Kristy Brown

Kristy Brown

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Kristy Brown

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Tissue Engineering Models for the Study of Breast Neoplastic Disease and the Tumor Microenvironment.

Tissue Eng Part B Rev 2020 Feb 27. Epub 2020 Feb 27.

Weill Cornell Medical College, 12295, New York, New York, United States.

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http://dx.doi.org/10.1089/ten.TEB.2019.0347DOI Listing
February 2020

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.

Cell Rep 2020 Jan;30(3):755-770.e6

Department of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68(th) Street, New York, NY 10065, USA; Meyer Cancer Center, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Department of Cell and Developmental Biology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.12.056DOI Listing
January 2020

AMP-activated protein kinase signaling regulated expression of urea cycle enzymes in response to changes in dietary protein intake.

J Inherit Metab Dis 2019 Nov 1;42(6):1088-1096. Epub 2019 Aug 1.

Center for Genetic Medicine Research, Children's National Medical Center, Washington, District of Columbia.

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http://dx.doi.org/10.1002/jimd.12133DOI Listing
November 2019

Membrane recruitment of nNOSµ in microdystrophin gene transfer to enhance durability.

Neuromuscul Disord 2019 10 23;29(10):735-741. Epub 2019 Aug 23.

Solid Biosciences, 141 Portland Street, Cambridge, MA 02139, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2019.08.009DOI Listing
October 2019

Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression.

J Steroid Biochem Mol Biol 2019 05 6;189:161-170. Epub 2019 Mar 6.

Department of Medicine, Weill Cornell Medicine, New York, USA; Graduate School of Medical Sciences, Weill Cornell Medicine, New York, USA; Department of Physiology, Monash University, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502693PMC
May 2019

Pathological Issues in Dystrophinopathy in the Age of Genetic Therapies.

Annu Rev Pathol 2019 01 27;14:105-126. Epub 2018 Aug 27.

Department of Pathology and Laboratory Medicine, and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA; email: , ,

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http://dx.doi.org/10.1146/annurev-pathmechdis-012418-012945DOI Listing
January 2019

The benefits of adding metformin to tamoxifen to protect the endometrium-A randomized placebo-controlled trial.

Clin Endocrinol (Oxf) 2018 11 9;89(5):605-612. Epub 2018 Sep 9.

Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/cen.13830DOI Listing
November 2018

IL-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue.

FASEB J 2018 06 23;32(6):3361-3370. Epub 2018 Jan 23.

Functional Foods Forum, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1096/fj.201700938RRRDOI Listing
June 2018

Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.

Acta Neuropathol Commun 2018 06 7;6(1):48. Epub 2018 Jun 7.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Health System, Washington, DC, USA.

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http://dx.doi.org/10.1186/s40478-018-0548-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992829PMC
June 2018

Obesity and breast cancer - Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue.

Mol Cell Endocrinol 2018 05 15;466:15-30. Epub 2017 Sep 15.

Metabolism & Cancer Laboratory, Hudson Institute of Medical Research, Clayton, VIC, Australia; Department of Physiology, Monash University, Clayton, VIC, Australia; Department of Medicine, Weill Cornell Medicine, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.09.014DOI Listing
May 2018

Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.

FASEB J 2018 04 5;32(4):1855-1867. Epub 2018 Jan 5.

Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, Washington, DC, USA.

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http://dx.doi.org/10.1096/fj.201700248RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893168PMC
April 2018

Abnormal neurofilament inclusions and segregations in dorsal root ganglia of a Charcot-Marie-Tooth type 2E mouse model.

PLoS One 2017 27;12(6):e0180038. Epub 2017 Jun 27.

Department of Pathology and Cell Biology and Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians & Surgeons, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180038PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487060PMC
September 2017

Des-acyl ghrelin inhibits the capacity of macrophages to stimulate the expression of aromatase in breast adipose stromal cells.

J Steroid Biochem Mol Biol 2017 06 14;170:49-53. Epub 2016 Jul 14.

Metabolism and Cancer Laboratory, Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia; Department of Physiology, Monash University, Clayton, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2016.07.005DOI Listing
June 2017

Purification and characterization of microRNAs within middle ear fluid exosomes: implication in otitis media pathophysiology.

Pediatr Res 2017 Jun 3;81(6):911-918. Epub 2017 Feb 3.

Sheikh Zayed Center for Pediatric Surgical Innovation, Children's National Health System, Washington, DC.

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http://dx.doi.org/10.1038/pr.2017.25DOI Listing
June 2017

Editorial.

J Steroid Biochem Mol Biol 2017 06;170

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http://dx.doi.org/10.1016/j.jsbmb.2017.04.014DOI Listing
June 2017

Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy.

Cell Death Differ 2017 02 11;24(2):330-342. Epub 2016 Nov 11.

Center for Genetic Medicine Research, Children's National Health System, 111 Michigan Avenue NW, Washington, DC 20010, USA.

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http://dx.doi.org/10.1038/cdd.2016.127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299714PMC
February 2017

The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer.

Breast Cancer Res Treat 2017 01 15;161(2):213-227. Epub 2016 Nov 15.

Department of Anatomical Pathology and Surgery, Tohoku University School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.

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http://dx.doi.org/10.1007/s10549-016-4050-2DOI Listing
January 2017

Ghrelin and Breast Cancer: Emerging Roles in Obesity, Estrogen Regulation, and Cancer.

Front Oncol 2016 9;6:265. Epub 2017 Jan 9.

Metabolism and Cancer Laboratory, Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia; Department of Molecular and Translational Sciences, Monash University, Clayton, VIC, Australia; Department of Physiology, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fonc.2016.00265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220482PMC
January 2017

Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer.

Curr Opin Pharmacol 2016 12 19;31:90-96. Epub 2016 Nov 19.

Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Monash University, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2016.11.003DOI Listing
December 2016

The use of proteomic analysis to study trafficking defects in axons.

Methods Cell Biol 2016 2;131:151-62. Epub 2015 Sep 2.

Center for Neuroscience Research, Children's National Health System, Washington, DC, USA.

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http://dx.doi.org/10.1016/bs.mcb.2015.06.009DOI Listing
October 2016

Somatic mosaicism due to a reversion variant causing hemi-atrophy: a novel variant of dystrophinopathy.

Eur J Hum Genet 2016 10 9;24(10):1511-4. Epub 2016 Mar 9.

Department of Integrative Systems Biology, The George Washington University School of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1038/ejhg.2016.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027673PMC
October 2016

PARP1 Differentially Interacts with Promoter region of Gene in FSHD Myoblasts.

J Genet Syndr Gene Ther 2016 Aug 8;7(4). Epub 2016 Aug 8.

Center for Genetic Medicine Research, Children's National Health System, Washington DC, USA; Department of Integrative Systems Biology, George Washington University, Washington DC, USA.

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https://www.omicsonline.org/open-access/parp1-differentially
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051271PMC
http://dx.doi.org/10.4172/2157-7412.1000303DOI Listing
August 2016

SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi.

PLoS One 2016 9;11(2):e0148612. Epub 2016 Feb 9.

Sheikh Zayed Center for Pediatric Surgical Innovation, Children's National Health System, Washington, DC, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148612PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747582PMC
July 2016

Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.

J Biol Chem 2016 07 1;291(31):16011-23. Epub 2016 Jun 1.

From the Department of Medicine, Weill Cornell Medical College, New York, New York 10065.

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http://dx.doi.org/10.1074/jbc.M115.698902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965552PMC
July 2016

Clinical utility of serum biomarkers in Duchenne muscular dystrophy.

Clin Proteomics 2016 5;13. Epub 2016 Apr 5.

Center for Genetic Medicine, Children's National Healthy System, Washington, DC USA.

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http://dx.doi.org/10.1186/s12014-016-9109-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820909PMC
April 2016

A proteomic characterization of NTHi lysates.

Int J Pediatr Otorhinolaryngol 2016 Jan 24;80:8-16. Epub 2015 Nov 24.

Sheihk Zayed Institute, Washington, DC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijporl.2015.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706994PMC
January 2016

Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes.

Nat Commun 2016 Jan 19;7:10312. Epub 2016 Jan 19.

Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1038/ncomms10312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735644PMC
January 2016

p53: Protection against Tumor Growth beyond Effects on Cell Cycle and Apoptosis.

Cancer Res 2015 Dec 16;75(23):5001-7. Epub 2015 Nov 16.

Metabolism and Cancer Laboratory, Centres for Cancer Research and Endocrinology and Metabolism, Hudson Institute of Medical Research, Clayton, Victoria, Australia. Department of Physiology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0563DOI Listing
December 2015

Aicardi-Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies.

Ann Rheum Dis 2015 Oct 6;74(10):1931-9. Epub 2014 Jun 6.

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam (UvA), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2014-205396DOI Listing
October 2015

Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer.

J Steroid Biochem Mol Biol 2015 Sep 21;153:35-44. Epub 2015 Jul 21.

Metabolism & Cancer Laboratory, Centre for Cancer Research, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia; Department of Physiology, Monash University, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2015.07.008DOI Listing
September 2015

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy.

Cell Rep 2015 Sep 28;12(10):1678-90. Epub 2015 Aug 28.

Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC 20010, USA; Department of Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.07.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757433PMC
September 2015

Obesity-Associated Inflammatory Cytokines and Prostaglandin E2 Stimulate Glucose Transporter mRNA Expression and Glucose Uptake in Primary Human Adipose Stromal Cells.

J Interferon Cytokine Res 2015 Aug 3;35(8):600-5. Epub 2015 Apr 3.

1 Metabolism & Cancer Laboratory, Centre for Cancer Research, MIMR-PHI Institute of Medical Research , Victoria, Australia .

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http://dx.doi.org/10.1089/jir.2014.0194DOI Listing
August 2015

Secretome survey of human plexiform neurofibroma derived Schwann Cells reveals a secreted form of the RARRES1 protein.

Int J Mol Sci 2012 24;13(7):9380-99. Epub 2012 Jul 24.

Children's National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA; E-Mails: (H.-L.C.); (H.S.); (K.J.B.); (H.G.-D.); (A.H.); (V.G.); (R.P.).

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http://dx.doi.org/10.3390/ijms13079380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430302PMC
July 2015

Estrogens, obesity, inflammation, and breast cancer-what is the link?

Semin Reprod Med 2015 May 2;33(3):208-12. Epub 2015 Jun 2.

MIMR-PHI Centre for Medical Research, Monash Medical Centre, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1055/s-0035-1552581DOI Listing
May 2015

Neurofilament light polypeptide gene N98S mutation in mice leads to neurofilament network abnormalities and a Charcot-Marie-Tooth Type 2E phenotype.

Hum Mol Genet 2015 Apr 30;24(8):2163-74. Epub 2014 Dec 30.

Department of Pathology and Cell Biology, Taub Institute for Research in Alzheimer's Disease and the Aging Brain and

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http://dx.doi.org/10.1093/hmg/ddu736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380066PMC
April 2015

Proteomic analysis of pediatric sinonasal secretions shows increased MUC5B mucin in CRS.

Pediatr Res 2015 Feb 24;77(2):356-62. Epub 2014 Nov 24.

1] Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC [2] Department of Integrative Systems Biology, Children's National Medical Center, Washington, DC [3] Division of Pediatric Otolaryngology-Head and Neck Surgery, Children's National Medical Center, Washington, DC.

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http://dx.doi.org/10.1038/pr.2014.187DOI Listing
February 2015

Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.

J Biol Chem 2015 Feb 7;290(9):5267-79. Epub 2015 Jan 7.

the Department of Pathology and Cell Biology, Taub Center for Alzheimer's Disease, College of Physicians and Surgeons, Columbia University, New York, New York 10032.

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http://dx.doi.org/10.1074/jbc.M114.575225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342447PMC
February 2015

Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer.

Cancer Res 2015 Feb 29;75(4):645-55. Epub 2015 Jan 29.

Metabolism and Cancer Laboratory, Centre for Cancer Research, MIMR-PHI Institute of Medical Research, Clayton, Victoria, Australia. Department of Physiology, Monash University, Clayton, Victoria, Australia.

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http://cancerres.aacrjournals.org/content/75/4/645.full.pdf
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-14-2164DOI Listing
February 2015

The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse.

Toxicol Rep 2015;2:838-849

The Centers for Genetic Medicine Research and Translational Science, Children's Research Institute, Children's National Medical Center, 111 Michigan Avenue, NW, Washington, DC 20010, USA.

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http://dx.doi.org/10.1016/j.toxrep.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512206PMC
January 2015

Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repair.

Nat Commun 2014 Dec 23;5:5646. Epub 2014 Dec 23.

1] Children's National Medical Center, Center for Genetic Medicine Research, 111 Michigan Avenue, NW, Washington DC 20010-2970, USA [2] Department of Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington DC, USA.

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http://www.nature.com/articles/ncomms6646
Publisher Site
http://dx.doi.org/10.1038/ncomms6646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333728PMC
December 2014

Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism.

Breast Cancer Res Treat 2014 Aug 24;147(1):193-201. Epub 2014 Jul 24.

Metabolism & Cancer Laboratory, MIMR-PHI Institute of Medical Research, Clayton, VIC, 3168, Australia.

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http://dx.doi.org/10.1007/s10549-014-3060-1DOI Listing
August 2014

Impact of obesity on mammary gland inflammation and local estrogen production.

Authors:
Kristy A Brown

J Mammary Gland Biol Neoplasia 2014 Jul 17;19(2):183-9. Epub 2014 Jun 17.

Metabolism & Cancer Laboratory, MIMR-PHI Institute of Medical Research, Clayton, VIC, Australia,

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http://dx.doi.org/10.1007/s10911-014-9321-0DOI Listing
July 2014

Conditional overexpression of liver receptor homolog-1 in female mouse mammary epithelium results in altered mammary morphogenesis via the induction of TGF-β.

Endocrinology 2014 May 24;155(5):1606-17. Epub 2014 Feb 24.

Cancer Drug Discovery Laboratory (K.A.L., M.J.Y., Z.Z., R.S.C., A.L.C., C.D.C.) and Metabolism and Cancer Laboratory (K.A.B.), Prince Henry's Institute of Medical Research, Clayton, Victoria 3168, Australia; Environmental and Biotechnology Centre (K.A.L.), Swinburne University, Hawthorn, Victoria 3122, Australia; and Department of Biochemistry and Molecular Biology (C.D.C.), Monash University, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1210/en.2013-1948DOI Listing
May 2014

Genomic basis of aromatase excess syndrome: recombination- and replication-mediated rearrangements leading to CYP19A1 overexpression.

J Clin Endocrinol Metab 2013 Dec 24;98(12):E2013-21. Epub 2013 Sep 24.

MD, Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2-10-1 Ohkura, Setagaya, Tokyo 157-8535, Japan.

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http://dx.doi.org/10.1210/jc.2013-2520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399493PMC
December 2013

Obesity and breast cancer: role of inflammation and aromatase.

J Mol Endocrinol 2013 Dec 26;51(3):T51-9. Epub 2013 Nov 26.

Metabolism and Cancer Laboratory, Prince Henry's Institute of Medical Research, Clayton, Victoria 3168, Australia Departments ofBiochemistry and Molecular Biology Physiology, Monash University, Clayton, Victoria 3168, Australia.

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https://jme.bioscientifica.com/view/journals/jme/51/3/T51.xm
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http://dx.doi.org/10.1530/JME-13-0217DOI Listing
December 2013

The human secretome atlas initiative: implications in health and disease conditions.

Biochim Biophys Acta 2013 Nov 19;1834(11):2454-61. Epub 2013 Apr 19.

Center for Genetic Medicine Research, Children's National Medical Center, Washington DC 20010, USA.

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http://dx.doi.org/10.1016/j.bbapap.2013.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755092PMC
November 2013

Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogs.

Am J Pathol 2013 Nov;183(5):1411-24

Department of Integrative Systems Biology, George Washington University School of Medicine, Washington, District of Columbia; Research Center for Genetic Medicine, Children's National Medical Center, Washington, District of Columbia.

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http://dx.doi.org/10.1016/j.ajpath.2013.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814684PMC
November 2013

Interlaboratory study on differential analysis of protein glycosylation by mass spectrometry: the ABRF glycoprotein research multi-institutional study 2012.

Mol Cell Proteomics 2013 Oct 13;12(10):2935-51. Epub 2013 Jun 13.

Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts 02118;

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http://dx.doi.org/10.1074/mcp.M113.030643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790302PMC
October 2013

Propranolol-mediated attenuation of MMP-9 excretion in infants with hemangiomas.

JAMA Otolaryngol Head Neck Surg 2013 Oct;139(10):1026-31

Sheik Zayed Center for Pediatric Surgical Innovation, Children's National Medical Center, Washington, DC.

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http://dx.doi.org/10.1001/jamaoto.2013.4773DOI Listing
October 2013

CREB-regulated transcription co-activator family stimulates promoter II-driven aromatase expression in preadipocytes.

Horm Cancer 2013 Aug 13;4(4):233-41. Epub 2013 Apr 13.

Metabolism and Cancer Laboratory, Prince Henry's Institute, Block E level 4, 246 Clayton Rd, Clayton, P.O. Box 5152, Melbourne, VIC, 3168, Australia.

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http://dx.doi.org/10.1007/s12672-013-0142-1DOI Listing
August 2013

Dystrophin deficiency leads to disturbance of LAMP1-vesicle-associated protein secretion.

Cell Mol Life Sci 2013 Jun 24;70(12):2159-74. Epub 2013 Jan 24.

Center for Genetic Medicine, Children's Research Institute, Children's National Medical Center, 111 Michigan Avenue, Washington, DC, USA.

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http://dx.doi.org/10.1007/s00018-012-1248-2DOI Listing
June 2013

Minireview: Obesity and breast cancer: a tale of inflammation and dysregulated metabolism.

Mol Endocrinol 2013 May 21;27(5):715-25. Epub 2013 Mar 21.

Prince Henry's Institute of Medical Research-Monash Medical Centre, Block E, Level 4246 Clayton Road, PO Box 5152, Clayton, Victoria-3168, Australia.

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http://dx.doi.org/10.1210/me.2013-1011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416759PMC
May 2013

Endocrine-related cancers and the role of AMPK.

Mol Cell Endocrinol 2013 Feb 16;366(2):170-9. Epub 2012 Jul 16.

Metabolism and Cancer Laboratory, Prince Henry's Institute, Clayton 3168, Australia.

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http://dx.doi.org/10.1016/j.mce.2012.06.016DOI Listing
February 2013

Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons.

J Neurosci 2013 Jan;33(2):709-21

Center for Neuroscience Research and Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4603-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711551PMC
January 2013

The involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells.

J Biol Chem 2012 Dec 23;287(51):42469-79. Epub 2012 Oct 23.

Department of Biochemistry and Molecular Biology, The George Washington University Medical School, Washington, D. C. 20037, USA.

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http://dx.doi.org/10.1074/jbc.M112.404277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522249PMC
December 2012

Accurate Quantitation of Dystrophin Protein in Human Skeletal Muscle Using Mass Spectrometry.

J Bioanal Biomed 2012 Dec;Suppl 7

Children's National Medical Center, Center for Genetic Medicine Research, USA ; Department of Integrative Systems Biology, The George Washington University, 2300 Eye Street, N.W., Ross 605, Washington, D.C. USA.

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http://dx.doi.org/10.4172/1948-593X.S7-001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642779PMC
December 2012

Use of quantitative membrane proteomics identifies a novel role of mitochondria in healing injured muscles.

J Biol Chem 2012 Aug 9;287(36):30455-67. Epub 2012 Jul 9.

Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1074/jbc.M112.354415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436295PMC
August 2012

Obesity and breast cancer: mechanisms and therapeutic implications.

Front Biosci (Elite Ed) 2012 Jun 1;4:2515-24. Epub 2012 Jun 1.

Metabolism and Cancer Laboratory, Prince Henry's Institute, Clayton, Australia, 3168.

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http://dx.doi.org/10.2741/e562DOI Listing
June 2012

Advances in the proteomic investigation of the cell secretome.

Expert Rev Proteomics 2012 Jun;9(3):337-45

Children's National Medical Center, Center for Genetic Medicine Research, 111 Michigan Avenue NW, Washington, DC 20010, USA.

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http://dx.doi.org/10.1586/epr.12.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500636PMC
June 2012

Applying health information technology and team-based care to residency education.

Fam Med 2011 Nov-Dec;43(10):726-30

Department of Family Medicine, University of Michigan, USA.

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March 2012

A novel melano-lysosome in the retinal epithelium of rhesus monkeys.

Exp Eye Res 2011 Dec 2;93(6):937-46. Epub 2011 Nov 2.

Department of Ophthalmology, Columbia University, 630 W 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.exer.2011.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314486PMC
December 2011

LKB1 expression is inhibited by estradiol-17β in MCF-7 cells.

J Steroid Biochem Mol Biol 2011 Nov 12;127(3-5):439-43. Epub 2011 Jun 12.

Prince Henry's Institute, Block E Level 4, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne, Victoria 3168, Australia.

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http://dx.doi.org/10.1016/j.jsbmb.2011.06.005DOI Listing
November 2011

Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells.

Fertil Steril 2011 Nov 13;96(5):1246-51.e1. Epub 2011 Sep 13.

Biomedical Sciences, St George's, University of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.fertnstert.2011.08.015DOI Listing
November 2011

Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection.

Mol Cell Proteomics 2011 Oct 8;10(10):M111.009936. Epub 2011 Jul 8.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center, 111 Michigan Avenue, NW, Washington, DC 20010, USA.

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http://www.mcponline.org/cgi/doi/10.1074/mcp.M111.009936
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205871PMC
October 2011

Promoter-specific effects of metformin on aromatase transcript expression.

Steroids 2011 Jul 15;76(8):768-71. Epub 2011 Mar 15.

Prince Henry's Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1016/j.steroids.2011.02.041DOI Listing
July 2011

Teasing out the role of aromatase in the healthy and diseased testis.

Spermatogenesis 2011 Jul 1;1(3):240-249. Epub 2011 Jul 1.

Prince Henry's Institute of Medical Research; Clayton, VIC Australia.

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http://dx.doi.org/10.4161/spmg.1.3.18037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271666PMC
July 2011

Obesity, aromatase and breast cancer.

Expert Rev Endocrinol Metab 2011 May;6(3):383-395

a Prince Henry's Institute of Medical Research, and the Departments of Biochemistry and Physiology, Monash University, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1586/eem.11.35DOI Listing
May 2011

Integrated genomics and proteomics of the Torpedo californica electric organ: concordance with the mammalian neuromuscular junction.

Skelet Muscle 2011 May 4;1(1):20. Epub 2011 May 4.

Department of Biochemistry and Molecular Genetics, IBS, George Washington University, Washington DC, USA.

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http://dx.doi.org/10.1186/2044-5040-1-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156643PMC
May 2011

Evolution and comparative genomics of subcellular specializations: EST sequencing of Torpedo electric organ.

Mar Genomics 2011 Mar 12;4(1):33-40. Epub 2011 Feb 12.

Research Center for Genetic Medicine, Children's National Medical Center, Department of Integrative Systems Biology, The George Washington University School of Medicine & Health Sciences, Washington, DC 20010, United States.

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http://dx.doi.org/10.1016/j.margen.2010.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412124PMC
March 2011

Time series proteome profiling.

Methods Mol Biol 2011 ;694:365-77

Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1007/978-1-60761-977-2_22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151876PMC
February 2011

Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase.

Breast Cancer Res Treat 2010 Sep 19;123(2):591-6. Epub 2010 Mar 19.

Prince Henry's Institute of Medical Research, P.O. Box 5152, Clayton, VIC, 3168, Australia.

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http://link.springer.com/10.1007/s10549-010-0834-y
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September 2010

MUC5B Is the predominant mucin glycoprotein in chronic otitis media fluid.

Pediatr Res 2010 Sep;68(3):231-6

Department of Pediatric Otolaryngology-Head and Neck Surgery, Center for Genetic Medicine Research, Children's National Medical Center, 111 Michigan Avenue Northwest, Washington, DC 20001, USA.

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http://dx.doi.org/10.1203/PDR.0b013e3181eb2eccDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679171PMC
September 2010