Publications by authors named "Krishna Das Saha"

52Publications

Chrysin-loaded PLGA attenuates OVA-induced allergic asthma by modulating TLR/NF-κB/NLRP3 axis.

Nanomedicine 2020 11 25;30:102292. Epub 2020 Aug 25.

Cancer Biology & Inflammatory Disorder, Indian Institute of Chemical Biology (CSIR-IICB), Kolkata, West Bengal, India. Electronic address:

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November 2020

A Novel Cyclic Mobile Transporter Can Induce Apoptosis by Facilitating Chloride Anion Transport into Cells.

ACS Omega 2020 Jul 2;5(27):16395-16405. Epub 2020 Jul 2.

Structural Biology and Bioinformatics Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.

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July 2020

Pro-Oxidant Therapeutic Activities of Cerium Oxide Nanoparticles in Colorectal Carcinoma Cells.

ACS Omega 2020 May 26;5(17):9714-9723. Epub 2020 Apr 26.

CSIR-Central Glass and Ceramic Research Institute, 196 Raja S.C. Mullick Road, Kolkata 700032, West Bengal, India.

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May 2020

Designing of novel zinc(ii) Schiff base complexes having acyl hydrazone linkage: study of phosphatase and anti-cancer activities.

Dalton Trans 2020 Jan 6;49(4):1232-1240. Epub 2020 Jan 6.

Department of Chemistry, University of Calcutta, 92 A. P. C. Road, Kolkata 700009, India.

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January 2020

Tannic acid and vitamin E loaded PLGA nanoparticles ameliorate hepatic injury in a chronic alcoholic liver damage model via EGFR-AKT-STAT3 pathway.

Nanomedicine (Lond) 2020 02 2;15(3):235-257. Epub 2019 Dec 2.

Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, West Bengal, Kolkata-700032, India.

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February 2020

Ferulic acid enhances the radiation sensitivity of lung and liver carcinoma cells by collapsing redox homeostasis: mechanistic involvement of Akt/p38 MAPK signalling pathway.

Free Radic Res 2019 Oct 2;53(9-10):944-967. Epub 2019 Oct 2.

Department of Physiology, Center for Nanoscience and Nanotechnology, and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta , Kolkata , India.

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October 2019

Intracellular anti-leishmanial effect of Spergulin-A, a triterpenoid saponin of .

Infect Drug Resist 2019 17;12:2933-2942. Epub 2019 Sep 17.

Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.

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September 2019

Inhibition of TGF-β induced lipid droplets switches M2 macrophages to M1 phenotype.

Toxicol In Vitro 2019 Aug 28;58:207-214. Epub 2019 Mar 28.

Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, India. Electronic address:

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August 2019

Amelioration of diabetic nephropathy using pomegranate peel extract-stabilized gold nanoparticles: assessment of NF-κB and Nrf2 signaling system.

Int J Nanomedicine 2019 7;14:1753-1777. Epub 2019 Mar 7.

Cancer Biology and Inflammatory Disorder Division, Council of Scientific & Industrial Research-Indian Institute of Chemical Biology, Kolkata 700032, West Bengal, India,

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April 2019

Efficient Detection of Early Events of α-Synuclein Aggregation Using a Cysteine Specific Hybrid Scaffold.

Biochemistry 2019 02 6;58(8):1109-1119. Epub 2019 Feb 6.

Structural Biology and Bioinformatics Division , Indian Institute of Chemical Biology (CSIR-IICB) , 4 Raja S. C. Mullick Road , Kolkata 700032 , India.

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February 2019

Synthesis of Triazole-Substituted Quinazoline Hybrids for Anticancer Activity and a Lead Compound as the EGFR Blocker and ROS Inducer Agent.

ACS Omega 2018 Nov 28;3(11):16134-16142. Epub 2018 Nov 28.

Organic & Medicinal Chemistry Division, Academy of Scientific and Innovative Research (AcSIR), and Cancer Biology & Inflammatory Disorder, Indian Institute of Chemical Biology (CSIR-IICB), 4 Raja S. C. Mullick Road, Kolkata 700032, India.

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November 2018

Bromelain with peroxidase from pineapple are more potent to target leukemia growth inhibition - A comparison with only bromelain.

Toxicol In Vitro 2019 Mar 17;55:24-32. Epub 2018 Nov 17.

Immunology Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar, 799102 Agartala, Tripura, India. Electronic address:

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March 2019

Correction: A new triazine based π-conjugated mesoporous 2D covalent organic framework: its in vitro anticancer activities.

Chem Commun (Camb) 2018 11 16;54(86):12270. Epub 2018 Oct 16.

Department of Materials Science, Indian Association for the Cultivation of Science Jadavpur, Kolkata - 700 032, India.

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November 2018

A new triazine based π-conjugated mesoporous 2D covalent organic framework: its in vitro anticancer activities.

Chem Commun (Camb) 2018 Oct;54(81):11475-11478

Department of Materials Science, Indian Association for the Cultivation of Science Jadavpur, Kolkata - 700 032, India.

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October 2018

Porous Polymer Bearing Polyphenolic Organic Building Units as a Chemotherapeutic Agent for Cancer Treatment.

ACS Omega 2018 Jan 17;3(1):529-535. Epub 2018 Jan 17.

Department of Materials Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India.

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January 2018

Covalent Organic Framework Material Bearing Phloroglucinol Building Units as a Potent Anticancer Agent.

ACS Appl Mater Interfaces 2017 Sep 5;9(37):31411-31423. Epub 2017 Sep 5.

Department of Materials Science, Indian Association for the Cultivation of Science , Jadavpur, Kolkata 700 032, India.

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September 2017

A novel nanohybrid for cancer theranostics: folate sensitized FeO nanoparticles for colorectal cancer diagnosis and photodynamic therapy.

J Mater Chem B 2017 Jun 11;5(21):3927-3939. Epub 2017 May 11.

Department of Chemical, Biological and Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Block JD, Sector III, Salt Lake, Kolkata 700106, India.

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June 2017

Synthesis of a novel glucose capped gold nanoparticle as a better theranostic candidate.

PLoS One 2017 5;12(6):e0178202. Epub 2017 Jun 5.

Department of Studies in Physics, Mangalore University, Mangalagangotri, Karnataka, India.

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September 2017

Attenuated Leishmania induce pro-inflammatory mediators and influence leishmanicidal activity by p38 MAPK dependent phagosome maturation in Leishmania donovani co-infected macrophages.

Sci Rep 2016 Mar 1;6:22335. Epub 2016 Mar 1.

Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata-700032, India.

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March 2016

Enhanced protective activity of nano formulated andrographolide against arsenic induced liver damage.

Chem Biol Interact 2015 Dec 17;242:281-9. Epub 2015 Oct 17.

Cancer Biology and Inflammatory Disorder, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata 700032, West Bengal, India. Electronic address:

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December 2015

Structural findings of phenylindoles as cytotoxic antimitotic agents in human breast cancer cell lines through multiple validated QSAR studies.

Toxicol In Vitro 2015 Oct 27;29(7):1392-404. Epub 2015 May 27.

Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P.O. Box 17020, Jadavpur University, Kolkata 700032, India. Electronic address:

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October 2015

Antineoplastic impact of leishmanial sphingolipid in tumour growth with regulation of angiogenic event and inflammatory response.

Apoptosis 2015 Jun;20(6):869-82

Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, 700032, West Bengal, India.

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June 2015

Lipid from infective L. donovani regulates acute myeloid cell growth via mitochondria dependent MAPK pathway.

PLoS One 2015 9;10(3):e0120509. Epub 2015 Mar 9.

Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata-700032, West Bengal, India.

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January 2016

Comparative validated molecular modeling of p53-HDM2 inhibitors as antiproliferative agents.

Eur J Med Chem 2015 Jan 8;90:860-75. Epub 2014 Dec 8.

Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P.O. Box 17020, Jadavpur University, Kolkata 700032, India. Electronic address:

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January 2015

Leishmanial sphingolipid induces apoptosis in Sarcoma 180 cancer cells through regulation of tumour growth via angiogenic switchover.

Tumour Biol 2015 Apr 19;36(4):3109-18. Epub 2014 Dec 19.

Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, West Bengal, 700032, India.

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April 2015

Porous polyurea network showing aggregation induced white light emission, applications as biosensor and scaffold for drug delivery.

ACS Appl Mater Interfaces 2014 Dec 10;6(24):22569-76. Epub 2014 Dec 10.

Department of Material Science, Institution Association for the Cultivation of Science , Jadavpur, Kolkata 700032, India.

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December 2014

Leishmanial lipid affords protection against oxidative stress induced hepatic injury by regulating inflammatory mediators and confining apoptosis progress.

Toxicol Lett 2015 Jan 23;232(2):499-512. Epub 2014 Nov 23.

Cancer Biology & Inflammatory Disorder Division, CSIR - Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, West Bengal 700032, India. Electronic address:

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January 2015

Stepwise development of structure-activity relationship of diverse PARP-1 inhibitors through comparative and validated in silico modeling techniques and molecular dynamics simulation.

J Biomol Struct Dyn 2015 28;33(8):1756-79. Epub 2014 Oct 28.

a Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology , Jadavpur University , P.O. Box 17020, Kolkata 700032 , India.

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February 2016

Lipid isolated from a Leishmania donovani strain reduces Escherichia coli induced sepsis in mice through inhibition of inflammatory responses.

Mediators Inflamm 2014 9;2014:409694. Epub 2014 Jul 9.

Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, West Bengal 700032, India.

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April 2015

Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model.

PLoS One 2014 22;9(5):e97599. Epub 2014 May 22.

Department of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India.

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June 2015

Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis.

J Leukoc Biol 2014 Aug 2;96(2):325-36. Epub 2014 Apr 2.

Cancer Biology and Inflammatory Disorder Division, Council of Scientific and Industrial Research-Indian Institute of Chemical Biology, West Bengal, India; and

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August 2014

Gold (I) N-heterocyclic carbene complex inhibits mouse melanoma growth by p53 upregulation.

Mol Cancer 2014 Mar 13;13:57. Epub 2014 Mar 13.

Cancer Biology and Inflammatory Disorder division, CSIR-Indian Institute of Chemical Biology, Kolkata, West Bengal 700032, India.

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March 2014

Anthracene-bisphosphonate based novel fluorescent organic nanoparticles explored as apoptosis inducers of cancer cells.

Chem Commun (Camb) 2013 Oct;49(82):9461-3

Department of Materials Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.

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October 2013

Exploring the anti-inflammatory activity of a novel 2-phenylquinazoline analog with protection against inflammatory injury.

Toxicol Appl Pharmacol 2012 Oct 7;264(2):182-91. Epub 2012 Aug 7.

Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata-700032, West Bengal, India.

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October 2012

Anticancer potential of 3-(arylideneamino)-2-phenylquinazoline-4(3H)-one derivatives.

Cell Physiol Biochem 2012 1;29(1-2):251-60. Epub 2012 Mar 1.

Cancer & Cell Biology Division, CSIR, Indian Institute of Chemical Biology, Kolkata, West Bengal, India.

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July 2012

Nanocapsulated curcumin: oral chemopreventive formulation against diethylnitrosamine induced hepatocellular carcinoma in rat.

Chem Biol Interact 2012 Feb 16;195(3):206-14. Epub 2011 Dec 16.

Drug Development/Diagnostics & Biotechnology Department, Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700032, India.

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February 2012

Quercetin in vesicular delivery systems: evaluation in combating arsenic-induced acute liver toxicity associated gene expression in rat model.

Chem Biol Interact 2010 Jun 4;186(1):61-71. Epub 2010 Apr 4.

Biomembrane Division, Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, India.

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June 2010

Attenuated Leishmanial sphingolipid induces apoptosis in A375 human melanoma cell via both caspase-dependent and -independent pathways.

Mol Cell Biochem 2007 Oct 25;304(1-2):143-54. Epub 2007 May 25.

Cellular Biochemistry Division, Indian Institute of Chemical Biology, Jadavpur, Kolkata 700032, India.

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October 2007

A sphingolipid rich lipid fraction isolated from attenuated Leishmania donovani promastigote induces apoptosis in mouse and human melanoma cells in vitro.

Mol Cell Biochem 2006 Oct 23;290(1-2):113-23. Epub 2006 May 23.

Cellular Biochemistry Division, Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.

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October 2006