Publications by authors named "Kris Noel Dahl"

55Publications

Piperazine Derivatives Enhance Epithelial Cell Monolayer Permeability by Increased Cell Force Generation and Loss of Cadherin Structures.

ACS Biomater Sci Eng 2020 Jan 13;6(1):367-374. Epub 2019 Dec 13.

Molecular Biophysics and Structural Biology, University of Pittsburgh and Carnegie Mellon University, 3501 Fifth Avenue, Pittsburgh, Pennsylvania 15260, United States.

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January 2020

Cells with Higher Cortical Membrane Tension Are More Sensitive to Lysis by Biosurfactant Di-rhamnolipids.

ACS Biomater Sci Eng 2020 Jan 2;6(1):352-357. Epub 2019 Dec 2.

College of Chemical and Biological Engineering, Zhejiang University, 38 Zheda Road, Hangzhou, Zhejiang 310027, P. R. China.

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January 2020

Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage.

Cell 2020 05 16;181(4):800-817.e22. Epub 2020 Apr 16.

Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany; Cologne Excellence Cluster for Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany. Electronic address:

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May 2020

Quantifying site-specific chromatin mechanics and DNA damage response.

Sci Rep 2018 12 27;8(1):18084. Epub 2018 Dec 27.

Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.

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December 2018

Determining mechanical features of modulated epithelial monolayers using subnuclear particle tracking.

J Cell Sci 2018 06 21;131(12). Epub 2018 Jun 21.

Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA

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June 2018

Length-dependent intracellular bundling of single-walled carbon nanotubes influences retention.

J Mater Chem B 2017 Aug 11;5(32):6657-6665. Epub 2017 Jul 11.

Department of Materials Science and Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3815, USA.

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August 2017

Mechanobiology of Chromatin and the Nuclear Interior.

Cell Mol Bioeng 2016 Jun 11;9(2):268-276. Epub 2016 May 11.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, USA; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, USA.

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June 2016

Dispersed single wall carbon nanotubes do not impact mitochondria structure or function, but technical issues during analysis could yield incorrect results.

J Mater Chem B 2017 Jan 12;5(2):369-374. Epub 2016 Dec 12.

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3815, USA.

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January 2017

Nuclear mechanical resilience but not stiffness is modulated by αII-spectrin.

J Biomech 2016 12 27;49(16):3983-3989. Epub 2016 Oct 27.

Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. Electronic address:

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December 2016

Enhanced intracellular delivery of small molecules and drugs via non-covalent ternary dispersions of single-wall carbon nanotubes.

J Mater Chem B 2016 Feb 25;4(7):1324-1330. Epub 2016 Jan 25.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3815, USA.

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February 2016

Delivering Single-Walled Carbon Nanotubes to the Nucleus Using Engineered Nuclear Protein Domains.

ACS Appl Mater Interfaces 2016 Feb 1;8(5):3524-34. Epub 2016 Feb 1.

Department of Civil and Environmental Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.

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February 2016

Spatially Resolved Quantification of Chromatin Condensation through Differential Local Rheology in Cell Nuclei Fluorescence Lifetime Imaging.

PLoS One 2016 14;11(1):e0146244. Epub 2016 Jan 14.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, Pennsylvania, 15213, United States of America.

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July 2016

Early Passage Dependence of Mesenchymal Stem Cell Mechanics Influences Cellular Invasion and Migration.

Ann Biomed Eng 2016 07 18;44(7):2123-31. Epub 2015 Nov 18.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA, 15213, USA.

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July 2016

Distribution of single wall carbon nanotubes in the Xenopus laevis embryo after microinjection.

J Appl Toxicol 2016 Apr 28;36(4):568-78. Epub 2015 Oct 28.

Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.

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April 2016

Differential sub-cellular processing of single-wall carbon nanotubes via interfacial modifications.

J Mater Chem B 2015 Aug 6;3(30):6274-6284. Epub 2015 Jul 6.

Department of Materials Science and Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3815, USA.

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August 2015

Nuclear stiffening and chromatin softening with progerin expression leads to an attenuated nuclear response to force.

Soft Matter 2015 Aug 14;11(32):6412-8. Epub 2015 Jul 14.

Department of Chemical Engineering, Carnegie Mellon University, USA.

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August 2015

Developing Xenopus embryos recover by compacting and expelling single wall carbon nanotubes.

J Appl Toxicol 2016 Apr 7;36(4):579-85. Epub 2015 Jul 7.

Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.

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April 2016

Subcellular Partitioning and Analysis of Gd3+-Loaded Ultrashort Single-Walled Carbon Nanotubes.

ACS Appl Mater Interfaces 2015 Jul 2;7(27):14593-602. Epub 2015 Jul 2.

‡Department of Chemistry and Smalley Center for Nanoscale Science and Technology, Rice University, Houston, Texas 77251, United States.

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July 2015

Nuclear stiffening inhibits migration of invasive melanoma cells.

Cell Mol Bioeng 2014 Dec;7(4):544-551

Department of Biomedical Engineering, Carnegie Melon University, Pittsburgh, PA 15213.

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December 2014

Interfacial binding and aggregation of lamin A tail domains associated with Hutchinson-Gilford progeria syndrome.

Biophys Chem 2014 Dec 23;195:43-8. Epub 2014 Aug 23.

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, United States; Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, United States. Electronic address:

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December 2014

Active cytoskeletal force and chromatin condensation independently modulate intranuclear network fluctuations.

Integr Biol (Camb) 2014 May;6(5):523-31

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, USA.

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May 2014

Actin reorganization through dynamic interactions with single-wall carbon nanotubes.

ACS Nano 2014 Jan 24;8(1):188-97. Epub 2013 Dec 24.

Molecular Cell Biomechanics Laboratory, Departments of Bioengineering and Mechanical Engineering, University of California , Berkeley, California 94720, United States.

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January 2014

Hutchinson-Gilford progeria syndrome alters nuclear shape and reduces cell motility in three dimensional model substrates.

Integr Biol (Camb) 2013 Mar;5(3):569-77

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA 15213, USA.

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March 2013

Not all protein-mediated single-wall carbon nanotube dispersions are equally bioactive.

Nanoscale 2012 Dec;4(23):7425-34

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA.

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December 2012

Modeling nuclear blebs in a nucleoskeleton of independent filament networks.

Cell Mol Bioeng 2012 Mar 19;5(1):73-81. Epub 2011 Aug 19.

Department of Chemical Engineering, Carnegie Mellon University.

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March 2012

Cells take up and recover from protein-stabilized single-wall carbon nanotubes with two distinct rates.

ACS Nano 2012 Apr 4;6(4):3481-90. Epub 2012 Apr 4.

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3890, United States.

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April 2012

Mechanical characterization of adult stem cells from bone marrow and perivascular niches.

J Biomech 2012 Apr 18;45(7):1280-7. Epub 2012 Feb 18.

Department of Biomedical Engineering, Carnegie Mellon University, Pittsburg, PA 15213, United States.

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April 2012

Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration.

J Nanobiotechnology 2011 Sep 30;9:45. Epub 2011 Sep 30.

Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.

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September 2011

Structure and stability of the lamin A tail domain and HGPS mutant.

J Struct Biol 2011 Sep 24;175(3):425-33. Epub 2011 May 24.

Laboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Mass. Ave., Room 1-235A&B, Cambridge, MA 02139, USA.

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September 2011

Quantification of uptake and localization of bovine serum albumin-stabilized single-wall carbon nanotubes in different human cell types.

Small 2011 Aug 31;7(16):2348-55. Epub 2011 May 31.

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213-3890, USA.

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August 2011

Nucleoskeleton mechanics at a glance.

J Cell Sci 2011 Mar;124(Pt 5):675-8

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA.

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March 2011

Beyond lamins other structural components of the nucleoskeleton.

Methods Cell Biol 2010 ;98:97-119

Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.

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December 2010

Carbon nanotubes reorganize actin structures in cells and ex vivo.

ACS Nano 2010 Aug;4(8):4872-8

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213-3890, USA.

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August 2010

Stabilization of the spectrin-like domains of nesprin-1α by the evolutionarily conserved "adaptive" domain.

Cell Mol Bioeng 2010 Jun;3(2):139-150

Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.

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June 2010

Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics.

Microcirculation 2010 Apr;17(3):179-91

Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

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April 2010

In the middle of it all: mutual mechanical regulation between the nucleus and the cytoskeleton.

J Biomech 2010 Jan 4;43(1):2-8. Epub 2009 Oct 4.

Carnegie Mellon University, Department of Biomedical Engineering, 5000 Forbes Avenue, Pittsburgh, PA 15213, United States.

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January 2010

Nuclear mechanotransduction: response of the lamina to extracellular stress with implications in aging.

J Biomech 2008 Nov 21;41(15):3164-70. Epub 2008 Oct 21.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA.

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November 2008

Nuclear shape, mechanics, and mechanotransduction.

Circ Res 2008 Jun;102(11):1307-18

Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA 15213, USA.

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June 2008

Physical plasticity of the nucleus in stem cell differentiation.

Proc Natl Acad Sci U S A 2007 Oct 24;104(40):15619-24. Epub 2007 Sep 24.

Molecular and Cell Biophysics Laboratory, 129 Towne Building, University of Pennsylvania, Philadelphia, PA 19104, USA.

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October 2007

Nuclear mechanics and methods.

Methods Cell Biol 2007 ;83:269-94

Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital,/Harvard Medical School, Boston, Massachusetts 02115, USA.

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August 2007

Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome.

Proc Natl Acad Sci U S A 2006 Jul 26;103(27):10271-10276. Epub 2006 Jun 26.

National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and.

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July 2006

Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling.

Blood Cells Mol Dis 2006 May-Jun;36(3):364-72. Epub 2006 May 11.

Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA.

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November 2006

Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures.

Biophys J 2005 Oct 29;89(4):2855-64. Epub 2005 Jul 29.

Johns Hopkins University, Baltimore, MD 21202, USA.

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October 2005

The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber.

J Cell Sci 2004 Sep 25;117(Pt 20):4779-86. Epub 2004 Aug 25.

Department of Chemical and Biomolecular Engineering, 220 South 33rd Street, University of Pennsylvania, Philadelphia, PA 19104-6393, USA.

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September 2004

Protein 4.2 is critical to CD47-membrane skeleton attachment in human red cells.

Blood 2004 Feb 9;103(3):1131-6. Epub 2003 Oct 9.

Department of Chemical and Biomolecular Engineering and School of Engineering and Applied Science, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA.

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February 2004

Fractional attachment of CD47 (IAP) to the erythrocyte cytoskeleton and visual colocalization with Rh protein complexes.

Blood 2003 Feb 26;101(3):1194-9. Epub 2002 Sep 26.

School of Engineering and Applied Science, Institute for Medicine and Engineering, and Department of Pathology and Laboratory Medicine, University of Pennsylvania, PA 19104, USA.

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February 2003