Kris V Kowdley

Kris V Kowdley

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Kris V Kowdley

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Correction: ACG Clinical Guideline: Hereditary Hemochromatosis.

Am J Gastroenterol 2019 Nov 11. Epub 2019 Nov 11.

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http://dx.doi.org/10.14309/ajg.0000000000000469DOI Listing
November 2019

Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis.

Clin Gastroenterol Hepatol 2019 Sep 4;17(10):2076-2084.e2. Epub 2019 Jan 4.

Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The Netherlands; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193000
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http://dx.doi.org/10.1016/j.cgh.2018.12.028DOI Listing
September 2019

ACG Clinical Guideline: Hereditary Hemochromatosis.

Am J Gastroenterol 2019 Aug;114(8):1202-1218

Department of Medicine and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California.

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http://dx.doi.org/10.14309/ajg.0000000000000315DOI Listing
August 2019

Current perspectives into the evaluation and management of hepatitis B: a review.

Hepatobiliary Surg Nutr 2019 Aug;8(4):361-369

Liver Care Network, Swedish Medical Center, Seattle, WA, USA.

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http://dx.doi.org/10.21037/hbsn.2019.02.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700007PMC
August 2019

Pediatric cholestatic liver disease: Successful transition of care.

Cleve Clin J Med 2019 Jul;86(7):454-464

Director of the Metabolic Center, Texas Liver Institute, University of Texas Health, San Antonio, TX, USA.

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http://dx.doi.org/10.3949/ccjm.86a.18140DOI Listing
July 2019

Financial Compensation For Hepatologists in Different Practice Settings.

Hepatology 2019 Jun 12;69(6):2664-2671. Epub 2019 Mar 12.

South Denver Gastroenterology, Denver, CO.

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http://dx.doi.org/10.1002/hep.30488DOI Listing
June 2019

Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis.

J Leukoc Biol 2019 May 5;105(5):1015-1026. Epub 2019 Mar 5.

Organ Care Research and Liver Care Network, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/JLB.3A0318-108RDOI Listing
May 2019

Obeticholic acid in primary biliary cholangitis: where we stand.

Curr Opin Gastroenterol 2019 May;35(3):191-196

Liver Care Network, Swedish Medical Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/MOG.0000000000000525DOI Listing
May 2019

Mechanisms and Treatments of Pruritus in Primary Biliary Cholangitis.

Semin Liver Dis 2019 May 8;39(2):209-220. Epub 2019 Mar 8.

Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, Washington.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1679918
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http://dx.doi.org/10.1055/s-0039-1679918DOI Listing
May 2019

Epidemiologic features of a large hepatitis C cohort evaluated in a major health system in the western United States.

Ann Hepatol 2019 Mar - Apr;18(2):360-365. Epub 2019 Apr 17.

Liver Care Network and Organ Transplant Program, Swedish Medical Center, Seattle, WA, USA; Providence Health & Services, Renton, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.aohep.2018.12.003DOI Listing
April 2019

Serum ferritin as a biomarker for NAFLD: ready for prime time?

Hepatol Int 2019 03 9;13(2):110-112. Epub 2019 Feb 9.

Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA, 98104, USA.

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http://link.springer.com/10.1007/s12072-019-09934-7
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http://dx.doi.org/10.1007/s12072-019-09934-7DOI Listing
March 2019

Diagnosis and Management of Primary Biliary Cholangitis.

Am J Gastroenterol 2019 01;114(1):48-63

NYU Langone Health, New York, NY, 10016, USA.

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http://dx.doi.org/10.1038/s41395-018-0390-3DOI Listing
January 2019

You are what you wheat: effects of a whole-wheat diet compared with a refined-wheat diet on hepatic steatosis.

Am J Clin Nutr 2018 12;108(6):1162-1163

Liver Care Network, Swedish Medical Center, Seattle, WA.

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https://academic.oup.com/ajcn/article/108/6/1162/5239904
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http://dx.doi.org/10.1093/ajcn/nqy300DOI Listing
December 2018

Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.

Clin Liver Dis 2018 02 18;22(1):23-37. Epub 2017 Oct 18.

Swedish Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA 98104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2017.08.007DOI Listing
February 2018

Chronic Hepatitis C in Elderly Patients: Current Evidence with Direct-Acting Antivirals.

Drugs Aging 2018 02;35(2):117-122

Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA, 98104, USA.

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http://dx.doi.org/10.1007/s40266-017-0515-1DOI Listing
February 2018

Reviewing the Risk of Colorectal Cancer in Inflammatory Bowel Disease After Liver Transplantation for Primary Sclerosing Cholangitis.

Inflamm Bowel Dis 2018 01;24(2):269-276

Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, Washington.

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http://dx.doi.org/10.1093/ibd/izx056DOI Listing
January 2018

An Update on the Treatment and Follow-up of Patients with Primary Biliary Cholangitis.

Clin Liver Dis 2017 11 26;21(4):709-723. Epub 2017 Jul 26.

Department of Organ Transplant & Liver Center, Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, 1124 Columbia Street, WA 98101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2017.06.005DOI Listing
November 2017

New developments in the treatment of primary biliary cholangitis - role of obeticholic acid.

Ther Clin Risk Manag 2017 21;13:1053-1060. Epub 2017 Aug 21.

Liver Care Network, Swedish Medical Center, Seattle, WA, USA.

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http://dx.doi.org/10.2147/TCRM.S113052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572954PMC
August 2017

Third-trimester tenofovir to prevent mother-to-child hepatitis B virus transmission.

Indian J Med Res 2017 07;146(1):1-4

Liver Care Network & Organ Care Research, Swedish Medical Center, Seattle, WA, USA.

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http://dx.doi.org/10.4103/ijmr.IJMR_315_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719592PMC
July 2017

Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection.

N Engl J Med 2017 06;376(22):2134-2146

From Hospital Saint Joseph, Marseille (M.B.), and University Hospital of Bordeaux, Pessac (V.L.) - both in France; Henry Ford Health System, Detroit (S.C.G.); Northwestern University, Chicago (S.L.F.); Ottawa Hospital Research Institute, Ottawa (C.L.C.), and St. Paul's Hospital, Vancouver, BC (A.R.) - both in Canada; Huntington Medical Research Institutes, Pasadena (M.T.), Cedars-Sinai Medical Center, Los Angeles (T.T.T.), and Gilead Sciences, Foster City (R.H.H., L.M.S., H.D.-S., E.S., J.Z., K.C.H., G.M.S., D.M.B., J.G.M.) - all in California; Digestive Disease Associates, Catonsville, MD (N.R.); Baylor College of Medicine, Houston (J.M.V.); Monash Health and Monash University, Clayton, VIC (S.P.), and Royal Prince Alfred Hospital, Sydney (S.I.S.) - both in Australia; Icahn School of Medicine at Mount Sinai (M.B.B.) and Columbia University Medical Center (E.C.V.) - both in New York; ifi-Institute for Interdisciplinary Medicine, Hamburg (P.B.), Hannover Medical School, Hannover (M.P.M.), and Johann Wolfgang Goethe University Medical Center, Frankfurt (S.Z.) - all in Germany; University of Washington (C.S.L.) and Swedish Medical Center (K.V.K.) - both in Seattle; Gastro One, Germantown, TN (Z.H.Y.); Beth Israel Deaconess Medical Center, Boston (M.P.C.); University of Miami, Miami (E.R.S.); and University of Pennsylvania, Philadelphia (K.R.R.).

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http://dx.doi.org/10.1056/NEJMoa1613512DOI Listing
June 2017

Developing clinical research in a clinical hepatology practice.

Clin Liver Dis (Hoboken) 2017 Jun 29;9(6):147-149. Epub 2017 Jun 29.

Liver Care Network and Organ Care Research Swedish Medical Center Seattle WA.

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http://dx.doi.org/10.1002/cld.639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467235PMC
June 2017

Curcumin and Turmeric Modulate the Tumor-Promoting Effects of Iron In Vitro.

Nutr Cancer 2017 Apr 27;69(3):481-489. Epub 2017 Jan 27.

b Organ Care Research and Liver Care Network , Swedish Medical Center , Seattle , Washington , USA.

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http://dx.doi.org/10.1080/01635581.2017.1274407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955394PMC
April 2017

Update on hepatitis C treatment: systematic review of clinical trials.

Minerva Gastroenterol Dietol 2017 Mar 21;63(1):62-73. Epub 2016 Oct 21.

Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, WA, USA -

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http://dx.doi.org/10.23736/S1121-421X.16.02345-XDOI Listing
March 2017

Nutritional Approaches to Achieve Weight Loss in Nonalcoholic Fatty Liver Disease.

Adv Nutr 2017 Mar 15;8(2):253-265. Epub 2017 Mar 15.

Swedish Liver Care Network, Swedish Medical Center, Seattle, WA.

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http://dx.doi.org/10.3945/an.116.013730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347099PMC
March 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

Evaluation of proton pump inhibitor use on treatment outcomes with ledipasvir and sofosbuvir in a real-world cohort study.

Hepatology 2016 12 5;64(6):1893-1899. Epub 2016 Oct 5.

Division of Gastroenterology/Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/hep.28782DOI Listing
December 2016

Association between metabolic syndrome and liver histology among NAFLD patients without diabetes.

BMJ Open Gastroenterol 2016 9;3(1):e000114. Epub 2016 Nov 9.

Benaroya Research Institute, Seattle, Washington, USA; Swedish Medical Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1136/bmjgast-2016-000114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128831PMC
November 2016

Iron Overload in Patients With Chronic Liver Disease.

Authors:
Kris V Kowdley

Gastroenterol Hepatol (N Y) 2016 Nov;12(11):695-698

Director, Liver Care Network and Organ Care Research Swedish Medical Center Seattle, Washington.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193089PMC
November 2016

Dual daclatasvir and sofosbuvir for treatment of genotype 3 chronic hepatitis C virus infection.

Expert Rev Gastroenterol Hepatol 2016 2;10(1):13-20. Epub 2015 Dec 2.

a Department of Medicine and Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , CA , USA.

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http://dx.doi.org/10.1586/17474124.2016.1116937DOI Listing
September 2016

The Effects of Alcohol on Other Chronic Liver Diseases.

Clin Liver Dis 2016 Aug 5;20(3):581-94. Epub 2016 Apr 5.

Swedish Liver Care Network, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA 98104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2016.02.013DOI Listing
August 2016

Comparative efficacy of interventions on nonalcoholic fatty liver disease (NAFLD): A PRISMA-compliant systematic review and network meta-analysis.

Medicine (Baltimore) 2016 Aug;95(32):e4529

aClinical Pharmacy Research Unit (CPRU), Department of Clinical Pharmacy, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand bSchool of Pharmacy, Monash University Malaysia, Selangor, Malaysia cCenter of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok dDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok eCenter of Health Outcome Research and Therapeutic Safety, School of Pharmaceutical Sciences,University of Phayao, Phayao fSection for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand gLiver Care Network and Organ Care Research, Swedish Medical Center, Seattle hSchool of Pharmacy, University of Wisconsin, Madison, WI iSchool of Population Health, University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1097/MD.0000000000004529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985329PMC
August 2016

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.

N Engl J Med 2016 Aug;375(7):631-43

From University Hospitals KU Leuven, Leuven, Belgium (F.N.); University of Bologna, Bologna (P.A., G.M.), Program for Autoimmune Liver Disease, International Center for Digestive Health, Department of Medicine and Surgery, University of Milan-Bicocca, Milan (P.I.), Humanitas Clinical and Research Center, Rozzano (P.I.), and University of Padua, Padua (A.F.) - all in Italy; Royal Prince Alfred Hospital, Camperdown, NSW, Australia (S.I.S.); University of California Davis Medical Center, Sacramento (C.B.), Scripps Clinic, La Jolla (P.J.P.), and Intercept Pharmaceuticals, San Diego (R.H.-R., T.M., S.S., R.P., L.M., M.P., D.S.) - all in California; Radboud University Nijmegen Medical Center, Nijmegen (J.P.H.D.), University of Amsterdam, Amsterdam (U.B.), University Medical Center Utrecht, Utrecht (K.J.E.), and University Medical Center Rotterdam, Rotterdam (B.H.) - all in the Netherlands; Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland (J.R.); Medical University of Vienna, Vienna (M.T.); Newcastle University Medical School, Newcastle upon Tyne (D.E.J.), and the Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham (G.M.H.) - both in the United Kingdom; Liver Center Munich, Department of Medicine II, University of Munich, Munich, Germany (S.H.); Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond (V.L.), and the Liver Institute of Virginia, Newport News (M.S.) - all in Virginia; the Liver Unit, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas del Instituto de Salud Carlos III, Barcelona (V.V.); Centre Hospitalier de l'Université de Montréal-St. Luc, Montreal (C.V.); University Health Network Toronto Western Hospital, Toronto (H.S.); Arizona State University, Tempe (K.D.L.); Sahlgrenska Academy, University of Gothenburg,

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http://dx.doi.org/10.1056/NEJMoa1509840DOI Listing
August 2016

Mitochondrial DNA from hepatocytes as a ligand for TLR9: Drivers of nonalcoholic steatohepatitis?

World J Gastroenterol 2016 Aug;22(31):6965-71

Priya Handa, Akhila Vemulakonda, Kris V Kowdley, Senior Research Scientist, Organ Care Research and Liver Care Network, Swedish Medical Center, Seattle, WA 98104, United States.

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http://dx.doi.org/10.3748/wjg.v22.i31.6965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988306PMC
August 2016

Disruption of Iron Regulation after Radiation and Donor Cell Infusion.

Biol Blood Marrow Transplant 2016 07 7;22(7):1173-1181. Epub 2016 Apr 7.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131542PMC
July 2016

Role of ledipasvir/sofosbuvir combination for genotype 1 hepatitis C virus infection.

Hepat Med 2016 28;8:75-80. Epub 2016 Jun 28.

Liver Care Network, Swedish Medical Center, Seattle, WA, USA.

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http://dx.doi.org/10.2147/HMER.S63125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933567PMC
July 2016

Acidophil bodies in nonalcoholic steatohepatitis.

Hum Pathol 2016 06 1;52:28-37. Epub 2016 Feb 1.

Department of Pathology, University of California School of Medicine, San Francisco, San Francisco, CA, United States 94143.

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http://dx.doi.org/10.1016/j.humpath.2016.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304937PMC
June 2016

The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis.

Clin Liver Dis 2016 May 14;20(2):225-43. Epub 2015 Dec 14.

Department of Transplant Hepatology, Swedish Medical Center, 1101, Madison Street, Suite 200, Seattle, WA 98104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2015.10.002DOI Listing
May 2016

Hepatitis B Virus--Specific and Global T-Cell Dysfunction in Chronic Hepatitis B.

Gastroenterology 2016 Mar 10;150(3):684-695.e5. Epub 2015 Dec 10.

Philadelphia Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.11.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766024PMC
March 2016

Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study.

Gut 2016 Feb 7;65(2):321-9. Epub 2015 Jan 7.

National Institute for Health Research (NIHR) Birmingham Liver Biomedical Research Unit (BRU) and Centre for Liver Research, University of Birmingham, Birmingham, UK Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.

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http://dx.doi.org/10.1136/gutjnl-2014-308351DOI Listing
February 2016

A Proton Pump Inhibitor a Day Keeps the Iron Away.

Clin Gastroenterol Hepatol 2016 Jan 15;14(1):153-5. Epub 2015 Sep 15.

Organ Care Research and Liver Care Network, Swedish Medical Center, Seattle, Washington.

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http://dx.doi.org/10.1016/j.cgh.2015.09.007DOI Listing
January 2016

Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice.

Am J Physiol Gastrointest Liver Physiol 2016 Jan 12;310(2):G117-27. Epub 2015 Nov 12.

Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, Washington; Benaroya Research Institute, Seattle, Washington;

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http://dx.doi.org/10.1152/ajpgi.00246.2015DOI Listing
January 2016

Glyceronephosphate O-acyltransferase as a hemochromatosis modifier gene: Another iron in the fire?

Hepatology 2015 Aug 6;62(2):337-9. Epub 2015 May 6.

Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, WA.

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http://dx.doi.org/10.1002/hep.27813DOI Listing
August 2015

Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials.

Hepatology 2015 Jun 18;61(6):1798-808. Epub 2015 Mar 18.

Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA.

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http://dx.doi.org/10.1002/hep.27724DOI Listing
June 2015

It TAK(es) 1 to prevent steatohepatitis and tumorigenesis.

Ann Hepatol 2014 Nov-Dec;13(6):847-9

Benaroya Research Institute, Seattle, Washington, USA; Liver Transplant Care Network, Swedish, Seattle, WA, USA.

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May 2015

ACG Clinical Guideline: Primary Sclerosing Cholangitis.

Am J Gastroenterol 2015 May 14;110(5):646-59; quiz 660. Epub 2015 Apr 14.

Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, Arizona, USA.

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http://gi.org/wp-content/uploads/2015/05/Primary-Sclerosing-
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http://www.nature.com/doifinder/10.1038/ajg.2015.112
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http://dx.doi.org/10.1038/ajg.2015.112DOI Listing
May 2015

ABT-450/ ritonavir and ABT-267 in combination with ABT-333 for the treatment of hepatitis C virus.

Expert Opin Pharmacother 2015 Apr;16(6):929-37

University of Washington School of Medicine , 1959 N.E. Pacific St., Seattle, WA 98195 , USA.

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http://dx.doi.org/10.1517/14656566.2015.1024653DOI Listing
April 2015

Analysis of Subgroup Differences in the ION-3 Trial of Ledipasvir-Sofosbuvir in Chronic Hepatitis C Infection.

Open Forum Infect Dis 2015 Apr 20;2(2):ofv056. Epub 2015 Apr 20.

University of California , San Diego.

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http://dx.doi.org/10.1093/ofid/ofv056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567098PMC
April 2015

Predicting outcome in primary biliary cirrhosis.

Ann Hepatol 2014 Jul-Aug;13(4):316-26

Dept. of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The Netherlands.

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February 2015

Comparison of first- and second-wave DAAs for HCV GT1: efficacy, safety, tolerability, and regimen complexity.

Hepatol Int 2014 Jul 9;8(3):352-64. Epub 2014 Jul 9.

Benaroya Research Institute, University of Washington, 1201 9th Ave, Seattle, WA, 98101, USA.

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http://dx.doi.org/10.1007/s12072-014-9552-6DOI Listing
July 2014

Dairy fat intake is associated with glucose tolerance, hepatic and systemic insulin sensitivity, and liver fat but not β-cell function in humans.

Am J Clin Nutr 2014 Jun 16;99(6):1385-96. Epub 2014 Apr 16.

From the Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Prevention Program (MK and XS) and Biostatistics Program (CD), Seattle, WA; the Division of Metabolism, Endocrinology & Nutrition, Department of Medicine, University of Washington, Seattle, WA (MK and KMU); the Departments of Epidemiology (MK) and Pathology (MMY), University of Washington, Seattle, WA; the University of Washington Northwest Lipid Research Laboratories, Seattle, WA (SM); Benaroya Research Institute, Virginia Mason Medical Center, Seattle, WA (JEN and KVK); the University of Washington Institute of Translational Health Sciences, Seattle, WA (HSC); and the VA Puget Sound Health Care System, Department of Medicine, Division of Endocrinology, Seattle, WA (KMU).

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http://dx.doi.org/10.3945/ajcn.113.075457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021783PMC
June 2014

Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis.

N Engl J Med 2014 May 10;370(20):1879-88. Epub 2014 Apr 10.

From the Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Henry Ford Health Systems, Detroit (S.C.G.); University of Pennsylvania, Philadelphia (K.R.R.); University of California Davis Medical Center, Sacramento (L.R.), University of California at San Diego Medical Center, San Diego (M.C.), Scripps Clinic, La Jolla (P.J.P.), and Gilead Sciences, Foster City (G.M.S., D.A., E.S., R.H.H., P.S.P., W.T.S., J.G.M.) - all in California; Hofstra North Shore-Long Island Jewish School of Medicine, Manhasset, NY (D.E.B.); Texas Liver Institute and University of Texas Health Science Center, San Antonio (E.L.), and Texas Clinical Research Institute, Arlington (R.G.) - both in Texas; Liver Institute of Virginia, Bon Secours Health System, Richmond and Newport News (M.L.S.), Digestive and Liver Disease Specialists, Norfolk (M.R.), and Metropolitan Liver Diseases, Fairfax (V.R.) - all in Virginia; Center for Liver Diseases, School of Medicine, University of Miami, Miami (E.S.); Quality Medical Research, Nashville (R.H.); Saint Louis University, St. Louis (A.M.D.); Duke University Medical Center, Durham (A.J.M.), and University of North Carolina, Chapel Hill (M.W.F.) - both in North Carolina; and Indianapolis Gastroenterology Research Foundation, Indianapolis (D.P.).

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http://dx.doi.org/10.1056/NEJMoa1402355DOI Listing
May 2014

ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis.

N Engl J Med 2014 May 11;370(21):1973-82. Epub 2014 Apr 11.

From the Texas Liver Institute-University of Texas Health Science Center, San Antonio (F.P.); Henri Mondor Hospital, Assistance Publique-Hôpitaux de Paris, University Paris-Est, INSERM Unité 955, Créteil, France (C.H.); AbbVie, North Chicago, IL (R.T., S.S.L., B.D.S.-T., C.A.C., A.L.C., T.P., B.B.); Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Johann Wolfgang Goethe University, Frankfurt (S.Z.), Medizinische Hochschule Hannover, Hannover (H.W.), and Universitätsklinikum Leipzig, Leipzig (T.B.) - all in Germany; Institute of Liver Studies, King's College Hospital, London (K.A.); Liver Institute of Virginia, Newport News (M.L.S.); University of British Columbia, Vancouver, Canada (E.M.Y.); and Liver Unit, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona (X.F.).

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May 2014

Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin.

N Engl J Med 2014 Apr 10;370(17):1594-603. Epub 2014 Apr 10.

From the Toronto Centre for Liver Disease, University of Toronto, Toronto (J.J.F.); Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); AbbVie, North Chicago, IL (E.C., J.X., T.P.-M., B.D.-T., L.L., T.P., B.B.); New York University School of Medicine, New York (S.S.); University of Florida College of Medicine, Gainesville (D.R.N.); Gallipoli Medical Research Foundation and School of Medicine, University of Queensland, Brisbane, Australia (D.C.); Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm (O.W.); and Louisiana Research Center, Shreveport (H.A.).

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http://dx.doi.org/10.1056/NEJMoa1315722DOI Listing
April 2014

Advances in the diagnosis and treatment of nonalcoholic steatohepatitis.

Authors:
Kris V Kowdley

Gastroenterol Hepatol (N Y) 2014 Mar;10(3):184-6

Director Liver Center of Excellence Digestive Disease Institute at Virginia Mason Medical Center Clinical Professor of Medicine University of Washington Seattle, Washington.

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March 2014

Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1.

N Engl J Med 2014 Jan;370(3):222-32

From the Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Texas Liver Institute, University of Texas Health Science Center, San Antonio (E.L., F.P.); AbbVie, North Chicago (D.E.C., W.X., T.P.-M., G.L., L.L., A.K., T.P., B.B.); University of Florida College of Medicine, Gainesville (D.R.N.); J.W. Goethe University, Frankfurt, Germany (S.Z.); University of Colorado Denver, Aurora (G.T.E.); Indiana University, Indianapolis (P.K.); Queen Mary, University of London, Barts Health, London (G.R.F.); and Johns Hopkins University, Baltimore (M.S.S.).

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January 2014