Krzysztof W Selmaj

Krzysztof W Selmaj

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Krzysztof W Selmaj

Krzysztof W Selmaj

Publications by authors named "Krzysztof W Selmaj"

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Circular RNAs as a novel layer of regulatory mechanism in multiple sclerosis.

J Neuroimmunol 2019 Sep 25;334:576971. Epub 2019 May 25.

Department of Neurology, Laboratory of Neuroimmunology, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2019.576971DOI Listing
September 2019

Multiple sclerosis: Serum-derived exosomes express myelin proteins.

Mult Scler 2018 04 1;24(4):449-458. Epub 2017 Feb 1.

Laboratory of Neuroimmunology, Department of Neurology, Medical University of Lodz, Lodz, Poland.

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http://journals.sagepub.com/doi/10.1177/1352458517696597
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http://dx.doi.org/10.1177/1352458517696597DOI Listing
April 2018

Multiple sclerosis: Skin-induced antigen-specific immune tolerance.

J Neuroimmunol 2017 10 2;311:49-58. Epub 2017 Aug 2.

Department of Neurology, Medical University of Lodz, Lodz, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.08.001DOI Listing
October 2017

Alemtuzumab CARE-MS I 5-year follow-up: Durable efficacy in the absence of continuous MS therapy.

Neurology 2017 Sep 23;89(11):1107-1116. Epub 2017 Aug 23.

From the Department of Neurology and Center for Clinical Neuroscience (E.H.), First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic; NeuroRx Research (D.L.A.), Montréal; Department of Neurology and Neurosurgery (D.L.A.), Montréal Neurological Institute, McGill University, Québec, Canada; Mellen Center (J.A.C.), Cleveland Clinic, OH; Department of Neurology and Center for Neuropsychiatry (H.-P.H.), Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany; MS Clinic of Central Texas (E.J.F.), Central Texas Neurology Consultants, Round Rock; Queen Mary University of London (G.G.), Barts and The London School of Medicine, UK; Neuroimmunology and Multiple Sclerosis Research (S.S.), Department of Neurology, University Hospital Zürich and University of Zürich, Switzerland; Department of Neurology (K.W.S.), Medical University of Łódź, Poland; The University of British Columbia (A.T.), Vancouver, Canada; Department of Clinical Neurosciences (D.A.S.C., A.J.C.), University of Cambridge, UK; Sanofi (D.H.M., K.T., C.E.R., D.J., M.A.P.), Cambridge, MA; Evidence Scientific Solutions (R.J.H.), Sydney, NSW, Australia; and Evidence Scientific Solutions (P.X.), Philadelphia, PA. M.A.P. is currently affiliated with Wave Life Sciences, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000004313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595278PMC
September 2017

Alemtuzumab CARE-MS II 5-year follow-up: Efficacy and safety findings.

Neurology 2017 Sep 23;89(11):1117-1126. Epub 2017 Aug 23.

From the Department of Clinical Neurosciences (A.J.C., D.A.S.C.), University of Cambridge, UK; Mellen Center (J.A.C.), Cleveland Clinic, OH; MS Clinic of Central Texas (E.J.F.), Central Texas Neurology Consultants, Round Rock; Queen Mary University of London (G.G.), Barts and the London School of Medicine, UK; Department of Neurology and Center for Neuropsychiatry (H.-P.H.), Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany; Department of Neurology and Center for Clinical Neuroscience (E.H.), First Faculty of Medicine, Charles University and General Hospital in Prague, Czech Republic; Neuroimmunology and Multiple Sclerosis Research, Department of Neurology (S.S.), University Hospital Zürich and University of Zürich, Switzerland; Department of Neurology (K.W.S.), Medical University of Łódź, Poland; The University of British Columbia (A.T.), Vancouver, Canada; Sanofi (D.H.M., K.T., M.C.C., D.J., M.A.P.), Cambridge, MA; Envision Scientific Solutions (P.X.), Philadelphia, PA; Envision Scientific Solutions (R.J.H.), Sydney, NSW, Australia; NeuroRx Research (D.L.A.), Montréal; Department of Neurology and Neurosurgery (D.L.A.), Montréal Neurological Institute, McGill University, Québec, Canada. M.A.P. is currently affiliated with Wave Life Sciences, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000004354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595276PMC
September 2017

The role of exosomes in CNS inflammation and their involvement in multiple sclerosis.

J Neuroimmunol 2017 05 6;306:1-10. Epub 2017 Feb 6.

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Lodz, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01655728163043
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http://dx.doi.org/10.1016/j.jneuroim.2017.02.002DOI Listing
May 2017

Global exosome transcriptome profiling reveals biomarkers for multiple sclerosis.

Ann Neurol 2017 May;81(5):703-717

Laboratory of Neuroimmunology, Department of Neurology, University of Lodz, Lodz, Poland.

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http://dx.doi.org/10.1002/ana.24931DOI Listing
May 2017

Alemtuzumab improves preexisting disability in active relapsing-remitting MS patients.

Neurology 2016 Nov 12;87(19):1985-1992. Epub 2016 Oct 12.

From Queen Mary University of London (G.G.), Barts and The London School of Medicine, UK; Mellen Center (J.A.C.), Cleveland Clinic, OH; Department of Clinical Neurosciences (A.J.C., D.A.S.C.), University of Cambridge, UK; Department of Neurology and Center for Neuropsychiatry (H.-P.H.), Heinrich-Heine University, Düsseldorf, Germany; Department of Neurology and Center for Clinical Neuroscience (E.H.), First Medical Faculty, Charles University in Prague, Czech Republic; Department of Neurology (K.W.S.), Medical University of Łódź, Poland; Sanofi Genzyme (D.H.M., S.L.L., M.A.P.), Cambridge, MA; and Evidence Scientific Solutions (S.M.K.), Philadelphia, PA (at the time the work was conducted).

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000003319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109953PMC
November 2016

Superior MRI outcomes with alemtuzumab compared with subcutaneous interferon β-1a in MS.

Neurology 2016 Oct 2;87(14):1464-1472. Epub 2016 Sep 2.

From NeuroRx Research (D.L.A.) and Department of Neurology and Neurosurgery (D.L.A.), Montréal Neurological Institute, McGill University, Québec, Canada; Department of Biomedical Engineering (E.F.) and Mellen Center (J.A.C.), Cleveland Clinic, OH; Zagreb Medical School and University Hospital Center (V.V.B.), Croatia; Department of Clinical Neurosciences (A.J.C., D.A.S.C.), University of Cambridge, UK; Queen Mary University of London (G.G.), Barts and the London School of Medicine, UK; Department of Neurology and Center for Neuropsychiatry (H.-P.H.), Heinrich-Heine University, Düsseldorf, Germany; Department of Neurology (E.H.), First Medical Faculty, Charles University in Prague, Czech Republic; Department of Neurology (K.W.S.), Medical University of Łódź, Poland; Clinical Centre Kragujevac (M.S.), Clinic of Neurology, Serbia; Brigham and Women's Hospital Center for Neurologic Diseases (H.L.W.), Boston, MA; Sanofi Genzyme (S.L.L., D.H.M., M.A.P.), Cambridge, MA; and Evidence Scientific Solutions (D.R.T.), Horsham, West Sussex, UK. Dr. Panzara is currently with Wave Life Sciences, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000003169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075976PMC
October 2016

miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40.

J Neurosci 2015 Dec;35(50):16504-15

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, 90-153 Lodz, Poland

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http://dx.doi.org/10.1523/JNEUROSCI.2830-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605508PMC
December 2015

Heat shock protein 70 (Hsp70) interacts with the Notch1 intracellular domain and contributes to the activity of Notch signaling in myelin-reactive CD4 T cells.

J Neuroimmunol 2015 Oct 8;287:19-26. Epub 2015 Aug 8.

Department of Neurology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2015.08.007DOI Listing
October 2015

Plasmocytoid dendritic cell deficit of early response to toll-like receptor 7 agonist stimulation in multiple sclerosis patients.

Clin Immunol 2014 Jul 9;153(1):211-9. Epub 2014 May 9.

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Kopcinskiego 22, 90-153 Lodz, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616140012
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http://dx.doi.org/10.1016/j.clim.2014.04.016DOI Listing
July 2014

Brain glycolipids suppress T helper cells and inhibit autoimmune demyelination.

J Neurosci 2014 Jun;34(25):8646-58

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, 90-153 Lodz, Poland, and

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http://dx.doi.org/10.1523/JNEUROSCI.0885-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608209PMC
June 2014

Transcriptional profiling of microdissected areas of active multiple sclerosis lesions reveals activation of heat shock protein genes.

J Neurosci Res 2012 Oct 20;90(10):1941-8. Epub 2012 Jun 20.

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Lodz, Poland.

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http://dx.doi.org/10.1002/jnr.23079DOI Listing
October 2012

MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination.

Proc Natl Acad Sci U S A 2012 May 18;109(20):E1248-57. Epub 2012 Apr 18.

Laboratory of Neuroimmunology, Department of Neurology, Medical University of Lodz, 90-153, Lodz, Poland.

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http://dx.doi.org/10.1073/pnas.1114325109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356660PMC
May 2012

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Aberrant stress-induced Hsp70 expression in immune cells in multiple sclerosis.

J Neurosci Res 2010 Nov;88(14):3102-10

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Lodz, Poland.

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http://dx.doi.org/10.1002/jnr.22476DOI Listing
November 2010

A heat shock protein gene (Hsp70.1) is critically involved in the generation of the immune response to myelin antigen.

Eur J Immunol 2008 Jul;38(7):1999-2013

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, 22 Kopcinskiego Street, Lodz, Poland.

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http://dx.doi.org/10.1002/eji.200737661DOI Listing
July 2008

Proton magnetic resonance spectroscopy of normal appearing white matter in familial and sporadic multiple sclerosis.

J Neurol 2005 Jul 18;252(7):830-2. Epub 2005 Mar 18.

Dept. of Neurology, Medical University of Lodz, 22, Kopcińskiego Street, 90-153 Lodz, Poland.

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http://dx.doi.org/10.1007/s00415-005-0754-7DOI Listing
July 2005

Gammadelta T cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and IL-12 production.

J Immunol 2004 Jul;173(1):682-94

Department of Neurology, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, Poland.

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http://dx.doi.org/10.4049/jimmunol.173.1.682DOI Listing
July 2004

Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis.

Clin Neurol Neurosurg 2004 Jun;106(3):223-9

Department of Neurology, Medical University of Lodz, 22, Kopcinskiego Street, 90-153 Lodz, Poland.

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http://dx.doi.org/10.1016/j.clineuro.2004.02.019DOI Listing
June 2004

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

J Immunol 2004 Jan;172(1):202-13

Department of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Kopcinskiego Str. 22, 90-153 Lodz, Poland.

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http://dx.doi.org/10.4049/jimmunol.172.1.202DOI Listing
January 2004

A whole genome screen for association in Polish multiple sclerosis patients.

J Neuroimmunol 2003 Oct;143(1-2):107-11

Department of Neurology, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, Poland.

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http://dx.doi.org/10.1016/j.jneuroim.2003.08.022DOI Listing
October 2003

cDNA microarray analysis in multiple sclerosis lesions: detection of genes associated with disease activity.

Brain 2003 May;126(Pt 5):1048-57

Department of Neurology, Medical University of Lodz, Lodz, Poland, Serono Research Institute, Geneva, Switzerland.

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http://dx.doi.org/10.1093/brain/awg107DOI Listing
May 2003

Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains.

Int Immunol 2003 Feb;15(2):241-9

Department of Neurology, Medical University of Lodz, 22, Kopcinskiego Street, 90-153 Lodz, Poland.

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http://dx.doi.org/10.1093/intimm/dxg022DOI Listing
February 2003