Publications

Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives.
J Histochem Cytochem 2018 Feb 10;66(2):121-135. Epub 2017 Nov 10.
Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.



A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue.
Lab Invest 2016 Oct 22;96(10):1116-27. Epub 2016 Aug 22.
Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms.
J Natl Cancer Inst 2015 Nov 14;107(11). Epub 2015 Sep 14.
Division of Cancer Epidemiology and Genetics (JDF, SK, JSC, MGC, MCF, DB, PS, LEM, LPO, ARB, AP, JFFJr, SJC, NC, NR, DTS), Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research (KY, JYC, SMH), and Cancer and Inflammation Program (MLN), National Cancer Institute, Bethesda, MD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School, Edinburgh UK (JDF); CIBERESP, CIBER Epidemiologia y Salud Publica, Madrid, Spain (MK, AT, JL); Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain (MK); Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain (MK); Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK (MGC); Spanish National Cancer Research Centre (CNIO), Madrid, Spain (FXR, NM); Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain (FXR, CS); Maine Cancer Registry, Augusta, ME (MS); Vermont Cancer Registry, Burlington, VT (AJ); Geisel School of Medicine at Dartmouth, Hanover, NH (MRK, AS); New Hampshire Department of Health and Human Services, Concord, NH (KRA); Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc. (formerly SAIC-Frederick, Inc.), Frederick National Laboratory for Cancer Research, Frederick, MD (PL); Molecular Epidemiology Group, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias, Spain (AT); Hospital Ramón y Cajal, Elche, Madrid, Spain (AC); Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Spain (RGC).


The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease.
Cancer Res 2014 Oct;74(20):5808-18
Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

microRNA alterations driving acute and late stages of radiation-induced fibrosis in a murine skin model.
Int J Radiat Oncol Biol Phys 2014 Sep 28;90(1):44-52. Epub 2014 Jun 28.
Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University Hospital, Philadelphia, Pennsylvania. Electronic address:

Multiplex quantitative measurement of mRNAs from fixed tissue microarray sections.
Appl Immunohistochem Mol Morphol 2014 May-Jun;22(5):323-30
*Pathogenetics Unit ‡Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda †Fischell Department of Bioengineering and the Institute for Systems Research §Department of Mechanical Engineering, University of Maryland, College Park, MD.

Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer.
BMC Cancer 2014 Jul 28;14:545. Epub 2014 Jul 28.
Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, 146-92 Dogok-Dong, Gangnam-Gu, Seoul 135-720, South Korea.

CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.
Cancer Res 2014 May 19;74(10):2785-95. Epub 2014 Mar 19.
Authors' Affiliations: Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics; Pediatric Oncology Branch; Laboratory of Pathology; Division of Cancer Control and Population Sciences; Laboratory of Experimental Carcinogenesis, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda; Laboratory of Proteomics and Analytical Technologies, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research; Laboratory of Protein Dynamics and Signaling and Laboratory of Cell & Developmental Signaling, NCI-Frederick, Frederick, Maryland; Keck School of Medicine, University of Southern California, Los Angeles, California; University of Hawaii Cancer Center, Honolulu, Hawaii; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa; and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota

Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry.
J Transl Med 2013 Aug 8;11:185. Epub 2013 Aug 8.
Tissue Array Research Program & Applied Molecular Pathology Lab, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.


Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer.
Hum Pathol 2013 Apr 12;44(4):472-9. Epub 2012 Oct 12.
Tissue Array Research Program and Applied Molecular Pathology Laboratory, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4605, USA.

Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer.
J Natl Cancer Inst 2013 Jan 23;105(1):69-73. Epub 2012 Dec 23.
Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 8717 Grovemont Cir, Bethesda, MD 20892-4605, USA.

Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses.
J Immunol 2012 Jun 21;188(12):6055-62. Epub 2012 May 21.
Gastrointestinal Malignancy Section, Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.


Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections.
J Histochem Cytochem 2011 Apr 10;59(4):356-65. Epub 2011 Feb 10.
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Identification of EpCAM as a molecular target of prostate cancer stroma.
Am J Pathol 2009 Dec 22;175(6):2277-87. Epub 2009 Oct 22.
Pathogenetics Unit, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4605, USA.



Cell-cycle protein expression in a population-based study of ovarian and endometrial cancers.
Front Oncol 2015 9;5:25. Epub 2015 Feb 9.
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA.

A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications.
J Histochem Cytochem 2016 07 24;64(7):425-40. Epub 2016 May 24.
Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (CP, J-YC, KY, CHC, AS, KTM, WAS, SMH)

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