Dr. Kuladip Jana, M.S., Ph.D, Postdoc (USA) - Bose Institute - Principal Scientist

Dr. Kuladip Jana

M.S., Ph.D, Postdoc (USA)

Bose Institute

Principal Scientist

Calcutta, Bengal | India

Main Specialties: Endocrinology Diabetes & Metabolism, Hematology & Oncology, Medical Toxicology

Additional Specialties: Molecular Medicine

ORCID logohttps://orcid.org/0000-0003-4748-253X

Dr. Kuladip Jana, M.S., Ph.D, Postdoc (USA) - Bose Institute - Principal Scientist

Dr. Kuladip Jana

M.S., Ph.D, Postdoc (USA)

Introduction

Dr. Kuladip Jana, M.Sc., M.S., Ph.D., Post-doctorate (U.S.A.)
Dr. Kuladip Jana, M.Sc., M.S., Ph.D., Post-doctorate (USA) was born and brought up in West Bengal, India. Dr. Jana is presently serving as a Principal Scientist in the Division of Molecular Medicine and Scientist-In-Charge of the Centre for Translational Animal Research, Bose Institute, Kolkata, India. Dr. Jana was trained as a Post-doctoral Research Associate in Molecular Endocrinology and Reproduction in relation with Aging in Garrison Institute on Aging, Texas Tech University Health Sciences Centre, Texas, U.S.A. and in Vaccine development against Cholera and Typhoid in National Institute of Cholera & Enteric Diseases, Kolkata, India and also in the field of Molecular signalling regulating cell growth/survival and death/apoptosis in cancer cells in Saha Institute of Nuclear Physics, Kolkata after obtaining his M.S. and Ph.D. in Reproductive Medicine from W. B. University of Animal Sciences., Kolkata, India and Vidyasagar University, India. Presently, Dr. Jana's laboratory focusing on Translational Research in the diverse direction i.e. Natural flavonoids Induced Apoptosis in Cervical and Breast Cancer Cells: Role of ?- catenin and Wnt signalling, Molecular signalling of Protein kinase-D and ?-Catenin interaction in cancer progression, Ageing associated oxidative stress & testicular gametogenic and steroidogenic disorders: Ameliorating potential of natural antioxidants, Alzheimer's disease in relation with StAR gene expression and the possible prevention by natural polyphenols, Prostate and Testicular carcinogenesis in relation with steroidogenesis and StAR protein expression: role of MAPKs, Molecular signalling of germ cell apoptosis by Benzo(a)pyrene and its protection by natural aryl hydrocarbon receptor (AhR) antagonist as well as Diabetes and Endurance exercise induced systemic & Reproductive disorders and its protection by natural flavonoids and to search the link between Polycystic Ovary Syndrome and both Type 1 and Type 2 Diabetes Mellitus.In the developmental work, Dr. Jana established a State of the Art pre-clinical animal research facility “Centre for Translational Animal Research”, in Bose Institute, Kolkata. Dr. Jana also developed a Non-surgical Chemical Sterilization drug for male animals in the course of his Ph.D. work. Dr. Jana also serving as a CPCSEA, Govt. of India Nominee in several National Research Institutes and Universities to monitor their animal based research works. Based on this research and fellowship training Dr. Jana received several awards and honours, such as: Young Investigator Award, 2011 &International Scientist of the Year, 2011, Young Scientist Award, 2012 & 2014, Outstanding Scientist Award, 2015, Bharat Bikas Award, 2017 and Rastriya Gourav Award, 2018 etc. From USA, Canada, UK & India. He is serving as an Editorial Board Member of several reputed International Journals. He has also authored many international research articles/books. Dr. Janaguided many Ph.D. students and he is also a member of several learned Scientific Societies and visited abroad to deliver invited lectures and Chaired Sessions in many conferences and workshops.

Primary Affiliation: Bose Institute - Calcutta, Bengal , India

Specialties:

Additional Specialties:

Research Interests:


View Dr. Kuladip Jana’s Resume / CV

Publications

37Publications

544Reads

31Profile Views

191PubMed Central Citations

The oxidative dehydrogenation of a coumarinyl scaffold with copper ion and metal ion detection in human liver cancer cells (HepG2).

Dalton Trans 2019 Dec 27;48(48):17818-17830. Epub 2019 Nov 27.

Department of Chemistry, Jadavpur University, Kolkata-700032, India.

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http://dx.doi.org/10.1039/c9dt03870aDOI Listing
December 2019
4.197 Impact Factor

Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives.

Bioorg Med Chem Lett 2019 10 19;29(19):126615. Epub 2019 Aug 19.

Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.08.019DOI Listing
October 2019
2.420 Impact Factor

An Study for Targeted Delivery of Curcumin in Human Triple Negative Breast Carcinoma Cells Using Biocompatible PLGA Microspheres Conjugated with Folic Acid.

J Nanosci Nanotechnol 2019 Jul;19(7):3720-3733

Department of Life Science and Biotechnology, Jadavpur University, Kolkata 700032, India.

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http://dx.doi.org/10.1166/jnn.2019.16292DOI Listing
July 2019
1 Read
1.556 Impact Factor

Aryl quinolinyl hydrazone derivatives as anti-inflammatory agents that inhibit TLR4 activation in the macrophages.

Eur J Pharm Sci 2019 Jun 16;134:102-115. Epub 2019 Apr 16.

Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09280987193015
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http://dx.doi.org/10.1016/j.ejps.2019.04.016DOI Listing
June 2019
20 Reads
3.350 Impact Factor

Aggregation-Induced Emission-Active Hydrazide-Based Probe: Selective Sensing of Al, HF, and Nitro Explosives.

ACS Omega 2019 May 14;4(5):8451-8464. Epub 2019 May 14.

Department of Chemistry and Department of Life Science and Biotechnology, Jadavpur University, Kolkata 700032, India.

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https://pubs.acs.org/doi/10.1021/acsomega.9b00369
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http://dx.doi.org/10.1021/acsomega.9b00369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648475PMC
May 2019
4 Reads

Natural product inspired allicin analogs as novel anti-cancer agents.

Bioorg Chem 2019 05 29;86:259-272. Epub 2019 Jan 29.

Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.01.057DOI Listing
May 2019
2.152 Impact Factor

Protective Effect of Resveratrol on Benzo(a)Pyrene Induced Dysfunctions of Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Leydig Cells.

Front Endocrinol (Lausanne) 2019 30;10:272. Epub 2019 Apr 30.

Division of Molecular Medicine, Bose Institute, Calcutta Improvement Trust Scheme VIIM, Kolkata, India.

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http://dx.doi.org/10.3389/fendo.2019.00272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502972PMC
April 2019
11 Reads

Folic acid conjugated curcumin loaded biopolymeric gum acacia microsphere for triple negative breast cancer therapy in invitro and invivo model.

Mater Sci Eng C Mater Biol Appl 2019 Feb 22;95:204-216. Epub 2018 Oct 22.

Department of Life Science and Biotechnology, Jadavpur University, Kolkata 700032, India. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2018.10.071DOI Listing
February 2019
18 Reads
3.088 Impact Factor

Exploits Macrophage Heme Oxygenase-1 To Neutralize Oxidative Burst and TLR Signaling-Dependent Host Defense.

J Immunol 2019 02 28;202(3):827-840. Epub 2018 Dec 28.

Department of Biochemistry, University of Calcutta, Kolkata 700019, India;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1800958
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http://dx.doi.org/10.4049/jimmunol.1800958DOI Listing
February 2019
33 Reads
4.922 Impact Factor

Hepatoprotective effects of green Capsicum annum against ethanol induced oxidative stress, inflammation and apoptosis in rats.

J Ethnopharmacol 2018 Dec 16;227:69-81. Epub 2018 Aug 16.

Department of Physiology, Rammohan College, 85A, Raja Rammohan Sarani, Kolkata 700009, West Bengal, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03788741173305
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http://dx.doi.org/10.1016/j.jep.2018.08.019DOI Listing
December 2018
10 Reads
3.000 Impact Factor

Multiple paralogues of α-SNAP in Giardia lamblia exhibit independent subcellular localization and redistribution during encystation and stress.

Parasit Vectors 2018 Oct 4;11(1):539. Epub 2018 Oct 4.

Department of Biochemistry, Bose Institute, P 1/12 CIT Road Scheme VII M, Kolkata, West Bengal, 700054, India.

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3112-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172762PMC
October 2018
12 Reads
3.430 Impact Factor

Methylglyoxal at metronomic doses sensitizes breast cancer cells to doxorubicin and cisplatin causing synergistic induction of programmed cell death and inhibition of stemness.

Biochem Pharmacol 2018 10 29;156:322-339. Epub 2018 Aug 29.

Department of Biophysics, Bose Institute, P 1/12 CIT Scheme VII M, Kolkata 700 054, WB, India; Department of Chemistry, Institute of Applied Science & Humanities GLA University Mathura, 17km Stone, NH-2, Mathura-Delhi Road, Mathura 281 406, UP, India. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.08.041DOI Listing
October 2018
1 Read
5.010 Impact Factor

Cari p 1, a Novel Polygalacturonase Allergen From Papaya Acting as Respiratory and Food Sensitizer.

Front Plant Sci 2018 18;9:823. Epub 2018 Jun 18.

Division of Plant Biology, Bose Institute, Kolkata, India.

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http://dx.doi.org/10.3389/fpls.2018.00823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016011PMC
June 2018
3 Reads
3.640 Impact Factor

Antigonadal and endocrine-disrupting activities of lambda cyhalothrin in female rats and its attenuation by taurine.

Toxicol Ind Health 2018 Mar 5;34(3):146-157. Epub 2018 Mar 5.

1 Department of Human Physiology with Community Health, Vidyasagar University, Midnapore, West Bengal, India.

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http://dx.doi.org/10.1177/0748233717742291DOI Listing
March 2018
2 Reads
1.710 Impact Factor

Anticancer drug mithramycin interacts with core histones: An additional mode of action of the DNA groove binder.

FEBS Open Bio 2014 16;4:987-95. Epub 2014 Oct 16.

Biophysics & Structural Genomics Division, Saha Institute of Nuclear Physics, Block-AF, Sector-1, Bidhan Nagar, Kolkata 700064, West Bengal, India.

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http://dx.doi.org/10.1016/j.fob.2014.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247356PMC
December 2014
47 Reads
2 Citations

Alpha-lipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis.

Mol Reprod Dev 2014 Sep 7;81(9):833-50. Epub 2014 Aug 7.

Division of Molecular Medicine, Bose Institute, Calcutta Improvement Trust Scheme VIIM, Kolkata, India.

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http://dx.doi.org/10.1002/mrd.22354DOI Listing
September 2014
27 Reads
5 Citations
2.530 Impact Factor

Synthesis and evaluation of triazole linked glycosylated 18β-glycyrrhetinic acid derivatives as anticancer agents.

Bioorg Med Chem Lett 2014 Aug 27;24(16):3865-8. Epub 2014 Jun 27.

Bose Institute, Division of Molecular Medicine, P 1/12, C.I.T. Scheme VII M, Kolkata 700054, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.06.054DOI Listing
August 2014
10 Reads
4 Citations
2.420 Impact Factor

The DNA intercalators ethidium bromide and propidium iodide also bind to core histones.

FEBS Open Bio 2014 15;4:251-9. Epub 2014 Feb 15.

Biophysics & Structural Genomics Division, Saha Institute of Nuclear Physics, Block-AF, Sector-1, Bidhan Nagar, Kolkata 700064, West Bengal, India.

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http://dx.doi.org/10.1016/j.fob.2014.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958746PMC
March 2014
20 Reads
5 Citations

Recurrent pregnancy loss in polycystic ovary syndrome: role of hyperhomocysteinemia and insulin resistance.

PLoS One 2013 21;8(5):e64446. Epub 2013 May 21.

Department of Infertility, Institute of Reproductive Medicine, Kolkata, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064446PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660299PMC
November 2013
62 Reads
8 Citations
3.234 Impact Factor

Altered trace mineral milieu might play an aetiological role in the pathogenesis of polycystic ovary syndrome.

Biol Trace Elem Res 2013 Apr 16;152(1):9-15. Epub 2013 Jan 16.

Department of Infertility, Institute of Reproductive Medicine, Salt Lake City, Kolkata 700106, India.

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http://dx.doi.org/10.1007/s12011-012-9592-5DOI Listing
April 2013
6 Reads
5 Citations
1.750 Impact Factor

Identification of a novel role of ESAT-6-dependent miR-155 induction during infection of macrophages with Mycobacterium tuberculosis.

Cell Microbiol 2012 Oct 11;14(10):1620-31. Epub 2012 Jul 11.

Department of Chemistry, Bose Institute, Kolkata, India.

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http://dx.doi.org/10.1111/j.1462-5822.2012.01827.xDOI Listing
October 2012
48 Reads
33 Citations
4.920 Impact Factor

Clinical evaluation of non-surgical sterilization of male cats with single intra-testicular injection of calcium chloride.

BMC Vet Res 2011 Jul 21;7:39. Epub 2011 Jul 21.

Division of Molecular Medicine, Bose Institute, Centenary Campus, P 1/12, CIT Scheme, VIIM, Kolkata 700 054, India.

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http://dx.doi.org/10.1186/1746-6148-7-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152893PMC
July 2011
1 Read
5 Citations
1.780 Impact Factor

Ethanol induces mouse spermatogenic cell apoptosis in vivo through over-expression of Fas/Fas-L, p53, and caspase-3 along with cytochrome c translocation and glutathione depletion.

Mol Reprod Dev 2010 Sep;77(9):820-33

Division of Molecular Medicine, Bose Institute, Kolkata, West Bengal, India.

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http://dx.doi.org/10.1002/mrd.21227DOI Listing
September 2010
12 Reads
10 Citations
2.530 Impact Factor

Nicotine diminishes testicular gametogenesis, steroidogenesis, and steroidogenic acute regulatory protein expression in adult albino rats: possible influence on pituitary gonadotropins and alteration of testicular antioxidant status.

Toxicol Sci 2010 Aug 24;116(2):647-59. Epub 2010 May 24.

Department of Surgery and Radiology, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, Kolkata 700037, India.

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http://dx.doi.org/10.1093/toxsci/kfq149DOI Listing
August 2010
7 Reads
17 Citations

Protective effect of sodium selenite and zinc sulfate on intensive swimming-induced testicular gamatogenic and steroidogenic disorders in mature male rats.

Appl Physiol Nutr Metab 2008 Oct;33(5):903-14

Garrison Institute on Aging, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1139/H08-065DOI Listing
October 2008
3 Reads
2.230 Impact Factor

Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.

J Endocrinol 2008 May;197(2):315-23

Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA.

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http://dx.doi.org/10.1677/JOE-07-0282DOI Listing
May 2008
9 Reads
4 Citations
3.720 Impact Factor

Sterilization of male stray dogs with a single intratesticular injection of calcium chloride: a dose-dependent study.

Contraception 2007 May 26;75(5):390-400. Epub 2007 Mar 26.

Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal 700 078, India.

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http://dx.doi.org/10.1016/j.contraception.2007.01.022DOI Listing
May 2007
7 Reads
10 Citations
2.340 Impact Factor

Evaluation of single intratesticular injection of calcium chloride for nonsurgical sterilization in adult albino rats.

Contraception 2006 Mar 20;73(3):289-300. Epub 2005 Oct 20.

Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, Calcutta 700 037, West Bengal, India.

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http://dx.doi.org/10.1016/j.contraception.2005.07.011DOI Listing
March 2006
8 Reads
6 Citations
2.340 Impact Factor

Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action.

Reprod Biol Endocrinol 2006 Feb 16;4. Epub 2006 Feb 16.

Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, 37 and 68, K. B. Sarani, Calcutta-700 037, West Bengal, India.

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http://dx.doi.org/10.1186/1477-7827-4-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1397838PMC
February 2006
9 Reads
24 Citations
2.410 Impact Factor

Evaluation of single intratesticular injection of calcium chloride for nonsurgical sterilization of male Black Bengal goats (Capra hircus): a dose-dependent study.

Anim Reprod Sci 2005 Mar;86(1-2):89-108

Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, 64/1/14 Belgachia Road (Milk Colony), 37 & 68 K.B. Sarani, Calcutta 700037, West Bengal, India.

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http://dx.doi.org/10.1016/j.anireprosci.2004.05.021DOI Listing
March 2005
11 Reads
3 Citations
1.511 Impact Factor

Intensive swimming exercise-induced oxidative stress and reproductive dysfunction in male wistar rats: protective role of alpha-tocopherol succinate.

Can J Appl Physiol 2004 Apr;29(2):172-85

Human Performance Lab, Sports Authority of India, New Delhi, India.

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http://dx.doi.org/10.1139/h04-013DOI Listing
April 2004
8 Reads
7 Citations

Top co-authors

Kunal Pal
Kunal Pal

Jadavpur University

6
Anup Kumar Misra
Anup Kumar Misra

Bose Institute

5
Prabhat Kumar Samanta
Prabhat Kumar Samanta

West Bengal University of Animal and Fishery Sciences

5
Zhumur Ghosh
Zhumur Ghosh

Stanford University School of Medicine

5
Manikuntala Kundu
Manikuntala Kundu

Bose Institute

5
Manish Kumar
Manish Kumar

DAV University

5
Joyoti Basu
Joyoti Basu

Bose Institute

5
Pratip Chakraborty
Pratip Chakraborty

Institute of Reproductive Medicine

4
Indranil Manna
Indranil Manna

Human Performance Lab

3