang-Ming University, No.155, Sec.2, Linong St., Taipei 112, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.09.024DOI Listing
December 2015

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia.

Authors:
Mitchell J Machiela Chao Agnes Hsiung Xiao-Ou Shu Wei Jie Seow Zhaoming Wang Keitaro Matsuo Yun-Chul Hong Adeline Seow Chen Wu H Dean Hosgood Kexin Chen Jiu-Cun Wang Wanqing Wen Richard Cawthon Nilanjan Chatterjee Wei Hu Neil E Caporaso Jae Yong Park Chien-Jen Chen Yeul Hong Kim Young Tae Kim Maria Teresa Landi Hongbing Shen Charles Lawrence Laurie Burdett Meredith Yeager I-Shou Chang Tetsuya Mitsudomi Hee Nam Kim Gee-Chen Chang Bryan A Bassig Margaret Tucker Fusheng Wei Zhihua Yin She-Juan An Biyun Qian Victor Ho Fun Lee Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Jin Hee Kim Yu-Tang Gao Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Amy Hutchinson Wen-Chang Wang Robert J Klein Charles C Chung In-Jae Oh Kuan-Yu Chen Sonja I Berndt Wei Wu Jiang Chang Xu-Chao Zhang Ming-Shyan Huang Hong Zheng Junwen Wang Xueying Zhao Yuqing Li Jin Eun Choi Wu-Chou Su Kyong Hwa Park Sook Whan Sung Yuh-Min Chen Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen William Pao Young-Chul Kim Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Jian Su Chih-Liang Wang Haixin Li Alan Dart Loon Sihoe Zhenhong Zhao Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Takashi Kohno Sun-Seog Kweon Chih-Yi Chen Roel C H Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Wong-Ho Chow Bu-Tian Ji John K C Chan Minjie Chu Yao-Jen Li Jun Yokota Jihua Li Hongyan Chen Yong-Bing Xiang Chong-Jen Yu Hideo Kunitoh Guoping Wu Li Jin Yen-Li Lo Kouya Shiraishi Ying-Hsiang Chen Hsien-Chih Lin Tangchun Wu Maria Pik Wong Yi-Long Wu Pan-Chyr Yang Baosen Zhou Min-Ho Shin Joseph F Fraumeni Wei Zheng Dongxin Lin Stephen J Chanock Nathaniel Rothman Qing Lan

Int J Cancer 2015 Jul 29;137(2):311-9. Epub 2014 Dec 29.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1002/ijc.29393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733320PMC
July 2015

R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability.

J Clin Oncol 2015 Jul 8;33(20):2303-10. Epub 2015 Jun 8.

Hsuan-Yu Chen, Yi-Chiung Hsu, Chi-Sheng Chang, Yu-Cheng Li, Hao Ho, Ya-Hsuan Chang, Shinsheng Yuan, Chia-Hsin Liu, Guan-I Wu, and Ker-Chau Li, Institute of Statistical Science, and Shi-Yi Yang, Hwai-I Yang, and Chien-Jen Chen, Genomics Research Center, Academia Sinica; Hsuan-Yu Chen, Sung-Liang Yu, Bing-Ching Ho, Kang-Yi Su, and Pin-Yen Hsu, College of Medicine; Hsuan-Yu Chen, College of Life Science; Sung-Liang Yu, Kang-Yi Su, and Pan-Chyr Yang, Center of Genomic Medicine; Huei-Wen Chen, Graduate Institute of Toxicology, National Taiwan University; Sung-Liang Yu, Chong-Jen Yu, Kuan-Yu Chen, and Pan-Chyr Yang, National Taiwan University Hospital; Yuh-Min Chen, Taipei Veterans General Hospital; Chung-Ping Hsu, Tsung-Ying Yang, and Gee-Chen Chang, School of Medicine, National Yang-Ming University; Mei-Hsuan Lee, Institute of Clinical Medicine, National Yang-Ming University, Taipei; Chih-Yi Chen, Chung Shan Medical University; Chung-Ping Hsu, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Jiun-Yi Hsia, Cheng-Yen Chuang, and Gee-Chen Chang, Taichung Veterans General Hospital; Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, and Jeremy J.W. Chen, Institute of Biomedical Sciences, National Chung-Hsing University; Gee-Chen Chang, Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung; Chao A. Hsiung, Institute of Population Health Sciences, National Health Research Institutes, Zhunan; Chih-Liang Wang, Chang Gung Memorial Hospital, Tao-Yuan; Ying-Huang Tsai, Chang-Gung Memorial Hospital, Chia-Yi; Ming-Shyan Huang, Kaohsiung Medical University Hospital, College of Medicine, Kaohsiung Medical University, Kaohsiung; Wu-Chou Su, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; and Ker-Chau Li, University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1200/JCO.2014.59.3590DOI Listing
July 2015

Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

PLoS One 2014 12;9(9):e107160. Epub 2014 Sep 12.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107160PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162576PMC
May 2015

Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma.

J Thorac Oncol 2015 Apr;10(4):603-10

*Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, ROC; †Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; ‡Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; §Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; ‖Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan, ROC; ¶Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; #Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, ROC; **Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; ††Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; ‡‡Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; §§Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC; ‖‖Center of Genomic Medicine, National Taiwan University, Taipei, Taiwan, ROC; and ¶¶Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.

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http://dx.doi.org/10.1097/JTO.0000000000000443DOI Listing
April 2015

Pemetrexed induces S-phase arrest and apoptosis via a deregulated activation of Akt signaling pathway.

PLoS One 2014 21;9(5):e97888. Epub 2014 May 21.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China; Institute of Biomedical Science, National Chung Hsing University, Taichung, Taiwan, Republic of China; Department of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097888PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029963PMC
January 2015

Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma.

Onco Targets Ther 2014 23;7:799-805. Epub 2014 May 23.

Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan ; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan ; School of Medicine, China Medical University, Taichung, Taiwan ; Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan ; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.2147/OTT.S62639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043805PMC
June 2014

Luteolin attenuates TGF-β1-induced epithelial-mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt-NF-κB-Snail pathway.

Life Sci 2013 Dec 17;93(24):924-33. Epub 2013 Oct 17.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.lfs.2013.10.004DOI Listing
December 2013

Pemetrexed induces both intrinsic and extrinsic apoptosis through ataxia telangiectasia mutated/p53-dependent and -independent signaling pathways.

Mol Carcinog 2013 Mar 15;52(3):183-94. Epub 2011 Nov 15.

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, Republic of China.

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http://doi.wiley.com/10.1002/mc.21842
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http://dx.doi.org/10.1002/mc.21842DOI Listing
March 2013

Gallic Acid Induces a Reactive Oxygen Species-Provoked c-Jun NH2-Terminal Kinase-Dependent Apoptosis in Lung Fibroblasts.

Evid Based Complement Alternat Med 2013 20;2013:613950. Epub 2013 Feb 20.

Graduate Institute of Natural Healing Sciences, Nanhua University, No. 55, Section 1, Nanhua Road, Zhongkeng, Dalin Township, Chiayi County 622, Taiwan.

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http://dx.doi.org/10.1155/2013/613950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590506PMC
March 2013

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

Authors:
Qing Lan Chao A Hsiung Keitaro Matsuo Yun-Chul Hong Adeline Seow Zhaoming Wang H Dean Hosgood Kexin Chen Jiu-Cun Wang Nilanjan Chatterjee Wei Hu Maria Pik Wong Wei Zheng Neil Caporaso Jae Yong Park Chien-Jen Chen Yeul Hong Kim Young Tae Kim Maria Teresa Landi Hongbing Shen Charles Lawrence Laurie Burdett Meredith Yeager Jeffrey Yuenger Kevin B Jacobs I-Shou Chang Tetsuya Mitsudomi Hee Nam Kim Gee-Chen Chang Bryan A Bassig Margaret Tucker Fusheng Wei Zhihua Yin Chen Wu She-Juan An Biyun Qian Victor Ho Fun Lee Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Jin Hee Kim Yu-Tang Gao Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Amy Hutchinson Wen-Chang Wang Robert Klein Charles C Chung In-Jae Oh Kuan-Yu Chen Sonja I Berndt Xingzhou He Wei Wu Jiang Chang Xu-Chao Zhang Ming-Shyan Huang Hong Zheng Junwen Wang Xueying Zhao Yuqing Li Jin Eun Choi Wu-Chou Su Kyong Hwa Park Sook Whan Sung Xiao-Ou Shu Yuh-Min Chen Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen William Pao Young-Chul Kim Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Jian Su Chih-Liang Wang Haixin Li Alan Dart Loon Sihoe Zhenhong Zhao Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Takashi Kohno Sun-Seog Kweon Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Wong-Ho Chow Bu-Tian Ji John K C Chan Minjie Chu Yao-Jen Li Jun Yokota Jihua Li Hongyan Chen Yong-Bing Xiang Chong-Jen Yu Hideo Kunitoh Guoping Wu Li Jin Yen-Li Lo Kouya Shiraishi Ying-Hsiang Chen Hsien-Chih Lin Tangchun Wu Yi-Long Wu Pan-Chyr Yang Baosen Zhou Min-Ho Shin Joseph F Fraumeni Dongxin Lin Stephen J Chanock Nathaniel Rothman

Nat Genet 2012 Dec 11;44(12):1330-5. Epub 2012 Nov 11.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/ng.2456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169232PMC
December 2012

Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia.

Hum Genet 2012 Jul 25;131(7):1197-203. Epub 2012 Feb 25.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., EPS 8118, MCS 7240, Bethesda, MD 20892-7240, USA.

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http://dx.doi.org/10.1007/s00439-012-1144-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875137PMC
July 2012

Retrospective study of erlotinib in patients with advanced squamous lung cancer.

Lung Cancer 2012 Jul 13;77(1):128-33. Epub 2012 Mar 13.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.lungcan.2012.02.012DOI Listing
July 2012

Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells.

Eur J Pharmacol 2011 Aug 8;663(1-3):17-26. Epub 2011 May 8.

Institute of Medical and Molecular Toxicology, Chung Shan Medical University, Taichung, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.ejphar.2011.04.057DOI Listing
August 2011

Good response to gefitinib in a lung adenocarcinoma harboring a heterozygous complex mutation of L833V and H835L in epidermal growth factor receptor gene.

J Clin Oncol 2011 Jun 21;29(16):e468-9. Epub 2011 Mar 21.

Taichung Veterans General Hospital and Chung Shan Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.1200/JCO.2010.33.5802DOI Listing
June 2011

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.

PLoS Genet 2010 Aug 5;6(8). Epub 2010 Aug 5.

Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.

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http://dx.doi.org/10.1371/journal.pgen.1001051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916850PMC
August 2010

Survival outcome and predictors of gefitinib antitumor activity in East Asian chemonaive patients with advanced nonsmall cell lung cancer.

Cancer 2006 Oct;107(8):1873-82

Department of Oncology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1002/cncr.22220DOI Listing
October 2006

Predictive factors of gefitinib antitumor activity in East Asian advanced non-small cell lung cancer patients.

J Thorac Oncol 2006 Jul;1(6):520-5

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

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July 2006

Activity of gefitinib in advanced non-small-cell lung cancer with very poor performance status.

Invest New Drugs 2005 Jan;23(1):73-7

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China.

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http://dx.doi.org/10.1023/B:DRUG.0000047108.39129.7cDOI Listing
January 2005