Publications by authors named "Kristina Althoff"

21Publications

Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.

Angew Chem Int Ed Engl 2019 12 8;58(52):18823-18829. Epub 2019 Nov 8.

Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.

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December 2019

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.

Cancer Lett 2019 03 4;445:24-33. Epub 2019 Jan 4.

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Germany; German Consortium for Translational Cancer Research (DKTK), Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany. Electronic address:

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March 2019

MYCN-mediated murine cancer models.

Aging (Albany NY) 2017 Apr;9(4):1084-1085

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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April 2017

Towards diagnostic application of non-coding RNAs in neuroblastoma.

Expert Rev Mol Diagn 2016 12 15;16(12):1307-1313. Epub 2016 Nov 15.

a Department of Pediatric Oncology and Hematology , University Children's Hospital Essen , Essen , Germany.

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December 2016

Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines.

Clin Exp Ophthalmol 2017 Apr 10;45(3):288-296. Epub 2016 Nov 10.

Department of Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany.

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April 2017

Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition.

Clin Cancer Res 2016 05 2;22(10):2470-81. Epub 2015 Dec 2.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany. German Consortium for Translational Cancer Research (DKTK), Partner Site Essen/Duesseldorf, Essen, Germany. Neuroblastoma Genomics, B087, German Cancer Research Center (DKFZ), Heidelberg, Germany. Translational Neuro-Oncology, West German Cancer Center (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany. Centre for Medical Biotechnology, University Duisburg-Essen, Essen, Germany.

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May 2016